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    Homework 1

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    Hayley Patton
    A polymer would be the best material for an arterial graft for several reasons: 1) Polymers are the only material that can be made flexible enough to withstand varying blood pressures. 2) Polymers can be designed with characteristics like flexibility and the ability to change shape under pressure, which is essential for a blood vessel graft. 3) While metals and ceramics are strong, they cannot match polymers' flexibility and ability to change shape, which is necessary for an arterial graft application.

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    Homework 1

    Uploaded by

    Hayley Patton
    352 views2 pages
    A polymer would be the best material for an arterial graft for several reasons: 1) Polymers are the only material that can be made flexible enough to withstand varying blood pressures. 2) Polymers can be designed with characteristics like flexibility and the ability to change shape under pressure, which is essential for a blood vessel graft. 3) While metals and ceramics are strong, they cannot match polymers' flexibility and ability to change shape, which is necessary for an arterial graft application.

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    Bio-materials homework

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    A polymer would be the best material for an arterial graft for several reasons: 1) Polymers are the only material that can be made flexible enough to withstand varying blood pressures. 2) Polymers can be designed with characteristics like flexibility and the ability to change shape under pressure, which is essential for a blood vessel graft. 3) While metals and ceramics are strong, they cannot match polymers' flexibility and ability to change shape, which is necessary for an arterial graft application.

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    © All Rights Reserved
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    Download as docx, pdf, or txt
    352 views2 pages

    Homework 1

    Uploaded by

    Hayley Patton
    A polymer would be the best material for an arterial graft for several reasons: 1) Polymers are the only material that can be made flexible enough to withstand varying blood pressures. 2) Polymers can be designed with characteristics like flexibility and the ability to change shape under pressure, which is essential for a blood vessel graft. 3) While metals and ceramics are strong, they cannot match polymers' flexibility and ability to change shape, which is necessary for an arterial graft application.

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    Hayley Patton

    January 27, 2016

    Biomaterials BMED 4200 Spring 2016

    Homework #1
    1. One common biomaterial application is the construction of an arterial graft, a device that replaces a
    section of an artery. An artery is a flexible blood vessel that withstands varying pressures and regulates
    the flow of blood. Arteries also provide a smooth interior surface to inhibit blood clotting within the
    vessel.
    a. You need to design an arterial graft. List some advantages and disadvantages of each of the three
    major types of biomaterials. Which would you choose for this application?
    Ceramics:
    Pros:
    -Strong, rigid
    Cons:
    -might promote un-wanted clotting, not flexible, pieces could break off, cant change shape
    Metal:
    Pros:
    -Strong, smooth (so no unwanted clotting),
    Cons:
    -not flexible at all, could corrode (select the right type), cant change shape
    Polymers:
    Pros:
    -Strong, flexible, can do different types to help with unwanted clotting, can change shape with pressure
    Cons:
    -depends on the type you use
    For this application, I would use a polymer. I would use this type of material because it is the only material that
    can be made flexible. Also you can make a polymer that can with stand different types of pressures, which is
    essential for a graft.
    b. What specific material characteristics need to be considered for the arterial graft application?
    You need to make sure the material you choose will no corrode with blood. You also need to make sure the
    material can change shape when different pressures of fluid move through it, also keeping in mind that the
    material has to with stand these different types of pressure.
    c. Would you use a natural or synthetic material for this application? What are the advantages and
    disadvantages of each?
    I would use a synthetic material. The advantages of this is that you can design the material to the specifications
    that you want for the blood vessel. The disadvantages of using a synthetic material would be that the body
    could reject it. The advantages of using a natural material, is that the body wont have to adapt as much as it
    would have to with a synthetic material. A disadvantage of this type of material is that you would only have a

    limited amount, and the material may not be able to withstand the types of pressures that are present in blood
    vessels.
    2. Various biomaterials can be used for joint replacement applications, such as hip implants. A hip joint
    replacement must withstand large forces (standing on one leg results in a load 2.4 times body weight on
    the femoral head; jumping and running generate higher forces) normally transferred through the hip
    joint. It must also allow for proper rotation of the joint.
    a. Which of the three major types of biomaterials would you use for the femoral stem? Why?
    Of the three biomaterials, I would use metal as well as ceramics for the femoral stem. I would use this
    material, because it can with stand high amounts of force. Metal can also be made so move in many different
    ways. I would use ceramics to give the metal more texture to interact with the bone. I would also use ceramics
    in order to keep the strength of the implant.
    b. Would integration of the femoral stem with the surrounding tissue be an acceptable biological
    response? Why or why not?
    Integration of the femoral stem with the surrounding tissue would be an ideal biological response. This would
    be ideal because if the stem was not integrated with the surrounding tissue, the implant would not be as strong,
    and it also would not stay in the leg. The femoral stem would risk coming out of the bone, if it was not
    properly integrated.

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