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    Clopidogrel Drug Study

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    Nicole Soo
    Clopidogrel is an antiplatelet drug that inhibits platelet aggregation by blocking the binding of ATP to platelet receptors. It is indicated to reduce atherosclerotic events such as heart attack, stroke, and vascular death in patients at risk. Clopidogrel should be discontinued 5-7 days before planned surgery and patients should be monitored for signs of bleeding or thrombotic thrombocytopenic purpura while on the drug.

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    Clopidogrel Drug Study

    Uploaded by

    Nicole Soo
    18K views1 page
    Clopidogrel is an antiplatelet drug that inhibits platelet aggregation by blocking the binding of ATP to platelet receptors. It is indicated to reduce atherosclerotic events such as heart attack, stroke, and vascular death in patients at risk. Clopidogrel should be discontinued 5-7 days before planned surgery and patients should be monitored for signs of bleeding or thrombotic thrombocytopenic purpura while on the drug.

    Original Description:

    A drug study on the drug Clopidogrel.

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    Clopidogrel is an antiplatelet drug that inhibits platelet aggregation by blocking the binding of ATP to platelet receptors. It is indicated to reduce atherosclerotic events such as heart attack, stroke, and vascular death in patients at risk. Clopidogrel should be discontinued 5-7 days before planned surgery and patients should be monitored for signs of bleeding or thrombotic thrombocytopenic purpura while on the drug.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    18K views1 page

    Clopidogrel Drug Study

    Uploaded by

    Nicole Soo
    Clopidogrel is an antiplatelet drug that inhibits platelet aggregation by blocking the binding of ATP to platelet receptors. It is indicated to reduce atherosclerotic events such as heart attack, stroke, and vascular death in patients at risk. Clopidogrel should be discontinued 5-7 days before planned surgery and patients should be monitored for signs of bleeding or thrombotic thrombocytopenic purpura while on the drug.

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    Name of Drug

    Clopidogrel 75 mg 1 tab PO OD

    General Action Antiplatelet agents; Platelet aggregation inhibitors

    Specific Action
    Inhibits platelet aggregation by irreversibly inhibiting the binding of ATP to platelet receptors. Therapeutic Effects: Decreased occurrence of atherosclerotic events in patients at risk.

    Indications
    Reduction of atherosclerotic events (MI, stroke, vascular death) in patients at risk for such events including recent MI, acute coronary syndrome (unstable angina/non-Q-wave MI), stroke, or peripheral vascular disease.

    Contraindications
    Contraindicated in: Hypersensitivity Pathologic bleeding (peptic ulcer, intracranial hemorrhage) Lactation. Use Cautiously in: Patients at risk for bleeding (trauma, surgery, or other pathologic conditions) History of GI bleeding/ulcer disease Severe hepatic impairment

    Adverse Reaction
    CNS: Depression, Dizziness, Fatigue, Headache. EENT: Epistaxis. Resp: Cough, Dyspnea. CV: Chest Pain, Edema, Hypertension. GI: GI Bleeding, Abdominal Pain, Diarrhea, Dyspepsia, Gastritis. Derm: Pruritus, Purpura, Rash. Hemat: Bleeding, Neutropenia, Thrombotic Thrombocytopenic Purpura. Metab: Hypercholesterolemia. MS: Arthralgia, Back Pain. Misc: Fever, Hypersensitivity Reactions.

    Nursing Responsibilities Assessment


    Assess patient for symptoms of stroke, peripheral vascular disease, or MI periodically during therapy. Monitor patient for signs of thrombotic thrombocytic purpura (thrombocytopenia, microangiopathic hemolytic anemia, neurologic findings, renal dysfunction, fever). May rarely occur, even after short exposure (<2 wk). Requires prompt treatment.

    Implementation
    Discontinue clopidogrel 5-7 days before planned surgical procedures. PO: Administer once daily without regard to food.

    Patient/Family Teaching
    Instruct patient to take medication exactly as directed. Take missed doses as soon as possible unless almost time for next dose; do not double doses. Advise patient to notify health care professional promptly if fever, chills, sore throat, or unusual bleeding or bruising occurs. Advise patient to notify health care professional of medication regimen prior to treatment or surgery.

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