Comparison of the Effect of Exercise Type on the Prognosis Scores in Patients with Acute Ischemic Stroke

The Israel Medical Association journal: IMAJ

Trials, 2014

BMJ

ObjectiveTo determine the safety and efficacy of aerobic exercise on activities of daily living in the subacute phase after stroke.DesignMulticentre, randomised controlled, endpoint blinded trial.SettingSeven inpatient rehabilitation sites in Germany (2013-17).Participants200 adults with subacute stroke (days 5-45 after stroke) with a median National Institutes of Health stroke scale (NIHSS, range 0-42 points, higher values indicating more severe strokes) score of 8 (interquartile range 5-12) were randomly assigned (1:1) to aerobic physical fitness training (n=105) or relaxation sessions (n=95, control group) in addition to standard care.InterventionParticipants received either aerobic, bodyweight supported, treadmill based physical fitness training or relaxation sessions, each for 25 minutes, five times weekly for four weeks, in addition to standard rehabilitation therapy. Investigators and endpoint assessors were masked to treatment assignment.Main outcome measuresThe primary outc...

2012

Frontiers in Neurology

Archives of physical medicine and rehabilitation, 2016

To examine the effects of 12 weeks of twice-weekly intensive aerobic exercise on physical function and quality of life after subacute stroke. Randomized controlled trial. Ambulatory care. Fifty-six patients (28 women) aged ≥50 years who had a mild stroke (98% ischemic) and were discharged to independent living and enrolled 20 days (median) after stroke onset. Sixty minutes of group aerobic exercise, including 2 × 8 minutes of exercise with intensity up to exertion level 14-15/20 on the Borg rating of perceived exertion scale, twice weekly for 12 weeks (n=29). Controls (n=27) received no organized rehabilitation or scheduled physical exercise. Primary outcome measures: Aerobic capacity: Standard ergometer exercise stress test (peak work rate (WR)). Walking distance: 6-Minute Walk Test (6MWT). Secondary outcomes measures: Maximum Walking Speed 10 meters (MWS10m). Balance: Timed Up and Go (TUG), Single Leg Stance (SLS). Health-related quality of life: Euroqol-5D (EQ-5D). Participation ...

BMJ, 2009

Stroke induces changes in the haematological variables of post-stroke patients. Pathological changes in haematological variables can be reversed using aerobic exercise. This study assessed and compared the effects of Interval Training (IT), Continuous Training (CT) and a Combination of Interval and Continuous Training (CICT) modes of aerobic exercise on selected haematological variables of stroke survivors (SSv). Sixty-nine consecutively recruited SSv participated in this single blind randomized controlled trial. They were randomly assigned into one of the IT (n=25), CT (n=21) and CICT (n=23) groups. All the participants underwent aerobic training at 40-70% of heart rate reserve using a bicycle ergometer for eight consecutive weeks following the American Heart Association/American Stroke Association protocol. White blood cell count (WBC), red blood count (RBC), haemoglobin concentration (Hg), platelet count (PC) and mean platelet volume (MPV) were determined using PROCAN PE-6800. Data was analysed using descriptive statistics, one-way ANOVA, ANCOVA and paired t-test at " 0.05. No significant difference was observed in all the baseline variables across the three groups (p>0.05). All the pre-and post-intervention haematological variables were significantly different in all the groups (p<0.05) except WBC in the CT group (t=-0.538, p=0.596). Post-intervention WBC (5.71±1.31) were significantly different across the IT, CT and CICT groups respectively. The IT was the most effective in decreasing WBC and MPV and also the most effective in increasing Hg and PC. The IT, CT and CICT modes are effective in significantly improving the haematological variables of stroke survivors after eight weeks of aerobic training, the IT mode is, however, the most effective.

Journal of Exercise Rehabilitation

2010