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What Is The Difference Between A Vial & An Ampule?

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What Is the Difference Between a Vial & an

Ampule?

Ampule

 An ampule typically indicates a sealed glass container that holds some pharmaceutical
compound. This device is sealed to protect its content from air or humidity. The
closure of the small container results from melting the tip of the ampule. Its opening
requires breaking the neck of the bottle.

Vial

 A vial represents a broader term than an ampule. It includes any small container that
holds pharmaceutical or chemical compounds. Typically made of glass, the vial can
be sealed or not sealed. The vessel closes with a screw on cap, or a rubber plug.
Sometimes, its top includes a dropper to measure the liquid to retrieve. The vial tends
to have a flat bottom so that it can rest on a counter.

Potency Protection

 Chemical elements that tend to be unstable in the presence of air or another compound
remain intact and keep their potency when stored in an ampule. Frequently, drug
manufacturers will pull the air out of an ampule before sealing it to prevent the
medication from degrading within the container. A vial is typically not hermetic and
best contains stable compounds.

Reuse

 Since the ampule opens with a break of its shell, this container is not reusable. At
times, snapping off of the ampule may be challenging and at times present risk of
injury according to Ron Stoker, Executive Director of the International Sharps Injury
Prevention Society. In contrast, a vial can be cleaned and reused several times and
presents less risk of injury.

Volume Measurement

 The container of an ampule experiences slight variations in its internal volume. This
results from the sealing process that melts the glass. Typically, a syringe with volume
indicators pulls some fluid from the ampule to size the required amount of
medication. In contrast, a vial can provide accurate volume markings that become
visual indicator of the remaining volume of product.
Mixing

 Vials act as convenient containers to mix several chemical compounds together.


Through their glass walls, the resulting compounds feature their consistency and
colors. The broken glass edge of opened ampules presents the risk of introducing
small glass debris into a mixture of chemical elements and therefore do not lend
themselves to mixing products.

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