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A glaring gap in the portfolio of reactions used to synthesize libraries of organic compounds has been filled by the advent of a general method for joining together 3D molecular fragments â a boon for pharmaceutical research.
Considerable uncertainties surround whether and how Earth could bounce back from a transgression of the temperature limits agreed in Paris. An analysis of overconfidence in models suggests that it might be safer to avoid such a path.
The race is on to find interventions that improve health and promote longevity. The mechanisms behind and possible benefits of one such intervention, dietary restriction, are more complex than previously thought.
The jury has been out on whether global warming will increase the erosion of riverbanks in the Arctic â with consequences for human infrastructure and the environment. A detailed analysis of an Alaskan river suggests that it will.
What is the neural basis of our perceptual experience? Simultaneous recordings from many individual neurons in humans provide surprising insights into how odours are processed in different regions of the brain.
Migrating animals can bring food and contaminants to their destination. An assessment of Pacific salmon migrations from 1976 to 2015 reveals changes in the scale of this coupled transport and potential effects for consumers.
Lynx numbers ebb and flow as these predators hunt hares across Alaska, but analysis suggests that this population wave is mediated by survival rather than by how lynx disperse.
Dinosaur bones found on the shores of an African Great Lake, and unintentional explosions get Londonâs birds into a flap, in our weekly dip into Natureâs archive.
Abnormal filaments of a single type of protein are hallmarks of neurodegeneration. Structural studies reveal filaments made from two discrete but interwoven proteins, giving clues about the origin of neurodegenerative conditions.
Neuroscientists have reconstructed the first complete wiring map of the fruit-fly brain, including 140,000 neurons and more than 50 million connections. This resource has already begun to revolutionize the field.
Aircraft observations of high-energy rays emitted by thunderstorms reveal that they are both intense and dynamic. Long-lasting glows that switch to rapidly flickering flashes could offer clues to how lightning forms.
Mammals feed using a jaw hinge formed by dentary and squamosal bones. Fossil evidence reveals that this type of joint evolved independently in an extinct species of mammalian relatives called cynodonts.
An in-depth investigation of gene regulation and cell populations at sites of fetal blood-cell production provides clues as to why children with Downâs syndrome are predisposed to developing leukaemia.
If a cell can diversify its own genome, this can be advantageous in the face of changing environmental conditions. Bacteria have been found that can alter encoded proteins by using the trick of sequence inversion inside genes.
An undersea cable promises to improve Britainâs relationship with Europe, and a poetâs attempt at ornithology is debunked, in Natureâs weekly step back in time.
Can cycles of dieting increase your risk of heart attack? In mice, an alternating high-fat and low-fat diet promotes plaque build-up in arteries by modulating the bodyâs innate immune responses.
JWST has opened a window on exoplanet imaging by observing the planet ε Indi Ab directly. The planetâs existence had been inferred, but its age and temperature made the discovery difficult to confirm â until now.
By smashing protons together at blinding speeds, scientists have shown that pairs of quarks display the phenomenon of quantum entanglement. The result could lead to fresh insight about one of the forces holding nuclei together.