NIMODIPINE
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Recent papers in NIMODIPINE
BACKGROUND AND OBJECTIVE Anxiety that occurs during alcohol withdrawal may be the precipitating factor for relapse of alcoholism. Earlier studies have demonstrated calcium channel activity peaks during alcohol withdrawal and calcium... more
Despite intensive interest in under- standing the differentiation of vascular smooth mus- cle cells (VSMC), no information is available about differential regulation of ion channels in these cells. Since expression of the L-type Ca2/... more
Endocrine disrupters (EDs) continue to be the focus of extensive research. Their effects and mode of action as well as their occurrence and fate in the aquatic environment are still largely unknown and need investigation. Wastewater... more
Delayed ischemic neurologic deficit (DIND) is a serious complication of acute aneurysmal subarachnoid hemorrhage (aSAH). Although oral nimodipine is accepted as standard care for the prevention of DIND, the intravenous route is preferred... more
Endocrine disrupters (EDs) continue to be the focus of extensive research. Their effects and mode of action as well as their occurrence and fate in the aquatic environment are still largely unknown and need investigation. Wastewater... more
We have recently synthesized a new series of hybrid compounds having the moieties of tacrine, a potent inhibitor of brain and peripheral acetylcholinesterase (AChE), and nimodipine, a blocker of L-type voltage-dependent calcium channels... more
Comparison between evolutionarily distant receptors can provide critical insights into both structure and function. Sequence comparison between the mineralocorticoid receptors (MR) of the zebrafish (zMR) and human (hMR) reveals a high... more
In the present study, the effects on intracellular calcium concentration ([Ca(2+)](i)) oscillations of the blockade of ether-a-go-go-related gene (ERG) K(+) channels and of Ca(2+) influx through store-operated channels (SOC) activated by... more
Calcium plays an important role in the pathophysiology of pain. A number of studies have investigated the effect of L-type calcium channel blockers on the analgesic response of morphine. However, the results are conflicting. In the... more