Publications Related to Me by safinaz mohd khialdin
CyberSecurity Malaysia, 2017
This is a book on Cyberparenting by CyberSecurity Malaysia (CSM) and Dr. Meriam Omar Din. Page 8... more This is a book on Cyberparenting by CyberSecurity Malaysia (CSM) and Dr. Meriam Omar Din. Page 8 and 9 were contributed by myself and my team. The book was launched on 24 February 2018 by Datin Paduka Seri Rosmah Mansor-our Prime Minister's wife, who is always concerned with well being of Malaysian Children and is the Patron to the PERMATA Programme. Launching of this book was done on a special day- to celebrate Safer Internet Day (SID 2018) The Malaysian Chapter. My team is in partnership with CSM and National Council of Women's Organisations (NCWO) Malaysia to empower women, parents and children to be #CyberSAFE. This year our work is focused towards building #CyberResilient Families.
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Papers by safinaz mohd khialdin
International Journal of Ophthalmology
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Frontiers in Cellular Neuroscience
PurposeThe aim of this study was to evaluate the choroidal and photoreceptor thickness in highly ... more PurposeThe aim of this study was to evaluate the choroidal and photoreceptor thickness in highly myopic eyes and its correlation with visual acuity.MethodsThis is a cross-sectional, observational study involving 57 eyes of 57 highly myopic subjects [spherical equivalent ≥ –6 diopters (D) or axial length ≥ 26 mm] seen in a tertiary institutional center. Eyes with any clinical evidence of maculopathy or amblyopia were excluded. All subjects underwent a refraction assessment, visual acuity, axial length measurement using the IOL Master, and full ocular assessment. Eyes were imaged using Spectralis Optical Coherence Tomography by one experienced operator. Two independent investigators manually measured subfoveal choroidal thickness (SFCT) and foveal photoreceptor thickness (FPT).ResultsThe mean SFCT was 195.88 ± 87.63 μm (range: 32–373) and mean FPT was 96.68 ± 11.23 μm (range: 67–100), after correction for ocular magnification. The best corrected visual acuity (BCVA) in LogMAR was nega...
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The wireless and ambulatory posture monitoring system monitors the movement and posture change of... more The wireless and ambulatory posture monitoring system monitors the movement and posture change of the human body with respect to the g-line. It is crucial to monitor the posture health of the ophthalmologist who spends a prolonged period on the static sitting posture while operating on the slit lamp which leads to any painful experience. The motivation of the proposed system is to improve the ergonomics of the ophthalmologist on their working environment and reduce any occupational potential hazard which may prompt Work-Related Musculoskeletal Disorders (WMSDs). The proposed system also induced a wireless system by using XBee wireless units to reduce the use of the wire that may tangle on the study subject which causes any uncomfortable experience to the study subject during the human trial. Inertial Measurement Unit (IMU) sensor which consists of an Accelerometer, a Gyroscope and a Magnetometer is used to measure the angle of deviation of the body segment with respect to the g-line...
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Translational Vision Science & Technology, 2022
Purpose To evaluate and compare biometric and optical coherence tomography parameters of ocular s... more Purpose To evaluate and compare biometric and optical coherence tomography parameters of ocular structures in preterm children without retinopathy of prematurity with term children. Methods A cross-sectional, comparative study was carried out from 2018 to 2019. In this study, 124 eyes of 62 preterm children were compared with 132 eyes of 66 term children aged between 7 and 9 years. Preterm children were born at 28 to 32 weeks with a birth weight of less than 2 kg with no ocular abnormalities, and term children were delivered at 37 or greater weeks and had a birth weight of 2 kg or more. All children had standardized eye examinations, and ocular measurements using the anterior and posterior segment optical coherence tomography and laser interferometry. Results Significant differences were found between the term and preterm children for horizontal corneal diameter: median, 12.2 mm (interquartile range [IQR], 0.4) versus median, 12.1 mm (IQR, 0.6; P < 0.005); axial length median, 23.03 mm (IQR, 1.10 mm) versus median, 22.88 mm (IQR, 1.35 mm; P = 0.017); global retinal nerve fiber layer thickness: mean ± standard deviation, 106.54 ± 10.23 µm versus mean ± standard deviation, 103.65 ± 10.178 µm (P = 0.024); temporal retinal nerve fiber layer thickness: median, 76 µm (IQR, 16 µm) vs median, 74 µm (IQR, 14 µm; P = 0.012); and the angle opening distance at 750 µm nasal: mean ± standard deviation, 0.815 ± 0.23 mm vs mean ± standard deviation, 0.749 ± 0.21 mm (P = 0.016). No significant differences were found for other anterior segment and angle parameters. Conclusions Preterm children with no retinopathy of prematurity have smaller eyes and thinner retinal nerve fiber layers than their term counterparts. The long-term effects of interrupted ocular growth in preterm children should be further studied into adulthood. Translational Relevance Preterm children maybe more predisposed to certain eye conditions because they have smaller eyes, and thus should be further monitored clinically.
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Asian Journal of Ophthalmology, 2019
Purpose: To describe the outcome of pediatric ptosis surgery using frontalis suspension technique... more Purpose: To describe the outcome of pediatric ptosis surgery using frontalis suspension technique. Design: Retrospective study. Methods: All patients with ptosis who underwent frontalis suspension from April 2009 to April 2014 at the Children’s Hospital at Westmead were included. Medical records of patients were reviewed and analyzed. Results: A total of 55 patients (74 primary procedures) were included in the study. Sixty-eight procedures (91.9%) used silicone as frontalis suspension material, three procedures used Gore-Tex, and three procedures used fascia lata. For procedures using silicone, the recurrence rate was 10.29%; 4.41% had infection and 1.47% had exposure keratopathy. All three procedures using Gore-Tex developed postoperative infection. No postoperative complication was documented in all the three procedures using fascia lata. Conclusion: A change in the practice from using banked fascia lata to silicone as frontalis suspension material is seen at the Children’s Hospit...
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A 68-year-old Malay male with no known medical illness presented with progressive growth of right... more A 68-year-old Malay male with no known medical illness presented with progressive growth of right conjunctival mass over a few months. Anterior segment examination of the right eye showed an inferior perilimbal elevated gelatinous conjunctival mass measuring 6 mm vertically x 14 mm horizontally with 360° corneal vascularisation. Excision biopsy and histopathological examination revealed areas of dysplastic cells involving the full epithelial thickness, suggestive of conjunctival intraepithelial neoplasia. The patient defaulted follow-up and presented later with recurrence involving the superior two-thirds of the cornea. Pulsed dosing of topical 5-fluorouracil 1% was initiated 4 times daily for a week with 21-day breaks for a total of 4 cycles. Regression of the lesion was noted after two cycles of 5-fluorouracil.
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Asian Journal of Ophthalmology, 2018
Purpose: To report a case series of seven eyes (six patients) with severe limbal stem cell failur... more Purpose: To report a case series of seven eyes (six patients) with severe limbal stem cell failure who underwent cultivated oral mucosa epithelium transplantation (COMET) in preparation for corneal transplant surgery and assess the change in visual acuity postoperatively. Design: Case series. Methods: A retrospective analysis of an interventional case series of six patients with severe limbal stem cell deficiency who underwent COMET between 2012 and 2015 was performed. Six eyes had COMET followed by corneal transplant, and one eye had corneal transplant preceding COMET. The change in the visual acuity after operation was evaluated. Results: A total of six patients with seven eyes were studied. All of them had severe ocular surface disease with limbal stem cell deficiency (LSCD) secondary to chemical injury (five eyes), SJS (one eye), and severe ocular rosacea (one eye). Four eyes had improvements in visual acuity, two of which achieved best corrected visual acuity (BCVA) of 6/12. Co...
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Cureus, 2021
The hazy corneal donor-recipient interface after corneal transplant may cause difficulties when i... more The hazy corneal donor-recipient interface after corneal transplant may cause difficulties when implanting the XEN gel stent via ab-interno approach. We aim to describe XEN gel stent implantation via ab-externo approach in refractory steroid-induced glaucoma after corneal lamellar keratoplasty. Under local anaesthesia, the XEN injector needle was inserted 7 mm behind the limbus with the bevel facing up, directly beneath the conjunctiva and advanced to the marked 2.5 mm scleral entry wound. The needle then pierced the sclera until the needle tip was just visible in the anterior chamber (AC). The slider was pushed until the tip of the XEN stent was seen in the AC. The needle was slowly withdrawn while still pushing the slider to complete stent deployment. Subconjunctival Mitomycin C 0.01% (30 µg/0.3 mL) was then injected posterior to the bleb. Three eyes of three patients with steroid-induced glaucoma after lamellar keratoplasty underwent XEN gel stent implantation via ab-externo appr...
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Cureus, 2021
The aim of this study is to report an unusual case of retinal racemose haemangioma (RRH) in a chi... more The aim of this study is to report an unusual case of retinal racemose haemangioma (RRH) in a child resulting in optic neuropathy and its optical coherence tomography angiography (OCT-A) findings. This is a retrospective case report. For almost a year, a 13-year-old girl experienced gradual, painless, generalized blurred vision in her right eye. Visual acuity was 6/60 with a positive relative afferent pupillary defect (RAPD) in her right eye. The right-eye fundus showed enlarged and tortuous retinal vessels extending from the optic disc to all four quadrants, including the juxta foveal region. OCT analysis revealed distortion in the region of enlarged vessels with minimal retinal fluid while OCT-A of the macula area demonstrated dilated and tortuous vessels in the superficial layers of the retina. Right intra-orbital vascular channels surrounding the optic nerve with optic nerve atrophy and gliosis were detected on magnetic resonance imaging angiography/venography (MRA/MRV). The cer...
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Malaysian Journal of Ophthalmology, 2019
Introduction: Vogt-Koyanagi-Harada (VKH) is an autoimmune disorder affecting melanocyte-containin... more Introduction: Vogt-Koyanagi-Harada (VKH) is an autoimmune disorder affecting melanocyte-containing tissues. Major histocompatibility complex, class II, DR beta1 (HLA-DRB1)*04 and its suballele HLA-DRB1*0405 were found to be associated with VKH in many studies.Purpose: To determine the association of HLA-DRB1*04 and its suballele HLADRB1*0405 with VKH patients of Malay descent.Materials and methods: A case control study was conducted among VKH patients of Malay ethnicity attending Ophthalmology Clinic, Hospital Selayang, Malaysia from December 2016 to December 2017. HLA-DRB1*04 allele-specific typing was performed on 14 Malay patients with VKH and 14 healthy controls using the polymerase chain reaction sequence-specific primer method. The data was then analysed using Fisher’s Exact test.Results: The frequency of HLA-DRB1*04 was noted to be higher in patients (42.9%) compared to controls (14.3%), but was not statistically significant (p = 0.209). The frequency of suballele HLA-DRB1*04...
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Malaysian Journal of Ophthalmology, 2019
This case series aims to discuss cases of bilateral optic neuritis secondary to presumed ocular t... more This case series aims to discuss cases of bilateral optic neuritis secondary to presumed ocular tuberculosis (TB) in two immunocompetent adults. Ocular TB has been associated with optic neuritis, but bilateral cases in immunocompetent individuals are rarely seen. We report a case series of two young healthy adults with bilateral painless optic neuritis as the presenting feature of ocular TB. Clinical examination, TB tests, and angiographic studies supported the diagnosis. All patients were started on anti-TB medication followed by oral prednisolone and had visual improvement a few weeks after treatment. As a conclusion, these cases highlight an atypical case of ocular TB presentation in immunocompetent individuals and thorough investigation is pertinent to preserve the visual function.
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Asian Journal of Ophthalmology, 2018
Background: Dacryocystorhinostomy (DCR) is the treatment of choice for nasolacrimal duct obstruct... more Background: Dacryocystorhinostomy (DCR) is the treatment of choice for nasolacrimal duct obstruction. Despite the emergence of new techniques such as endoscopic DCR, external DCR is still the criterion standard in primary cases. Aim: To analyse the epidemiological data, surgical technique, success rate, and complications of patients who underwent external DCR in Hospital Selayang from January 2015 to December 2016. Method: Retrospective case series. Results: A total of 21 eyes of 20 patients who underwent external DCR from January 2015 to December 2016 were identified and reviewed. There were 15 females (75%) and 5 males (25%). Age ranged from 5 to 75 years old, with a median age of 56 years old (IQR 23). Twelve patients presented with epiphora while eight patients presented with symptoms of dacryocystitis. One case was congenital, two were secondary nasolacrimal duct obstruction and the rest were primary nasolacrimal duct obstruction. All patients underwent external DCR under gener...
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Cureus, 2021
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Cureus, 2021
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Cureus, 2021
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Journal of Evolution of Medical and Dental Sciences, 2021
Retinoblastoma is the most common primary intraocular malignancy in children.1 Incidence of retin... more Retinoblastoma is the most common primary intraocular malignancy in children.1 Incidence of retinoblastoma is constant worldwide at one case per 15000–20000 live births, which corresponds to about 9000 new cases every year.2,3 It usually occurs in children under five years of age and can lead to loss of vision, and in extreme cases, death.4 The common signs of its presentation are leukocoria, strabismus, secondary glaucoma, proptosis, anterior chamber inflammatory signs and spontaneous hyphaema.1 Prognosis for vision and survival has significantly improved due to timely diagnosis and improved treatment methods.5
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Cureus, 2021
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Journal of Evolution of Medical and Dental Sciences, 2021
Endophthalmitis is a severe inflammatory disease classified as either endogenous or exogenous, de... more Endophthalmitis is a severe inflammatory disease classified as either endogenous or exogenous, depending on the route of infection. The disease may be caused by trauma, intraocular surgery, infectious keratitis or other endogenous causes.1,2 Endogenous endophthalmitis develops when the infectious agent travels via the bloodstream, crosses the blood ocular barrier and proliferates within the eye.3 Endogenous endophthalmitis accounts for approximately 5 – 8 % of all endophthalmitis cases.1 Specific predisposing factors may cause patients more at risk for rapid disease progression.3,4 Besides, source of the infection varies widely from the respiratory tract to urinary tract or liver abscess.5 We report a case series of endogenous endophthalmitis among immunocompromised patients. These cases highlighted the importance of early diagnosis with appropriate timely intervention to prevent further spread of infection and reduce the complications.
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Asian Journal of Ophthalmology, 1970
Phacolytic glaucoma normally presents with clinical features of eye pain and redness, anterior ch... more Phacolytic glaucoma normally presents with clinical features of eye pain and redness, anterior chamber inflammation, and increased intraocular pressure. This report is of a patient with phacolytic glaucoma, which presented as a total white hypopyon in a non-inflamed eye. Other possible causes of pseudohypopyon in this age group such as endogenous endophthalmitis or Masquerade syndrome were excluded before the patient underwent extracapsular cataract extraction with secondary posterior chamber intraocular lens implantation. She achieved satisfactory visual acuity postoperatively.
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