How do we change the system(s) we live in ? By essence a system is an inherently complex web of relationships. Systems thinking researcher Donella Meadows has given us a map of leverage points to act on a system but there is no practical... more
How do we change the system(s) we live in ? By essence a system is an inherently complex web of relationships. Systems thinking researcher Donella Meadows has given us a map of leverage points to act on a system but there is no practical plan as to where to start effectively to trigger systemic change.
Interestingly around the late seventies, two systems thinkers/practitioners developed practical design frameworks for systems transformation.
The first framework, Permaculture, is an integrated approach to designing agro-ecological systems developed by ecological scientist Bill Mollison. Permaculture focussed initially on developing a resilient “permanent-agriculture” but it was expanded to stand also for "permanent culture," as it was seen that social aspects were integral to a truly sustainable system. Although it is still not widely recognized by either the scientific community or the general public, Permaculture has developed a very powerful set of analytical and design tools for whole systems transformation.
The second framework, Pattern Languages, was developed by architect Christopher Alexander to build human settlements and “living” architectural systems. If Alexander’s Pattern Language focusses on built structures, it also encompasses a social dimension. Although Alexander’s work hasn’t taken off in the architectural field it deeply inspired software programming and a growing number of disciplines.
Both frameworks share a common approach to systems design called patterning.
While design builds structures by assembling elements, patterning can be seen as a branch of design that builds systems by weaving relationships.
In this paper we look at the commonalities and differences between the two approaches, discuss how they could be used by systems thinking practitioners and propose Permaculture Patterning as a new framework for systems design and transformation.
Block copolymers (BCPs) and their directed self-assembly (DSA) has emerged as a realizable complementary tool to aid optical patterning of device elements for future integrated circuit advancements. Methods to enhance BCP etch contrast... more
Block copolymers (BCPs) and their directed self-assembly (DSA) has emerged as a realizable complementary tool to aid optical patterning of device elements for future integrated circuit advancements. Methods to enhance BCP etch contrast for DSA application and further potential applications of inorganic nanomaterial features (e.g., semiconductor, dielectric, metal and metal oxide) are examined. Strategies to modify, infiltrate and controllably deposit inorganic materials by utilizing neat self-assembled BCP thin films open a rich design space to fabricate functional features in the nanoscale regime. An understanding and overview on innovative ways for the selective inclusion/infiltration or deposition of inorganic moieties in microphase separated BCP nanopatterns is provided. Early initial inclusion methods in the field and exciting contemporary reports to further augment etch contrast in BCPs for pattern transfer application are described. Specifically, the use of evaporation and sputtering methods, atomic layer deposition, sequential infiltration synthesis, metal-salt inclusion and aqueous metal reduction methodologies forming isolated nanofeatures are highlighted in di-BCP systems. Functionalities and newly reported uses for electronic and non-electronic technologies based on the inherent properties of incorporated inorganic nanostructures using di-BCP templates are highlighted. We outline the potential for extension of incorporation methods to triblock copolymer features for more diverse applications. Challenges and emerging areas of interest for inorganic infiltration of BCPs are also discussed.
We simulated and experimentally investigated the formation of periodic structures generated by multibeam interference patterning. The simulations at the different setup geometry show that resulting interference pattern is... more
We simulated and experimentally investigated the formation of periodic structures generated by multibeam interference patterning. The simulations at the different setup geometry show that resulting interference pattern is quasi-periodical. The calculated patterns show that the symmetries of the interference maxima depend mostly on the angles of incidence and that a wide variety of patterns can be obtained. Because of the difficulty in aligning four beams sufficiently well to avoid secondary periodicities, for testing we used a three-beam interference configuration. Atomic force microscopy images showed good correspondence between the experimental and simulated interference image, with flat islands which correspond to the destructive interference and narrow channels which correspond to the constructive interference fringes.
Disrupted morphogenesis and growth of the embryonic maxillary jaw leads to oral facial clefting in humans (OFC) and results in an incompletely formed secondary mouth and face. A requirement for Wnt signaling and Wnt9b in particular are... more
Disrupted morphogenesis and growth of the embryonic maxillary jaw leads to oral facial clefting in humans (OFC) and results in an incompletely formed secondary mouth and face. A requirement for Wnt signaling and Wnt9b in particular are postulated in the etiology of OFC from association studies in humans and from animal models. Loss of murine Wnt9b leads to reduced upper jaw (maxillary) outgrowth and OFC, though the signaling architecture leading to this phenotype is poorly understood. Previous murine Wnt9b studies largely overlooked cranial neural crest cell (CNCC) patterning events and instead focused on later events during fusion of facial prominences. Using zebrafish and a morpholino-mediated knockdown approach, we demonstrate functional requirements for Wnt9b signaling during two crucial stages of facial development: 1) CNCC patterning into Dorsal-Intermediate-Ventral (D-I-V) domains; and 2) facial outgrowth during the primary to secondary mouth transition (PM to SM). Zebrafish embryos deficient for Wnt9b (Wnt9b morphants) exhibit an open bite with fused jaw joints as well as a flat face. Open bite and jaw joint fusion in Wnt9b morphants phenocopies characteristics of edn1 pathway is mutant zebrafish with disrupted D-I-V patterning of CNCC. Expression studies show Wnt9b morphants exhibit perturbed expression of edn1 signaling targets including dlx2a, jag1b, and msxe, consistent with disrupted CNCC patterning. Wnt9b morphant upper jaws have stunted outgrowth reminiscent of murine Wnt9b mutants and Wnt9b morphant skulls phenocopy the broad class of foreshortened skull zebrafish mutants known as hammerheads. Wnt9b morphants show upregulated expression of pitx2a after the opening of the primary mouth and disrupted expression of Wnt5b which is consistent with disrupted chondrocyte stacking. Strong upregulation of dorsal mesodermal frzb expression in the prechordal plate of Wnt9b morphants suggests a role for Wnt9b in primary mouth induction or maintenance. Collectively these results argue that Wnt9b has a much earlier developmental requirement. This work draws attention to potential vertebrate homologies that pattern CNCC and facial outgrowth and therefore calls for a reexamination of Wnt9b’s role during mammalian craniofacial development.
Important aspects of human cognition are considered in terms of patterning, a key factor in the development of human cognition and culture, which also represents a shift from focusing on what is present to what is absent. We make use of... more
Important aspects of human cognition are considered in terms of patterning, a key factor in the development of human cognition and culture, which also represents a shift from focusing on what is present to what is absent. We make use of Deacon's (2012) notion of absentials with which he understands the emergence of life and sentience from abiotic matter. Logan and Tandoc's (2018) assertion that the patterning that underscores human cognition is reexamined in terms of Deacon's absentials. Several important aspects of human cognition are considered that represent a shift from focusing on what is present to what is absent, namely, language as representing the transition from percept to concept-based thinking (Logan 2007), mathematical grouping and patterning of items into sets (Logan & Pruska-Oldenhof 2018) that gave rise to verbal language as well as imaginative thinking so critical for the development of the arts, mathematics and science. The connection between information and absence is also examined in which we claim that information is an absential paralleling an idea of Deacon's. There is more here than stuff. There is how this stuff is organized and related to other stuff-Terrence Deacon The spoken word was the first technology by which man was able to let go of his environment in order to grasp it in a new way-Marshall McLuhan
Children’s engagement with algebraic thinking has traditionally commenced in senior primary or secondary school, preceded by primary school curricula that prioritised computation and understandings of number (Kieran, et al., 2016).... more
Children’s engagement with algebraic thinking has traditionally commenced in senior primary or secondary school, preceded by primary school curricula that prioritised computation and understandings of number (Kieran, et al., 2016). Increasingly during the latter decades of the 20th century, educators and researchers identified that such an approach may contribute to insurmountable challenges for some children when they first encounter formal algebra, typically after six to eight years of school. In this paper I present the research underpinning the Early Algebra movement that arose from a motivation to address such challenges, and the implications of Early Algebra for the Irish Primary School Mathematics Curriculum (IPSMC). While the 1999 IPSMC included algebra as a content strand, key concepts of Early Algebra, such as generalisation, and exploration of structure, are absent (Twohill, 2013).
To date, optical lithography has been extensively used for in situ patterning of hydrogel structures in a scale range from hundreds of microns to a few millimeters. The two main limitations which prevent smaller feature sizes of hydrogel... more
To date, optical lithography has been extensively used for in situ patterning of hydrogel structures in a scale range from hundreds of microns to a few millimeters. The two main limitations which prevent smaller feature sizes of hydrogel structures are (1) the upper glass layer of a microchip maintains a large spacing (typically 525 μm) between the photomask and hydrogel precursor, leading to diffraction of UV light at the edges of mask patterns, (2) diffusion of free radicals and monomers results in irregular polymerization near the illumination interface. In this work, we present a simple approach to enable the use of optical lithography to fabricate hydrogel arrays with a minimum feature size of 4 μm inside closed microchips. To achieve this, we combined two different techniques. First, the upper glass layer of the microchip was thinned by mechanical polishing to reduce the spacing between the photomask and hydrogel precursor, and thereby the diffraction of UV light at the edges of mask patterns. The polishing process reduces the upper layer thickness from ∼525 to ∼100 μm, and the mean surface roughness from 20 to 3 nm. Second, we developed an intermittent illumination technique consisting of short illumination periods followed by relatively longer dark periods, which decrease the diffusion of monomers. Combination of these two methods allows for fabrication of 0.4 × 106 sub-10 μm sized hydrogel patterns over large areas (cm2 ) with high reproducibility (∼98.5% patterning success). The patterning method is tested with two different types of photopolymerizing hydrogels: polyacrylamide and polyethylene glycol diacrylate. This method enables in situ fabrication of well-defined hydrogel patterns and presents a simple approach to fabricate 3-D hydrogel matrices for biomolecule separation, biosensing, tissue engineering, and immobilized protein microarray applications.
Children’s engagement with algebraic thinking has traditionally commenced in senior primary or secondary school, preceded by primary school curricula that prioritised computation and understandings of number (Kieran, et al., 2016).... more
Children’s engagement with algebraic thinking has traditionally commenced in senior primary or secondary school, preceded by primary school curricula that prioritised computation and understandings of number (Kieran, et al., 2016). Increasingly during the latter decades of the 20th century, educators and researchers identified that such an approach may contribute to insurmountable challenges for some children when they first encounter formal algebra, typically after six to eight years of school. In this paper I present the research underpinning the Early Algebra movement that arose from a motivation to address such challenges, and the implications of Early Algebra for the Irish Primary School Mathematics Curriculum (IPSMC). While the 1999 IPSMC included algebra as a content strand, key concepts of Early Algebra, such as generalisation, and exploration of structure, are absent (Twohill, 2013).
Patterns are a fundamental component of mathematics, and the patterning ability of young children has been well researched; however, this research has largely been conducted with relatively small cohorts (+/- 70) and in an interventionist... more
Patterns are a fundamental component of mathematics, and the patterning ability of young children has been well researched; however, this research has largely been conducted with relatively small cohorts (+/- 70) and in an interventionist way (in laboratory settings or with researchers directly intervening in educational contexts). The current study examines the patterning skills of approximately3 200 children in a naturalistic setting. As part of a larger, early years’ STEM engagement program, children were provided patterning opportunities across one school term. The data presented here relates to the children’s performance on the tablet-based activities embedded in the program. Findings indicate that 3 to 4 year old children were able to copy, extend, insert missing elements, fix, and create patterns, using a range of two, three or four elements pattern structures. These findings, from a large-scale naturalistic setting, confirm some aspects of the existing laboratory-based research, whilst also indicating that some children are more capable in terms of creating patterns than the existing research suggests. These findings have implications for educators when they are planning play-based patterning activities with preschool children.
The formation of coffee-ring deposits upon evaporation of sessile droplets containing mixtures of poly(diallyldimethylammonium chloride) (PDADMAC) and two different anionic surfactants were studied. This process is driven by the Marangoni... more
The formation of coffee-ring deposits upon evaporation of sessile droplets containing mixtures of poly(diallyldimethylammonium chloride) (PDADMAC) and two different anionic surfactants were studied. This process is driven by the Marangoni stresses resulting from the formation of surface-active polyelectrolyte–surfactant complexes in solution and the salt arising from the release of counterions. The morphologies of the deposits appear to be dependent on the surfactant concentration, independent of their chemical nature, and consist of a peripheral coffee ring composed of PDADMAC and PDADMAC–surfactant complexes, and a secondary region of dendrite-like structures of pure NaCl at the interior of the residue formed at the end of the evaporation. This is compatible with a hydrodynamic flow associated with the Marangoni stress from the apex of the drop to the three-phase contact line for those cases in which the concentration of the complexes dominates the surface tension, whereas it is r...
Anisotropic orientation and accurate positioning of neural cells is achieved by patterning stripes of the extracellular matrix protein laminin on the surface of polystyrene tissue culture dishes by micromoulding in capillaries (MIMICs).... more
Anisotropic orientation and accurate positioning of neural cells is achieved by patterning stripes of the extracellular matrix protein laminin on the surface of polystyrene tissue culture dishes by micromoulding in capillaries (MIMICs). Laminin concentration decreases from the entrance of the channels in contact with the reservoir towards the end. Immunofluorescence analysis of laminin shows a decreasing gradient of concentration along the longitudinal direction of the stripes. The explanation is the superposition of diffusion and convection of the solute, the former dominating at length scales near the entrance (characteristic length around 50 μm), the latter further away (length scale in excess of 900 μm). These length scales are independent of the channel width explored from about 15 to 45 μm. Neural cells are randomly seeded and selectively adhere to the pattern, leaving the unpatterned areas depleted even upon 6 days of incubation. Cell alignment was assessed by the orientation...