IntroductionThere is evidence to suggest that blood viscosity (BV) is involved in several patholo... more IntroductionThere is evidence to suggest that blood viscosity (BV) is involved in several pathological processes. In this review, we evaluated the different methods of BV acquisition, analyzing the sample storage time, the storage temperature, the acquisition time, the acquisition temperature, sample volume, and shear rates, in order to standardize this technique.MethodsWe selected 50 articles with methods of obtaining BV, evaluating pathologies through BV, comparing rheological equipment, monitoring, and regulating BV.Results and conclusionMeasurements should be obtained as soon as possible, to reduce hemorheological changes. It is necessary to refrigerate them at 4°C when the storage time is long. The acquisition time is related to the equipment used. BV measurements at 37°C will represent the real BV in vivo more faithfully. In order to understand the BV phenomena, the shear rates must be between 0.1 and 1000 s‐1. There is a wide variety of equipment available for measuring the BV.
The COVID-19 pandemic posed a significant impediment to experimental research, leading several re... more The COVID-19 pandemic posed a significant impediment to experimental research, leading several researchers to adapt psychophysical data acquisition. With the development and proliferation of information technology, paper-based organizational processes have gradually begun to be replaced by computer-based equivalents. This study describes how we developed, analyzed data, and validated the temporal bisection task in a remote data acquisition scenario. We implemented the data acquisition using the open science software OpenSesame, in conjunction with the JATOS platform. We described in detail all the steps to use our codes, which we made available for reuse. We acquired data from 28 participants using the remote acquisition system and compared them with data obtained in person (from Penney et al., 2000). Our remote data showed compatible results with live experiments, suggesting that the modality of data acquisition (remote or live) does not influence the results.
There is evidence to suggest that blood viscosity (BV) is involved in several pathological proces... more There is evidence to suggest that blood viscosity (BV) is involved in several pathological processes. In this review, we evaluated the different methods of BV acquisition, analyzing the sample storage time, the storage temperature, the acquisition time, the acquisition temperature, sample volume, and shear rates, in order to standardize this technique.
Much evidence suggests that blood viscosity (BV) is involved in some pathological processes, such... more Much evidence suggests that blood viscosity (BV) is involved in some pathological processes, such as myocardial ischemia, strokes, and cognitive deficits. In addition, there are data pointing to the higher BV in individuals with sleep apnea, hyperlipidemia and hyperproteinemia, with arterial hypertension, and in dehydrated individuals. 1 Some of the known risk factors that alter BV in pathophysiological processes are diabetes, smoking, aging, and obesity. 2 Blood viscosity is a general measure of intrinsic resistance to blood flow and is determined mainly by hematocrit, plasma viscosity, and the deformation and the aggregation of erythrocytes. Moreover, BV varies with shear rate such as non-Newtonian fluid. Therefore, it is an important property for the regulation of blood rheological conditions (for producing resistance to fluid deformations) to determine blood flow and to determine tissue perfusion. 1,3 Because it is an intrinsic property of blood flow and tissue perfusion, changes in BV and its rheological parameters can promote micro-and macrovascular damage and, as a consequence, major cardiovascular events. 2 The blood represents about 7% of an individual's body weight and consists of plasma (a liquid part of the blood that contains various substances), red blood cells (RBCs), leukocytes (white blood cells), and platelets (cell fragments). Its essential function is the transport of substances, such as hydrogen, oxygen, electrolytes, and nutritional substances, in addition to products of cellular metabolism. RBCs pass through capillaries in the circulatory system and are exposed to various shear stresses in the blood flow. One of the unique features is the ability to change shape in response to external forces. This important phenomenon defines its mechanical behavior and function, since it is known that the reduced deformability
IntroductionThere is evidence to suggest that blood viscosity (BV) is involved in several patholo... more IntroductionThere is evidence to suggest that blood viscosity (BV) is involved in several pathological processes. In this review, we evaluated the different methods of BV acquisition, analyzing the sample storage time, the storage temperature, the acquisition time, the acquisition temperature, sample volume, and shear rates, in order to standardize this technique.MethodsWe selected 50 articles with methods of obtaining BV, evaluating pathologies through BV, comparing rheological equipment, monitoring, and regulating BV.Results and conclusionMeasurements should be obtained as soon as possible, to reduce hemorheological changes. It is necessary to refrigerate them at 4°C when the storage time is long. The acquisition time is related to the equipment used. BV measurements at 37°C will represent the real BV in vivo more faithfully. In order to understand the BV phenomena, the shear rates must be between 0.1 and 1000 s‐1. There is a wide variety of equipment available for measuring the BV.
The COVID-19 pandemic posed a significant impediment to experimental research, leading several re... more The COVID-19 pandemic posed a significant impediment to experimental research, leading several researchers to adapt psychophysical data acquisition. With the development and proliferation of information technology, paper-based organizational processes have gradually begun to be replaced by computer-based equivalents. This study describes how we developed, analyzed data, and validated the temporal bisection task in a remote data acquisition scenario. We implemented the data acquisition using the open science software OpenSesame, in conjunction with the JATOS platform. We described in detail all the steps to use our codes, which we made available for reuse. We acquired data from 28 participants using the remote acquisition system and compared them with data obtained in person (from Penney et al., 2000). Our remote data showed compatible results with live experiments, suggesting that the modality of data acquisition (remote or live) does not influence the results.
There is evidence to suggest that blood viscosity (BV) is involved in several pathological proces... more There is evidence to suggest that blood viscosity (BV) is involved in several pathological processes. In this review, we evaluated the different methods of BV acquisition, analyzing the sample storage time, the storage temperature, the acquisition time, the acquisition temperature, sample volume, and shear rates, in order to standardize this technique.
Much evidence suggests that blood viscosity (BV) is involved in some pathological processes, such... more Much evidence suggests that blood viscosity (BV) is involved in some pathological processes, such as myocardial ischemia, strokes, and cognitive deficits. In addition, there are data pointing to the higher BV in individuals with sleep apnea, hyperlipidemia and hyperproteinemia, with arterial hypertension, and in dehydrated individuals. 1 Some of the known risk factors that alter BV in pathophysiological processes are diabetes, smoking, aging, and obesity. 2 Blood viscosity is a general measure of intrinsic resistance to blood flow and is determined mainly by hematocrit, plasma viscosity, and the deformation and the aggregation of erythrocytes. Moreover, BV varies with shear rate such as non-Newtonian fluid. Therefore, it is an important property for the regulation of blood rheological conditions (for producing resistance to fluid deformations) to determine blood flow and to determine tissue perfusion. 1,3 Because it is an intrinsic property of blood flow and tissue perfusion, changes in BV and its rheological parameters can promote micro-and macrovascular damage and, as a consequence, major cardiovascular events. 2 The blood represents about 7% of an individual's body weight and consists of plasma (a liquid part of the blood that contains various substances), red blood cells (RBCs), leukocytes (white blood cells), and platelets (cell fragments). Its essential function is the transport of substances, such as hydrogen, oxygen, electrolytes, and nutritional substances, in addition to products of cellular metabolism. RBCs pass through capillaries in the circulatory system and are exposed to various shear stresses in the blood flow. One of the unique features is the ability to change shape in response to external forces. This important phenomenon defines its mechanical behavior and function, since it is known that the reduced deformability
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Papers by Marcel Valério de Arruda