Molecular and epidemiological studies of transmission routes and risk factors for infection by HTLV-1 are extremely important in order to implement control measures, especially because of the high prevalence of HTLV-1 in several regions of the world. San Salvador de Jujuy, Northwest Argentina, is a highly endemic area for HTLV-1 and foci of tropical spastic paraparesis/HTLV-1-associated myelopathy. To gain further insight into the role of intrafamilial transmission of HTLV-1 in a highly endemic region in Argentina. Cross-sectional study in Northwest Argentina. Epidemiological data and blood samples were collected from 28 HTLV-1 infected subjects (index cases) and 92 close relatives/cohabitants. HTLV-1 infection was diagnosed by detection of antibodies and proviral DNA. The LTR region was sequenced and analyzed for genetic distances (VESPA software), in addition to determination and identification of polymorphisms to define HTLV-1 family signatures. Fifty seven of the 120 subjects en...

Human T-lymphotropic virus type I (HTLV-I) infection was investigated in 168 Japanese immigrants (64 males and 104 females) living in the Tome-Acu county located in the State of Para, Brazil. The serological screening was performed using an enzyme-linked immunosorbent assay, and showed the presence of anti-HTLV in four women whose ages ranged from 50 to 88. Confirmation of infection and discrimination HTLV typing was performed using a nested PCR on the extracted DNA targeting the pX region. In three of the samples, infection was confirmed to be HTLV-I. Sequencing HTLV-I 5'LTR and the RFLP pattern using DraI and SacI endonucleases indicated that the virus is a member of the Cosmopolitan group. These three women originated from the Kyushu region, though two of the corresponding HTLV-I strains were phylogenetically related to the Japanese subgroup and the third to the Transcontinental subgroup, which probably reflects the geographical origin of the infected individuals. The Japanes...

Además de los servicios de consultoría estratégica y operativa, las empresas de consultoría también ofrecen programas de capacitación corporativa y desarrollo de habilidades para fortalecer a los equipos de trabajo. Estos servicios pueden ser cruciales para impulsar el crecimiento y la competitividad de tu negocio en Perú. Algunos de los servicios de capacitación y desarrollo de habilidades que puedes encontrar incluyen talleres y programas de formación en áreas clave, como liderazgo, gestión de proyectos, ventas y marketing. Además, los consultores pueden brindar asesoría en la implementación de una cultura de aprendizaje continuo, lo que permitirá a tus colaboradores actualizarse constantemente y adquirir nuevas competencias.

An interesting assemblage of ancient ceramic materials connected or potentially connected with gaming activities has been characterized from the archaeometric point of view. The materials (washer-like pieces, small spheres, and cubic dice, with and without inscriptions) were found in the Villa del Foro excavation (Alessandria, Italy). They are related to the early Ligurian population of the site and their frequent contacts with Etruscan both in Etruria and in the Po Valley, in a period spanning the early VI century BC till the first half of the V century BC. Starting from the materials evidence, hypotheses are proposed concerning their possible use and cultural meaning. The studied cubic dice are discussed in the wider context of the pre-Roman diffusion of these objects.