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Chemistry of Heterocyclic Compounds
?ene? Adducts of N-substituted triazolinediones. 3. Synthesis of novel types of imidourazoles from N-substituted cis-cyclohex-4-ene-1,2-dicarboximides1990 •
Journal of Molecular Structure
Formation of 2,4,5-triaryl-4,5-dihydro-1 H-imidazoles, ( 1), from aryl aldehydes. Crystal structures of cis-( 1: aryl = pyridin-2-yl), { trans-[( 1: aryl = pyridin-2-yl)H] +[OAc] −·3H 2O}, { cis-[ 1: aryl = thien-2-yl]·0.5H 2O} and trans-( 1: aryl = thien-2-yl2007 •
2019 •
1997 •
Abstract: Selective alkylation and cyanoethylation of 2H(methyl) benzimidazoles (1, 2), benzimidazolin-2-one (3) and -2-thione (4), benzothiazolin-2-thione (5) and 2-methyl-benzopyrimidin-4-one (6, 2-methylquinazolin-4-one) have been studied. It was found that in the case of alkylation of 2H(methyl)benzimidazoles and benzimidazolin-2-thione by aliphatic halogen carboxylic acid esters and / or amides reaction leads to the formation of selectively N3- and S-alkyl derivatives. Interaction of benzothiazolin-2-thione and 2-methyl-benzopyrimidin-4-one with acrylonitrile takes place mono-cyanoethylation, but in the case of benzimidazolin-2-one takes place di-cyanoethylation reaction. It was revealed that formation of mono- and / or di-substituted products 7-13 dependence on the structure of starting compounds and the reaction conditions (reaction temperature and time, ratio of reagents). It should be noted that the obtained compounds are important synthons for further investigations. The structure of synthesized compounds (7-13) was confirmed by IR- and 1H NMR-spectroscopy.
Chemistry of Heterocyclic Compounds
Heterocycles with a bridging nitrogen atom. 15. The novel recyclization of dipyrido[1,2-a:1′,2′-c]-imidazolium salts to pyrido[1,2-a]-benzimidazole-8-carboxaldehydes2005 •
Quarterly Journal of Applied Chemical Research
Three Component Syntheses of Pyrrolo Imidazole Derivatives in the Presence of N-Methyl Imidazole, Activated Acetylenes and Phenylsulfonylacetophenone2015 •
Because of the significant role in biological processes in living cells and the diverse types of physiological activities, heterocyclic compounds are in focus of intense investigations by academic, industry and applied-oriented chemists. Considerably, ascientific renaissance of heterocycles during the last decades is closely related to the development of multicomponent approaches to their synthesis. Multicomponent methodology is fundamentally different from two-component or sequential processestogether with other innovative synthetic methods like microwave- and ultrasonic assisted reactions offer some new possibilities in constructing heterocyclic systems with high level of molecular diversity and complexity. Among them Imidazoles are quite important reagents in modern heterocyclic chemistry, and their reactions with electrophiles are the most widespread and facile synthetic approach for obtaining diverse heterocyclic systems containing Imidazolemoiety. An interest on these heterocy...
Monatshefte fur chemie
The pseudo-Michael reaction of 1-aryl-4,5-dihydro-1H-imidazol-2-amines with ethyl ethoxymethylenecyanoacetateThe pseudo-Michael reaction of 1-aryl-4,5-dihydro-1H-imidazol-2-amines with ethyl 2-cyano-3-methoxyprop-2-enoate (ethyl ethoxymethylenecyanoacetate) is investigated. At -10 °C reaction takes place on the exocyclic nitrogen atom, giving exclusively ethyl esters of 2-cyano-3-[(1-phenyl-4,5-dihydro-1H-imidazol-2-yl)amino]prop-2-enoic acid. The formation of isomeric enamines which may be a theoretical product of the reaction on N3 ring nitrogen atom is not observed. The N6 enamines, heated in boiling acetic acid, yield cyclic 1-aryl-5-oxo-2,3-dihydroimidazo[1,2-a]pyrimidine-6-carbonitriles. Heating of the enamines to the temperature of 120-140 °C without a solvent makes it possible to obtain a mixture of 1-aryl-5-oxo-2,3-dihydroimidazo[1,2-a]pyrimidine-6-carbonitriles and ethyl 1-aryl-5-imino-2,3-dihydroimidazo[1,2-a]pyrimidine-6-carboxylates. The reaction of the respective hydrobromides of 1-aryl-4,5-dihydro-1H-imidazol-2-amines with ethyl ethoxymethylenecyanoacetate in the presence of...
Infectious Diseases and Clinical Microbiology
Lessons from the Crimean War: How Hospital Design was Moulded by Nightingale and Others2019 •
Acta Biologica Sibirica
Duchesnea Indica (Andrews) Teschem. (Rosaceae JUSS.) – New Adventive Species to the Flora of the Republic of Uzbekistan2016 •
Prace Naukowe Uniwersytetu Ekonomicznego we Wrocławiu
Expected and achieved outcomes of child-related tax benefits in Germany2020 •
Sen'i Gakkaishi
Effect of Solvent Treatment on the Dyeing Rate of Wool Fiber1986 •
Studia Universitatis Babes-bolyai Chemia
Enhancement of physical properties in ZrO<sub>2</sub>/Ga<sub>2</sub>O<sub>3</sub> co-substituted indium oxide2017 •
Nature Photonics
Selective carrier injection into patterned arrays of pyramidal quantum dots for entangled photon light-emitting diodes2016 •
Headache Medicine
Migrânea e comportamento suicida: cronificação como mecanismo intermediário e associação com depressão e sintomas cognitivo-comportamentais no ataque2021 •
Morbidity and Mortality Weekly Report
Progress Toward Poliomyelitis Eradication — Nigeria, January 2014–July 20152015 •
5 April 2022, "The World as a City. A Philosophical Image between Greco-Roman Polytheism, Judaism, Christianity and Islam"
Macrocosm and Microcosm in Maimonides’ Guide