up; biopsy at the initial visit to confirm the diagnosis and more frequent control biopsies during clinical follow up to assess histological changes that may represent dysplasia. As a lesion at risk malignant transformation, OLP also needs to be confirmed by use of genetic markers. Helicobacter pylori on oral mucosa - topographic distribution Mravak-StipetiÊ M1, Gall-Troπelj K2, PaveliÊ J.2 1Department of Oral Medicine, School of Dental Medicine University of Zagreb, Zagreb, Croatia 2Ruer BoπkoviÊ Institute, Division of Molecular Medicine, Zagreb, Croatia Helicobacter pylori na oralnoj sluznici - topografska distribucija M1, K2, The purpose of this study was to examine the topographic distribution of Helicobacter pylori on oral mucosa in various oral lesions such as inflammation, oral ulceration, keratosis, candidiasis and burning mouth syndrome in comparison with healthy oral mucosa. J.2 Mravak-StipetiÊ Gall-Troπelj PaveliÊ 1Zavod za Oralnu Medicinu Stomatoloπkog fakulteta SveuËiliπta u Zagrebu, Zagreb, Hrvatska 2Institut Ruer BoπkoviÊ, Zavod za Molekularnu Medicinu, Zagreb, Hrvatska We applied nested PCR on cytologic specimens collected from 9 topographic sites of the healthy oral mucosa and from various oral lesions. Svrha rada bila je ispitati topografsku distribuciju bakterije Helicobacter pylori na oralnoj sluznici u upalnim, ulceroznim i keratotiËnim lezijama, kandidijazi i sindromu peËenja usta i usporediti s nalazom na zdravoj sluznici. Of a total 426 patients 66 (15.49 %) were positive for H. pylori,with no predilection for sex but with higher frequency in older patients, and with almost equal distribution on all examined topographic sites of the oral mucosa. H. pylori was detected in all examined diseases, except in candidiasis, with prevalence on tongue mucosa and in ulcerous lesions although without significant differences between lesions and healthy oral mucosa (p = 0.059). Primijenili smo nested PCR na citoloπkim uzorcima uzetim s 9 topografski razliËitih mjesta oralne sluznice i s razliËitih oralnih lezija. Od ukupno 426 ispitanika njih 66 (15,49 %) imalo je pozitivan nalaz H. pylori na oralnoj sluznici, bez predilekcije po spolu, ali s veÊom ËestoÊom nalaza u starijih ispitanika u usporedbi s mlaima te gotovo jednakom distribucijom na svim ispitanim topografskim stranama oralne sluznice. H. pylori otkriven je u svim ispitanim lezijama i sindromu peËenja usta osim u kandidijazi s veÊom prevalencijom na sluznici dorzuma jezika i u ulceroznim lezijama, premda bez statistiËki znatne razlike izmeu lezija i zdrave sluznice (p = 0,059). H.pylori is non-pathogenic for oral mucosa since it colonizes almost with the same frequency healthy and diseased oral mucosa. There is no preferential oral site or lesion for colonization of H. pylori. Utjecaj bruksizma na Ëeljusne kretnje H. pylori nije patogen za oralnu sluznicu jer kolonizira gotovo s istom ËestoÊom zdravu i oboljelu oralnu sluznicu. Takoer ne postoje preferirana mjesta na oralnoj sluznici za naseljavanje H. pylori. MuhviÊ-Urek M, UhaË I, KovaË Z, ©imunoviÊ-©oπkiÊ M, AntoniÊ R, BorËiÊ J. Medicinski fakultet, Studij stomatologije, Rijeka, Hrvatska Etiologija temporomandibularnih poremeÊaja (TMD) joπ je uvijek nerazjeπnjena. MoguÊi utjecaj bruksizma predmet je mnogih rasprava. Svrha ovog istraæivanja bila je odrediti uËinak bruksizma na funkciju stomatognatoga sustava. Ispitivana se skupina sastojala od 46 bruksista u dobi od 24-52 godine (x = 35,03 ± 6,92). Kontrolnu skupinu 364 ASC Acta Stomatol Croat, Vol. 37, br. 3, 2003.