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    BP Liquid Paraffin Emulsion

    Uploaded by

    NiiTa20
    This document provides the formula and preparation instructions for a liquid paraffin emulsion. The emulsion contains liquid paraffin, vanillin, chloroform, benzoic acid solution, methylcellulose, and saccharin sodium. To prepare it, water is boiled and methylcellulose is added to hydrate. Additional water, chloroform-benzoic acid mixture, and vanillin are added while stirring. Saccharin sodium is dissolved in water and added, and the mixture is diluted to 500mL with water. Liquid paraffin is added while stirring constantly and the emulsion is homogenized. The finished emulsion must contain 44.0-49.0% w/w liquid paraffin

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd

    BP Liquid Paraffin Emulsion

    Uploaded by

    NiiTa20
    319 views2 pages
    This document provides the formula and preparation instructions for a liquid paraffin emulsion. The emulsion contains liquid paraffin, vanillin, chloroform, benzoic acid solution, methylcellulose, and saccharin sodium. To prepare it, water is boiled and methylcellulose is added to hydrate. Additional water, chloroform-benzoic acid mixture, and vanillin are added while stirring. Saccharin sodium is dissolved in water and added, and the mixture is diluted to 500mL with water. Liquid paraffin is added while stirring constantly and the emulsion is homogenized. The finished emulsion must contain 44.0-49.0% w/w liquid paraffin

    Original Description:

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    Original Title

    Paraffin

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    This document provides the formula and preparation instructions for a liquid paraffin emulsion. The emulsion contains liquid paraffin, vanillin, chloroform, benzoic acid solution, methylcellulose, and saccharin sodium. To prepare it, water is boiled and methylcellulose is added to hydrate. Additional water, chloroform-benzoic acid mixture, and vanillin are added while stirring. Saccharin sodium is dissolved in water and added, and the mixture is diluted to 500mL with water. Liquid paraffin is added while stirring constantly and the emulsion is homogenized. The finished emulsion must contain 44.0-49.0% w/w liquid paraffin

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    319 views2 pages

    BP Liquid Paraffin Emulsion

    Uploaded by

    NiiTa20
    This document provides the formula and preparation instructions for a liquid paraffin emulsion. The emulsion contains liquid paraffin, vanillin, chloroform, benzoic acid solution, methylcellulose, and saccharin sodium. To prepare it, water is boiled and methylcellulose is added to hydrate. Additional water, chloroform-benzoic acid mixture, and vanillin are added while stirring. Saccharin sodium is dissolved in water and added, and the mixture is diluted to 500mL with water. Liquid paraffin is added while stirring constantly and the emulsion is homogenized. The finished emulsion must contain 44.0-49.0% w/w liquid paraffin

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
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    BP

    Liquid Paraffin Emulsion


    DEFINITION

    Liquid Paraffin
    500 mL

    Vanillin
    500 mg

    Chloroform
    2.5 mL

    Benzoic Acid Solution


    20 mL

    Methylcellulose 20
    20 g

    Saccharin Sodium
    50 mg

    Water
    A sufficient quantity

    Extemporaneous preparation

    The following directions apply.


    Heat about 120 mL of Water until it boils and add the Methylcellulose; when thoroughly hydrated
    add sufficient Water in the form of ice to produce 350 mL and stir until homogeneous. Mix the
    Chloroform and the Benzoic Acid Solution, dissolve the Vanillin in the mixture and add to the
    methylcellulose dispersion while stirring vigorously for 5 minutes. Add the Saccharin Sodium
    dissolved in Water and dilute to 500 mL with Water. Add the Liquid Paraffin, stirring constantly, and
    pass through a homogeniser.
    The oral emulsion complies with the requirements stated under Oral Liquids and with the following
    requirements.
    Content of liquid paraffin
    44.0 to 49.0% w/w.
    ASSAY
    To 5 g add 10 mL of water, extract with two 40 mL quantities of a mixture of 2 volumes of ethanol
    (96%), 3 volumes of petroleum spirit (boiling range, 40 to 60) and 3 volumes of ether and then
    with 30 mL of a mixture of equal volumes of petroleum spirit (boiling range, 40 to 60) and ether .
    Wash the combined extracts with 15 mL of 0.5M sodium hydroxide and then with 15 mL of water,
    evaporate the solvent, add 5 mL of acetone and evaporate again. Repeat the addition and
    evaporation of acetone until the residue is free from water, dry at 105 for 15 minutes and weigh.

    BNF
    Liquid paraffin Laxative (faecal softener)
    LIQUID PARAFFINU
    Indications constipation
    Cautions avoid prolonged use; contra-indicated in
    children under 3 years
    Side-effects anal seepage of paraffin and consequent
    anal irritation after prolonged use, granulomatous
    reactions caused by absorption of small quantities of
    liquid paraffin (especially from the emulsion), lipoid
    pneumonia, and interference with the absorption of
    fat-soluble vitamins

    Dose

    . See under preparation

    Liquid Paraffin Oral Emulsion, BPU


    Oral emulsion, liquid paraffin 5 mL, vanillin 5 mg,
    chloroform 0.025 mL, benzoic acid solution 0.2 mL,
    methylcellulose-20 200 mg, saccharin sodium
    500 micrograms, water to 10mL
    Dose ADULT over 18 years, 1030mL at night when
    required
    Counselling Should not be taken immediately before going
    to bed

    1.6.4

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