Egptian Essential Drug List 2012-2013 1. ANAESTHETICS 1.1 General anesthetics and oxygen 1.1.1 Inhalational medicines 1 halothane 2 isoflurane 3 nitrous oxide 4 oxygen 1.1.2 Injectable medicines 5 Thiopentone Sodium 6 ketamine 7 propofol 1.2 Local anesthetics Inhalation.(liquid) Inhalation.(liquid) Inhalation.(cylinder) Inhalation (medicinal gas). Injection: 0.5 ,1 gm injection Injection: 50 mg/ml Injection: 10 mg/ml; 20 mg/ml. bupivacaine Injection: 0.25% ; 0.5% Injection for spinal anesthesia: 0.5% (hydrochloride) in 4?ml ampoule to be mixed with 7.5% glucose solution 9 lidocaine Injection: 2% Gel: 2% Ointment: 5% Cream: 5% Oral gel: 2,2.5 % 10 lidocaine + epinephrine (adrenaline) Injection: 2% + epinephrine 5mcg/ml 8 11 ephedrine Injection: 30 mg/ml 1.3 Preoperative medication and sedation for short-term procedures 12 atropine Injection: 1mg/1ml 13 midazolam Injection: 5mg/ml Injection: 10mg; 20mg 14 morphine Tablet: 30mg 2. ANALGESICS, ANTIPYRETICS, NON-STEROIDAL ANTI-INFLAMMATORY MEDICINES (NSAIMs), MEDICINES USED TO TREAT GOUT AND DISEASE MODIFYING AGENTS IN RHEUMATOID DISORDERS (DMARDs 2.1 Non-opioids and non-steroidal anti-inflammatory medicines (NSAIMs) 15 16 ibuprofen paracetamol 17 acetylsalicylic acid 2.2 Opioid analgesics 18 Fentanyl 19 Pethidine 20 Tramadol 21 morphine Tablet: 200mg; 400mg Suspension:100mg/5ml Suppository: 100mg; 30mg; 500mg Oral liquid: 120mg/5 ml Tablet: 500 mg Injection: 1 % Oral drops: 10 mg/100ml Tablet: 75mg; 81mg; 300mg; 500 mg Injection: 0.05mg/ml Transdermal patch: 12,25,50,75,100mcg/hr Injection: 100mg/ 2 ml Injection: 50mg Tablet: 50mg Injection: 10mg; 20mg Tablet: 30mg 2.3 Medicines used to treat gout 22 allopurinol Tablet: 100 mg; 300mg 2.4 Disease modifying agents used in rheumatoid disorders (DMARDs) 23 azathioprine Tablet: 50mg 24 hydroxychloroquine Solid oral dosage form: 200mg Tablet: 2.5mg 25 methotrexate Injection: 50mg 26 penicillamine Solid oral dosage form: 250mg 27 sulfasalazine Tablet: 500mg 1 Egptian Essential Drug List 2012-2013 3. ANTIALLERGICS AND MEDICINES USED IN ANAPHYLAXIS 28 Prednisolone Tablet: 5mg; 25mg Syrup: 5mg/5ml Injection: 25mg ,500mg,1g 29 Chlorpheniramine Tablet: 4 mg Injection: 5 mg/ml Syrup: 2mg/5ml 30 dexamethasone 31 epinephrine (adrenaline) 32 hydrocortisone Injection: 4 mg/ml Syrup: 2mg/5ml Tablet: 0.5mg; 0.75mg Injection: 1mg/ml Tablet: 10 mg Injection: 100mg; 250 mg;500 mg 4. ANTIDOTES AND OTHER SUBSTANCES USED IN POISONINGS 4.1 Non-specific 33 charcoal, activated 4.2 Specific 34 DL Methionine 35 acetylcysteine 36 37 38 39 40 41 42 43 45 46 atropine calcium gluconate naloxone penicillamine sodium nitrite sodium thiosulfate deferoxamine dimercaprol sodium calcium edetate succimer Powder: 25g Tablet: 250mg Injection: 200mg/ml Oral liquid: 10% ; 20% Injection: 1mg/ml Injection: 100mg/ml Injection: 400mcg/1ml Solid oral dosage form: 250mg Injection: 30mg/ml Injection: 250mg/ml Powder for injection: 500mg Injection in oil: 50mg/ml Injection: 200mg/ml Solid oral dosage form: 100mg 5. ANTICONVULSANTS/ANTIEPILEPTICS Syrup: 100mg/5ml Tablet : 100mg;200mg; 400mg supp 125mg; 250mg Tablet: 2mg Injection: 10mg Injection: 2mg/ml Tablet: 2mg Injection: 500mg/ml; 10% in 5ml Injection: 200 mg/ml; 40mg/ml Oral liquid: 15mg/5ml Tablet: 100mg 47 carbamazepine 48 diazepam 49 lorazepam 50 magnesium sulfate 51 phenobarbital 52 phenytoin Capsule: 50 mg; 100mg Injection: 250mg/5ml; 50mg/ml Syrup: 30mg/5ml 53 valproic acid (sodium valproate) Syrup: 250mg/5ml Tablet: 500mg ; 250mg Injection: 500mg/5ml Oral drops: 200mg/ml 54 ethosuximide Capsule: 250 mg. Oral liquid: 250 mg/5 ml 6. ANTI-INFECTIVE MEDICINES 6.1.1 Intestinal anthelminthics 55 albendazole Tablet: 200mg Syrup: 20mg/ml 2 Egptian Essential Drug List 2012-2013 56 levamisole 57 mebendazole 58 niclosamide 59 praziquantel Tablet: 40mg Suspension: 40mg/5ml Tablet: 100mg Suspension: 100mg/5ml Tablet: 500 mg Tablet: 600 mg Syrup: 600mg/5ml 6.1.2 Antifilarials 60 albendazole 61 diethylcarbamazine 62 ivermectin Tablet: 200mg Syrup: 20mg/ml Tablet: 50mg; 100mg Tablet : 3mg; 6mg lotion: 1% Suspension: 10mg/10ml 6.1.3 Antischistosomals and other antitrematode medicines 63 praziquantel Tablet: 600mg Syrup: 600mg/5ml 6.2 Antibacterials 6.2.1 Beta Lactam medicines 64 amoxicillin Suspenion: 125/5ml; 250/5ml Capsule: 250mg; 500mg; 1g Powder for injection: 250mg; 500mg ; 1g 65 amoxicillin + clavulanic acid Oral liquid: 156 mg/5 ml; 312mg/5 ml; 228/5ml;457/5ml Tablet: 375mg; 625mg; 1gm Injection: 600mg, 1.2g 66 ampicillin 67 68 69 benzathine benzylpenicillin benzylpenicillin cefazolin 70 cefixime 71 ceftriaxone 72 phenoxymethylpenicillin 73 cefotaxime 74 ceftazidime 6.2.2 Other antibacterials 75 clindamycin 76 Cefadroxil 77 Gentamicin 78 Neomycin 79 Clarithromycin 80 Doxycyclin 81 Chloramphenicol 82 Vancomycin 83 Co-Trimoxazole ( sulphamethoxazole + trimethoprim ) Injection: 250mg; 500mg; 1g Tablet: 500mg, 250mg Syrup: 250mg/5ml ,125mg/5ml Powder for injection: 1.2 million U Powder for injection: 0.6 million U;1.2million U Powder for injection: 250mg; 500mg; 1 g Capsule: 200mg; 400 mg Syrup : 100mg/5ml Powder for injection: 250 mg; 500mg; 1 g Suspension: 250 mg/5 ml Tablet: 250 mg Injection: 250 mg; 500 mg ; 1g Injection: 250mg; 500mg; 1 g Capsule: 150ng; 300mg Injection: 150mg/ml Capsule: 250mg ; 500mg; 1g Suspension: 125mg ; 250mg; 500mg/5ml Oral drops: 100mg/ml Injection: 20 mg;40 mg; 80 mg Tablet: 500mg; 350IU Suspenion: 125mg Capsule: 250mg ; 500mg Suspension: 125mg/ 5ml, 250mg/ 5ml Injection: 500mg vial Capsule: 100mg, 50 mg Injection: 1g Capsule: 250mg ; 500mg Suspension: 125mg/5ml , 250mg/5ml; 500mg/5ml Injection: 500mg; 1g Suspension: (40mg/200 mg)/5ml Tablet: 80mg/400mg; 800mg/160mg 3 Egptian Essential Drug List 2012-2013 84 Ciprofloxacin 85 Nitrofurantoin 6.2.3 Antileprosy medicines 86 Clofazimine 87 Dapsone 88 Rifampicin 6.2.4 Antituberculosis medicines 89 Pyrazinamide 90 Ethambutol 91 Rifampicin + Isoniazid + Pyrazinamide + Ethambutol 92 Rifampicin + Isoniazid + Pyrazinamide 93 Isoniazid +B6 94 Rifampicin + Isoniazid 95 Streptomycin 6.3 Antifungal medicines 96 fluconazole 97 griseofulvin 98 nystatin 99 amphotericin B 100 flucytosine 101 Itraconazole Tablet: 250mg; 500mg; 750mg Injection: 2mg/ml ( 50ml,100ml) Tablet: 50mg; 100mg Suspension: 25mg/5ml Capsule: 100mg Tablet :50mg; 100mg Capsule: 150mg ; 300mg Suspension: 100mg/5ml; 200 mg/5 ml Injection: 600mg Tablet: 500mg Tablet: 500mg Tablet: 150mg + 75mg + 400mg + 275mg Tablet: 120mg + 50mg + 30mg Tablet: 100mg Tablet: 300mg +150mg Injection: 1g Capsule: 50mg; 150mg; 200mg Injection: 2mg/ml Tablet: 125mg; 500mg Suspension: 125mg/5ml Syrup: 100 000 U/ml Tablet: 500 000 U Injection: 50mg/15ml Capsule: 250mg Infusion: 2.5g in 250ml Capsule: 100mg Oral liquid: 10mg/ml 6.4.1 Antiherpes medicines 102 aciclovir Suspension: 200mg/5ml ; 400mg/5ml Tablet: 200mg ; 400mg ;800mg Injection : 250mg; 500mg; 1 gm 6.4.2 Antiretrovirals 6.4.2.1 Nucleoside/Nucleotide reverse transcriptase inhibitors 103 abacavir (ABC) Oral liquid: 100mg/5ml Tablet: 300mg 104 didanosine (ddI) Buffered powder for oral liquid: 100mg; 167mg; 250mg Capsule: 125mg; 200mg; 250mg; 400mg Tablet: 25mg; 50mg; 100mg;150mg; 200mg 105 lamivudine (3TC) 106 stavudine (d4T) 107 tenofovir disoproxil fumarate (TDF) 108 zidovudine (ZDV or AZT) Oral liquid: 50mg/5ml Tablet: 150mg Capsule: 20mg; 30mg; 40mg Powder for oral liquid: 5mg/5ml Tablet: 300mg Capsule: 100mg; 250mg Oral liquid: 50mg/5ml Infusion: 10mg/ml Tablet: 300mg 6.4.2.2 Non-nucleoside reverse transcriptase inhibitors 109 nevirapine (NVP) 6.4.2.3 Protease inhibitors 110 atazanavir a 111 emtricitabine + tenofovir 112 lamivudine + zidovudine Oral liquid: 50mg/5ml Tablet: 200mg Solid oral dosage form: 150mg; 200mg Tablet: 200mg + 300mg Tablet: 150mg + 300mg 4 Egptian Essential Drug List 2012-2013 6.4.3 Antiviral For HCV 113 Pegylated alpha interferon + ribavirin 200 mg 6.4.4 Other antivirals 114 ribavirin 6.5 Antiprotozoal medicines 6.5.1 Antiamoebic and antigiardiasis medicines 115 diloxanide 116 metronidazole 6.5.2 Antileishmaniasis medicines 117 amphotericin B 6.5.3.1 For curative treatment 118 amodiaquine 119 artemether 120 artemether + lumefantrine 121 artesunate 122 artesunate + amodiaquine 123 chloroquine 124 doxycycline 125 mefloquine 126 sulfadoxine + pyrimethamine Solid oral dosage form: 200mg; 400mg; 600mg Tablet: 500 mg (furoate) Injection: 5mg/ml Suspension: 125mg /5 ml Tablet: 250mg; 500mg Powder for injection: 50 mg in vial. Tablet: 200mg Oily injection: 20mg/ml; 80 mg/ml Suspension: 300mg/ml Tablet: 20mg + 120mg Tablet: 50 mg; 60m Tablet: (25mg + 67.5mg); (50mg + 135mg); (100mg + 270mg) Suspension:80 mg/5 ml Tablet: 250mg Injection: 200mg/5ml Capsule: 100 mg Tablet: 250 mg (as hydrochloride). * To be used in combination with artesunate 50 mg. Tablet: 500 mg + 25 mg. * Only in combination with artesunate 50 mg. 6.5.3.2 For prophylaxis 127 chloroquine 128 doxycycline 129 mefloquine 6.5.4 Antipneumocystosis and antitoxoplasmosis medicines 130 pyrimethamine 131 sulfadiazine 132 sulfamethoxazole + trimethoprim 133 pentamidine Suspension:80 mg/5ml Tablet: 250mg Injection: 200mg/5ml Capsule: 100mg Tablet: 250mg Tablet: 25mg Tablet: 500mg Suspension: (40mg/200 mg)/5ml Tablet: 80mg + 400mg; 800mg + 160mg Tablet: 200 mg; 300 mg 7. ANTIMIGRAINE MEDICINES 7.1 For treatment of acute attack 134 acetylsalicylic acid 135 ibuprofen 136 paracetamol 137 Ergotamine 7.2 For prophylaxis 138 propranolol Tablet: 75mg; 81mg; 300 mg; 500 mg Tablet: 200mg; 400mg Suspension:100mg/5ml Suppository: 100mg; 30mg; 500mg Oral liquid: 120mg/5 ml Tablet: 500mg Injection: 1% Oral drops: 10 mg/100ml Capsule: 1.5mg Tablet: 10mg; 40mg amp.:1mg/1ml 5 Egptian Essential Drug List 2012-2013 8. ANTINEOPLASTIC, IMMUNOSUPPRESSIVES AND MEDICINES USED IN PALLIATIVE CARE 8.1 Immunosuppressive medicines 139 Penicillamine 140 azathioprine 141 ciclosporin 142 allopurinol 143 asparaginase 144 bleomycin 145 calcium folinate 146 carboplatin 147 chlorambucil 148 cyclophosphamide 149 150 151 152 153 154 cytarabine dacarbazine dactinomycin daunorubicin docetaxel doxorubicin 155 etoposide 156 157 158 159 fluorouracil hydroxycarbamide ifosfamide mercaptopurine 160 mesna 161 methotrexate 162 paclitaxel 163 procarbazine 164 thioguanine 165 vinblastine 166 vincristine 8.3 Hormones and antihormones 167 dexamethasone 168 methylprednisolone 169 prednisolone 170 tamoxifen Capsule: 250mg Tablet : 50mg Capsule: 25mg ; 50mg;100mg Syrup: 100mg/ml;50 mg/ml Injection: 50mg/1ml Tablet: 100 mg; 300mg injection: 10000 IU Powder for injection: 15.000U Injection: 3 mg/ml; 10mg/ml; 50mg/5ml Tablet: 15mg Injection: 10mg/ml Tablet: 2mg Tablet: 50mg Injection: 500mg ;1g Powder for injection: 20 mg/ml; 100mg/1ml Powder for injection: 100 mg;200mg Powder for injection: 500mcg Powder for injection : 50mg; 20mg/4ml Injection: 20mg/0.5ml; 20mg/ml; 40 mg/ml Injection: 2mg/ml Injection: 20 mg/ml Capsule : 50 mg Injection: 25mg/ml; 50mg/ml; 100mg/ml Solid oral dosage form: 500 mg injection: 1 g; 2g Tablet: 50mg Injection: 100mg/ml Tablet: 400mg; 500mg; 600 mg. Injection: 2.5mg/ml;100mg/ml Tablet: 2.5mg Injection: 6mg/ml Capsule: 50mg Solid oral dosage form: 40 mg Injection: 1mg/ml Powder for injection: 1 mg/ ml Tab: 0.5 mg;0.75mg Injection: 40mg/ml ;1g ;500mg Tablet: 4mg; 8mg Oral liquid: 5mg/ml Tablet: 5mg; 25mg Injection: 25mg/ml Tablet: 10 mg ;20 mg 9. ANTIPARKINSONISM MEDICINES 171 Benzatropine Mesylate 172 Carbidopa + Levodopa 173 biperiden Tablet: 2mg Injection: 1mg/ml Tablet: 10/100 ; 12.5/50 ; 25/100 ; 25/205 Injection: 5mg/1ml Tablet: 2mg 10. MEDICINES AFFECTING THE BLOOD 10.1 Antianaemia medicines 174 ferrous salt Syp: 125mg/5ml Tablet: 200 mg 6 Egptian Essential Drug List 2012-2013 175 ferrous salt + folic acid 176 folic acid 177 hydroxocobalamin 10.2 Medicines affecting coagulation 178 heparin Sodium 179 low molecular weight heparin 180 phytomenadione 181 protamine sulfate 182 tranexamic acid 183 warfarin Tablet equivalent to 60 mg iron + 400 mcg folic acid Tablet contains 250mcg folic acid + 183 mg ferrous fumarate 300mcg folic acid + 200 mg ferrous fumarate 350 mcg folic acid + 256.3mg iron sulphate Tablet: 0.5mg; 5mg Injection: 500mcg, 1mg/ml Injection: 5000 IU Prefilled syringe Injection: 1mg/ml; 10 mg/ml Tablet: 10mg ;5mg Injection: 10mg/ml Injection: 100mg/ml in 10ml ampoule; 100 mg/ml in 5ml Tablet: 500mg Tablet: 1 mg ; 2mg; 3 mg ; 5 mg 11. BLOOD PRODUCTS AND PLASMA SUBSTITUTES 11.1 Plasma substitutes 184 dextran 70 11.2 Plasma fractions for specific use 185 factor VIII concentrate 186 factor IX complex (coagulation factors, II, VII, IX, X) concentrate 187 human normal immunoglobulin Injectable solution: 70 Injection Injection Injection 12. CARDIOVASCULAR MEDICINES 12.1 Antianginal medicines 188 Isosorbide dinitrate 189 Isosorbide mononitrate 190 bisoprolol 191 glyceryl trinitrate 192 verapamil 12.2 Antiarrhythmic medicines 193 bisoprolol 194 digoxin 195 epinephrine (adrenaline) 196 lidocaine 197 verapamil 198 amiodarone 12.3 Antihypertensive medicines 199 Lisinopril 200 Lisinopril + hydrochlorothiazide 201 Valsartan 202 amlodipine 203 bisoprolol 204 enalapril 205 hydralazine 206 hydrochlorothiazide 207 methyldopa Sublingual tablet: 5mg; 10mg Tablet: 20mg, 30mg, 40mg, 80mg,100mg Tablet: 2.5mg ; 5 mg;10 mg. Sublingual table: 2.5 mg; 500 mcg Injection: 5 mg/ml;1 mg/ml,50 mg/ml S.R. capsule: 2.5mg Tablet: 80mg,40mg ,240mg Injection: 5mg/2ml Tablet: 2.5 mg ; 5 mg;10 mg. Oral liquid: 50mcg/ml. Tablet: 250mcg Injection 0.025% Injection: 1mg/ml Injection: 20% Tablet: 80mg; 40mg; 240mg Injection 5mg/2 ml Injection: 150mg Tablet: 200mg Tablet: 5mg ; 10mg ; 20mg Tablet: 20 + 12.5mg Tablet: 40mg; 80mg;160mg; 320mg Tablet: 5mg ;10mg Tablet: 2.5 mg ; 5 mg;10 mg Tablet: 5 mg ;10mg;20mg. Powder for injection: 20 mg Solid oral dosage form: 12.5mg; 25mg Tablet: 250 mg;500 mg 7 Egptian Essential Drug List 2012-2013 12.4 Medicines used in heart failure 208 Dobutamine 209 bisoprolol 210 digoxin 211 Lisinopril 212 furosemide 213 hydrochlorothiazide 214 dopamine 12.5 Antithrombotic medicines 215 acetylsalicylic acid 216 clopidogrel 12.6 Lipid-lowering agents 217 Atorvastatin 218 fenofibrate(micronized) 12.7 fibrinolytic 219 streptokinase Injection: 250mg/20ml Tablet: 2.5 mg ; 5 mg;10 mg Oral liquid: 50mcg/ml Tablet: 250mcg Injection: 0.025% Tablet: 5mg ; 10mg ; 20mg Injection: 10 mg/ml Tablet:20mg; 40 mg ;500 mg Solid oral dosage form: 12.5mg; 25 mg Injection: 40 mg/ml Tablet: 75mg; 81mg; 300 mg; 500 mg Tablet: 75mg Tablet: 10mg; 20mg; 80mg Tablet: 160mg; 200mg Vial: 750,000 I.U. ; 1500,000 I.U 13. DERMATOLOGICAL MEDICINES (topical) 13.1 Antifungal medicines 220 econazole 221 miconazole 222 terbinafine 13.2 Anti-infective medicines 223 fusidic acid 224 erythromycin+ zinc acetate 225 Chloramphenicol 226 silver sulfadiazine 13.3 Anti-inflammatory and antipruritic medicines 227 betamethasone 228 calamine 229 hydrocortisone 13.4 Medicines affecting skin differentiation and proliferation 230 benzoyl peroxide 231 coal tar 232 salicylic acid 233 urea 13.5 Scabicides and pediculicides 234 benzyl benzoate 235 permethrin powder Topical cream: 1% Cream or ointment: 2% Powder: 0.4gm/20g Lotion: 2% Gel Cream: 1% or Ointment: 1% Ointment or cream: 2% Lotion Ointment: 1% Cream: Cream: 1% Ointment: 0.05% Cream: 0.1% Lotion Cream or ointment: 1% Gel: 5%, 10% Solution: 5% Lotion: 6% Cream : 10% Lotion: 25% Gel: 10% Cream: 10% Cream or Lotion or Ointment: 2.5% , 5% Shampoo: 1% 14. DIAGNOSTIC AGENTS 14.1 Ophthalmic medicines 236 tropicamide 14.2 Radiocontrast media 237 Diatrizoate Meglumine 238 Iodised Oil 239 Iopamidol Eye drops: 0.5% ; 1% Injection Injection Injection: 200 mg ; 612 mg/ml; 755 mg/ml 8 Egptian Essential Drug List 2012-2013 240 amidotrizoate 241 barium sulfate 242 iohexol Injection: 140 mg to 420 mg iodine (as sodium or meglumine salt)/ml in 20ml ampoule;76% (Aqueous solution) amp.; 65 % oral powder Injection: 140 mg to 350 mg iodine/ml in 5?ml; 10?ml; 20?ml ampoules. 15. DISINFECTANTS AND ANTISEPTICS 15.1 Antiseptics 243 Povidone Iodine 244 chlorhexidine 245 ethanol 15.2 Disinfectants 246 chlorine base compound 247 chloroxylenol 248 glutaral Solution: 7.5%,10% Mouth Wash: 125mg/100ml, 0.1gm/100ml Topical solution: 1% Solution: 70% Powder: (0.1% available chlorine) for solution. Solution: 4.8%. Solution: 2% 16. DIURETICS 249 Amiloride + hydrochlorothiazide 250 furosemide 251 252 253 254 hydrochlorothiazide mannitol spironolactone Chlorthalidone Tablet: 5mg +50 mg Injection: 10 mg/ml ampoule. Tablet: 20mg; 40 mg ;500 mg. Solid oral dosage form: 12.5mg; 25 mg Injectable solution: 10%; 20% Tablet: 25mg; 50mg ; 100mg Tablet: 25mg; 50mg 17. GASTROINTESTINAL MEDICINES 255 pancreatic enzymes 17.1 Antiulcer medicines 256 omeprazole 257 ranitidine 258 Aluminium Hydroxide Gel & Magnesium salts or comb. Soild Oral dosage form Injection: 40 mg Capsule: 20mg;40mg Tablet: 150mg ; 300mg Injection: 50mg/5ml ; 25mg/ml Tablet Suspension 17.2 Antiemetic medicines 259 dexamethasone Tablet: 0.5 mg; 0.75mg Suspension: 2mg/5ml Injection: 4mg/ml 260 metoclopramide Injection: 10mg Tablet: 10mg Suppository: 20mg 261 Domperidone 262 ondansetron Tablet: 10mg Suspension: 1mg/1ml Suppository: 10mg; 30mg; 60mg Injection: 4mg/2ml Tablet: 4mg; 8mg 17.3 Anti-inflammatory medicines 263 sulphasalazine 264 hydrocortisone Retention enema Suppository: 500mg Tablet: 500mg Retention enema Suppository: 25g Tablet: 10mg Injection: 100mg; 250mg;500mg 17.4 Laxatives 265 glycerin 266 Bisacodyl Suppository: infant Suppository: Adult Tablet: 5mg; 10mg Suppository: 5mg inf ; 10 mg adult 9 Egptian Essential Drug List 2012-2013 267 Lactulose 268 senna 17.5 Medicines used in diarrhoea 269 Nifuroxazide Syrup: 67gm/100ml Tablet: 7.5mg; 20mg Capsule: 200mg Suspension: 200mg/5ml 17.5.1 Oral rehydration 270 oral rehydration salts glucose: 75 mEq sodium: 75 mEq or mmol/L chloride: 65 mEq or mmol/L potassium: 20 mEq or mmol/L citrate: 10 mmol/L osmolarity: 245 mOsm/L glucose: 13.5 g/L sodium chloride: 2.6 g/L potassium chloride: 1.5 g/L trisodium citrate dihydrate+: 2.9 g/L + trisod 17.5.2 Medicines for diarrhoea in children 271 zinc sulfate Solid oral dosage form: 20mg Powder for oral suspension:10mg/5ml , 20mg/5ml 17.7 Liver diseases 272 silymarin containing comp. Solid oral dosage form: 140mg Powder for oral suspension: 1gm/100ml 17.8 Antispasmodic 273 Mebeverine Solid oral dosage form: 100mg; 200mg Suspension: 10mg/ml 18. HORMONES, OTHER ENDOCRINE MEDICINES AND CONTRACEPTIVES 18.1 Adrenal hormones and synthetic substitutes 274 Desmopressin Acetate 275 fludrocortisone 276 hydrocortisone Tablet: 0.1mg; 0.2mg Sublingual table: 60mcg; 120mcg Nasal spray: 10mcg/dose Injection: 15mcg/ml; 4mcg/ml Tablet: 0.1mg Tablet: 10mg Injection: 100mg; 250mg;500mg 18.2 Androgens 277 testosterone 18.3 Contraceptives 18.3.1 Oral hormonal contraceptives 278 ethinylestradiol + † levonorgestrel 279 ethinylestradiol + † norethisterone 18.3.2 Injectable hormonal contraceptives 280 medroxyprogesterone acetate 18.3.3 Intrauterine devices 281 copper containing device 18.4 Emergency contraceptive 282 levonorgestrel 18.5 Insulins and other medicines used for diabetes 283 glibenclamide 284 glucagon 285 insulin injection (soluble) 286 intermediate?acting insulin 287 Insulin mix 288 metformin 18.6 Ovulation inducers 289 clomifene 18.8 Thyroid hormones and antithyroid medicines Injection: 250mg/ml Capsule: 40mg Tablet: 35mcg + 150mcg Tablet: 30mcg + 1mg ; 30mcg + 1.5 mg Injection : 150mg / 1ml Tablet: 1.5mg Tablet: 2.5 mg; 5 mg. Injection: 1mg Injection: 100 IU/ml Injection: 100 IU/ml Injection: 70/30 IU/ml ; 50/50 IU/ml Tablet : 500 mg.,850 mg,1000mg Tablet: 50 mg 10 Egptian Essential Drug List 2012-2013 290 levothyroxine 291 Carbimazole 292 Propyl thiouracil Tablet: 25mcg; 50mcg ; 100mcg Tablet: 5mg Tablet: 50mg 19. IMMUNOLOGICALS 19.1 Diagnostic agents 293 tuberculin, purified protein derivative (PPD) 19.2 Sera and immunoglobulins 294 Anti-Scorpion Serum 295 Gas-Gangrene Antitoxin (Polyvalent) 296 Hyperimmunoglobulins Hepatitis HB 297 anti?D immunoglobulin (human) 298 antitetanus immunoglobulin (human) 299 antivenom immunoglobulin 300 diphtheria antitoxin 301 rabies immunoglobulin 19.3 Vaccines 302 Diphtheria + Tetanus Toxoids + Pertussis Vaccine 303 Mumps + Measles + Rubella Virus Vaccine 304 Typhoid - Paratyphoid A&B+ Tetanus 305 Poliomyelitis Vaccine ( inactivated ) 306 BCG vaccine 307 Haemophilus influenzae type b vaccine 308 hepatitis B vaccine 309 meningococcal meningitis vaccine 310 pneumococcal vaccine 311 poliomyelitis vaccine 312 rabies vaccine 313 tetanus vaccine 314 typhoid vaccine 315 yellow fever vaccine Injection Injection Injection Injection Injection Injection Injection Injection Injection Injection Injection Injection Injection Injection Injection Injection Injection Injection Injection Injection Injection Injection Injection 20. MUSCLE RELAXANTS (PERIPHERALLY-ACTING) AND CHOLINESTERASE INHIBITORS 20.1 central Muscle Relaxant 316 Orphenadrine 20.2 Neuromuscular Blockers 317 atracurium 318 suxamethonium 319 vecuronium 20.3 Choline Esterase Inhibitors 320 neostigmine 321 pyridostigmine Injection: 30mg Tablet: 100mg Injection: 10mg/ml Injection: 50 mg/ml Injection: 4mg; 10mg Injection: 2.5 mg/ml Tablet: 15mg Tablet: 60mg Tablet S.R: 180mg Syrup: 60mg/5ml 21. OPHTHALMOLOGICAL PREPARATIONS 21.1 Anti-infective agents 322 Chloramphenicol 323 Oxytetracycline+ Polymyxin 324 Sulfacetamide sodium 325 gentamicin 326 tetracycline 327 aciclovir 21.2 Anti-inflammatory agents Eye drops: 0.5% Eye Ointment: 1% Eye Ointment Eye drops: 15 % ; 20 % ; 30 % Eye drops: 0.3% Eye Ointment: 0.3% Eye ointment: 1% Eye Ointment: 3% 11 Egptian Essential Drug List 2012-2013 328 prednisolone 21.3 Local anaesthetics 329 Benoxinate 21.4 Miotics and antiglaucoma medicines 330 acetazolamide 331 pilocarpine 332 timolol Eye drops: 0.5%; 1% Eye gel: 0.5% Eye drops: 0.4% Solid oral dosage form: 250 mg; 500mg Injection: 500mg Eye drops: 1%; 2%; 3%; 4% Eye drops: 0.25%; 0.5% Eye gel: 0.1% 21.5 Mydriatics 333 atropine 334 cyclopentolate Eye ointment : 0.01 Eye drops : 0.01 Eye drops: 0.5%; 1% 22. OXYTOCICS AND ANTIOXYTOCICS 22.1 Oxytocics 335 Methyl† ergometrine 336 oxytocin 22.2 Antioxytocics (tocolytics) 337 Ritodrin 338 nifedipine Injection: 200mcg/1ml Tabet: 0.125mg Injection: 5IU; 10IU Tablet: 10mg Injection: 10mg/ml Immediate?release capsule: 10mg S.R. tablet: 20mg 23. PERITONEAL DIALYSIS SOLUTION Parenteral solution: calcium 339 intraperitoneal dialysis solution (of appropriate composition) chloride+dextrose+sod.chloride+mag.chloride+sod. Chloride+sod.acetate+sod.metabis ulfite 24. MEDICINES FOR MENTAL AND BEHAVIOURAL DISORDERS 24.1 Medicines used in psychotic disorders 340 chlorpromazine 341 trifluperazine 342 haloperidol 343 haloperidol decanoate 24.2 Medicines used in mood disorders 24.2.1 Medicines used in depressive disorders 344 Imipramine 345 amitriptyline 346 fluoxetine Injection: 25mg/ml Oral liquid: 25mg/5 ml Tablet: 25mg; 100mg Tablet : 1 mg; 5mg Injection: 5mg/ml Oral liquid: 2mg/ml Solid oral dosage form: 0.5mg; 1.5mg; 5mg; 10mg Injection: 50mg/ml; 100mg/ml Tablet: 10mg; 25mg Tablet: 10mg; 25mg; 50mg S.R capsule: 75mg Solid oral dosage form: 20mg Delayed release capsule: 90mg 24.2.2 Medicines used in bipolar disorders 347 carbamazepine 348 lithium carbonate 349 valproic acid /sodium valproate Tablet: 100 mg; 200 mg S.R. tablet:.200mg;400mg Syrup: 2% Rectal Suppository: 125mg; 250mg C.R. tablet: 400mg Tablet: 100mg; 200mg; 500mg Syrup : 200mg/5ml M.r. capsule: 100mg; 200mg; 300mg; 500mg Injection: 500mg/5ml 24.3 Medicines for anxiety disorders 12 Egptian Essential Drug List 2012-2013 350 diazepam 351 bromazepam 24.4 Medicines used for obsessive compulsive disorders 352 clomipramine Tablet: 2mg; 5mg; 10mg Syrup: 2mg/5ml Suppository: 5mg; 10mg Injection: 5mg/ml I.v/I.m Tablet: 1.5mg, 3mg, 6mg Capsule: 10mg; 25mg S.R. capsule: 75mg 24.5 Medicines for disorders due to psychoactive substance use 353 methadone The medicines should only be used within an established support programme. 25. MEDICINES ACTING ON THE RESPIRATORY TRACT 25.1 Antiasthmatic and medicines for chronic obstructive pulmonary disease 354 beclomethasone Inhalation (aerosol): 50mcg/ dose; 100mcg/dose; 250mcg/dose Nebulizer vial: 0.25mg/ml; 0.5mg/ml 355 budesonide Turbuhaler: 100mcg/dose; 200mcg/dose Inhalation powder in capsule + inhaler device: 400mcg 356 adrenaline Injection: 1mg/ml 357 ipratropium bromide Inhalation (aerosol): 20mcg/dose 358 Nebulizer vial: 0.5mg/2ml , 250mcg/2ml Inhalation (aerosol): 100mcg/dose; 200mcg/dose Tablet: 2mg; 4mg; 8mg 359 salbutamol Syrup: 2mg/5ml Injection: 0.5mg/ml; 1mg/ml 360 Sodium cromoglycate Spinhalar capsule: 20mg 25.2 Antihistamines Tablet: 60mg; 120mg; 180mg 361 Fexofenadine Syrup: 30mg/5ml Tablet: 1mg 362 Ketotifen Syrup: 1mg/5ml Tablet: 4mg 363 Chlorpheniramine Maleate Syrup: 2mg/5ml Tablet: 10mg 364 Loratadine Syrup: 1mg/ml 25.3 Nasal decongestants Tablet: 60mg 365 Pseudoephedrine S.R. tablet: 120 mg Syrup: 10mg/5ml 366 Pseudo ephedrine + Loratidine Tablet: 120mg + 5mg 25.4 Bronchodilators Injection: 25mg/ml 367 Aminophylline or other theophylline salts Syrup: 0.116g/5ml Suppository: 250mg infantile; 360mg adult S.R. tablet: 100mg; 200 mg; 300mg; 400 mg 368 Anhydrous theophylline Syrup: 60mg/5ml 369 Terbutaline Tablet: 2.5mg; 5mg Inhalation: 0.5mg/dose Syrup: 1.5mg/5ml Nebulizing solution: 2.5mg/ml 25.5 Cough Suppressant 370 Clobutinol 371 Dextromethorphan 40mg Tablet: 40mg Syrup: 20mg/5ml Tablet: 10mg Syrup: 7.5mg/5ml; 10mg/5ml Oral drops: 10mg/ml 25.6 Mucolytics 372 Carbocysteine Capsule:375mg Syrup: 125mg/5ml; 250mg/5ml 13 Egptian Essential Drug List 2012-2013 373 Ambroxol Tabet: 30mg S.R. Capsule: 75mg Syrup: 7.5/ml Oral Drop: 15mg/ml injection: 15mg/2ml 374 Bromhexine Tablet: 8mg Elixir: 4mg/5ml Oral drops: 30mg/15ml 25.7 Expectorants 375 Guaiphenesin containing preparation 25.8 immunosupressive Corticosteroid agents 376 Hydrocortisone 377 Prednisolone 378 Dexamethasone 379 Triamcinolone Tablet: 10mg Injection: 100mg; 250mg;500mg Tablet: 5mg; 25mg Syrup: 5mg/5ml Injection: 25mg Injection: 4mg/ml Syrup: 2mg/5ml Tablet: 0.5mg; 0.75mg Injection: 40mg/ml Tablet: 4mg 26. SOLUTIONS CORRECTING WATER, ELECTROLYTE AND ACID-BASE DISTURBANCES 26.1 Oral 380 oral rehydration salts glucose: 75 mEq sodium: 75 mEq or mmol/L chloride: 65 mEq or mmol/L potassium: 20 mEq or mmol/L citrate: 10 mmol/L osmolarity: 245 mOsm/L glucose: 13.5 g/L sodium chloride: 2.6 g/L potassium chloride: 1.5 g/L trisodium citrate dihydrate+: 2.9 g/L + trisod 381 potassium chloride Tablet: 600mg Syrup: 6% ; 3.3g/100ml 26.2 Parenteral 382 Ringer Lactate Solution 383 Human Albumin 384 Isoprenaline 385 glucose 386 glucose with sodium chloride 387 potassium chloride 388 sodium chloride 389 sodium bicarbonate 390 sodium lactate 26.3 Miscellaneous 391 water for injection Injectable solution Injectable solution: 20% Injectable solution: 200mg/ml Injectable solution: 5% (isotonic); 10% (hypertonic); 50% (hypertonic) Injectable solution: 4% glucose, 0.18% sodium chloride Injectable solution: 5% glucose, 0.9% sodium chloride Injection: 0.15% ; 4% ; 7.5% ; 15% Injection: 0.45% ; 0.9% Injection: 4.2% ; 8.4% Injection: 1/6 molar 2ml; 5ml; 10ml ampoules 27. VITAMINS AND MINERALS 392 Vit.B12 393 Vitamin B containing at least(B1, B6,B12) 394 Vit. K1 (Phytomenandione) Injection: 1mg Tablet: 1mg Tablet Syrup Injection Tablet: 5mg; 10mg Injection: 10mg/ml 14 Egptian Essential Drug List 2012-2013 395 Vit. D + Calcium 396 Calcium carbonate 397 Alfacalcidole 398 cholecalciferol (Vit. D3) 399 iodine 400 Vitamin B6 (Pyridoxine) 401 Vitamin A 402 Vitamin B2 (Riboflavin) 403 calcium gluconate Tablet: Tablet: 500mg; 1200mg Tablet: 0.25mcg; 0.5mcg; 1mcg Injection: 2mcg/ml Oral drops: 2mcg/ml Oral drops: 2800 I.U./ml Injection: 200000 I.U. Oral solution: 5% Oral solutio KI: 10% Tablet: 50mcg Injection: in combination Capsule: 25 000 I.U. Tablet: 5 mg Injection: 10% 28. EAR, NOSE AND THROAT CONDITIONS IN CHILDREN 404 chloramphenicol 405 ciprofloxacin 406 xylometazoline 407 budesonide 408 Sodium cromoglycate Ear drops: 5% Topical drops: 0.3% Nasal spray: 0.1% Nasal drops: 0.05% , 0.1% Nasal spray: 32mcg/dose; 64mcg Nasal drops: 2% ; 4% 29. SPECIFIC MEDICINES FOR NEONATAL CARE 409 caffeine citrate 410 ibuprofen 411 prostaglandin E Injection: 20 mg/ml (equivalent to 10 mg caffeine base/ml) Oral liquid: 20 mg/ml (equivalent to 10 mg caffeine base/ml) Solution for injection: 5 mg/ml oral drops: 5% ; 4% Prostaglandin E1: 0.5 mg/ml in alcohol. (ALPROSTADIL) Prostaglandin E2: 1 mg/ml Prostaglandin E1(ALPROSTADIL) Injection: 20mcg Prostaglandin E2 (DINOPROSTONE) Inj: 10 mg/ml ; 1 mg/0.75 ml ; 5mg/ml 30. Anti-Haemmoroidal 412 Prednisolone+Lidocaine containing preparation 413 Hydrocortisone+Lidocaine containing preparation Table 1: Medicines with age or weight restrictions 1 surfactant 2 atazanavir 3 atropine 4 benzyl benzoate 5 betamethasone topical preparations 6 cefazolin 7 ceftriaxone 8 chlorphenamine 9 diloxanide 10 doxycycline 11 efavirenz 12 emtricitabine 13 fluoxetine 14 ibuprofen 15 mefloquine 16 metoclopramide 17 ondansetron 18 saquinavir 19 silver sulfadiazine 20 tetracaine 21 trimethoprim Ointment and Suppository Ointment and Suppository Suspension for intratracheal instillation: 25 mg/ml or 80 mg/ml. >25 kg >3 months >2 years Hydrocortisone preferred in neonates >1 month >41 weeks corrected gestational age >1 year >25 kg >8 years (except for serious infections e.g. cholera) >3 years or >10 kg >3 months >8 years >3 months (except IV form for patent ductus arteriosus) >5 kg or >3 months Not in neonates >1 month >25 kg >2 months Not in preterm neonates >6 months 15 Egptian Essential Drug List 2012-2013 22 xylometazoline Term >3 months Definition Solid oral dosage form Refers to tablets or capsules or other solid dosage forms such as melts that are immediate?release preparations. It implies that there is no difference in clinical efficacy or safety between the available dosage forms Tablets Refers to: • uncoated or coated (film?coated or sugar?coated) tablets that are intended to be swallowed whole; • unscored and scored; • tablets that are intended to be chewed before being swallowed; • tablets that are intended to be dispersed 3 Tablets (qualified) Refers to a specific type of tablet: chewable tablets that are intended to be chewed before being swallowed; dispersible tablets that are intended to be dispersed in water or another suitable liquid before being swallowed; 4 Capsules Refers to hard or soft capsules. The term capsule without qualification is never intended to allow any type of modified release capsule. 5 Capsules (qualified) The term capsule with qualification refers to gastro?resistant (such capsules may sometimes be described as enteric?coated or as delayed? release), prolonged?release or another modified?release form. 6 Granules Preparations that are issued to patient as granules to be swallowed without further preparation, to be chewed, or to be taken in or with water or another suitable liquid. The term granules without further qualification is never intended to allow any type 7 Oral powder Preparations that are issued to patient as powder (usually as single? dose) to be taken in or with water or another suitable liquid. 1 2 Liquid preparations intended to be swallowed i.e. oral solutions, suspensions, emulsions and oral drops, including those constituted from powders or granules, but not those preparations intended for oromucosal administration e.g. gargles and mouthwashes. 8 Oral liquid 9 Injection Refers to solutions, suspensions and emulsions including those constituted from powders or concentrated solutions. 10 Injection (qualified) Route of administration is indicated in parentheses where relevant. 11 Injection (oily) The term injection is qualified by (oily) in relevant entries. 12 Intravenous infusion Refers to solutions and emulsions including those constituted from powders or concentrated solutions. 13 14 Mode of administration To the eye 15 Topical 16 17 18 Rectal Vaginal Inhalation Term to be used Eye drops, eye ointments. For liquids: lotions, paints. For semisolids: cream, ointment. Suppositories, gel or solution. Pessaries or vaginal tablets. Powder for inhalation, pressurized inhalation, nebulizer. 16