Mutasi pertukaran antara Proline kepada Alanin di kodon 12 gen Peroxisome Proliferator Activated Receptor Gamma (Pro12Ala PPARγ) adalah salah satu daripada faktor genetik utama yang menyumbang kepada tenaga yang berlebihan dan... more
Mutasi pertukaran antara Proline kepada Alanin di kodon 12 gen Peroxisome Proliferator Activated Receptor Gamma (Pro12Ala PPARγ) adalah salah satu daripada faktor genetik utama yang menyumbang kepada tenaga yang berlebihan dan mengakibatkan obesiti. Oleh itu, antara objektif kajian ini adalah untuk menentukan hubungkait antara variasi Pro12Ala pada gen PPARγ dan indeks jisim badan dalam kalangan kanak-kanak Melayu, menentukan perbezaan aktiviti fizikal antara subjek yang mempunyai mutasi gen dan tidak mempunyai mutasi Pro12Ala pada gen PPARγ dan menentukan perbezaan pengambilan lemak antara subjek yang mempunyai mutasi gen dan tidak mempunyai mutasi Pro12Ala pada gen PPARγ. The missense mutation of Proline to Alanine at codon 12 (Pro12Ala) of Peroxisome Proliferator Activated Receptor Gamma (PPARγ) is one of the most critical genetic factors predisposing to positive energy balance that may lead to development of obesity. Hence, the objectives of this study are to determine the assoc...
Introduction: Stigmatization towards cancer is a barrier to early cancer screening and treatment. This study was conducted to determine the level of cancer stigma among Malaysian university students in Malaysia with different... more
Introduction: Stigmatization towards cancer is a barrier to early cancer screening and treatment. This study was conducted to determine the level of cancer stigma among Malaysian university students in Malaysia with different sociodemographic backgrounds.Methods: This cross-sectional study recruited 400 students (mean age, SD = 22.22 ± 1.67 years) from a selected university in Malaysia. Data were collected from October 2019 to February 2020 through an online survey. The Cancer Stigma Scale (CASS) was used in assessing the levels of cancer stigma among university students with different courses and social backgrounds. The CASS was used in assessing multiple aspects of cancer stigma, including severity, personal responsibility, awkwardness, avoidance, policy opposition, and financial discrimination.Results: Data were analyzed using SPSS (version 23). Results showed that the stigmatization level toward cancer among university students varied across the six subscales. Items regarding th...
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Introduction: The Pro12Ala variant of the Peroxisome Proliferator Activated Receptor Gamma (PPARγ) is one of the critical genetic factor predispose to positive energy balance leading to obesity. Objective: This study aimed to determine... more
Introduction: The Pro12Ala variant of the Peroxisome Proliferator Activated Receptor Gamma (PPARγ) is one of the critical genetic factor predispose to positive energy balance leading to obesity. Objective: This study aimed to determine the association between Pro12Ala variant in the PPARγ gene with body mass indexs (BMI) status, physical activity and fat intake among Malay children. Methods: A total of 119 subjects aged between 9-11 years old from primary school in Kota Bharu, Kelantan were recruited. Anthropometric measurements were taken and activity counts of the subjects were recorded using accelerometer (Actigraph GT3X+). A food diary was distributed to all subjects to collect the data of the fat intake. Genotyping was performed using High Resolution Melting (HRM) analysis. Data obtained were analyzed using SPSS version 19. Results: There was a significant association between Pro12Ala variant in the PPARγ gene with BMI status. The allelic frequency of wildtype (Ala/ala) and het...
Orthorexia Nervosa (ON) is the obsession of an individual towards healthy foods. It has been shown to be related to quality of life (QoL). The aims of this study are to assess the prevalence of ON, QoL, and the correlation between ON and... more
Orthorexia Nervosa (ON) is the obsession of an individual towards healthy foods. It has been shown to be related to quality of life (QoL). The aims of this study are to assess the prevalence of ON, QoL, and the correlation between ON and QoL. 138 students completed Orto-15 and WHOQOL-BREF questionnaires. 67.4% of the students had the tendency to experience ON. For Quality of Life, the psychological domain scored the highest (M=64.14, SD=11.74), while the social domain was the lowest (M=62.52, SD=11.41). There was a small correlation (r<0.29) between Orthorexia Nervosa and the quality of life.
Introduction: Stigmatization towards cancer is a barrier to early cancer screening and treatment. This study was conducted to determine the level of cancer stigma among Malaysian university students in Malaysia with different... more
Introduction: Stigmatization towards cancer is a barrier to early cancer screening and treatment. This study was conducted to determine the level of cancer stigma among Malaysian university students in Malaysia with different sociodemographic backgrounds. Methods: This cross-sectional study recruited 400 students (mean age, SD = 22.22 ± 1.67 years) from a selected university in Malaysia. Data were collected from October 2019 to February 2020 through an online survey. The Cancer Stigma Scale (CASS) was used in assessing the levels of cancer stigma among university students with different courses and social backgrounds. The CASS was used in assessing multiple aspects of cancer stigma, including severity, personal responsibility, awkwardness, avoidance, policy opposition, and financial discrimination. Results: Data were analyzed using SPSS (version 23). Results showed that the stigmatization level toward cancer among university students varied across the six subscales. Items regarding the severity of a cancer diagnosis showed the highest level of agreement (32-52%; M = 3.05, SD = 0.96), whereas the item 'avoiding someone with cancer' showed the lowest agreement, 7-10% (Mean = 1.85, SD = 0.97). Stigma was significantly higher in young students, males, non-health science students, students in the junior year level, students without family histories of cancer, and the low-income group (p < 0.05). Conclusion: These findings may provide a benchmark of stigmatization level among university students in Malaysia and may be a valuable basis for delivering information and education on cancer screening and treatment.