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Substantial evidence from experimental studies has shown that mating motivation increases men’s financial risk-taking behaviors. The present study proposed a new moderator, men’s past relationship experience, for this well-accepted link between mating motivation and financial risk-taking tendency. Heterosexual young men were randomly assigned to the mating condition and control condition, and they completed a set of financial risk-taking tasks and reported their past relationship experience. A significant main effect of mating motivation and a significant interaction effect between experimental conditions (mating group and control group) and relationship experience emerged, suggesting that mating motivation increased financial risk-taking tendency only among men who have never been committed in a romantic relationship, rather than those who have had such experience. This moderating effect was replicated in two experiments. The present study contributed to the understanding of individual differences in the relationship between mating motivation and male financial risk-taking. The present findings also have important implications for financial industry and gambling companies to better target clients and advertise their high-risk products.

AbstractThe schweinfurthin family of natural compounds exhibit a unique and potent differential cytotoxicity against a number of cancer cell lines and may reduce tumor growth in vivo. In some cell lines, such as SF-295 glioma cells, schweinfurthins elicit cytotoxicity at nanomolar concentrations. However, other cell lines, like A549 lung cancer cells, are resistant to schweinfurthin treatment up to micromolar concentrations. At this time, the precise mechanism of action and target for these compounds is unknown. Here, we employ RNA sequencing of cells treated with 50 nM schweinfurthin analog TTI-3066 for 6 and 24 h to elucidate potential mechanisms and pathways which may contribute to schweinfurthin sensitivity and resistance. The data was analyzed via an interaction model to observe differential behaviors between sensitive SF-295 and resistant A549 cell lines. We show that metabolic and stress-response pathways were differentially regulated in the sensitive SF-295 cell line as compared with the resistant A549 cell line. In contrast, A549 cell had significant alterations in response genes involved in translation and protein metabolism. Overall, there was a significant interaction effect for translational proteins, RNA metabolism, protein metabolism, and metabolic genes. Members of the Hedgehog pathway were differentially regulated in the resistant A549 cell line at both early and late time points, suggesting a potential mechanism of resistance. Indeed, when cotreated with the Smoothened inhibitor cyclopamine, A549 cells became more sensitive to schweinfurthin treatment. This study therefore identifies a key interplay with the Hedgehog pathway that modulates sensitivity to the schweinfurthin class of compounds.

The aim of the study was to examine the role of self-esteem in resisting the influence of materialistic goals of four social role models (mother, father, peers, and media) in adolescents (aged 13–16). Previous studies showed a negative correlation between the psychological health of teens and striving for materialistic goals, one of the main sources is the social modeling of materialism. Two studies were carried out. The first, correlational study, was conducted on target teens and their mothers, fathers, and peers of their choice. It examined if self-esteem is a moderator of the relationship between the materialism of social role models (mothers, fathers, peers, and media) and the materialism of teens. The second, experimental study, was conducted on target teens only. It examined how boosting the self-esteem of teens and activating materialism of social role models (mothers, fathers, peers, and media) may affect the materialism of teens. Study 1 showed a significant interaction effect of self-esteem and the materialism of peers on the materialism of teens. The interaction effects of self-esteem and other role models (parents and media) were not significant. Study 2 showed that elevated self-esteem lowered the influence of the materialism of peers on the materialism of teens. The results were not significant when other role models (parents and media) were analyzed. The results obtained in the presented studies indicate that the self-esteem of teens may have an important role in resisting the influence of materialism role models of peers. Practical implications of the studies for the psychological health of teens are also discussed.

The purpose of this study was to assess the degree to which sheltered versus unsheltered contexts of introductory communication courses impact communication skill development and overall learning outcomes for international students. Specifically, this study examined the following outcome variables: public speaking anxiety, engagement, communication mindset, communication efficacy, and student performance to investigate whether it is beneficial to sheltered international students in introductory courses. Results showed that there was no significant difference between groups for the public speaking anxiety, student engagement, or overall course performance, except for the final group presentation performance. However, there was a significant interaction effect for communication mindset and communication efficacy; students in sheltered sections saw increases in these outcomes over the course of the semester, while unsheltered students experienced the opposite.

Abstract The study examined evidence of gender equity in pupils achievement in phonics, when exposed to adult and children-generated illustrations in Njikoka Local Government Area of Nigeria. The study employed a non-equivalent quasi‐experimental 2 x 2 factorial research design. Some 158 primary two pupils from 4 schools were used for the study. The English Achievement Test (EAT) was used to collect data. Three hypotheses were tested. The data were analysed using descriptive statistics and Analysis of Covariance (ANCOVA). The results showed that there was a significant main effect for the mode of illustration on pupils’ achievement in phonics F(1,153) = 21.315, p=.000; there was no significant main effect of gender F(1,153) = 1.082, p =.300, and there was no significant interaction effect of mode of illustration and gender F(1,153) = .701, p =.404. The study recommended that since the children-generated illustrations were more effective in teaching phonics and enhancing pupils achievement in phonics, the Ministries of Education should ensure that textbook authors incorporate children-generated illustrations in the instructional materials for pupils in primary schools. Mode of illustration had no differential effects on male and female pupils achievement in phonics. As such the present system of teaching both males and females in the same class should be encouraged. Authors and publishers of children’s books should engage pupils’ in illustrating their books.

AbstractThe present study examined differences in adults’ spatial-scaling abilities across three perceptual conditions: (1) visual, (2) haptic, and (3) visual and haptic. Participants were instructed to encode the position of a convex target presented in a simple map without a time limit. Immediately after encoding the map, participants were presented with a referent space and asked to place a disc at the same location from memory. All spaces were designed as tactile graphics. Positions of targets varied along the horizontal dimension. The referent space was constant in size while sizes of maps were systematically varied, resulting in three scaling factor conditions: 1:4, 1:2, 1:1. Sixty adults participated in the study (M = 21.18; SD = 1.05). One-third of them was blindfolded throughout the entire experiment (haptic condition). The second group of participants was allowed to see the graphics (visual condition); the third group were instructed to see and touch the graphics (bimodal condition). An analysis of participants’ absolute errors showed that participants produced larger errors in the haptic condition as opposed to the visual and bimodal conditions. There was also a significant interaction effect between scaling factor and perceptual condition. In the visual and bimodal conditions, results showed a linear increase in errors with higher scaling factors (which may suggest that adults adopted mental transformation strategies during the spatial scaling process), whereas, in the haptic condition, this relation was quadratic. Findings imply that adults’ spatial-scaling performance decreases when visual information is not available.

This study examined the effects of an e-mail-delivered cognitive behavioral therapy for insomnia (CBT-I), validated in Western countries, on insomnia severity, anxiety, and depression in young adults with insomnia in Eastern countries, particularly Japan. This prospective parallel-group randomized clinical trial included college students with Insomnia Severity Index (ISI) scores of ten or higher. Participants were recruited via advertising on a university campus and randomized to an e-mail-delivered CBT-I (REFRESH) or self-monitoring (SM) with sleep diaries group. The primary outcomes were insomnia severity, anxiety, and depression; secondary outcomes were sleep hygiene practices, dysfunctional beliefs, sleep reactivity, and pre-sleep arousal. All measurements were assessed before and after the intervention. A total of 48 participants (mean (SD) age, 19.56 (1.86) years; 67% female) were randomized and included in the analysis. The results of the intent-to-treat analysis showed a significant interaction effect for insomnia severity, anxiety, depression, sleep hygiene practice, and pre-sleep arousal. Compared with the SM group, the REFRESH group was more effective in reducing insomnia severity (Hedges’ g = 1.50), anxiety (g = 0.97), and depression (g = 0.61) post-intervention. These findings suggest that an e-mail-delivered CBT-I may be an effective treatment for young adults with elevated insomnia symptoms living in Japan.

Deviant behaviours are a significant cost to Canadian society and can incur an immeasurable amount of emotional and physical damage every year (Office of the Parliamentary Budget Officer, 2018; The John Howard Society of Canada, 2018). There have been numerous studies on the role of risk factors in affecting deviant behaviours, however, few of these have examined the influence of self-determination on deviance (Mann et al., 2010; Murray & Farrington, 2010; Zara & Farrington, 2010). This study intends to fill this gap by investigating the interactions between self-determination, gender, risk factors, and deviance. Participants were invited through the University of Saskatchewan’s PAWS and SONA systems to complete an online survey that asked questions relating to gender, self-determination, risk factors, and deviance. A Chi-square Test for Independence was utilized to explore the explicit relationships between the type of self-determination and gender differences. In addition, a two-way MANOVA was used to compare self-determination and gender together in relation to deviance and risk factors. A Chi-square test found that there was not a significant relationship between gender and self-determination while the two-way MANOVA found a significant interaction effect between self-determination, deviance, and risk factors. However, when the interaction was examined further through univariate ANOVAs, no significant differences were found. Future research that examines and expands on the relationship between self-determination, gender, risk factors and antisocial behavior is suggested.

Abstract The study investigated the interaction effect of mode of illustration and colour preference on pupils’ achievement in phonics in Nnobi in Idemili South Local Government Area of Nigeria. The study employed a non-equivalent quasi‐experimental 2 x 3 factorial research design. Some 167primary two pupils from 4 schools were used for the study. The English Achievement Test (EAT) was used to collect data. Three hypotheses were tested. The data were analysed using descriptive statistics and Analysis of Covariance (ANCOVA). The results showed that there was a significant main effect for the mode of illustration on pupils’ achievement in phonics F(1,165) = 123.221, p = .000; there was a significant main effect of colour preference on pupils’ achievement in phonics F (2,165) = 55.198, p = 000; and there was a significant interaction effect of illustration and colour preference on pupils’ achievement in phonics F (2,165) = 7.593, p = .001. Because the children-generated illustrations were more effective in teaching phonics and enhancing pupils achievement in phonics, the Ministries of Education should ensure that textbook author incorporate children-generated illustrations in the instructional materials for pupils in primary schools. These materials should be rendered in pupils most preferred colours.

Cognitive impairment is common in elderly people, so it is considered an ageing disorder. However, cognitive decline, including dementia, can also occur in middle-aged people. Cognitive impairment is associated with multiple risk factors. We hypothesised that tooth loss might also be a potential risk factor among Mongolians, as oral health problems are one of the significant health issues in Mongolia, especially in middle-aged people. In this cross-sectional study, we used the baseline data from the Mon-Timeline cohort study, including people older than 40 years of age (n=279). The amount of tooth loss was assessed by a trained researcher. Mild cognitive impairment (MCI) was defined as those participants scoring a total of £ 24 points based on the Mini-Mental State Examination (MMSE). Unadjusted analysis showed that having more tooth loss (>10) increased the risk of MCI by an odds ratio of 3.03 (1.49-6.17), as compared with having less tooth loss (£10). Even after adjusting for covariates, the association remained significant, suggesting that tooth loss is associated with MCI risk, independent of age, education, and other socioeconomic factors. There was no significant interaction effect of age in the association between tooth loss and MMSE scores. In conclusion, tooth loss may play a role in developing cognitive decline, especially in the early onset of dementia. Further studies are needed to investigate whether early tooth loss at younger ages is associated with dementia, especially among middle-aged people.