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    Hiv Management of Pregnant Women Prophylactic Treatment

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    Vica Novalendya
    This document provides guidelines for HIV management and antiretroviral therapy (ART) for pregnant women living with HIV. It recommends: 1. Providing prophylactic cotrimoxazole treatment to prevent opportunistic infections and support ART. 2. Initiating ART during pregnancy depending on CD4 count and clinical stage, including combination regimens of ARV drugs from different classes. 3. Continuing the mother's existing ART regimen during pregnancy and labor if she was already receiving treatment prior.

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    Hiv Management of Pregnant Women Prophylactic Treatment

    Uploaded by

    Vica Novalendya
    16 views3 pages
    This document provides guidelines for HIV management and antiretroviral therapy (ART) for pregnant women living with HIV. It recommends: 1. Providing prophylactic cotrimoxazole treatment to prevent opportunistic infections and support ART. 2. Initiating ART during pregnancy depending on CD4 count and clinical stage, including combination regimens of ARV drugs from different classes. 3. Continuing the mother's existing ART regimen during pregnancy and labor if she was already receiving treatment prior.

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    This document provides guidelines for HIV management and antiretroviral therapy (ART) for pregnant women living with HIV. It recommends: 1. Providing prophylactic cotrimoxazole treatment to prevent opportunistic infections and support ART. 2. Initiating ART during pregnancy depending on CD4 count and clinical stage, including combination regimens of ARV drugs from different classes. 3. Continuing the mother's existing ART regimen during pregnancy and labor if she was already receiving treatment prior.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    16 views3 pages

    Hiv Management of Pregnant Women Prophylactic Treatment

    Uploaded by

    Vica Novalendya
    This document provides guidelines for HIV management and antiretroviral therapy (ART) for pregnant women living with HIV. It recommends: 1. Providing prophylactic cotrimoxazole treatment to prevent opportunistic infections and support ART. 2. Initiating ART during pregnancy depending on CD4 count and clinical stage, including combination regimens of ARV drugs from different classes. 3. Continuing the mother's existing ART regimen during pregnancy and labor if she was already receiving treatment prior.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 3

    HIV MANAGEMENT OF PREGNANT WOMEN

    prophylactic treatment
    Indication when termination dose
    If not available CD4 cell count
    examination, all patients were
    given co-trimoxazole
    immediately after being
    declared HIV positive
    2 years after the use of co-
    trimoxazole if getting ARVs.




    960 mg / day
    single dose When the examination is
    available and affordable CD4
    cell count, given co-
    trimoxazole
    in patients with CD4 counts
    <200 cells/mm3
    When CD4 cells rose> 200
    cells/mm3 at examination 6
    months intervals two times in
    a row if you get ARVs
    All infants born to HIV-
    positive pregnant women
    aged 6 weeks
    Discontinued at the age of 18
    months with a negative HIV
    test results if tested HIV
    positive at the age of 18
    months suspended if
    antiretroviral therapy

    Trimetropim 8-10 mg / kg
    body weight single dose
    Prophylactic treatment with cotrimoxazole: To prevent opportunistic infections and to train
    patients using antiretroviral drugs.
    ARV therapy for pregnant women
    NO. clinical situation Treatment recommendations
    (Alloys for Mother)
    1. People living with HIV with antiretroviral therapy
    indications and the possibility of pregnancy or are
    pregnant

    AZT plus 3TC + NVP or
    TDF plus 3TC (or FTC) + NVP
    Avoid EFV in the first trimester
    AZT + 3TC + EVF * or
    TDF plus 3TC (or FTC) + EVF *

    2. PLWHA are using therapy ARV and then pregnant

    Continue alloy (replace with
    NVP or PI class if it is using
    EFV in trimester I)
    Continue to ARVs same
    during and after labor

    3. Pregnant PLWHA with CD4 counts> 350/mm3 or in
    clinical stage 1.
    ARV began at week 14
    gestation

    4. Pregnant PLWHA with CD4 counts <350/mm3 or in
    clinical stage 2, 3 or 4
    Alloy in accordance with
    item 1 Immediate Start ARV
    Therapy
    Description:
    *: The drug should not be administered in the first trimester of pregnancy PLWHA

    ARV drugs
    Class of drug NRTI (nucleoside Reverse Transcriptase Inhibitor): Zidovudine,
    didanosin, emtristabin, abakavir, zalsitabin, stavudin, lamivudine.
    Class of NNRTIs (non-nucleoside Reverse Transcriptase Inhibitor): nevirapin,
    evapiren, and delavirdin.
    Group Protease Inhibitor: Indinavir, nelfinavir, sakuinavir, ritonavir, nelfinavir,
    amprenavir, lopinavir, atazanavir.
    NtRTI groups: tenofovir Disoproksil
    Group Viral Entry Inhibitors: Enfurtid.
    ARV DRUGS IN SCENARIO

    Name drug

    mechanisms of
    drug
    dose Side effect
    Stavudine This drug works
    on HIV RT by
    stopping the
    formation of
    the viral DNA
    chain.
    30 mg; given every 12
    hours
    Peripheral neuropathy,
    lipodystrophy and lactic
    acidosis is side effects
    often arise. The third
    examination the above
    symptoms should be
    carried out
    continuously.
    Another ES Pancreatitis
    Zidovudine Inhibit viral
    enzymes RT,
    after the AZT
    group
    250-300 mg every 12
    hours. Dose of 250 mg
    can be administered
    without
    There needs to be
    monitoring the side
    effects of bone marrow
    suppression (anemia
    phosphorylated
    zidovudine. AZT
    group 5 'mono
    phosphate will
    join the 3' end
    of the chain.
    Viral DNA and
    inhibit the RT
    reaction
    mengurangefektifivatas
    AZT with the possibility
    of side effects is lower.
    Dose of 250 mg is
    temporarily
    unavailable in
    Indonesia
    macrocytic or
    netropeni)
    Another ES: lactic
    acidosis with steatosis
    hepatitis (rare);
    gastrointestinal
    intolerance; headache;
    difficulty sleeping;
    myopathy;
    pigmentation of the
    skin and nails.
    Lamivudine This drug works
    on HIV RT and
    HBV RT by
    stopping the
    formation of
    the viral DNA
    chain.
    150 mg; given every 12
    hours
    or 300 mg every 24
    hours
    low toxicity
    Side effects of lactic
    acidosis with steatosis
    hepatitis
    (rarely)
    Nevirapine Work on the
    site allosteric
    binding site of
    HIV-1 non
    subtract RT.
    200 mg every 24 hours
    selama14 days, then
    200 mg every 12 hours
    Side effects are dose
    dependent nevirapine,
    so for the first 2 weeks
    of dose escalation
    200mg/dosis
    performed single and
    200 mg / 12 hours on
    day 15 and onwards.
    Other side effects of
    nevirapine to note is
    hepatotoxic.

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