Renal fibrosis articles from across Nature Portfolio

Fibrosis has a key role in the progression of kidney disease and kidney failure. Here, the authors examine current options for targeting pro-fibrotic pathways, including the anti-fibrotic potential of nephroprotective drugs, as well as technological advances that might improve kidney fibrosis outcomes.

Progression of chronic kidney disease to kidney fibrosis is a key challenge in nephrology. Several contributions from the past year have shed light not only on the general molecular signature of human kidney fibrosis, but also on specific new mechanisms involved in its development.