Clotrimazole
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Recent papers in Clotrimazole
The Pregnane X Receptor (PXR) is a nuclear receptor involved in the transcriptional regulation of drug-metabolizing enzymes and transporters. In mammals, many xenobiotics induce the expression of cytochrome P4503A (CYP3A) and the multiple... more
Clotrimazole is marketed as a regularly occurring drug under numerous distinct names and via means of numerous agencies because of its antifungal activity. Clotrimazole, an artificial imidazole derivative, is often used domestically for... more
Otomycosis due to saprophytic keratolytic fungi represents a small percentage of clinical external otitis. Although there are certain antibacterial and antifungal agents available, they usually are very caustic, potentially ototoxic and... more
This study was designed to compare the therapeutic effects of topical clotrimazole and systemic fluconazole in pityriasis versicolor. A double-blind randomized controlled trial was carried out in the dermatological clinic of Gorgan,... more
Background: Vaginal yeast infections (candidiasis) are among the most common gynecologic infections in women. Due to the high prevalence of vaginal candidiasis and its recurrence, followed by such chemical treatment as Clotrimazole, this... more
Eight new ruthenium complexes of clotrimazole (CTZ) with high antiparasitic activity have been synthesized, cis,fac-[Ru(II)Cl(2)(DMSO)(3)(CTZ)] (1), cis,cis,trans-[Ru(II)Cl(2)(DMSO)(2)(CTZ)(2)] (2), Na[Ru(III)Cl(4)(DMSO)(CTZ)] (3),... more
Trichophyton tonsurans is an anthropophilic dermatophyte, with a worldwide distribution, although its prevalence varies considerably between different geographical regions. Whereas in North America infections due to this fungus are... more
Two sensitive, accurate, and precise spectrophotometric methods have been developed and validated for the simultaneous estimation of ofloxacin (OFX), clotrimazole (CLZ), and lignocaine hydrochloride (LGN) in their combined dosage form... more
A simple route for synthesizing tetrahydro-6-methylpyrimidine-one and – thione derivatives by condensation reaction of chloroquinolinecarbaldehyde. β-dicarbonyl compounds, as ethylacetoacetate or oracetylacetone and urea or thiourea in... more