CV: Mr.

Cherdsak Maneeruttanarungroj

PERSONAL INFORMATION Name: Surname: Date of birth: Nationality: Address: Cherdsak Maneeruttanarungroj December 11, 1981 Thai 269 Phetkasem 92/2 Bangkaenure Bangkae BKK 10160, Thailand/ kasdrehc@hotmail.com

EDUCATIONAL BACKGROUND (Academic year) 2008 present 2003 2004 1999 2002 Ph.D. Biochemistry, Chulalongkorn University, Thailand (GPA 0.00) M.Sc. Biochemistry, Chulalongkorn University, Thailand (GPA 3.88) B.Sc. Biochemistry, Chulalongkorn University, Thailand (GPA 3.11)

RESEARCH EXPERIENCES I have started my PhD since 2008 in Cyanobacterial Biotechnology Laboratory, Biochemistry Department, Faculty of Science, Chulalongkorn University, Thailand. I have focused on the finding of new energy source for our world, and the green energy source like the hydrogen production by biophotolysis process interests me. For my work, I have screened several hydrogen-producing green microalgae and optimized the production condition for use as an alternative energy source. Genes involved in hydrogen metabolism in green algae were investigated and were monitored under nutrient deprivation to understand their function in vivo. In the past, I worked as research assistant at the Shrimp Molecular Biology and Genetics Laboratory (SMBGL) Bangkok Thailand, the same place where I performed my Master thesis work. My work is focused on an antimicrobial peptide gene isolated from the hemocyte cDNA library of the black tiger shrimp (P. monodon). Alternatively, I have additionally developed 30 type I microsatellite markers which were extended from my thesis area. I have done these works since June 2005. After relocated to a new job in January 2007, I have joined the Protein-Ligand Engineering and Molecular Biology Laboratory, National Center for Genetics Engineering and Biotechnology (BIOTEC), Thailand. At BIOTEC, my research was mainly focused on drug

screening for inhibiting malarial key enzyme (DHFR-TS) in Plasmodium falciparum via X-ray crystallography technique. In addition, I also earned experiences in data collection from National Synchrotron Radiation Research Center, Taiwan in 2008. During my Master thesis research, I worked on type I microsatellite markers to extend the genome mapping of the black tiger shrimp (Penaeus monodon). The work is intended to provide the additional markers to the previous P. monodon genetic linkage map of AIMS (The Australian Institute of Marine Science). I had developed 50 type I microsatellite markers in my study and found that 36 markers could be placed on the previous genetic linkage map.

POSITIONS May 2005 Dec 2006 Research assistance at Shrimp Molecular Biology and Genomics Laboratory, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand Jan 2007 May 2008 Research assistance at Protein-Ligand Engineering and Molecular Biology Laboratory, National Center for Genetics Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Ministry of Science and Technology, Thailand

SCHOLARSHIPS June 2009 May 2010 Academic scholarships from the 90th Anniversary of Chulalongkorn University Fund (Ratchadaphiseksomphote Endowment Fund), Bangkok, Thailand June 2008 May 2011 Academic scholarship from Thailand Research Fund through the Royal Golden Jubilee Ph.D. program, Bangkok, Thailand June 2004 May 2005 Local Graduate Scholarship (LGS). This scholarship was funded by National Center for Genetics Engineering and Biotechnology (BIOTEC) for local master degree student.

AWARDS 20 April 2012 Best presentation award from The Science Forum 2012 (Applies Science and Technology session). Mahamakut Building, Faculty of Science, Chulalongkorn University, Thailand: April 19 20, 2012. 03 April 2011 Outstanding presentation award from RGJ-Ph.D. Congress XII, Jomtein Palm Beach Resort Pattaya, Chonburi, Thailand: April 1 -3, 2011. 17 June 2010 Recognized as best graduate student, Chulalongkorn University, Thailand 21 August 2005 The excellent graduate student award, the Prof. Dr. Tab Nilanidhi Foundation (the award was presented to the student who received the highest GPA above 3.70 in each department). July 2005 Outstanding Thesis Award, Department of Biochemistry, Faculty of Science, Chulalongkorn University

ACADEMIC EXPERIENCES 1. Science Forum 2012, Faculty of Science, Chulalongkorn University, Thailand: April 19 20, 2012. High Rates of Hydrogen Production by a Novel Green Alga Tetraspora sp. CU2551 (Oral presentation). 2. RGJPh.D. Congress XII, Jomtein Palm Beach Resort Pattaya, Chonburi, Thailand: April 1 3, 2011. High Rates of Hydrogen Production by a Novel Green Alga Tetraspora sp. CU2551 (Oral presentation). 3. CAP meeting, Department of Photochemistry and Molecular Science, Uppsala University, Sweden: October 05, 2010. Identification and characterization of a novel hydrogenproducing green alga Tetraspora sp. CU2551 isolated from natural pond in Thailand (Oral presentation). 4. The 9th International Hydrogenase Conference, Uppsala, Sweden: June 27 July 2, 2010. Identification and characterization of a hydrogen-producing green alga Tetraspora sp. TURW 20.6 isolated from natural pond in Thailand (Poster presentation).

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The 14th Biological Sciences Graduate Congress. Faculty of Science, Chulalongkorn University, Bangkok, Thailand. December 10 12, 2009. Screening for photosynthetic hydrogen-producing bacteria and optimization for the hydrogen production (Poster presentation). The 13th Biological Sciences Graduate Congress. Faculty of Science, National University of Singapore, Singapore: December 15 16, 2008. Screening of hydrogen producing cyanobacteria from natural ponds in Thailand (Poster presentation). The 16th Annual Meeting of the Thai Society for Biotechnology on Innovative Biotechnology: The Opportunity for Kitchen of the World. 12 15 December 2004, Phitsanulok, Thailand (Poster presentation).

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PUBLICATIONS 1. Maneeruttanarungroj, C., Lindblad, P. and Incharoensakdi, A. (2012) Sulfate permease (SulP) and hydrogenase (HydA) in the green alga Tetraspora sp. CU2551: Dependence of gene expression on sulfur status in the medium. Int J Hydrogen Energ (accepted). (Impact 2010 = 4.053) 2. Maneeruttanarungroj, C., Lindblad, P. and Incharoensakdi, A. (2010) A newly isolated green alga, Tetraspora sp. CU2551, from Thailand with efficient hydrogen production. Int J Hydrogen Energ 35:13193-13199. (Impact 2010 = 4.053) 3. Nzila, A., Rottmann, M., Chitnumsub, P., Kiara, S. M., Kamchonwongpaisan, S., Maneeruttanarungroj, C., Taweechai, S., Yeung, B. K., Goh, A., Lakshminarayana, S. B., Zou, B., Wong, J., Ma, N. L., Weaver, M., Keller, T. H., Dartois, V., Wittlin, S., Brun, R., Yuthavong, Y. and Diagana, T. T. (2010) Preclinical evaluation of the antifolate QN254, 5chloro- N060-(2,5-dimethoxy-benzyl)-quinazoline-2,4,6-triamine, as an antimalarial drug candidate. Antimicrob Agents Chemother 54, 26032610. (Impact 2010 = 4.672) 4. Dasgupta, T., Chitnumsub, P., Kamchonwongpaisan, S., Maneeruttanarungroj, C., Nichols, SE., Lyons, TM., Tirado-Rives, J., Jorgensen, WL., Yuthavong, Y. and Anderson, K.S. (2009) Exploiting structural analysis, in silico screening, and serendipity to identify novel inhibitors of drug-resistant Falciparum malaria. ACS Chem Biol 4:2940. (Impact 2010 = 5.698)

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Supungul, P., Tang, S., Maneeruttanarungroj, C., Rimphanitchayakit, V., Hirono, I., Aoki, T. and Tassanakajon A. (2008) Cloning, expression and antimicrobial activity of crustinPm1, a major isoform of crustin, from the black tiger shrimp Penaeus monodon. Dev Comp Immunol 32, 6170. (Impact 2010 = 3.293)

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Maneeruttanarungroj, C., Pongsomboon, S., Wuthisuthimethavee, S., Klinbunga, S., Wilson, K.J., Swan, J., Li, Y., Whan, V., Chu, K.H., Li, C.P., Tong, J., Glenn, K., Rothschild, M., Jerry, D. and Tassanakajon, A. (2006) Development of polymorphic expressed sequence tag-derived microsatellites for the extension of the genetic linkage map of the black tiger shrimp (Penaeus monodon). Anim Genet 37, 363368. (Impact 2010 = 2.203)

TRAINING & ACTIVITIES 2010 Organizing committee of Cyanobacteria and algae biotechnology symposium. Department of Biochemistry, Faculty of Science, Chulalongkorn University, Thailand 2009 Organizing committee of the 14th Biological Sciences Graduate Congress. Faculty of Science, Chulalongkorn University, Bangkok, Thailand 2009 The president of Biochem Lover Club, Department of Biochemistry, Chulalongkorn University, Thailand 2008 X-ray diffraction data collection at National Synchrotron Radiation Research Center (NSRRC), Hsinchu, Taiwan (April 04-06, 2008) 2007 Training course on the School on Use of Synchrotron Radiation (April 23 May 4, 2007) at the National Synchrotron Research Center (NSRC), Nakhon Ratchasima, Thailand 2004 Registrar of the 17th FAOBMB Symposium/ 2nd IUBMB Special Meeting/ 7th A-IMBN Conference 2003 2002 2001 Equipment supplier staff of Graduated Committee of Chulalongkorn University Student trainee at Institute of Nutrition, Mahidol University (March - May) Deputy President (academic affairs) of Science Study Club of Chulalongkorn University

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Editor of science magazine (SCIMAX) of Science Study Club of Chulalongkorn University, Faculty of Science, Chulalongkorn University Staff of Young Leader Scientist Camp 6th - 9th of Science Study Club of Chulalongkorn University (in the position of Academic affairs, Assessment affairs, and Ceremony affairs)

1999 - 2002

REFEREES Professor Aran Incharoensakdi, Ph.D. Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand E-Mail: aran.i@chula.ac.th

Professor Peter Lindblad, Ph.D. Photochemistry and Molecular Science, Department of Chemistry ngstrm Laboratory, Uppsala University, Box 523, SE-75120, Uppsala, Sweden E-Mail: peter.lindblad@fotomol.uu.se

English proficiency: CU-TEP