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OPTOMED-HW2-Diabetic Retinopathy PDF

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SALVADOR, DANALIE C.

OD6C

OCULAR MANIFESTATIONS OF DIABETES MELLITUS

DIABETIC RETINOPATHY
- is a complication of diabetes that causes damage to the blood vessels of the retina.
- the primary cause of diabetic retinopathy is diabetes—a condition in which the levels of glucose
(sugar) in the blood are too high. Elevated sugar levels from diabetes can damage the small blood
vessels that nourish the retina and may, in some cases, block them completely.

TYPES OF DIABETIC RETINOPATHY:

A. NON-PROLIFERATIVE DIABETIC RETINOPATHY


Characterized by the following findings:
MICROANEURYSMS INTRARETINAL HEMORRHAGES:
-are the earliest clinically visible Dot/Blot or Splinter
changes of diabetic retinopathy. hemorrhages.
- localised capillary dilatations which -hemorrhage within the
are usually saccular (round). nerve fibre layer tends to
be flame shaped,
following the divergence
of axons.
-in the inner layer,
haemorrhage is aligned at
right angles to the retinal
surface and is
consequently viewed end-on when using an
ophthalmoscope; these haemorrhages appear dot or blot
shaped.
HARD EXUDATES COTTON WOOL SPOTS
-are distinct yellow-white intra-retinal -are greyish-white
deposits which can vary from small patches of discoloration
specks to larger patches in the nerve fibre layer
which have indistinct
(fluffy) edges.
- multiple cotton wool
spots (more than 6 in one
eye) indicate generalised
retinal ischaemia and this
is regarded as a pre-proliferative state

VENOUS ABNORMALITIES INTRARETINAL MICROVASCULAR ABNORMALITIES (IRMAs)


Venous dilatation, beading and -areas of capillary
duplication. dilatation and intraretinal
new vessel formation
-arise within ischaemic
retina and when they are
present in numbers are a
feature of pre-proliferative
retinopathy
B. PROLIFERATIVE DIABETIC RETINOPATHY
Characterized by the following findings:
NEOVASCULARIZATION VITREOUS HEMORRHAGE
-as the retina becomes more ischaemic new -vitreous haemorrhage can give rise to
blood vessels may arise from the optic disc or in profound loss of vision if the macula is
the periphery of the retina. obscured.
1. Neovascularization at the Disc (NVD)
2. Neovascularization Elsewhere (NVE)

TRACTIONAL RETINAL DETACHMENT SUBHYALOID HEMORRHAGE


-as the new vessels mature, connective tissue -where there is localised detachment of the
and fibrosis (gliosis) occurs allowing the vitreous vitreous blood can accumulate between the
to exert traction which may cause retinal retina and the vitreous adopting the
detachment. characteristic appearance of a subhyaloid
haemorrhage.
-this is often said to be boat-shaped (in this
case the boat has clearly capsized).

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