Neutrophil extracellular traps
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Recent papers in Neutrophil extracellular traps
Autoimmune and autoinflammatory diseases have dramatically increased in both developed and developing countries. The etiology of these diseases is complex and developed due to multifactorial causes. It is tought that autoantigens are the... more
As a strong heritability component has recently been identified in a whole exome sequencing study in SARS-CoV-2 infected COVID-19 patients, the ongoing identification of host susceptibility factors appears to be a worthwhile endeavour. In... more
Pathogens hide immunogenic epitopes from the host to evade immunity, persist and cause infection. The opportunistic human fungal pathogen Candida albicans, which can cause fatal disease in immunocompromised patient populations, offers a... more
ABSTRACT—Sepsis is characterized by systemic activation of coagulation and inflammation in response to microbial infection. Although cell-free DNA (cfDNA) released from activated neutrophils has antimicrobial properties, it may also exert... more
Oxygen deprivation and infection are major causes of perinatal brain injury leading to cerebral palsy and other neurological disabilities. The identification of novel key factors mediating white and grey matter damage are crucial to allow... more
Neutrophil extracellular traps (NETs) are chromatin filaments released by activated polymorphonuclear neutrophils (PMNs) and decorated with granule proteins with various properties. Several lines of evidence implicate NETs in thrombosis.... more
Innovation in microfluidics-based biological research has been aided by the growing accessibility of versatile microscale fabrication techniques, particularly in rapid prototyping of elastomeric polydimethylsiloxane (PDMS) based devices.... more
<p>(A) Zincosome screen. Wild type, ZnT deletion mutants and <i>zrc1</i>Δ+<i>ZRC1</i> strains were pulsed with 25 μM zinc for 20 minutes and zincosome fluorescence determined by staining with zinquin.... more
Cystic fibrosis (CF) is an autosomal recessive disorder caused by mutations in the gene that codes for the CF trans-membrane conductance regulator. These mutations result in abnormal secretions viscous airways of the lungs, favoring... more
Neutrophil extracellular traps (NETs) are chromatin filaments released by activated polymorphonuclear neutrophils (PMNs) and decorated with granule proteins with various properties. Several lines of evidence implicate NETs in thrombosis.... more