Abstract
Purpose: Patient satisfaction with treatment is associated with adherence to therapy. This study aimed to investigate the treatment satisfaction level of patients with chronic obstructive pulmonary disease (COPD) and to explore the underlying factors associated with patient satisfaction. Methods: A cross-sectional study was conducted in ambulatory patients at the Second Xiangya Hospital, Changsha, Hunan, between August 1, 2020, and May 31, 2021. The Treatment Satisfaction Questionnaire for Medication version II (TSQM v. II) was used to assess the treatment satisfaction of patients. Multivariable regression analysis was used to determine the factors associated with treatment satisfaction. Results: 392 ambulatory patients with COPD first participated in the study, and 354 patients with are finally available. Median (IQR) score in effectiveness was 66.67(50.00, 66.67), in side effects was 100(100,100), in convenience was 66.67(66.67, 66.67), in global satisfaction was 66.67(50.00, 66.67).Compared with the unsatisfied group, the patients who were satisfied with the treatment had fewer acute exacerbations in the past year (0 vs 1,p<0.001), lower CAT scores(10 vs 13, p<0.001), lower CCQ scores(1.95 vs 2.24, p<0.001), lower GOLD group classification(p<0.001) and lower BODE index[3.00(1.00, 4.25) vs 3.00(2.00, 5.00), p=0.006]. Results indicate that different bronchodilator treatment didn't impact the satisfaction with treatment. The multivariable regression analysis showed that global satisfaction was associated positively with mMRC(β=2.814, p=0.027),while inversely with BMI(β=-0.542, p=0.014), FEV1%predicted(β=-0.135,P=0.024), CAT score(β=-0.342,p=0.033), BODE index(β=-2.057,p=0.023). Conclusion: The results of this study showed that the patients’ satisfaction with treatments is not high in COPD. Different bronchodilator treatment didn't impact the satisfaction with treatment. Keywords: chronic obstructive pulmonary disease, treatment satisfaction, TSQM v. II, bronchodilator