Iranien history research by Reza Farnoud
l'Harmattan, 2024
La partie centrale du monde iranien est majoritairement désertique. Les autres régions similaires... more La partie centrale du monde iranien est majoritairement désertique. Les autres régions similaires sur la planète ont tendance à être laissées à l’abandon mais ici, depuis des millénaires, on cultive la terre et exporte différents produits agricoles. Par quel miracle cela est-il possible ?
La réponse vient de l’invention du qanât, une technique ingénieuse qui permet de récupérer l’eau disponible dans le sous-sol des piémonts et de la transporter jusqu’aux plaines où s’étendent les champs agricoles. On parle de « révolution qanâtienne » pour souligner son importance historique.
Ce livre s’intéresse donc au qanât et à son histoire dans le monde iranien. Après une description de la géographie de cette région ainsi que de ses particularités hydrologiques et agronomiques, sont expliqués les principes techniques du qanât, sa diversité et sa méthode de construction. Enfin, il aborde son utilisation par les paysans, ainsi que son impact sur leur organisation sociale, leur économie et leurs croyances.
قدیمی ترین غذاهای ایرانی, 2022
Over 150 iranian recipes extracted from the oldest sources. Additional informations about popul... more Over 150 iranian recipes extracted from the oldest sources. Additional informations about popular culinary practices in the early centuries of Islam.
بازنویسی بیش از 150 دستور غذا از قدیمی ترین منابع موجود به همراه توضیحاتی پیرامون آشپزی و غذاهای رایج در اولین قرون اسلامی
2022
پا به پای ناصر خسرو- جستارهایی در تاریخ اجتماعی ایران, 2014
پا به پای ناصر خسرو- جستارهایی در تاریخ اجتماعی ایران
خلاصه سفرنامه ناصر خسرو
بهمراه مجموعه مقا... more پا به پای ناصر خسرو- جستارهایی در تاریخ اجتماعی ایران
خلاصه سفرنامه ناصر خسرو
بهمراه مجموعه مقالاتی درباره تاریخ اجتماعی ایرانیان در هزار سال پیش
H and S
چاپ دوم
2014
.
اطلس تاریخی ایران در دوران ساسانی, 2016
اطلس تاریخی ایران در دوران ساسانی
نشر نی
تهران
1395
اطلس تاریخی ایران از ظهور اسلام تا دوران سلجوقی, 2012
اطلس تاریخی ایران از ظهور اسلام تا دوران سلجوقی
نشر نی
تهران
چاپ دوم
1390
Cardiovascular research by Reza Farnoud
Quality of life after transcatheter or surgical aortic valve replacement using the Toronto Aortic Stenosis Quality of Life Questionnaire, 2021
Background The Toronto Aortic Stenosis Quality of Life Questionnaire (TASQ) is a validated instru... more Background The Toronto Aortic Stenosis Quality of Life Questionnaire (TASQ) is a validated instrument for assessing quality of life (QoL) in patients with severe aortic stenosis (AS). In this study, we evaluated health status outcomes, based on the TASQ, in patients with severe AS undergoing transcatheter aortic valve replacement (TAVR) or surgical aortic valve replacement (SAVR). Methods The TASQ registry was a prospective observational registry. Patients with severe AS from nine centres in Europe and one in Canada underwent either SAVR or transfemoral TAVR. Patients completed the TASQ, Kansas City Cardiomyopathy Questionnaire and Short Form-12 V.2 prior to the intervention, predischarge, and at 30-day and 3-month follow-ups. Primary end point was the TASQ score. Results In both the TAVR (n=137) and SAVR (n=137) cohorts, significant increases were observed in all three scores. The overall TASQ score improved as did all but one of the individual domains at 3 months after the intervention (p<0.001). TASQ health expectations were the only domain which worsened (p<0.001). Across TASQ subscores, significant changes were evident from the time of discharge in the TAVR and 30-day follow-up in the SAVR cohort. In a categorical analysis of the TASQ, 39.7% of the TAVR group and 35.0% of the SAVR group had a substantially improved health status at 3 months compared with baseline. Conclusions The TASQ captured changes in QoL among patients with severe AS who were treated with TAVR or SAVR. QoL improved substantially after either intervention, as indicated by changes in the TASQ overall score at 3 months. Trial registration number NCT03186339.
Coronary Artery Disease, 2024
Background The prevalence and location of coronary artery disease (CAD) in anomalous aortic origi... more Background The prevalence and location of coronary artery disease (CAD) in anomalous aortic origin of a coronary artery (AAOCA) remain poorly documented in adults. We sought to assess the presence of CAD in proximal (or ectopic) and distal (or nonectopic) segments of AAOCA. We hypothesized that the representation of CAD may differ among the different courses of AAOCA. Methods The presence of CAD was analyzed on coronary angiography and/or coronary computed tomography angiography in 390 patients (median age 64 years; 73% male) with AAOCA included in the anomalous coronary arteries multicentric registry. Results AAOCA mainly involved circumflex artery (54.4%) and right coronary artery (RCA) (31.3%). All circumflex arteries had a retroaortic course; RCA mostly an interarterial course (98.4%). No CAD was found in the proximal segment of interarterial AAOCA, whereas 43.8% of retroaortic AAOCA, 28% of prepulmonic AAOCA and 20.8% subpulmonic AAOCA had CAD in their proximal segments (P < 0.001). CAD was more prevalent in proximal than in distal segments of retroaortic AAOCA (OR: 3.1, 95% CI: 1.8-5.4, P < 0.001). On multivariate analysis, a retroaortic course was associated with an increased prevalence of CAD in the proximal segment (adjusted OR 3.4, 95% CI: 1.3-10.7, P = 0.022). Conclusion Increased prevalence of CAD was found in the proximal segment of retroaortic AAOCA compared to the proximal segments of other AAOCA, whereas no CAD was observed in the proximal segment of interarterial AAOCA. The mechanisms underlying these differences are not yet clearly identified.
JACC cardiovascular imaging, 2020
Interarterial course of anomalous aortic origin of coronary artery (AAOCA) is the most frequent f... more Interarterial course of anomalous aortic origin of coronary artery (AAOCA) is the most frequent form found on autopsy of young patients who experienced sudden cardiac death. Patients dying of AAOCA often have an intramural coronary segment crossing the aortic wall with elliptic luminal narrowing (1). Fractional flow reserve-computed tomography (FFR-CT) imaging offers evaluation of the hemodynamic impact of coronary stenosis by modeling stress blood flow (2) and might represent an interesting imaging approach in AAOCA. Among 496 patients included in the observational multicentric Anomalous Connections of the Coronary Arteries (ANOCOR) registry (3), a total of 107 patients were imaged with a dedicated coronary CT angiog-raphy (CTA) protocol, but only 62 scans were deemed of sufficient image quality for FFR-CT analysis (se-vere motion artifacts in 14, image quality not sufficient in 29, and former coronary revascularization in 2). The ANOCOR registry has been approved by the Institutional Review Board of Bichat University Hospital (IRB00006477), and all patients have signed a consent form for the use of their clinical and imaging data for research purposes. Morphological analysis of coronary CTA scans included: 1) luminal surface narrowing; 2) luminal eccentricity; and 3) takeoff angle. Intramural path was defined by the presence of 3 morphological criteria: takeoff angle <30 , luminal surface narrowing >50%, and eccentricity degree >1.5. For FFR-CT measurements, coronary CTA data were transmitted to a central core laboratory (HeartFlow Inc., Redwood City, California). FFR-CT values were computed by selecting regions of interest proximally immediately at the end of the ectopic segment, defined as the point where AAOCA reaches its usual path and 3 cm after the ostium of non-AAOCA arteries, and in most distal segments of coronary arteries. To test the interobserver reproducibility, coronary CTA and FFR-CT analyses were performed by operators with long and only limited experience in AAOCA evaluation. Sixty-two patients (mean age 59.5 AE 12.8 years; 79% male) were included, with 63 AAOCA involving left main (n ¼10), right coronary (n ¼ 37), left anterior descending a (n ¼ 2), and left circumflex (n ¼ 14) arteries. AAOCA course was interarterial (n ¼ 37, including 9 with intramural path), retroaortic (n ¼ 17), retropulmonic (n ¼ 6), and pre-pulmonic (n ¼ 3). Distal FFR-CT values <0.80 were more prevalent in AAOCA with surface narrowing >50% (odds ratio [OR]: 4.2; 95% confidence interval [CI]: 1.3 to 13.7; p ¼ 0.01), eccentricity degree >1.5 (OR: 2.6; 95% CI: 0.8 to 8.4; p ¼ 0.11), angle <30 (OR: 3.5; 95% CI: 1.1 to 11.9; p ¼ 0.05), and with all 3 criteria of intramural path on coronary CTA (OR: 9.2; 95% CI: 1.7 to 49.9; p ¼ 0.01) but not specifically in AAOCA with inter-arterial course (OR: 1.2; 95% CI: 0.4 to 3.7; p ¼ 0.74). FFR-CT values calculated proximally and distally to the ectopic segment were significantly lower in interarterial AAOCA with all 3 versus fewer than the 3 morphological criteria of intramural path on coronary CTA (proximal FFR-CT values: 0.80 [0.74 to 0.88] vs. 0.96 [0.93 to 0.98]; distal FFR-CT values: 0.77 [0.54 to 0.80] vs. 0.86 [0.80 to 0.90], respectively [median and interquartile Q1 to Q3 range]; p < 0.05 with Wil-coxon tests) (Figure 1). A cutoff value of proximal FFR-CT #0.83 provided sensitivity of 96% and spec-ificity of 100% for identification of ANOCOR with intramural path on coronary CTA (area under the curve: 0.89). Interobserver agreement for defining acute takeoff angle, luminal narrowing >50%, or eccentricity degree >1.5 on coronary CTA were measured at 75% (K ¼ 0.40), 75% (K ¼ 0.45), and 84% (K ¼ 0.68), respectively. Agreement between expert and non-expert readers was 86% (K ¼ 0.45) for the identification of AAOCA with all 3 morphological criteria of intramural path, and at 98% (K ¼ 0.90) and 94% (K ¼ 0.84) for proximal and distal FFR-CT. The presence of intramural path of AAOCA can be observed during cardiac surgery but is difficult to identify with invasive or noninvasive imaging techniques. Morphological CT imaging criteria have been proposed empirically based on per-operative and forensic observations. An important limitation of these criteria is that they are based on cutoff values, which exhibit significant interobserver variability as shown by weak concordance rates observed between expert and non-expert observers. In contrast, FFR-CT offers a high agreement rate between expert and non-expert readers as a result of automated detection and analysis of coronary arteries. The threshold identified for AAOCA (FFR-CT #0.83) is higher than the usual 0.75 to 0.80 value J A C C : C A R D I O V A S C U L A R I M A G I N G
Archives of Cardiovascular Diseases Supplements, 2019
International Journal of Cardiology, Mar 1, 2012
Corresponding author at: Service d'Hématologie et Immunologie, Hôpital Bichat-Claude-Bernard... more Corresponding author at: Service d'Hématologie et Immunologie, Hôpital Bichat-Claude-Bernard, 46 rue Henri Huchard, 75877 Paris Cedex 18, France. Tel.: + 33 1 40 25 85 21; fax: + 33 1 40 25 88 53. ... Received 25 October 2011; received in revised form ...
The Lancet Neurology, 2012
The New England journal of medicine, Jan 3, 2011
Vitamin K antagonists have been shown to prevent stroke in patients with atrial fibrillation. How... more Vitamin K antagonists have been shown to prevent stroke in patients with atrial fibrillation. However, many patients are not suitable candidates for or are unwilling to receive vitamin K antagonist therapy, and these patients have a high risk of stroke. Apixaban, a novel factor Xa inhibitor, may be an alternative treatment for such patients.
European Heart Journal, 2009
Cancer research by Reza Farnoud
Journal of Cell Science, Sep 1, 1998
International Journal of Oncology, Sep 10, 2013
Clinical and …, 1997
... to produce internal acidification due to a typical vacuolar H+-ATPase [8,9,30]. It is therefo... more ... to produce internal acidification due to a typical vacuolar H+-ATPase [8,9,30]. It is therefore possible that the extracellular acidification produced by breast cancer cells in the absence ofglycolysis could be caused by increased leakage of protons from phagosomes, similar to that ...
Laboratory investigation; a journal of technical methods and pathology, 1994
Laminin (LM) is an integral component of basement membranes (BM), with important roles in various... more Laminin (LM) is an integral component of basement membranes (BM), with important roles in various aspects of cell biology. Several different isoforms of LM have been described, and each comprises a molecule consisting of three subunit polypeptides, the A, B1, B2, M or S chain. The distribution of different LM subunits was studied in human nontumoral anterior pituitaries obtained postmortem and in pituitary adenomas by immunocytochemical methods using specific monoclonal antibodies. In normal tissue, the A, B1, and B2 chains had a ubiquitous localization in both parenchymatous and vascular BMs and in the pericapillary connective tissue space also. The S chain seemed to have principally a vascular localization, in contrast to the M chain that was mostly localized in the parenchymatous BM. The same antigens were investigated in 23 human pituitary adenomas of different secretory type, grade and invasiveness. In all cases, the five monoclonal antibodies gave a positive staining. The pres...
Neuropeptides, Jun 1, 1994
Http Www Theses Fr, 1994
Pour mieux comprendre le developpement et la progression des adenomes hypophysaires humains, nous... more Pour mieux comprendre le developpement et la progression des adenomes hypophysaires humains, nous avons compare la structure et la composition du stroma adenomateux a celles du tissu conjonctif de l'antehypophyse humaine normale, ainsi que l'expression des recepteurs de la matrice extra-cellulaire au niveau des cellules normales et adenomateuses. Nos principaux resultats sont les suivants: (1) la formation et la progression des adenomes hypophysaires sont associees au developpement d'un stroma qui presente des alterations structurales remarquables par rapport au tissu conjonctif et a la vascularisation de la glande normale ; (2) les adenomes hypophysaires progressent a l'interieur du parenchyme normal par un processus actif qui impliquerait la desorganisation et la destruction du tissu conjonctif normal et la colonisation progressive des cordons juxta-tumoraux de cellules normales par les cellules adenomateuses ; (3) les changements phenotypiques de la vascularisation adenomateuse, par rapport au tissu normal, sont accompagnes d'une expression differentielle des isoformes de la laminine et de la fibronectine dans les vaisseaux tumoraux ; (4) en comparaison avec l'antehypophyse normale, les adenomes presentent des alterations profondes de l'expression des recepteurs aux composants de la matrice extra-cellulaire appartenant a la famille des integrines, aussi bien dans les cellules tumorales que dans les cellules du stroma
Uploads
Iranien history research by Reza Farnoud
La réponse vient de l’invention du qanât, une technique ingénieuse qui permet de récupérer l’eau disponible dans le sous-sol des piémonts et de la transporter jusqu’aux plaines où s’étendent les champs agricoles. On parle de « révolution qanâtienne » pour souligner son importance historique.
Ce livre s’intéresse donc au qanât et à son histoire dans le monde iranien. Après une description de la géographie de cette région ainsi que de ses particularités hydrologiques et agronomiques, sont expliqués les principes techniques du qanât, sa diversité et sa méthode de construction. Enfin, il aborde son utilisation par les paysans, ainsi que son impact sur leur organisation sociale, leur économie et leurs croyances.
بازنویسی بیش از 150 دستور غذا از قدیمی ترین منابع موجود به همراه توضیحاتی پیرامون آشپزی و غذاهای رایج در اولین قرون اسلامی
2022
خلاصه سفرنامه ناصر خسرو
بهمراه مجموعه مقالاتی درباره تاریخ اجتماعی ایرانیان در هزار سال پیش
H and S
چاپ دوم
2014
.
Cardiovascular research by Reza Farnoud
Cancer research by Reza Farnoud
La réponse vient de l’invention du qanât, une technique ingénieuse qui permet de récupérer l’eau disponible dans le sous-sol des piémonts et de la transporter jusqu’aux plaines où s’étendent les champs agricoles. On parle de « révolution qanâtienne » pour souligner son importance historique.
Ce livre s’intéresse donc au qanât et à son histoire dans le monde iranien. Après une description de la géographie de cette région ainsi que de ses particularités hydrologiques et agronomiques, sont expliqués les principes techniques du qanât, sa diversité et sa méthode de construction. Enfin, il aborde son utilisation par les paysans, ainsi que son impact sur leur organisation sociale, leur économie et leurs croyances.
بازنویسی بیش از 150 دستور غذا از قدیمی ترین منابع موجود به همراه توضیحاتی پیرامون آشپزی و غذاهای رایج در اولین قرون اسلامی
2022
خلاصه سفرنامه ناصر خسرو
بهمراه مجموعه مقالاتی درباره تاریخ اجتماعی ایرانیان در هزار سال پیش
H and S
چاپ دوم
2014
.