D-arabinono-1,4-lakton oksidaza
| D-arabinono-1,4-lakton oksidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.3.37 | ||||||||
| CAS broj | 182372-12-9 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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D-arabinono-1,4-lakton oksidaza (EC 1.1.3.37, D-arabinono-gama-lakton oksidaza, ALO) je enzim sa sistematskim imenom D-arabinono-1,4-lakton:kiseonik oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- D-arabinono-1,4-lakton + O2 dehidro-D-arabinono-1,4-lakton +H2O2
Ovaj enzim je flavoprotein (FAD). L-Galaktono-1,4-lakton, L-gulono-1,4-lakton i L-ksilono-1,4-lakton takođe mogu da budu supstrati, dok D-glukono-1,5-lakton, L-arabinono-1,4-lakton, D-galaktono-1,4-lakton i D-gulono-1,4-lakton ne mogu. Sa L-galaktono-1,4-laktonom kao supstratom, produkt je L-askorbat.
Reference
[уреди | уреди извор]- ^ Huh, W.K., Kim, S.T., Yang, K.S., Seok, Y.J., Hah, Y.C. and Kang, S.O. (1994). „Characterisation of D-arabinono-1,4-lactone oxidase from Candida albicans ATCC 10231”. Eur. J. Biochem. 225: 1073—1079. PMID 7957197.
- ^ Huh, W.K., Lee, B.H., Kim, S.T., Kim, Y.R., Rhie, G.E., Baek, Y.W., Hwang, C.S., Lee, J.S. and Kang, S.O. (1998). „D-Erythroascorbic acid is an important antioxidant molecule in Saccharomyces cerevisiae”. Mol. Microbiol. 30: 895—903. PMID 10094636.
- ^ Lee, B.H., Huh, W.K., Kim, S.T., Lee, J.S. and Kang, S.O. (1999). „Bacterial production of D-erythroascorbic acid and L-ascorbic acid through functional expression of Saccharomyces cerevisiae D-arabinono-1,4-lactone oxidase in Escherichia coli”. Appl. Environ. Microbiol. 65: 4685—4687. PMID 10508108.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
[уреди | уреди извор]- D-arabinono-1,4-lactone+oxidase на US National Library of Medicine Medical Subject Headings (MeSH)
