Universitas Airlangga
Faculty of Pharmacy, Pharmaceutics Department
The aim of this research was to investigate the effect of two operating parameters (inlet temperature and pump speed) of laboratory spray dryer to optimize the production of ketoprofen-carboxymethyl chitosan (CM chitosan) microparticles... more
Chitosan, a cationic polysaccharide has many advantages as carrier for drug delivery system such as biocompatible, biodegradable and non toxic. Diterpen lacton fraction of sambiloto (Andrographis paniculata) has antimalarial activity but... more
The aim of this research was to investigate the effect of ketoprofen amount on drug content and drug release profile of kitosan microparticles of ketoprofen. Microparticles was prepared by orifice-ionic gelation method with... more
Microparticles of theophylline using chitosan as polymer and tripolyphosphate as crosslinker were prepared by ionic gelation (IG) methods. In this study, microparticles were prepared by two different of IG methods : orifice ionic gelation... more
Abstrak Diketahul bahwa daun sirih dari tanaman Piper betle Linn. telah lama digunakan dalam pengobatan tradisional untuk misalnya sebagai obat kumur dan pengobatan luka. Penggunaan sediaan gel antiseptik untuk tangan meningkat karena... more
Objectives: The aim of this study was to investigate crystallinity and compatibility transformation of two binary mixtures of analgesic substance with excipient due to mixing and compression. Methods: Analgesic substances used in this... more
Objective: The present study aims to prepare and characterize cocrystals of artesunate (AR) -nicotinamide (NI) in order to improve bioavailability and efficacy of artesunate as an antimalarial drug. Methods: Cocrystals were prepared using... more
- by Retno Sari
Objective: This paper was aimed to study the effect of chitosan, sodium tripolyphosphate (TPP) as crosslinker, and diterpene lactone fraction of sambiloto (FDTL) from Andrographis paniculata Nees which contained 75.9% andrographolide on... more
Objectives The study aimed to determine the effect of quercetin on the expression of primary regulator gene involved in lipogenesis and triglycerides synthesis in the liver, and the sterol regulatory binding protein-1c (SREBP-1c) mRNA in... more