Departamento de Pediatria

Anemia de dificil tratamento e uma manifestacao clinica comumente observada nos pacientes portadores de doencas inflamatorias intestinais, sendo responsavel por prejuizo significativo na qualidade de vida destes pacientes. O objetivo deste estudo foi avaliar, nos pacientes com doenca inflamatoria intestinal, a prevalencia e os fatores de risco da anemia suas possiveis etiologias. Neste estudo de corte prospectivo observacional foram recrutados: 100 pacientes portadores de Doenca de Crohn e 100 pacientes portadores de Retocolite ulcerativa, diagnosticados e acompanhados regularmente no Centro de Doencas Inflamatorias Intestinais do Hospital Universitario da Universidade Federal de Juiz de Fora, para avaliacao hematologica, bioquimica e imunologica. Foram obtidas amostras de sangue (20 ml) e realizados os seguintes exames em todos os pacientes: hemograma completo, VGM, HGM, CHGM, plaquetas, acido folico, vitamina B12, reticulocitos, indice de saturacao da transferrina, ferritina, ferr...

Anemia is common in inflammatory bowel disease (IBD). However, epidemiological studies of nonwestern IBD populations are limited and may be confounded by demographic, socioeconomic, and disease-related influences. This study evaluated the prevalence, risk factors, and etiology of anemia in Brazilian outpatients with IBD.Methods. In this cross-sectional study, 100 Crohn’s disease (CD) patients and 100 ulcerative colitis (UC) subjects were assessed. Anemia workup included complete blood count, ferritin, transferrin saturation, serum levels of folic acid and vitamin B12, and C-reactive protein (CRP) concentration.Results. The overall prevalence of anemia in IBD was 21%. There was no significant difference in the prevalence of anemia between CD subjects (24%) and UC (18%). Moderate disease activity (OR: 3.48, 95% CI, 1.95–9.64,P=0.002) and elevated CRP levels (OR: 1.8, 95% CI, 1.04–3.11,P=0.02) were independently associated with anemia. The most common etiologies of anemia found in both...