Avp
0 Followers
Recent papers in Avp
ABSTRACT Given the shortcomings of traditional heritage preservation practices in understanding the values that justify heritage protection, it is necessary to critically re-evaluate these practices adopted to physically protect the... more
ABSTRACT
Given the shortcomings of traditional heritage preservation practices in understanding the values that justify heritage protection, it is necessary to critically re-evaluate these practices adopted to physically protect the cultural asset, which rarely include the local values ascribed by the surrounding communities. This reflection motivated the development of this study that aims to examine the social valuation ascribed to protected railway assets on the route Jundiaí-Campinas (Brazil), in order to compare the different identified values and reflect on the integrated actions of railway heritage preservation and management. To this end, a values-based approach (VBA) was used, a methodology employed for and centred on heritage preservation, which focuses on understanding the local community as one of the protagonists in the heritage valuation process. Applying the different techniques of the VBA method revealed that other values, besides the traditional ones dominant in the specialised dissemination of the subject, also have an impact on the heritage asset. By integrating these community values to the protection and management practices of the cultural asset, it is indeed possible to significantly protect and safeguard not only the monumental object but also its values.
Given the shortcomings of traditional heritage preservation practices in understanding the values that justify heritage protection, it is necessary to critically re-evaluate these practices adopted to physically protect the cultural asset, which rarely include the local values ascribed by the surrounding communities. This reflection motivated the development of this study that aims to examine the social valuation ascribed to protected railway assets on the route Jundiaí-Campinas (Brazil), in order to compare the different identified values and reflect on the integrated actions of railway heritage preservation and management. To this end, a values-based approach (VBA) was used, a methodology employed for and centred on heritage preservation, which focuses on understanding the local community as one of the protagonists in the heritage valuation process. Applying the different techniques of the VBA method revealed that other values, besides the traditional ones dominant in the specialised dissemination of the subject, also have an impact on the heritage asset. By integrating these community values to the protection and management practices of the cultural asset, it is indeed possible to significantly protect and safeguard not only the monumental object but also its values.
<p>(A) Western blot showing protein expression of AKAP-Lbc and RhoA in five different cell lines and in primary rat inner medullary collecting duct (IMCD) cells: All cells express full-length AKAP-Lbc (308 kDa) and shorter splice... more
<p>(A) Western blot showing protein expression of AKAP-Lbc and RhoA in five different cell lines and in primary rat inner medullary collecting duct (IMCD) cells: All cells express full-length AKAP-Lbc (308 kDa) and shorter splice variants. RhoA (22 kDa) is also expressed in all cells. MW = molecular weight. (B) Cytotoxicity was assessed after 24–72 h of incubation with Scaff10-8 (3, 30, 100 μM). Staurosporine as inducer of apoptosis was used as a positive control. Absorption was determined at 450 nm and was related to medium absorption (blank). DMSO was used as a control. Normalised to untreated cells after 24 h, three independent experiments with four data points each are shown. n = 3. Statistically significant differences were determined applying one-way ANOVA with posthoc Bonferroni. Mean ± SEM is plotted.</p