Prostate Biopsy
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Recent papers in Prostate Biopsy
Objective: In this study, it was aimed to investigate the success of transperineal multiparametric magnetic resonance imaging (mp-MRI)/ transrectal ultrasonography (USG) fusion prostate biopsy method in prostate cancer diagnosis and... more
Objective: In this study, it was aimed to investigate the success of
transperineal multiparametric magnetic resonance imaging (mp-MRI)/
transrectal ultrasonography (USG) fusion prostate biopsy method in
prostate cancer diagnosis and detection of clinically significant cancer.
Materials and Methods: All patients signed written informed consent
then patients with an indication for prostate cancer, therefore biopsy
was planned for the last year underwent 3 Tesla mp-MRI retrospectively.
All the lesions of patients with Prostate Imaging, Reporting and Data
System (PIRADS) 3, 4 and 5 lesions were marked using MIM™ Symphony
software by a single radiologist. All patients underwent transperineal
MRI/USG fusion biopsy under general anesthesia. In the prostate MRI
evaluation of the targeted lesions with a PIRADS score of 3-4-5 were
sampled with 2 to 5 cores followed by random biopsies of both of the
prostate lobes.
Results: Prostate adenocarcinoma was diagnosed in 20 of 59 patients
(33.8%) having fusion biopsy. No difference was observed in prostatespecific
antigen levels of patients whose biopsy results were benign
and malignant. In 63% of patients, only PIRADS 3 lesions were found,
whereas PIRADS 4 and/or 5 lesions were reported in 22 (37%) patients.
The fusion biopsy of PIRADS 3 lesions revealed cancer in 7 patients
(19%), of which 6 had clinically-insignificant prostate cancer criteria.
Adenocarcinoma was diagnosed in 59% who had PIRADS 4 and/or 5
lesions. All these tumors had clinically-significant cancer characteristics.
Lesion-targeted fusion biopsies missed 1 clinically-insignificant
adenocarcinoma (1/7; 14.3%), while it did not miss any of the clinicallysignificant
cancers. No infection was seen in post-operative period. Acute
urinary retention was developed in 4 patients (6%).
transperineal multiparametric magnetic resonance imaging (mp-MRI)/
transrectal ultrasonography (USG) fusion prostate biopsy method in
prostate cancer diagnosis and detection of clinically significant cancer.
Materials and Methods: All patients signed written informed consent
then patients with an indication for prostate cancer, therefore biopsy
was planned for the last year underwent 3 Tesla mp-MRI retrospectively.
All the lesions of patients with Prostate Imaging, Reporting and Data
System (PIRADS) 3, 4 and 5 lesions were marked using MIM™ Symphony
software by a single radiologist. All patients underwent transperineal
MRI/USG fusion biopsy under general anesthesia. In the prostate MRI
evaluation of the targeted lesions with a PIRADS score of 3-4-5 were
sampled with 2 to 5 cores followed by random biopsies of both of the
prostate lobes.
Results: Prostate adenocarcinoma was diagnosed in 20 of 59 patients
(33.8%) having fusion biopsy. No difference was observed in prostatespecific
antigen levels of patients whose biopsy results were benign
and malignant. In 63% of patients, only PIRADS 3 lesions were found,
whereas PIRADS 4 and/or 5 lesions were reported in 22 (37%) patients.
The fusion biopsy of PIRADS 3 lesions revealed cancer in 7 patients
(19%), of which 6 had clinically-insignificant prostate cancer criteria.
Adenocarcinoma was diagnosed in 59% who had PIRADS 4 and/or 5
lesions. All these tumors had clinically-significant cancer characteristics.
Lesion-targeted fusion biopsies missed 1 clinically-insignificant
adenocarcinoma (1/7; 14.3%), while it did not miss any of the clinicallysignificant
cancers. No infection was seen in post-operative period. Acute
urinary retention was developed in 4 patients (6%).
- by Bora Ozveren and +1
- •
- Prostate Cancer, Prostate Biopsy
This paper describes the design of a modular robotic surgical manipulator under magnetic resonance imaging (MRI) guidance. This modular robotic manipulator primarily built up with dielectric materials, utilizes parallel mechanism and is... more
This paper describes the design of a modular robotic surgical manipulator under magnetic resonance imaging (MRI) guidance. This modular robotic manipulator primarily built up with dielectric materials, utilizes parallel mechanism and is compact in size to fit into the limited space of close-bore MRI scanner. Moreover, it provides 2 degree of freedom (DOF) Cartesian motion and 2-DOF pitch and yaw motion. It is ideal for needle based surgical procedures which usually requires positioning and orientation control for accurate imaging plane alignment. This mechanism is easily reconfigurable to provide 2-DOF Cartesian motion by simple structure modification. This modular manipulator integrated with different end-effector modules is investigated for prostate brachytherapy and neurosurgery applications as preliminary evaluation.
Objetivos: La detección del cáncer de próstata requiere una biopsia prostática para su confirmación histopatológica. Actualmente, las biopsias prostáticas por vía transrectal guiadas por ecografía (BpTR) son el procedimiento de elección,... more
Objetivos: La detección del cáncer de próstata requiere una biopsia prostática para su confirmación histopatológica. Actualmente, las biopsias prostáticas por vía transrectal guiadas por ecografía (BpTR) son el procedimiento de elección, mientras que las biopsias prostáticas por vía transperineal (BpTP) han sido usualmente recomendadas para rebiopsias de pacientes con biopsias previas negativas. El objetivo de este estudio es comparar los resultados y complicaciones postoperatorias obtenidos utilizando ambas técnicas y la efectividad para hallar tumores con score de Gleason ≥ a 7. Materiales y métodos: Se realizó un estudio retrospectivo, analizando todas las biopsias prostáticas realizadas en el servicio de urología del Hospital Alemán de Buenos Aires, en un período comprendido entre el año 2011 y 2016. Los pacientes fueron divididos en cuatro grupos. El primer grupo fue el cual pertenecían aquellos pacientes a los cuales se les realizó una BpTR sin resonancia magnética prostática previa (RMNp). El segundo grupo lo formaron aquellos pacientes a los cuales se les realizó una RMNp, previa a la BpTR, donde se practicó una biopsia standard, asociada a una biopsia del área sospechosa. dirigida por estimación visual. El tercer grupo corresponde a aquellos pacientes donde se realizó una BpTP con RMNp previa. Por último, el cuarto grupo agrupó a los pacientes que fueron sometidos a una BpTP sin RMNp previa. Se puso especial interés en la capacidad de hallar tumores con un score de Gleason ≥ a 7. A su vez, se evaluaron la tasa de complicaciones postoperatorias (ITU y RAO. Resultados: Se compararon las vías de abordaje, enfrentando los resultados obtenidos de BpTP frente a BpTR, tanto si presentaban o no RMNp previa. En primer lugar, los resultados obtenidos entre BpTR sin RMNp y BpTP sin RMNp. Se calculó Chi 2 (X²) de 8,77, con un resultado de p=0,003 (estadísticamente significativa). Por último, se comparó aquellos pacientes con RMNp previa, es decir BpTP y BpTR con RMNp. Se volvió a calcular Chi 2 (X²) de 4,6032, con un resultado de p = 0,003. En cuanto a las complicaciones postoperatorias, el grupo de pacientes sometidos a una BpTP presentó menor porcentaje de ITU o RAO, y al comparar estadísticamente estos valores, fue estadísticamente significativo (p=0,0247) cuando se evaluaron las ITU de ambos grupos. Conclusiones: En este estudio retrospectivo las biopsias prostáticas por vía transperineal permitieron hallar un número significativamente mayor de tumores prostáticos con score de Gleason ≥ a 7 que el abordaje transrectal, con o sin RMNp previa. En cuanto a las complicaciones postoperatorias, las BpTP presentaron un menor porcentaje, siendo significativas cuando se compararon las infecciones del tracto urinario. PALABRAS CLAVE: Biopsias prostáticas, tumores prostáticos. Objectives: Currently, the transrectal ultrasound-guided prostate biopsies (TRUS) are the standard-procedure, while transperineal prostatic biopsies (TP) have usually been recommended for re-biopsies of patients with previous negative biopsies. The aim of this study is to compare the results and postoperative complications obtained using both techniques and the effectiveness to find tumors with a Gleason score ≥7. Materials and methods: A retrospective study was carried out, analyzing all the prostatic biopsies performed in the Urology Service of the Hospital Aleman, between 2011 and 2016. The patients were divided into four groups. The first and second group were those patients in whom a TRUS biopsy was performed without a previous multiparametric magnetic resonance of the prostate (mp-MRI) and those who underwent a mp-MRI before the TURS-biopsy (guided by visual estimation), respectively. The third and fourth group were those patients where a TP-biopsy with previous and without mp-MR, respectively. Special interest was placed on the ability to find tumors with a Gleason score ≥7. Furthermore, the rate of postoperative complications (urinary tract infections and acute urinary retention) were evaluated. Results: The approaches were compared, comparing the results obtained with TRUS and TP biopsies, whether or not they had previous mp-MRI. First, the results obtained between TRUS-biopsy without mp-MRI and TP-biopsy without mp-MRI. Chi 2 (X²) of 8.77 was calculated, with a result of p=0.003 (statistically significant). Finally, we compared those patients with previous mp-MRI. It was recalculated Chi 2 (X²) of 4.6032, with a result of p=0.003. Regarding postoperative complications, the group of patients submitted to a TP-biopsy had a lower percentage of UTI or AUR, and when statistically comparing these values, it was statistically significant (p=0.0247) when the UTIs of both groups were evaluated. Conclusions: In this retrospective study, transperineal prostatic biopsies allowed to find a significantly higher number of prostate tumors with a Gleason score ≥7 than the transrectal approach, with or without previous mp-MRI. Regarding the postoperative complications, the TP-biopsy presented a lower percentage, being significant when the urinary tract infections were compared.
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