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Diabetic retinopathy (DR) is the leading cause of blindness in the working-age population in the U.S. The vision-threatening processes of neuroglial and vascular dysfunction in DR occur in concert, driven by hyperglycemia and propelled by... more
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      DiabetesMedicineProtein StabilityHumans
 abstract Early detection of eye diseases can forestall visual deficiency and vision loss. There are several types of human eye diseases, for example, diabetic retinopathy, glaucoma, arteriosclerosis, and hypertension. Diabetic... more
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      OphthalmologyMedicineDiabetic RetinopathyRetinal
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    •   20  
      EndocrinologyOphthalmologyMedicineHumans
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    •   16  
      Artificial IntelligenceBiomedical EngineeringImage ProcessingMachine Learning
The effects of visible light, from short to long wavelengths, on the retina were investigated functionally and histologically. The left eyes of Sprague–Dawley albino rats (6-weeks old, n = 6 for each wavelength) were exposed to seven... more
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      GeneticsRetinaRetinalMolecular sciences
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    •   7  
      OphthalmologyMedicineRetinalOptometry and Ophthalmology
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    •   7  
      Materials EngineeringComputer ScienceArtificial IntelligenceImage segmentation
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    •   16  
      EngineeringPhysicsChemistryComputer Vision
We computationally demonstrate the one-photon phase control of retinal isomerization under conditions of low laser intensity. The calculations, utilizing the multiconfigurational time dependent Hartree method, include coupling between the... more
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      RetinalCoherent Control
Introduction Multiple sclerosis (MS) is an autoimmune disorder characterized by demyelinization, inflammation, axonal/neuronal loss and gliosis of white matter of central nervous system (CNS) with multifactorial etiology including... more
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      OphthalmologyMultiple sclerosisMedicineRetinal
To describe optical coherence tomography angiography (OCTA) reflectance artifacts secondary to retinal pigment epithelial detachment (RPED). Retrospective review. Four eyes from 4 subjects were included. Three presented with RPED and 1... more
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      OphthalmologyOptical coherence tomographyRetinal Pigment EpitheliumHumans
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    •   16  
      Cognitive SciencePsychophysicsBiologyMedicine
Macroaneurysms of the retinal arteries were found in both eyes of a patient suffering from systemic hypertension. The development of the aneurysms were related to high blood pressure attacks. Treatments with low energy laser coagulation... more
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      OphthalmologyMedicineHumansHypertension
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      Materials ScienceOptical coherence tomographyMedicineBiological Sciences
A condition in which the optic nerve inside the eye is swelled due to increased intracranial pressure is known as papilledema. The abnormalities due to papilledema such as opacification of Retinal Nerve Fiber Layer (RNFL), dilated optic... more
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      Information SystemsArtificial IntelligencePakistanMedicine
Diabetic retinopathy (DR) is the most threatening disease in the world that leads to loss of eye vision; if it is not treated properly at its early stages. The main cause of DR is due to the large amount of sugar in blood which leads to... more
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    •   11  
      Computer ScienceArtificial IntelligenceOphthalmologyNatural Language Processing
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    •   5  
      NeurosciencePsychologyRetinaRetinal
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      MyopiaDopamineCircadian RhythmFemale
The aim of this study is to analyze the yield of retinal images obtained in a rural diabetes eye care model. An analysis of a sample of nonmydriatic fundus photography (NMFP) of posterior segment ophthalmic images, obtained by an... more
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      OphthalmologyMedicineIndiaHumans
To establish the dose of subretinal sodium iodate (NaIO3) in order to create a toxin-induced large animal model of selective circumscribed atrophy of outer retinal layers, the retinal pigment epithelium (RPE), and photoreceptors, by... more
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      OphthalmologyBiomarkersImmunohistochemistryOptical coherence tomography
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      OphthalmologyOptical coherence tomographyMedicineRetina
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      OphthalmologyImmunologyMedicineRetinal
Purpose To evaluate the retinal vascular response to hyperoxia in patients with diabetes at the preclinical stage of diabetic retinopathy (DR) and to quantify the changes in comparison with normal subjects using optical coherence... more
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      OphthalmologyMedicineDiabetes mellitusDiabetic Retinopathy
The circadian clock is thought to adjust retinal sensitivity to ambient light levels, yet the involvement of specific clock genes is poorly understood. We explored the potential role of the nuclear receptor subfamily 1, group D, member 1... more
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      NeurosciencePhysiologyBiologyMedicine
To study the relationship between retinal nerve fiber layer (RNFL) thickness and brain atrophy using magnetic resonance imaging (MRI) with bicaudate ratio (BCR) in patients with multiple sclerosis (MS) with different levels of disease... more
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      Multiple sclerosisMagnetic Resonance ImagingOptical coherence tomographyMedicine
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      OphthalmologyOptical coherence tomographyMedicineMacular Degeneration
CLINICAL RELEVANCE Obesity has become one of the most important health problems of today with its increasing prevalence. With the development of retinal imaging systems, obesity has been observed to be associated with changes in outer... more
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      OphthalmologyOptical coherence tomographyMedicinePhysical sciences
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      NeurosciencePhysiologyChemistryMedicine
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      ChemistryNutritionRetinal Pigment EpitheliumPigment
Macroaneurysms of the retinal arteries were found in both eyes of a patient suffering from systemic hypertension. The development of the aneurysms were related to high blood pressure attacks. Treatments with low energy laser coagulation... more
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    •   11  
      OphthalmologyMedicineHumansHypertension
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    •   13  
      OphthalmologyMyopiaHumansFemale
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      OphthalmologyOptical coherence tomographyMedicineFourier Analysis
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      OphthalmologyOptical coherence tomographyMedicineRetinitis pigmentosa
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      OphthalmologyBlindnessMedicineRetinal Pigment Epithelium
The trajectory of retinal projections and the location of retinorecipient nuclei in the quail brain was examined after application of horseradish peroxidase (HRP) either to the cut end of the optic nerve or following intraocular injection... more
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      Visual NeuroscienceBiologyMedicineBrain
Purpose To report the clinical and electrophysiological features of cone dystrophy with supernormal rod response (CDSRR). Methods Retrospective cohort study of 15 unrelated patients (nine males and six females, median age 16, range... more
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      OphthalmologyRetinaRetinalClinical Sciences
Diabetic retinopathy (DR) is one of the diseases that cause blindness globally. Untreated accumulation of fat and cholesterol may trigger atherosclerosis in the diabetic patient, which may obstruct blood vessels. Retinal fundus images are... more
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    •   7  
      Computer ScienceArtificial IntelligenceImage segmentationApplied Sciences
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      Cell BiologyRetinal Pigment EpitheliumRetinaRetinal
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      OphthalmologyMedicineBiochipRetinal
A major complication of hypertension is microvascular damage and capillary rarefaction is a known complication of hypertensive end-organ damage which confers a higher risk of systemic disease such as stroke and cardiovascular events. Our... more
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      Optical coherence tomographyMedicineRetinaloptical coherence tomography angiography
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      Retinitis pigmentosaRetinaRetinal
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      EngineeringPhysical sciencesRetinalCHEMICAL SCIENCES