TACSTD2

Tumor-associated calcium signal transducer 2 is a protein that in humans is encoded by the TACSTD2 gene.

This intronless gene encodes a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor.

Mutations of this gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.

This antigen is the target of the antibody-drug conjugate Sacituzumab govitecan.

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Further reading

EGP-6

The EGP-6 reactors are a scaled down version of the RBMK reactor design. Notably, these reactors along with the RBMK designs are some of the few active reactors which still use ordinary (light) water cooled graphite as a neutron moderator.

The only operating reactors of this type exist at the Bilibino Nuclear Power Plant, commissioned in 1974. The plant design was developed by the Ural Division of Teploelektroproekt together with Izhorskiye Zavody and FEI in Obninsk.

It is the world's smallest commercial nuclear reactor.

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EGP

EGP may refer to:

Organizations

Space