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Antimicrobial Activity of Crinum defixum Ker - Gawler Leaves

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Abstract:

Crinum defixum Ker - Gawler is a bulbous herb which has widely used in indigenous medicine for many diseases; mainly leaf and bulb extracts are of medicinal importance. Leaf extract is used as a treatment for pimples, body-ache, dropsy, carbuncle, paronychia, leprosy, fever and diarrhoea. The bulbs are crushed and applied on to piles and itching. The present study to determine the possible phytochemicals and antimicrobial activity of various leaf extracts of Crinum defixum Ker - Gawler plant. The phytochemical screening demonstrated the presence different types compound like flavonoids, tannins, phenolic compounds, saponins and glycosides. The ethanol, methanol and crude extracts of Crinum defixum Ker - Gawler showed significant antibacterial activity against Escherichia coli, Staphylococcus aureus, pseudomonas aeruginosa, proteus vulgaris and antifungal activity against Candida albicans, Aspergillus flavus when compare to different concentrations (μg/mL). The antimicrobial potential of test compounds was determined on the basis of mean diameter of zone of inhibition around the disk in millimetres. Thus, the present findings revealed the medicinal potential of Crinum defixum Ker - Gawler to develop a drug against various human ailments.

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8-15

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Online since:

September 2015

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[1] Thomson GE, Further consideration of Asian Medicinal plants in treating common chronic disease in West. Journal of medicinal plants research, 4 (2) (2010) 125.

Google Scholar

[2] Bibitha B, Jisha VK, Salitha CV, Mohan S, Valsa AK. Antibacterial activity of different plant extracts. Short Communication. Indian J Microbiol 2002; 42: 361-363

Google Scholar

[3] Maghrani, M.; Zeggwah, N.;Michel, J. and Eddouks, M. Antihypertensive effect of Lepidium sativum in spontaneously hypertensive rats. J Ethnopharm 2005; 102 (1-2); 193 – 197

DOI: 10.1016/j.jep.2005.02.024

Google Scholar

[4] Uniyal, S.K., K.N. Singh, P. Jamwal and B. Lal, 2006. Traditional use of medicinal plants among the tribal communities of chhota Bhangal, Western Himalayan.

DOI: 10.1186/1746-4269-2-14

Google Scholar

[5] J. Ethnobiol. Ethnomed., 2: 1 – 14.

Google Scholar

[6] Tram NTN, Titorenkova TV, Bankova VS, Handjieva NV, Popov SS. Crinum L. (Amaryllidaceae). Fitoterapia, 2002; 73: 183 – 208

DOI: 10.1016/s0367-326x(02)00068-0

Google Scholar

[7] Hooker JD, Flora of British India, Published under the authority of the Secretary of state for India in Council, (1954)

Google Scholar

[8] K.R. Kirtikar, B,D. Basu, Indian Medicinal Plants, vol. IV (1975) Published by M/S Bishen Singh Mohendra Pal Sing, New Connaught Place, Dehradun, PP. 2473 – 2474.

Google Scholar

[9] H.G, Boit, W. Dopke, W. Stender, Chem. Ber. 90 (1957) 2203.

Google Scholar

[10] P.W. Jeffs, A. Abou – Donia, D. Campau, D.D. Staiger, J. Org. Chem. 50 (1985) 1732 – 1737.

Google Scholar

[11] Ashis KM, Susanta K, Ranjan BP, Upndranath N. Free radical scavenging and analgesic properties of the bulb of crinum defixum ker gawl on experimental animal model. Int J Bio & Pharm Res 2010; 1 (2): 82 – 87.

Google Scholar

[12] Shilpa K, Harish Chandra R, Krishnaveni B. Anti – inflammatory Activity of crinum defixum ker – gawl. Int J Pharm Sci and Drug Res 2012; 4 (2): 147 – 149.

Google Scholar

[13] Tona, L., K. Kambu, N. Ngimbi, K. Cimanga and A.J. Vlietinck, 1998. Antiamoebic and phytochemical screening of some Congolese medicinal plants. J. Ethnopharmacol., 61: 57 – 65.

DOI: 10.1016/s0378-8741(98)00015-4

Google Scholar

[14] Samy, R.P. and S. Ignacimuthu, 2000. Antibacterial activity of some folklore medicinal plants used by tribals in Western Ghats in India. J. Ethnopharmacol., 69: 63 – 71.

DOI: 10.1016/s0378-8741(98)00156-1

Google Scholar

[15] Palombo, E.A. and S.J. Semple, 2001. Antibacterial activity of traditional medicinal plants. J. Ethnopharmacol., 77: 151 – 157.

Google Scholar