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Lesibana Peter

    Lesibana Peter

    BackgroundSexually transmitted infections continue to be a major health concern in sub-Saharan Africa where antimicrobial drugs are becoming ineffective due to increasing resistance. Many healthcare seekers in lower socio-economic... more
    BackgroundSexually transmitted infections continue to be a major health concern in sub-Saharan Africa where antimicrobial drugs are becoming ineffective due to increasing resistance. Many healthcare seekers in lower socio-economic settings depend on invasive alien plants administered by traditional health practitioners to treat sexually transmitted infections.MethodsRoots of selected plants were analysed for phytoconstituents using standard methods. Both the disc diffusion model and microdilution technique were used to determine the inhibition zone and minimum inhibitory concentration (MIC) of plant extracts against six clinical fungal strains and standard strain of Neisseria gonorrhoea. One-way ANOVA was used to find significant differences.ResultsDifferent phytoconstituents such as alkaloids, steroids, cardiac glycosides, terpenes, flavonoids, tannins and saponins were qualitatively detected, depending on plant species. Acetone extracted the highest number of phytoconstituents in ...
    BackgroundSexually transmitted infections continue to be a major health concern in sub-Saharan Africa where antimicrobial drugs are becoming ineffective due to increasing resistance. Many healthcare seekers in lower socio-economic... more
    BackgroundSexually transmitted infections continue to be a major health concern in sub-Saharan Africa where antimicrobial drugs are becoming ineffective due to increasing resistance. Many healthcare seekers in lower socio-economic settings depend on invasive alien plants administered by traditional health practitioners to treat sexually transmitted infections.MethodsRoots of selected plants were analysed for phytoconstituents using standard methods. Both the disc diffusion model and microdilution technique were used to determine the inhibition zone and minimum inhibitory concentration (MIC) of plant extracts against six clinical fungal strains and standard strain of Neisseria gonorrhoea. One-way ANOVA was used to find significant differences.ResultsDifferent phytoconstituents such as alkaloids, steroids, cardiac glycosides, terpenes, flavonoids, tannins and saponins were qualitatively detected, depending on plant species. Acetone extracted the highest number of phytoconstituents in ...
    Various indigenous cultures in the Limpopo Province of South Africa are transitioning from a traditional lifestyle to a westernised one. This leads to a loss of cultural identity and knowledge. Consequently, an ethnobotanical survey was... more
    Various indigenous cultures in the Limpopo Province of South Africa are transitioning from a traditional lifestyle to a westernised one. This leads to a loss of cultural identity and knowledge. Consequently, an ethnobotanical survey was conducted to investigate the medicinal uses of indigenous plants in the Mogalakwena Local Municipality of the Waterberg District in Limpopo Province, South Africa, an area experiencing rapid transition to a western lifestyle. The study interviewed 30 traditional healers via a semi-structured questionnaire. Thirty five indigenous plant species were documented to be used in the treatment of 37 ailments. These species are distributed among 22 families, of which Asteraceae (5 species), Fabaceae (4 species) and Hyacinthaceae (3 species) are the most prominent. The remaining families are represented by either a single or two species. Bark and roots accounted for 50% of the material used, followed by leaves (12%) and tuber (8%), amongst other. Preparation of remedies was mainly through decoctions (40%), followed by infusions (33.3%), paste (8.3%), and fumes through burning (6.7%). The high percentage of bark and roots use is an area of concern. Furthermore this study found many instances of unsustainable harvesting techniques. These issues need immediate attention for the long term conservation of a number of threatened species identified in this study.
    Research Interests:
    Background: Invasive alien plant species (IAPs) are plants that have migrated from one geographical region to non-native region either intentional or unintentional.The general view of IAPs in environment is regarded as destructive to the... more
    Background: Invasive alien plant species (IAPs) are plants that have migrated from one geographical region to non-native region either intentional or unintentional.The general view of IAPs in environment is regarded as destructive to the ecosystem and they pose threat to native vegetation and species. However, some of these IAPs are utilized by local inhabitants as a substitute for scarce indigenous plants. The aim of the study is to conduct ethnobotanical survey on medicinal usage of invasive plant species in Waterberg District, Limpopo Province, South Africa. Materials and methods: An ethnobotanical survey on invasive plant species was conducted to distinguish species used for the treatment of various ailments in the Waterberg, District in the area dominated by Bapedi traditional healers. About thirty Bapedi traditional healers (30) were randomly selected via the snowball method. A guided field work by traditional healers and a semi-structured questionnaire was used to gather information. The questionnaire was designed to gather information based on the local name of plants, plant parts used and methods of preparation which is administered by the traditional healers. Results: The study revealed that Schinus molle L., Catharanthus roseus (L.), Datura stramonium L., Opuntia stricta (Haw.) Haw., Opuntia ficus-indica, Sambucus canadensis L., Ricinus communis L., Melia azedarch L., Argemone ochroleuca and Eriobotrya japonica are used for treatment of various diseases such as chest complaint, blood purification, asthma, hypertension and infertility. The most plant parts that were used are 57.6% leaves, followed by 33.3% roots, and whole plant, seeds and bark at 3% each. Noticeably, most of these plants are cultivated (38%), followed by 28% that are common to the study area, 20% abundant, 12% wild, and 3% occasionally. Schinus molle is the most frequently used plant species for the treatment of various ailments in the study area. National Environmental Management Biodiversity Act (NEMBA) (10/2004) and Conservation of Agricultural Resource Act (CARA) were consulted to confirm the invaders status. Only eight plants (60%) are regulated by CARA (10/2004). Of 10 IAPs, 80% (8 species) are listed in both NEMBA and CARA legislation. Only 20% (2 species) are listed in NEMBA alone. Conclusion: Invasive alien plants are utilized by communities to combat various ailments in humans and these plants can help to reduce pressure on heavily harvested indigenous plant.
    Research Interests: