Preparing to stop an inappropriate action requires keeping in mind the task goal and using this t... more Preparing to stop an inappropriate action requires keeping in mind the task goal and using this to influence the action control system. We tested the hypothesis that different sub-regions of prefrontal cortex show different temporal profiles consistent with dissociable contributions to preparing-to-stop, with dorsolateral prefrontal cortex (DLPFC) representing the task goal and ventrolateral prefrontal cortex (VLPFC) implementing action control. Five human subjects were studied using electrocorticography recorded from subdural grids over right lateral frontal cortex. On each trial, a task cue instructed the subject whether stopping might be needed or not (Maybe Stop or No Stop), followed by a go cue, and on some Maybe Stop trials, a subsequent stop signal. We focused on go trials, comparing Maybe Stop with No Stop. In the DLPFC, most subjects had an increase in high gamma activity following the task cue and the go cue. By contrast in the VLPFC, all subjects had activity after the go...
Epileptic disorders : international epilepsy journal with videotape, 2006
... A Ikeda, K Källén, C Kellinghaus, P Kotagal, D Lachhwani, T Loddenkemper, J Mani, R Matsumoto... more ... A Ikeda, K Källén, C Kellinghaus, P Kotagal, D Lachhwani, T Loddenkemper, J Mani, R Matsumoto, G Möddel, D Nair, S Noachtar, CA O'Donovan, S Rona, F Rosenow, S Schuele, CA Szabo, N Tandon, A Tanner, P Widdess-Walsh , Epilepsy Center, Cleveland Clinic Foundation ...
Preparing to stop an inappropriate action requires keeping in mind the task goal and using this t... more Preparing to stop an inappropriate action requires keeping in mind the task goal and using this to influence the action control system. We tested the hypothesis that different sub-regions of prefrontal cortex show different temporal profiles consistent with dissociable contributions to preparing-to-stop, with dorsolateral prefrontal cortex (DLPFC) representing the task goal and ventrolateral prefrontal cortex (VLPFC) implementing action control. Five human subjects were studied using electrocorticography recorded from subdural grids over right lateral frontal cortex. On each trial, a task cue instructed the subject whether stopping might be needed or not (Maybe Stop or No Stop), followed by a go cue, and on some Maybe Stop trials, a subsequent stop signal. We focused on go trials, comparing Maybe Stop with No Stop. In the DLPFC, most subjects had an increase in high gamma activity following the task cue and the go cue. By contrast in the VLPFC, all subjects had activity after the go...
Epileptic disorders : international epilepsy journal with videotape, 2006
... A Ikeda, K Källén, C Kellinghaus, P Kotagal, D Lachhwani, T Loddenkemper, J Mani, R Matsumoto... more ... A Ikeda, K Källén, C Kellinghaus, P Kotagal, D Lachhwani, T Loddenkemper, J Mani, R Matsumoto, G Möddel, D Nair, S Noachtar, CA O'Donovan, S Rona, F Rosenow, S Schuele, CA Szabo, N Tandon, A Tanner, P Widdess-Walsh , Epilepsy Center, Cleveland Clinic Foundation ...
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