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    Portable Medical Diagnosis Instrument: Instrumentation

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    Glenn Miller
    NASA has developed a portable medical diagnosis instrument that integrates four cutting-edge sensor technologies into a compact, hand-held device. The device can non-invasively analyze samples like saliva, breath, and blood to measure various analytes and provide health assessments. It uses a carbon nanotube array to detect molecules in breath, a condenser to isolate nonvolatile compounds, a miniaturized differential mobility spectrometer-like device to detect volatile and nonvolatile molecules, and a centrifugal microfluidics disk to detect analytes and perform blood cell counts from liquid samples. This innovative technology could have applications in space missions, healthcare, homeland security, and more.

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    Portable Medical Diagnosis Instrument: Instrumentation

    Uploaded by

    Glenn Miller
    90 views2 pages
    NASA has developed a portable medical diagnosis instrument that integrates four cutting-edge sensor technologies into a compact, hand-held device. The device can non-invasively analyze samples like saliva, breath, and blood to measure various analytes and provide health assessments. It uses a carbon nanotube array to detect molecules in breath, a condenser to isolate nonvolatile compounds, a miniaturized differential mobility spectrometer-like device to detect volatile and nonvolatile molecules, and a centrifugal microfluidics disk to detect analytes and perform blood cell counts from liquid samples. This innovative technology could have applications in space missions, healthcare, homeland security, and more.

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    Portable Medical Diagnosis Instrument - NASA

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    TOP2-246

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    NASA has developed a portable medical diagnosis instrument that integrates four cutting-edge sensor technologies into a compact, hand-held device. The device can non-invasively analyze samples like saliva, breath, and blood to measure various analytes and provide health assessments. It uses a carbon nanotube array to detect molecules in breath, a condenser to isolate nonvolatile compounds, a miniaturized differential mobility spectrometer-like device to detect volatile and nonvolatile molecules, and a centrifugal microfluidics disk to detect analytes and perform blood cell counts from liquid samples. This innovative technology could have applications in space missions, healthcare, homeland security, and more.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    90 views2 pages

    Portable Medical Diagnosis Instrument: Instrumentation

    Uploaded by

    Glenn Miller
    NASA has developed a portable medical diagnosis instrument that integrates four cutting-edge sensor technologies into a compact, hand-held device. The device can non-invasively analyze samples like saliva, breath, and blood to measure various analytes and provide health assessments. It uses a carbon nanotube array to detect molecules in breath, a condenser to isolate nonvolatile compounds, a miniaturized differential mobility spectrometer-like device to detect volatile and nonvolatile molecules, and a centrifugal microfluidics disk to detect analytes and perform blood cell counts from liquid samples. This innovative technology could have applications in space missions, healthcare, homeland security, and more.

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    Portable Medical Diagnosis Instrument

    National Aeronautics and


    Space Administration

    BENEFITS
    User-friendly, compact
    design, versatile, and hand-
    held device
    Graphical User Interface for
    data distillation,
    visualization, and overall
    system control to occur

    technology solution
    remotely
    Phone-sensor device
    Instrumentation possesses high sensitivity
    (parts-per-billion/parts per
    million), fast response time
    (seconds), high selectivity,
    Portable Medical Diagnosis both wireless and wired
    capabilities, and low power

    Instrument system
    DMS-type device provides
    Compact In-Flight Medical Diagnostic Technology for analyte separation based
    on differences in ion
    Deep-Space Missions mobility at high and low
    electric fields
    NASA has developed a novel technology strategy called "The NASA Centrifugal analyzer is a
    Analyzer" that would provide comprehensive in-flight medical low-power, portable, has
    high analytical sensitivity
    diagnostic capability in a compact, hand-held device for human deep- and easy to use device for
    space missions such as Mars. Key features of the technology include carrying out multiple
    immunoassays and cell-
    the ability to handle multiple sample types (breath, saliva, blood), and based analyses
    the ability to measure virtually any analyte, including future analytes
    Non-invasive and minimal
    as they emerge. The device provides both non-invasive and invasive specimens and
    does not require sample
    minimally invasive sampling capabilities, which will be required during
    preparation prior to loading
    long-duration exploration missions. Breath and saliva are fully non- sample into the device
    invasive and can provide critical health assessment information very Operates in real-time and
    rapidly. From small blood samples, information about generates multi-dimentional
    signals
    macromolecular analytes as well as blood cell counts can be
    Software can be tailored to
    obtained. The device consists of four cutting-edge technologies
    identify biomarkers of
    integrated into a single compact medical diagnostic tool with wireless interest without the
    (e.g., smart phone) capability. In addition to space applications, this requirement of hardware
    modification
    innovative technology will very likely have important spin-offs in
    Sensor can be "refreshed"
    medicine and public health on Earth. for continuous use
    NASA Technology Transfer Program
    Bringing NASA Technology Down to Earth

    THE TECHNOLOGY APPLICATIONS


    The technology utilizes four cutting-edge sensor technologies to enable minimally- or The technology has several potential
    non-invasive analysis of various biological samples, including saliva, breath, and blood. applications:
    The combination of technologies and sample pathways have unique advantages that
    collectively provides a powerful analytical capability. The four key technology Space missions
    components include the following: (1) the carbon nanotube (CNT) array designed for the Health care industry
    detection of volatile molecules in exhaled breath; (2) a breath condenser surface to
    Homeland security
    isolate nonvolatile breath compounds in exhaled breath; (3) the miniaturized differential
    mobility spectrometer (DMS) -like device for the detection of volatile and non-volatile Field-testing and clinical diagnostics
    molecules in condensed breath and saliva; and (4) the miniaturized circular disk (CD)- Military and disaster response
    based centrifugal microfluidics device that can detect analytes in any liquid sample as
    well as perform blood cell counts. As an integrated system, the device has two ports for Remote/harsh environments
    sample entry a mouthpiece for sampling of breath and a port for CD insertion. The breath
    analysis pathway consists of a CNT array followed by a condenser surface separating
    liquid and gas phase breath. The exhaled breath condensate is then analyzed via a DMS- PUBLICATIONS
    like device and the separated gas breath can be analyzed by both CNT sensor array again Patent No: 9,824,870
    and by DMS detectors.
    Tore Straume, David J. Loftus, Jing Li,
    Matthew A. Coleman, Cristina E. Davis,
    Kathleen A. McMonigal, Matthew Piccini, and
    Anup K. Singh (2013) Biomarker-Detection
    Technologies for Comprehensive Medical
    Diagnosis During Deep-Space Missions,
    Recent Patents on Space Technology 3, 13-
    23.

    Examples of Concept Devices

    National Aeronautics and Space Administration NASA's Technology Transfer Program


    pursues the widest possible applications
    Technology Partnerships Office of agency technology to benefit US
    Ames Research Center citizens. Through partnerships and
    licensing agreements with industry, the
    MS 202A-3 program ensures that NASA's investments
    Moffett Field, CA 94035 in pioneering research find secondary
    855-627-2249
    uses that benefit the economy, create
    ARC-TechTransfer@mail.nasa.gov
    jobs, and improve quality of life.
    http://technology.nasa.gov/
    ARC-17171-1
    www.nasa.gov TOP2-246

    NP-2015-05-1834-HQ

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