Module-1

S. No. Subject Topic (Details given in the syllabus)

1 Physical chemistry i) Composition and physical state of matter,
ii) Refractive Index,
iii) Solutions
2 Physical pharmacy Surface & Interfacial Phenomenon
Buffers
Solubility
3 Organic chemistry Hybridization,
Electrophiles & Nucleophiles
Alkanes ( Including cyclic compounds)
Alkenes ( Including cyclic compounds)
Alkynes (Only open chain compounds)
4 Pharmaceutical i) Dentifrices, Desensitizing agent, and Anticaries agent
Inorganic chemistry ii) Diagnostic agent
iii) Limit Test
5 Pharmaceutics Introduction to dosage form
6 Microbiology Microscopy and staining techniques, Sterilization &Disenfection

7 Pharmacology General pharmacology

i) Route of administration
ii) ADME
iii) Clinical trial, Type and phases of clinical trials, Placebo,
ethical and regulatory issues including good clinical
practice trials
8 Pharmacognosy i) Classification of crude drugs
ii) Factors influencing quality of crude drug
iii) Techniques in microscopy

9 P'ceutical analysis Acid-Base titration

Gravimetry
Oxygen flask Combustion method
10 Biotechnology Plant cell and tissue culture
11 Biochemistry Vitamins
12 Anatomy, Physiology i) Cell physiology
and Health education ii) Sense Organs
13 P'ceutical Engineering i) Flow of fluid
ii) Heat transfer
14 P'ceutical jurisprudence i) Historical background drug legislation in india, Code of
ethics for pharmacists.
ii) The pharmacy act 1948 (Inclusive of recent amendments)
 Module-2
S. No. Subject Topic(Details given in the syllabus)

1 Physical Chemistry Colligative Properties, Phase rule

2 Physical Pharmacy Dispersion Systems (Colloids, Emulsion & Suspensions)

3 Organic chemistry Stereochemistry, Aromatic & Aliphatic amines, Diazonium salts, Aromatic nitro
compounds

4 Inorganic chemistry GIT agents, Topical agents

5 Pharmacognosy Quantitative microscopy, Adulteration & Evaluation of crude drugs, Biogenetic

Pathways, Quality control &standardization of crude drugs

6 P'ceutical analysis Non-aqueous titration, Redox titration, Diazotozationtitration, Kjeldahl’s

Method, Karl-fischertitration

7 Pathophysiology Hypersensitivity

8 Clinical pharmacy i) Therapeutic drug monitoring , Adverse drug reaction(ADR) , Type of ADR,
and Therapeutics Mechanism of ADR, .Drug interaction, Monitoring and reporting of ADR and its
Significance .
ii) Drug interactions.

9 Microbiology Microbiology of Bacteria

10 Biochemistry Enzyme

11 APHE Skeletal System, Lymphatic System

12 P'ceutical Evaporation, Distillation

Engineering

13 P'ceutical i) Drug and cosmetic act 1940, rule 1945, Including new drug
jurisprudence application.
ii) Narcotic drug and psychotropic substance act , and rules there
under

14 Dispensing and Posology &Preparations of formulations involving allegation,

Hospital pharmacy alcohol dilution, isotonic solution.
 Module-3
S. No. Subject Topic(Details given in the syllabus)

1 Physical chemistry Thermodynamics

2 Physical pharmacy Micromeretics& Powder rheology& Complexation

3 Organic chemistry Aliphatic hydroxyl compounds& Ether

Alkyl & Aryl Halide, Carboxylic acid, All functional derivative of carboxylic
acid, Aromatic hydrocarbons, Phenolic compounds

4 Inorganic chemistry Antidotes, Radiopharmaceuticals, Respiratory Stimulants

5 Pharmacognosy Alkaloids

6 P'ceutical analysis Precipitation titration, Complexometric titration

7 Biochemistry Biological Oxidation & Reduction, Hereditary disease

8 Biotechnology Immunology, Fermentation technology, Biotechnology derived products

(Vaccines, Sera, Toxoids, rDNA products)

9 Microbiology Fungus

10 Pathophysiology Auto-immunity and disease of immunity

11 Pharmaceutics Semi-solid dosage forms, Suppositories, Powders

12 APHE GIT, Respiratory system, Blood, Reproductive system

Pharmacology & Drugs acting on GIT, Drugs acting on the Respiratory system, Coagulants,
Medicinal chemistry anticoagulants and plasma expander

13 P'ceutical Drying, Size reduction and size separation

Engineering

14 P'ceutical Inventory management

Management

15 P'ceutical i) Drugs and magic remedies (Objectionable advertisements) act 1954 .

jurisprudence ii) Medical and toilet preparations ( Excise duties) act 1955, rules 1976.
 Module-4
S. No. Subject Topic(Details given in the syllabus)

1 Physical chemistry Chemical & Ionic equilibria, Electrochemistry

2 Physical pharmacy Viscosity &rheology

3 Organic chemistry Aromaticity & Chemistry of aromatic compounds

4 Anatomy, Physiology i) Urinary System

and Health education ii) Endocrine system

5 Pharmacology & i) Drugs acting on urinary system (Diuretics)

Medicinal chemistry ii) Drugs acting on endocrine system (Steroidal drugs &
Hormones)
iii) Insulin & Oral Hypoglycemic drugs

6 Pharmaceutics i) Aerosols
ii) Parentral

7 P'ceutical analysis Electrochemical titration (Conductometry, Potentiometry,

Polarography, Amperometry)

8 Biochemistry Nucleic acids

9 Biotechnology Recombinant DNA technology

10 Microbiology Virus

11 P'ceutical i) Extraction
Engineering ii) Mixing

12 P'ceutical i) Medical termination of pregnancy act 1970 and rules 1975.

jurisprudence ii) Prevention of cruelty of animals act 1960.

13 Dispensing and Incompatibility: Prescription based on physical, chemical and

Hospital pharmacy therapeutic incompatibility . Tablet
Inhalation
 Module-5
S. No. Subject Topic(Details given in the syllabus)

1 Organic chemistry Polycyclic aromatic hydrocarbons (Napthalene, Antracene,

Phenanthrene), Bridged compounds (C8,C9,C11 bridged bicyclic
alkanes), Chemistry of Hexamine, Morphane, Biperidine, AMantidine,
Diazabicyclo[2,2,2]Octane

2 Pharmacology & i) Drugs acting on Peripheral (Somatic) Nervous system

Medicinal - Skeletal Muscle relaxants & Local Anesthetics
chemistry ii) Autacoids& Related drugs
- Histaminic & Antihistaminic drugs.
- Serotonergic drugs
- Prostaglandins & NSAID’s
- Drugs for Gout & Rheumatoid arthritis
3 Pharmaceutics Preformulations, Stability of formulated products,

4 Pharmacognosy Carbohydrates

5 P'ceutical analysis Chromatography, Nephelometry&Turbidimetry

6 Biochemistry Carbohydrates

7 Biotechnology PCR & Blotting Techniques

8 Microbiology Microbiological Assays

9 P'ceutical Crystallization, Filtration, Centrifugation

Engineering

10 P'ceutical Marketing research

Management

11 P'ceutical Drug price control order(DPCO)

jurisprudence

12 Dispensing and Procurement of information for the given drug information services.
Hospital pharmacy Preparation of hospital formulary
 Module-6
S.No. Subject Topic(Details given in the syllabus)

1. Organic chemistry a) Chemistry for Aldehyde & Ketones

b) Carbonyl chemistry-
i) Wolf- kishner reduction and huang-Minlong modification.
ii) Reduction of arylsulfonyl hydrazine/ Hydrazones to alkanes
iii) Bamford-Steven reaction
iv) DCC oxidation of alcohol
c) Protection &DE-protection of groups

2. Anatomy, Autonomic Nervous System (ANS)

Physiology and
Health education
3. Pharmacology& Drugs acting on Autonomic Nervous System (ANS)
Medicinal
Chemistry
4. Pharmacognosy i) Tannins
ii) Volatile oils & Resinous drugs

5. P’ analysis i) General Principles of spectroscopy

ii) UV-Visible spectroscopy

6. Biochemistry Amino acids & Proteins

7. P’ jurisprudence i) Factory act

ii) Consumer protection act

8. P’ Engineering i) Refrigeration and air conditioning

ii) Material of construction. (Packaging, Pilot Plant)
9. Pharmaceutics Tablets & Tablet Coating
 Module -7
S.No. Subject Topic(Details given in the syllabus)

1. Organic chemistry Carbonyl chemistry-

i) Michael addition / 1,4-addition/conjugate addition
ii) Mannich condensation / reaction
iii) Robinson annulations
iv) Stobbe condensation
v)Darzen’sglysidic ester synthesis
vi) Beckmann rearrangement
vii) Baeyer villager rearrangement
viii) Curtius, Wolff, and Lossen rearrangement
ix) Willgerodt rearrangement
x) Pinacolpinacolone rearrangement
xi) Methylene transfer reaction. Use of diazomethane and
Sulphurylides in the same
xii) Mono-and dialkylation in 1,3-dicarbonyl compounds
xiii) Formation and use of enol ethers, enol acetates and
enamines as protective group & in regiospecificalkylations

2. Pharmaceutics Capsules

3. P’ analysis Spectroflourimetry, Flame photometry, Atomic absorption

spectroscopy

4. Anatomy, Physiology Cardiovascular system

and Health education
5. Pharmacology & Drugs acting on Cardiovascular system
Medicinal chemistry

6. Biochemistry Lipids

7. Pharmacognosy Lipoidal drugs

8. P’ jurisprudence Industrial development and regulation act 1951.

9. Biotechnology Electrophoresis (Gel, Agarose-gel, SDS-page), Hybridoma

Technology, ELISA, RIA,
 Module -8
S.No. Subject Topic(Details given in the syllabus)

1. Organic chemistry Heterocyclic Chemistry

2. Anatomy, Physiology Central Nervous System

and Health education
3. Pharmacology & Drugs acting on Central Nervous System
Medicinal chemistry

4. Pharmaceutics i) NDDS, TDS

ii) Cosmetic technology
iii) Packaging technology
5. Pharmacognosy Glycosides

6. P’ analysis IR spectrometry

7. Biopharmaceutical and Bio – pharmaceutical statistics

p’ cokinetic
8. Biotechnology Gene Expression (DNA replication, Transcription,
Translation)
9. P’ Management GATT

10. P’ jurisprudence i) Introduction to Intellectual properties rights and Indian

patent act 1970.
ii) An introduction to standard institutions and regulatory
authorities such as – BIS, ASTM , ISO , TGA, USFDA, MFRA,
ICH, GMP, WHO.
 Module -9
S.N. Subject Topic (Details given in the syllabus)
1. Organic chemistry Pericyclic Chemistry

2. Pharmacology & Chemotherapy

Medicinal chemistry i) Anti-cancer agents
ii) Penicillin’s, Cephalosporin, and other beta lactam
antibiotic like – imipenam and aztreonam. Beta
lactam inhibitor’s such as clavulanic acid and
sulbactum.
iii) Choramphenicol.
iv) Tetracycline’s.
v) Aminoglycoside antibiotics.
vi) Macrolide antibiotic.
vii) Lincomycin.
viii) Polypeptide Antibiotics.

3. Pharmaceutics i) Liquids (solution, syrup, elixirs, sprits, aromatic water,

liquids for external uses).
ii) Basics of Biostatistics
4. Pharmacognosy Glycosides

5. P’ analysis Proton & C-13 NMR spectrometry

6. P’ Management World trade organization (WTO) and trade related

intellectual property rights (TRIPS)
7. P’ jurisprudence i) Minimum wages act 1948.
ii) Prevention of food adulteration act 1954, and
rules 1955.
 Module -10
S.N. Subject Topic(Details given in the syllabus)

1. Organic chemistry Organometallic chemistry

Reagents used in organic synthesis
2. Pharmacology & ii) Quinolones &sulpha drugs
Medicinal chemistry iii) Antimycobacterial drugs.
iv) Antifungal agents.
v) Antiviral agent including HIV and Anti HIV drugs.
vi) Antimalerial
Medicinal Chemistry Drug-Design (QSAR & Docking studies)

3. Pharmaceutics Prolonged action pharmaceuticals, Opthamic preparation,

4. P’ analysis Mass spectrometry

X-Ray Diffraction method
Circular dichroism
5. Biopharmaceutical and Bio- availability and bio-equivalence & Kinetics principles and
p’ cokinetic stability
6. P’ Management Standard Institutions and regulatory Authorities