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    Longifene ... Longifene-... Stimulone: Available Brands

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    Justin Raul Dela Cuadra
    Bucilizine is an oral antihistamine used for the prophylaxis of motion sickness, treatment of migraine, nausea and vomiting, and pruritic skin disorders. It should be taken with food within 30 minutes before meals. Special precautions should be taken when using bucilizine due to risks of drowsiness, blurred vision, and interactions with other CNS depressants. The drug is pregnancy category C and works as an antihistamine with antimuscarinic and sedative properties.

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    Longifene ... Longifene-... Stimulone: Available Brands

    Uploaded by

    Justin Raul Dela Cuadra
    106 views2 pages
    Bucilizine is an oral antihistamine used for the prophylaxis of motion sickness, treatment of migraine, nausea and vomiting, and pruritic skin disorders. It should be taken with food within 30 minutes before meals. Special precautions should be taken when using bucilizine due to risks of drowsiness, blurred vision, and interactions with other CNS depressants. The drug is pregnancy category C and works as an antihistamine with antimuscarinic and sedative properties.

    Original Description:

    Bucilizine drug study

    Original Title

    Bucilizine

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    Bucilizine is an oral antihistamine used for the prophylaxis of motion sickness, treatment of migraine, nausea and vomiting, and pruritic skin disorders. It should be taken with food within 30 minutes before meals. Special precautions should be taken when using bucilizine due to risks of drowsiness, blurred vision, and interactions with other CNS depressants. The drug is pregnancy category C and works as an antihistamine with antimuscarinic and sedative properties.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    106 views2 pages

    Longifene ... Longifene-... Stimulone: Available Brands

    Uploaded by

    Justin Raul Dela Cuadra
    Bucilizine is an oral antihistamine used for the prophylaxis of motion sickness, treatment of migraine, nausea and vomiting, and pruritic skin disorders. It should be taken with food within 30 minutes before meals. Special precautions should be taken when using bucilizine due to risks of drowsiness, blurred vision, and interactions with other CNS depressants. The drug is pregnancy category C and works as an antihistamine with antimuscarinic and sedative properties.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 2

    Bucilizine

    Available Brands
    LONGIFENE ...
    LONGIFENE-...
    STIMULONE

    Indication &
    Dosage

    Oral
    Prophylaxis of motion sickness
    Adult: As hydrochloride: 25 or 50 mg given 30 min before travelling,
    repeated after 4-6 hr, if necessary.
    Oral
    Migraine
    Adult: As hydrochloride: 12.5 mg taken as soon as symptoms arise.
    Child: 10-14 yr: 6.25 mg at the start of the symptoms. >14 yr: follow adult
    dose.
    Oral
    Nausea and vomiting
    Adult: As hydrochloride: 25 or 50 mg tid.
    Oral
    Pruritic skin disorders
    Adult: As hydrochloride: 25-50 mg daily.

    Administration

    Should be taken with food. Take w/in hr before meals.

    Contraindications

    Hypersensitivity; neonates.

    Special
    Precautions

    Driving or operating machinery; open-angle glaucoma; urinary retention;


    prostatic hyperplasia, pyloroduodenal obstruction, epilepsy; renal and
    hepatic impairment; pregnancy.

    Adverse Drug
    Reactions

    Drowsiness, dizziness, incoordination; blurred vision; urinary retention;


    vomiting; rash; dry mouth; headache, nausea, epigastric pain, wt gain and
    diarrhoea.

    Drug Interactions

    Potentially Fatal: Effect of alcohol, sedatives and other CNS depressants


    potentiated.

    Pregnancy
    Category (US

    FDA)

    Category C: Either studies in animals have revealed adverse effects on


    the foetus (teratogenic or embryocidal or other) and there are no controlled
    studies in women or studies in women and animals are not available.
    Drugs should be given only if the potential benefit justifies the potential risk
    to the foetus.

    Mechanism of
    Action

    Buclizine is a piperazine antihistamine with antimuscarinic and moderate


    sedative properties. It is used mainly for its antiemetic action and in the
    treatment of migraine in combination with analgesics.

    CIMS Class

    Antihistamines & Antiallergics

    B-Complex

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