Azadeh Mirabedini
University of Wollongong, Chemistry, Graduate Student
Spinal cord injury (SCI) represents a significant health and social problem, and therefore it is vital to develop novel strategies that can specifically target it. In this context, the objective of the present work was to develop a new... more
Spinal cord injury (SCI) represents a significant health and social problem, and therefore it is vital to develop novel strategies that can specifically target it. In this context, the objective of the present work was to develop a new range of three-dimensional (3D) tubular structures aimed at inducing the regeneration within SCI sites. Up to six different 3D tubular structures were initially developed by rapid prototyping: 3D bioplotting-based on a biodegradable blend of starch. These structures were then further complemented by injecting Gellan Gum, a polysaccharide-based hydrogel, in the central area of structures. The mechanical properties of these structures were assessed using dynamic mechanical analysis, under both dry and wet conditions, and their morphologies/porosities were analyzed using micro-computed tomography and scanning electron microscopy. Biological evaluation was carried out to determine their cytotoxicity, using both minimum essential medium (MEM) extraction an...
Research Interests: Materials Engineering, Mechanical Engineering, Biomedical Engineering, Medicine, Rapid Prototyping, and 15 moreCell line, Cell morphology, Humans, Porosity, Animals, Male, Micro Computed Tomography, Rats, In vitro culture, Physiological Stress Markers, Gellan Gum, Materials Testing, Dynamic Mechanical Analysis, Biochemistry and cell biology, and Mechanical Property
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ABSTRACT One-step continuous wet-spinning of coaxial electroactive fibres of chitosan/graphene oxide (Chit/GO) via a facile method is introduced for the first time, eliminating the need for post-treatment processes. Spinnability of... more
ABSTRACT One-step continuous wet-spinning of coaxial electroactive fibres of chitosan/graphene oxide (Chit/GO) via a facile method is introduced for the first time, eliminating the need for post-treatment processes. Spinnability of coaxial fibres as well as their characterization for several properties is investigated. L-ascorbic acid was found to reduce graphene oxide under mild conditions to create conductivity in the final fibre. As-prepared fibres were found to be cytocompatible with good electrical conductivity and mechanical properties. SEM images from the cross-section of Chit/GO fibres showed an irregular shaped multifilament GO fibre covered with a cylinder-shaped sheath of chitosan. Coaxial fibres had an ultimate tensile stress and elastic modulus that increased 8 500% and 3 350%, respectively compared to the graphene oxide fibres alone.
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Tissue scaffolds can be synthesised from synthetic or biologically based bioresorbable polymers that act as a functional or inert framework for missing or malfunctioning human tissues and organs. The primary role of a scaffold is to... more
Tissue scaffolds can be synthesised from synthetic or biologically based bioresorbable polymers that act as a functional or inert framework for missing or malfunctioning human tissues and organs. The primary role of a scaffold is to provide a temporary substrate to which cells can adhere.
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Electrical stimulation has been able to provide beneficial effects for regeneration of tissue: muscle (Doucet et al. in Yale J Biol Med 85:201–215, 2012, [1]; Hsu et al. in Sensors 11:1932–1942, 2011, [2]; Longo et al. in Stem Cells Int... more
Electrical stimulation has been able to provide beneficial effects for regeneration of tissue: muscle (Doucet et al. in Yale J Biol Med 85:201–215, 2012, [1]; Hsu et al. in Sensors 11:1932–1942, 2011, [2]; Longo et al. in Stem Cells Int 2012:175038, 2012, [3]; Meng et al. in Applied biomedical engineering. pp. 37–62, 2011, [4]), nerve (Rupp et al. in J Neurosci Methods 166:266–277, 2007, [5]; Wei in Science 1373:1372–1376, 2014, [6]) and bone (Choa et al. in Eur Cell Mater 6:72–85, 2003, [7]). A range of metallic electrodes, most commonly Pt or Ti based, have conventionally been used (Meng et al. in Applied biomedical engineering. pp. 37–62, 2011, [4]; Lafayette in Anal Biomed Eng 31:879–890, 2003, [8]). More recently the use of organic conductors has attracted attention since they can be loaded with bioactivity enhancing the electro-cellular communication process (Ben-jacob and Hanein in J Mater Chem 18:5181–5186, 2008, [9]; Wallace et al. Organic bionics. p 240, 2012, [10]).
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Abstract In this study, the electromechanical properties and strain monitoring behavior of graphene-coated glass fiber reinforced epoxy (GGFRE) composites were investigated. Glass fabrics were first coated with 2 wt% graphene dispersions... more
Abstract In this study, the electromechanical properties and strain monitoring behavior of graphene-coated glass fiber reinforced epoxy (GGFRE) composites were investigated. Glass fabrics were first coated with 2 wt% graphene dispersions using a blade coating method and composites of these graphene-coated glass fabrics were manufactured using vacuum resin infusion. As-prepared GGFRE showed an increase in normalized resistance (ΔR/R0) by 4.46%, 10.5%, 11.07% and 11.27% proportional to the applied cyclic tensile forces up to 2000N, 3000N, 4000N and 5000N, respectively. The corresponding gauge factors were calculated to be 14.56 ± 1, 13.32 ± 1, 11.23 ± 0.5 and 8.69 ± 2, respectively. It was also observed that under cyclic tensile loadings at 2000N, ΔR/R0 values were consistent within 11 cycles indicating a reliable sensing performance. The integration of graphene into the composite has shown to decrease the tensile strength as well as flexural strength and flexural modulus by 26%, 37% and 39%, respectively. This drop is believed to be caused by the lower fiber volume content in the GGFRE compared to that of the neat glass fiber composite and the ineffective interfacial interaction between the glass fiber and the graphene dispersion. The piezo-resistive behavior indicated by GGFRE along with their scalable manufacturing method suggest them as promising potential candidates for strain sensing applications.
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Technological improvements in the development of smaller and lighter smart multi-functional structures have enabled the fabrication of many miniaturized portable electronic devices in recent years. The integration of these... more
Technological improvements in the development of smaller and lighter smart multi-functional structures have enabled the fabrication of many miniaturized portable electronic devices in recent years. The integration of these organo-electronic components into common textile structures could facilitate free and easy access while allowing a number of smart functionalities such as signalling, sensing, actuating, energy storage or information processing.
The ubiquity of wearables, coupled with the increasing demand for power, presents a unique opportunity for nanostructured fiber-based mobile energy storage systems. When designing wearable electronic textiles, there is a need for... more
The ubiquity of wearables, coupled with the increasing demand for power, presents a unique opportunity for nanostructured fiber-based mobile energy storage systems. When designing wearable electronic textiles, there is a need for mechanically flexible, low-cost and light-weight components. To meet this demand, we have developed an all-in-one fiber supercapacitor with a total thickness of less than 100 μm using a novel facile coaxial wet-spinning approach followed by a fiber wrapping step. The formed triaxial fiber nanostructure consisted of an inner poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) core coated with an ionically conducting chitosan sheath, subsequently wrapped with a carbon nanotube (CNT) fiber. The resulting supercapacitor is highly flexible, delivers a maximum energy density 5.83 Wh kg−1 and an extremely high power of 1399 W kg−1 along with remarkable cyclic stability and specific capacitance. This asymmetric all-in-one fiber supercapacitor may pav...
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Currently, there is no incentive to buy airline tickets until the end of the game. Were the price of flights to tend to increase, or were supply limited, agents would have to balance the advantage of keeping their options open against the... more
Currently, there is no incentive to buy airline tickets until the end of the game. Were the price of flights to tend to increase, or were supply limited, agents would have to balance the advantage of keeping their options open against the savings of committing to travel packages earlier 6.
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Correction for ‘Developments in conducting polymer fibres: from established spinning methods toward advanced applications’ by Azadeh Mirabedini et al., RSC Adv., 2016, 6, 44687–44716.
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This review provides a comprehensive picture of the history and latest developments in the field of conducting polymer fibres as well as their current/future applications.
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... More recently, Polito (2005) has usefully compared Egan's ideas with Vico's and Dewey's “philosophical anthropologies,” but her treatment stops short of an educational critique. ... 3rd ed. New York and Toronto:... more
... More recently, Polito (2005) has usefully compared Egan's ideas with Vico's and Dewey's “philosophical anthropologies,” but her treatment stops short of an educational critique. ... 3rd ed. New York and Toronto: Macmillan, 1994. Fettes, Mark. 2008. ...
ABSTRACT Surface passivation of AZNd Mg alloy with Pr(NO3)3 is studied using scanning electrochemical microscopy (SECM) in surface generation/tip collection (SG/TC) and AC modes. Corrosion protection afforded by the Pr treatment and the... more
ABSTRACT Surface passivation of AZNd Mg alloy with Pr(NO3)3 is studied using scanning electrochemical microscopy (SECM) in surface generation/tip collection (SG/TC) and AC modes. Corrosion protection afforded by the Pr treatment and the degradation mechanism in a simulated biological environment was examined on a local scale and compared with non-treated AZNd. SG/TC mode results revealed a drastic decrease in H2 evolution due to the Pr treatment. Mapping the local insulating characteristics using AC-SECM showed higher conductivity of the surface where H2 evolution was most favorable.