- Virology, Molecular virology, Bioinformatics, Computational and Systems Biology, Insect Biocontrol: Development of Biocontrol Agents for Pest Insects, Viral Phylogenetic and Evolution, Apoptosis; Antiviral mechanisms, RNA interferens, and 19 moreMolecular aspects of Virus-Host interaction: Metagenomics and Structural proteomics, Bioinformatics, Molecular Biology, Systematics (Taxonomy), Cell Biology, Proteomics, Applied microbiology, Environmental Microbiology (Biology), Extremophiles, Virus-Host Interactions, Education, Social Sciences, Biology, Science, Biochemistry, Molecular Biochemistry, Environmental microbiology, Microbial Ecology, and Mycology and Plant pathologyedit
- Biochemist, Virologist, Viral infection epigenomicsedit
Research Interests:
Research Interests:
Research Interests:
Abstract RNA viruses in insects are targets of an RNA interference (RNAi)-based antiviral immune response, in which viral replication intermediates or viral dsRNA genomes are processed by Dicer-2 (Dcr-2) into viral small interfering RNAs... more
Abstract RNA viruses in insects are targets of an RNA interference (RNAi)-based antiviral immune response, in which viral replication intermediates or viral dsRNA genomes are processed by Dicer-2 (Dcr-2) into viral small interfering RNAs (vsiRNAs). Whether dsDNA virus infections are controlled by the RNAi pathway remains to be determined. Here, we analyzed the role of RNAi in DNA virus infection using Drosophila melanogaster infected with Invertebrate iridescent virus 6 (IIV-6) as a model.
Background The competence of the tsetse fly Glossina pallidipes (Diptera; Glossinidae) to acquire salivary gland hypertrophy virus (SGHV), to support virus replication and successfully transmit the virus depends on complex interactions... more
Background The competence of the tsetse fly Glossina pallidipes (Diptera; Glossinidae) to acquire salivary gland hypertrophy virus (SGHV), to support virus replication and successfully transmit the virus depends on complex interactions between Glossina and SGHV macromolecules. Critical requisites to SGHV transmission are its replication and secretion of mature virions into the fly's salivary gland (SG) lumen.
Research Interests: Virology, Apoptosis, Gene Silencing, Biological Sciences, RNA interference, and 12 moreCell line, Animals, Programmed cell death, Viral Infection, Amino Acid Profile, Amino Acid Sequence, Open Reading Frame, Gene expression profiling, Iridovirus, Cydia pomonella, Transient Expression, and Molecular Sequence Data
Research Interests:
A cytoplasmic polyhedrosis virus (CPV) was isolated from the larvae of Thaumetopoea pityocampa and shown to cause an infection of midgut cells. This viral infection revealed several important diagnostic symptoms, including discoloration... more
A cytoplasmic polyhedrosis virus (CPV) was isolated from the larvae of Thaumetopoea pityocampa and shown to cause an infection of midgut cells. This viral infection revealed several important diagnostic symptoms, including discoloration of the posterior midgut, reduced feeding, and extended development time of the larvae. The virus infection is lethal to Thaumetopoea pityocampa, and with the increasing doses kills the larvae within 4-5 days post infection. Electron microscopy studies showed typical cytoplasmic polyhedral ...