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Journal / Neuroscience / Optogenetic Functional MRI
JoVE Journal
Neuroscience

This content is Open Access.

JoVE Journal Neuroscience
Optogenetic Functional MRI
 

Optogenetic Functional MRI

Article DOI: 10.3791/53346-v • 06:06 min • April 19th, 2016
April 19th, 2016 •
1, 2, 1, 1,2
1Neurology and Neurological Sciences, Stanford University, 2Electrical Engineering, Neurology and Neurological Sciences, Stanford University

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Summary
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This protocol describes the steps and data analysis required to successfully perform optogenetic functional magnetic resonance imaging (ofMRI). ofMRI is a novel technique that combines high-field fMRI readout with optogenetic stimulation, allowing for cell type-specific mapping of functional neural circuits and their dynamics across the whole living brain.

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Keywords: Optogenetic Functional MRI Cell-type-specific Neural Circuits Brain Activity Neuroscience Stereotaxic Craniotomy Microliter Syringe Vector Ferrule Implant Dental Cement Fiberoptic Patch Cable Laser Light Source Power Meter Coil Scanner
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