HLA-A34
HLA-A34 (A34) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α34 subset of HLA-A α-chains. For A34, the alpha "A" chain are encoded by the HLA-A*34 allele group and the β-chain are encoded by B2M locus. A34 and A*34 are almost synonymous in meaning. A34 is a split antigen of the broad antigen serotype A10. A34 is a sister serotype of A25, A26, A43, and A66.
A34 is most similar to A66..
Serotype
A34 serotyping is modest..
A34 allele frequencies
A*3401
A*3401 when found outside of Africa is primarily found in the South Asia, Austronesia and the South/Central part of the West Pacific Rim (WPR). It appears to have made it to Eastern Taiwan's indigenous tribes (Ami, Yami) but not more north of this region. It has not been detected in any sampling of Japan. Over most of the East Pacific Rim region where it is found it is limited to 1 or 2 common haplotypes in strong linkage disequilibrium. This indicates its presence in the WPR region is the result of recent migrations.
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