NAEPP EPR-3 Classifi Cation of Asthma Severity & Control in Children 0-4 Years of Age
NAEPP EPR-3 Classifi Cation of Asthma Severity & Control in Children 0-4 Years of Age
NAEPP EPR-3 Classifi Cation of Asthma Severity & Control in Children 0-4 Years of Age
Impairment
Components of Severity
Persistent
Intermittent
Symptoms
Daily
1-2x/month
3-4x/month
> 1x/week
2 days/week
Daily
Several times/day
None
Minor limitation
Some limitation
Extremely limited
0-1/year
Risk
Severe
Moderate
2 days/week
Nighttime Awakenings
SABA Use (other than for EIB)
Mild
Consider severity and interval since last exacerbation. Frequency and severity may fluctuate over time.
Exacerbations of any severity may occur in patients in any severity category.
Step 1
Step 2
Step 3
and
Consider OSC
Step 3
and
Consider OSC
In 2-6 weeks, depending on severity, evaluate level of asthma control that is achieved. If no clear benefit is
observed in 4-6 weeks, consider adjusting therapy or alternative diagnoses.
Classifying Severity After Asthma Becomes Well-Controlled by Lowest Level of Treatment Required to Maintain Control
Persistent
Intermittent
Step 1
Mild
Moderate
Step 2
Severe
Step 3 or 4
Step 5 or 6
KEY: SABA-short-acting beta2-agonist; ICS-inhaled corticosteroids; OSC-oral systemic corticosteroids; EIB-exercise induced bronchospasm
NOTES:
Level of severity is determined by both impairment and risk. Assess impairment domain by patients/caregivers recall of previous 2-4 weeks. Symptom assessment for longer periods should
reflect a global assessment such as inquiring whether the patients asthma is better or worse since the last visit. Assign severity to the most severe category in which any feature occurs.
At present, there are inadequate data to correspond frequencies of exacerbations with different levels of asthma severity. For treatment purposes, patients who had 2
exacerbations requiring oral systemic corticosteroids in the past 6 months, or 4 wheezing episodes in the past year, and who have risk factors for persistent asthma may be
considered the same as patients who have persistent asthma, even in the absence of impairment levels consistent with persistent asthma.
Impairment
Components of Control
Symptoms
Nighttime Awakenings
Interference with Normal Activity
SABA Use (other than for EIB)
Risk
Classification of Control
Well Controlled
Not Well-Controlled
2 days/week
> 2 days/week
1x/month
> 1x/month
> 1x week
None
Some limitation
Extremely limited
2 days/week
> 2 days/week
Several times/day
0-1 year
2-3 year
> 3/year
KEY: SABA-short-acting beta2-agonist; ICS-inhaled corticosteroids; OSC-oral systemic corticosteroids; EIB-exercise induced bronchospasm
NOTES:
The level of control is based on the most severe risk category. Assess impairment domain by caregivers recall of previous 2-4 weeks. Symptom assessment for longer periods
should reflect a global assessment such as inquiring whether the patients asthma is better or worse since the last visit.
At present, there are inadequate data to correspond frequencies of exacerbations with different levels of asthma severity. In general, more frequent and intense exacerbations
(e.g., requiring urgent, unscheduled care, hospitalization, or ICU admission) indicate greater underlying disease severity. For treatment purposes, patients who had 2
exacerbations requiring oral systemic corticosteroids in the past year may be considered the same as patients who have persistent asthma, even in the absence of impairment
levels consistent with persistent asthma.
Before step up in therapy:
Review adherence to medication, inhaler technique, environmental control, and comorbid conditions.
If alternative treatment option was used in a step, discontinue it and use preferred treatment for that step.
Produced by the California Asthma Public Health Initiative (CAPHI). Based on NAEPP EPR-3 recommendations for classification of asthma severity and control for children 0-4 years of age.
This table was designed to assist the clinician and is not intended to replace the clinicians judgment or establish a protocol for all patients with a particular condition.
Revised 02/16/2010