AbstractFollowing the example of several countries, the Kingdom of Morocco adopted, in the middle of the twentieth century, nuclear techniques in the medical and industrial fields, which have experienced a greater and sustained growth following its membership of the IAEA in 1957. This chapter presents the evolution of the nuclear and radiological infrastructure in Morocco over the last 60 years and the prospects for its future development. The chapter outlines the continuous efforts made by public authorities to upgrade the national nuclear and radiological regulatory framework in compliance with international obligations related to safety, security and safeguards. In this regard, the Moroccan Agency for Nuclear and Radiological Safety and Security (AMSSNuR) has, since its inception, been driven by the will and ambition to achieve its vision of establishing itself at the national level as an independent, effective, credible and transparent regulatory body; as well as a leader at the African level and significant contributor in the international arena. The Moroccan experience in safety and security governance and management is highlighted, and the lessons learned and experience gained in this area by AMSSNuR are shared.