MEDICINAL CHEMISTRY(SEC-B)

Course file
Faculty Name: D.Tirumala
Designation: Assistant professor
Batch: 2017-2021
Academic Year: 2019-20
Semester/Year: III/I
Course Name: Medicinal chemistry-II
Course Code/Regl: C331 /R17
S.No Course File Contents Check List (Yes/No) Remarks

1 Vision & Mission of The Institute Yes

2 Program Educational Objectives And Program Yes
Outcomes
3 JNTUH Academic Calendar And List Of Holidays Yes

4 Syllabus Copy Including Text Books And Reference Yes

Books
5 Personal Time Table Yes
6 Calendar of Events Yes
7 Lesson Plan with methodology being used/adopted Yes
8 Subject Notes Yes
9 Student Name List Yes
10 Attendance Report Yes
11 Content Beyond Syllabus and mapping with POs
12 I, II & III Internal Marks (Theory and Lab) Yes

13 CO Attainment Report NA
14 Action Taken Report
15 JNTUH old Question Paper/Question Bank Yes
16 Internal Test Question Papers (I, II & III Internal Yes
Question Papers/Sub/Obj/Key)
17 Assignment Questions Yes
18 Scheme of Evaluation Yes
19 Identification of Bright Students Yes
20 Identification of Weak Students Yes
21 Remedial Classes Time Table NA
22 Result Analysis NA

Course Teacher HOD Program Coordinator Principal

GEETHANJALI COLLEGE OF PHARMACY

MEDICINAL CHEMISTRY(SEC-B)

1.Vision of the Institute:

To be a Premier Pharmaceutical Education and Research Institution.

Mission of the Institute:

M1: Provide state of the art laboratories, information centre and learning environment for holistic
education.

M2: Adopt and implement best practices for learning and research.

M3: Collaborate with industry and society to identify problems, provide sustainable solutions and align
curriculum.

GEETHANJALI COLLEGE OF PHARMACY

MEDICINAL CHEMISTRY(SEC-B)

2.Program Educational Objectives (PEOs):

PEO-1- KNOWLEDGE
Pharmacy Graduates will have professional & technical career in inter disciplinary domains providing
innovative and eco-friendly sustainable solutions using modern tools.
PEO-2- SKILLS
Pharmacy Graduates will have effective communication, leadership, team building, problem solving,
decision making and creative skills.

PEO-3- ATTITUDE
Pharmacy Graduates will practice ethical responsibilities towards their peers, employer’s, society and
world at large.

PROGRAM OUTCOMES

1. Pharmacy Knowledge: Possess knowledge and comprehension of the core and basic knowledge associated
with the profession of pharmacy, including biomedical sciences; pharmaceutical sciences; behavioral, social,
and administrative pharmacy sciences; and manufacturing practices.

2. Planning Abilities: Demonstrate effective planning abilities including time management, resource
management, delegation skills and organizational skills. Develop and implement plans and organize work to
meet deadlines.

3. Problem analysis: Utilize the principles of scientific enquiry, thinking analytically, clearly and critically, while
solving problems and making decisions during daily practice. Find, analyze, evaluate and apply information
systematically and shall make defensible decisions.

4. Modern tool usage: Learn, select, and apply appropriate methods and procedures, resources, and modern
pharmacy-related computing tools with an understanding of the limitations.

5. Leadership skills: Understand and consider the human reaction to change, motivation issues, leadership and
team-building when planning changes required for fulfillment of practice, professional and societal
responsibilities. Assume participatory roles as responsible citizens or leadership roles when appropriate to
facilitate improvement in health and well-being.

6. Professional Identity: Understand, analyze and communicate the value of their professional roles in society
(e.g. health care professionals, promoters of health, educators, managers, employers, employees).

7. Pharmaceutical Ethics: Honour personal values and apply ethical principles in professional and social
contexts. Demonstrate behavior that recognizes cultural and personal variability in values, communication
and lifestyles. Use ethical frameworks; apply ethical principles while making decisions and take responsibility
for the outcomes associated with the decisions.

8. Communication: Communicate effectively with the pharmacy community and with society at large, such as,
being able to comprehend and write effective reports, make effective presentations and documentation, and
give and receive clear instructions.

9. The Pharmacist and society: Apply reasoning informed by the contextual knowledge to assess societal,
health, safety and legal issues and the consequent responsibilities relevant to the professional pharmacy
practice.

10. Environment and sustainability: Understand the impact of the professional pharmacy solutions in societal
and environmental contexts, and demonstrate the knowledge of, and need for sustainable development.

11. Life-long learning: Recognize the need for, and have the preparation and ability to engage in independent
and life-long learning in the broadest context of technological change. Self-assess and use feedback
effectively from others to identify learning needs and to satisfy these needs on an ongoing basis.

GEETHANJALI COLLEGE OF PHARMACY

MEDICINAL CHEMISTRY(SEC-B)

3. JNTUH ACADAMIC CALENDER

GEETHANJALI COLLEGE OF PHARMACY

MEDICINAL CHEMISTRY(SEC-B)

4. SYLLABUS COPY:

PS501: MEDICINAL CHEMISTRY – II

B.Pharm. III Year I Sem.

UNIT- I 10 Hours
Antihistaminic agents: Histamine, receptors and their distribution in the humanbody
H1–antagonists: Diphenhydramine hydrochloride*, Dimenhydrinate, Doxylamines
succinate, Clemastine fumarate, Diphenylphyraline hydrochloride, Tripelenamine
hydrochloride, Chlorcyclizine hydrochloride, Meclizine hydrochloride, Buclizine
hydrochloride, Chlorpheniramine maleate, Triprolidine hydrochloride*, Phenidamine
tartarate, Promethazine hydrochloride*, Trimeprazine tartrate, Cyproheptadine
hydrochloride, Azatidine maleate, Astemizole, Loratadine, Cetirizine, Levocetrazine
Cromolyn sodium
H2-antagonists: Cimetidine*, Famotidine, Ranitidin.
Gastric Proton pump inhibitors: Omeprazole, Lansoprazole, Rabeprazole,
Pantoprazole Anti-neoplastic agents:
Alkylating agents: Meclorethamine*, Cyclophosphamide, Melphalan,
Chlorambucil, Busulfan, Thiotepa
Antimetabolites: Mercaptopurine*, Thioguanine, Fluorouracil, Floxuridine, Cytarabine,
Methotrexate*, Azathioprine
Antibiotics: Dactinomycin, Daunorubicin, Doxorubicin, Bleomycin
Plant products: Etoposide, Vinblastin sulphate, Vincristin sulphate
Miscellaneous: Cisplatin, Mitotane.

UNIT – II 10 Hours
Anti-anginal:
Vasodilators: Amyl nitrite, Nitroglycerin*, Pentaerythritol tetranitrate, Isosorbide
dinitrite*, Dipyridamole.
Calcium channel blockers: Verapamil, Bepridil hydrochloride, Diltiazem hydrochloride,
Nifedipine, Amlodipine, Felodipine, Nicardipine, Nimodipine.
Diuretics:
Carbonic anhydrase inhibitors: Acetazolamide*, Methazolamide, Dichlorphenamide.
Thiazides: Chlorthiazide*, Hydrochlorothiazide, Hydroflumethiazide, Cyclothiazide,
Loop diuretics: Furosemide*, Bumetanide, Ethacrynic acid.
Potassium sparing Diuretics: Spironolactone, Triamterene, Amiloride.
Osmotic Diuretics: Mannitol
Anti-hypertensive Agents: Timolol, Captopril, Lisinopril, Enalapril, Benazepril hydrochloride, Quinapril

GEETHANJALI COLLEGE OF PHARMACY

MEDICINAL CHEMISTRY(SEC-B)

hydrochloride, Methyldopate hydrochloride,* Clonidine hydrochloride, Guanethidine

monosulphate, Guanabenz acetate, Sodium nitroprusside, Diazoxide, Minoxidil, Reserpine, Hydralazine
hydrochloride

UNIT - III 10 Hours

Anti-arrhythmic Drugs: Quinidine sulphate, Procainamide hydrochloride, Disopyramide phosphate*,
Phenytoin sodium, Lidocaine hydrochloride, Tocainide hydrochloride, Mexiletine hydrochloride,
Lorcainide hydrochloride, Amiodarone, Sotalol.
Anti-hyperlipidemic agents: Clofibrate, Lovastatin, Cholesteramine and Cholestipol
Coagulant & Anticoagulants: Menadione, Acetomenadione, Warfarin*, Anisindione, clopidogrel
Drugs used in Congestive Heart Failure: Digoxin, Digitoxin, Nesiritide
Bosentan, Tezosentan.

UNIT - IV 08 Hours
Drugs acting on Endocrine system
Nomenclature, Stereochemistry and metabolism of steroids
Sex hormones: Testosterone, Nandralone, Progestrones, Oestriol, Oestradiol,
Oestrione, Diethyl stilbestrol.
Drugs for erectile dysfunction: Sildenafil, Tadalafil.
Oral contraceptives: Mifepristone, Norgestril, Levonorgestrol
Corticosteroids: Cortisone, Hydrocortisone, Prednisolone, Betamethasone, Dexamethasone
Thyroid and antithyroid drugs: L-Thyroxine, L-Thyronine, Propylthiouracil, Methimazole.

UNIT – V 07 Hours
Antidiabetic agents:
Insulin and its preparations
Sulfonyl ureas: Tolbutamide*, Chlorpropamide, Glipizide, Glimepiride.
Biguanides: Metformin.
Thiazolidinediones: Pioglitazone, Rosiglitazone.
Meglitinides: Repaglinide, Nateglinide.
Glucosidase inhibitors: Acarbose, Voglibose.
Local Anesthetics: SAR of Local anesthetics
Benzoic Acid derivatives; Cocaine, Hexylcaine, Meprylcaine, Cyclomethycaine,
Piperocaine. Amino Benzoic acid derivatives: Benzocaine*, Butamben, Procaine*,
Butacaine, Propoxycaine, Tetracaine, Benoxinate.
Lidocaine/Anilide derivatives: Lignocaine, Mepivacaine, Prilocaine, Etidocaine.
Miscellaneous: Phenacaine, Diperodon, Dibucaine.*

Recommended Books (Latest Editions)

1. Wilson and Giswold’s Organic medicinal and Pharmaceutical Chemistry.
2. Foye’s Principles of Medicinal Chemistry.
3. Burger’s Medicinal Chemistry, Vol I to IV.
4. Introduction to principles of drug design- Smith and Williams.
5. Remington’s Pharmaceutical Sciences.
6. Martindale’s extra pharmacopoeia.
7. Organic Chemistry by I.L. Finar, Vol. II.
8. The Organic Chemistry of Drug Synthesis by Lednicer, Vol. 1to 5.
9. Indian Pharmacopoeia.
Text book of practical organic chemistry- A.I.Vogel

GEETHANJALI COLLEGE OF PHARMACY

MEDICINAL CHEMISTRY(SEC-B)

5. Personal Timetable

B.Pharmacy III year I sem section-B

Time 9.00- 9.50- 10.40- 11.30- 12.20- 1.00- 1.50- 2.40-3.30

9.50 10.40 11.30 12.20 1.00 1.50 2.40

Period 1 2 3 4 5 6 7

Mon MC-II Lunch MC-II

Break
Tues MC-II

Wed MC-II

Thurs

Fri

Sat

GEETHANJALI COLLEGE OF PHARMACY

MEDICINAL CHEMISTRY-II(SEC-B)

6.CALENDER OF EVENTS

GEETHANJALI COLLEGE OF PHARMACY

MEDICINAL CHEMISTRY-II(SEC-B)

Month Monday Tuesday Wednesday Thursday Friday Saturday Sunday

15 16 17 18 19 20 21
Commencement
of Instruction
22 23 24 25 26 27 28
Bonalu

29 30 31 - - - -
July’2019
Aug’2019 - - - 1 2 3 4

5 6 7 8 9 10 11

12 13 14 15 16 17 18
Bakrid Independence
Day
19 20 21 22 23 24 25
Krishnastami
26 27 28 29 30 31 -

Orientation
day
Sep’2019 - - - - - - 1

2 3 4 5 6 7 8
Vinayakachavithi Teachers Day
9 10 11 12 13 14 15
Moharam Nimajjanam Ist Mid Term Examination

16 17 18 19 20 21 22

23 24 25 26 27 28 29
Pharmacist Bathukamma
day
celebrations
30 - - - - - -

Oct’2019 - 1 2 3 4 5 6
Gandhi Bathukamma
Jayanthi Celebrations

7 8 9 10 13
11 12
Dussehra Holidays

14 15 16 17 18 19 20

21 22 23 24 25 26 27

28 29 30 31 - - -

- - - - 1 2 3

4 5 6 7 8 9 10

11 12 13 14 15 16 17
Gurunanak Dravyaka
Jayanthi
18 19 20 21 22 24
23
IInd Mid Term Examination
Nov’2019

GEETHANJALI COLLEGE OF PHARMACY

MEDICINAL CHEMISTRY-II(SEC-B)

7. LESSON PLAN WITH METHODOLOGY BEING USED/ADOPTED:

III-I SEC-B

S.NO TOPICS TO BE COVERED

No of Proposed date Actual date

classe
s
UNIT-1
1 2 Introduction to Medicinal chemistry 15-7-2019 15-7-2019
2 1 Histamine introduction &its receptors in body 16-7-2019 16-7-2019
3 1 Antihistamines Classification 17-7-2019 17-7-2019

4 2 Synthesis and S.A.R ,uses of H1 antagonists 22-7-2019 22-7-2019

5 1 H1, H2 antagonists structures 23-7-2019 23-7-2019
6 1 Synthesis, sar,uses of H2 antagonists 24-7-2019 24-7-2019
7 1 Proton pump inhibitors 30-7-2019 30-7-2019
8 1 Antineoplastic agents introduction, classification 31-7-2019 31-7-2019

9 2 Synthesis of Methotrexate,Mercaptopurine, 5-8-2019 5-8-2019

Mechlorithamine
10 1 Structures ,uses of other agents 6-8-2019 6-8-2019

11 1 Structures ,uses of other agents 7-8-2019 7-8-2019

12 1 Mechanism of action of Antineoplastic agents 13-8-2019 13-8-2019

Vasodilators
13 1 Mechanism of action of Antineoplastic agents 14-8-2019 14-8-2019
UNIT-2
14 2 Vasodilators 19-8-2019 19-8-2019
15 1 Calcium channel blockers introduction ,classification 20-8-2019 20-8-2019
16 1 Synthesis ,sar,uses of Calcium channel blockers 21-8-2019 21-8-2019
17 1 Synthesis ,sar,uses of Calcium channel blockers 26-8-2019 26-8-2019
18 1 Diuretics introduction, classification 26-8-2019 26-8-2019
19 1 Thaizide diuretics Synthesis ,M.o.a 27-8-2019 27-8-2019
20 1 Synthesis of Acetazolamide,moa 2-9-2019 2-9-2019
21 1 Introduction ,classification of anti hypertensive agents 3-9-2019 3-9-2019

22 1 Synthesis of Methyldopa, structure of other drugs 4-9-2019 4-9-2019

23 2 Moa of ace inhibitors,angiotensin-I antagonists 9-9-2019 9-9-2019

UNIT-3
24 1 Anti arrhythmic agents 11-9-2019 11-9-2019
25 2 First internal exam 16-9-2019 16-9-2019
26 2 Moa ,structure, uses of Anti arrhythmic agents 23-9-2019 23-9-2019

27 1 Antihyperlipidemic agents 24-9-2019 24-9-2019

28 2 Anticoagulants classification ,synthesis of warfarin 30-9-2019 30-9-2019

Structure,m.o.a,uses of anticoagulants, 30-9-2019 30-9-2019

Congestive heart failure drugs

GEETHANJALI COLLEGE OF PHARMACY

MEDICINAL CHEMISTRY-II(SEC-B)

29 1 Slip test 1-10-2019 1-10-2019

UNIT-4
30 2 Nomenclature, introduction and stereochemistry of 21-10-2019 21-10-2019
steroids
31 1 Testosterone,nandralone ,Progesterone 22-10-2019 22-10-2019
32 1 Ostradiol,Oestrione,Diethyl stilbestrol 23-10-2019 23-10-2019
33 Drugs for erectile disfunction 28-10-2019 28-10-2019
2 Oral contraceptives
34 1 Corticosteroids, Thyroid and anti thyroid drugs 29-10-2019 29-10-2019

UNIT-5
35 1 Insulin and its preparations,sulfonyl ureas 30-10-2019 30-10-2019
36 2
Biguanidines,Thaizolinediones, Metaglitinides 4-11-2019 4-11-2019

37 1 Glucosidase inhibitors, moa, S.A.R of Local 5-11-2019 5-11-2019

anesthetics
38 1 Slip test 6-11-2019 6-11-2019
39 2 P-AminoBenzoic acid,Benzoic acid derivatives 11-11-2019 11-11-2019

40 1 Lidocaine derivatives,moa of local anesthetics 12-11-2019 12-11-2019

41 2 Synthesis of procaine ,Benzocaine,Dibucaine 18-11-2019 18-11-2019

42 1 Miscellaneous local anesthetics 19-11-2019 19-11-2019

43 1 Revision 20-11-2019 20-11-2019

8.COURSE NOTES

Soft and hard copy available

GEETHANJALI COLLEGE OF PHARMACY

MEDICINAL CHEMISTRY-II(SEC-B)

9. STUDENT LIST:

B.Pharmacy, III yearI sem sec –A

S.No HTNO Name of the Student

1 17FA1R0001 GUDEPU DIVYA

2 17FA1R0003 JERRYPOTHULA PRANITHA
3 17Z51R0043 AKULA SIVASAI
4 17Z51R0044 ARELLA SAHANA SREE
5 17Z51R0045 B HARSHITH REDDY
6 17Z51R0046 B. SAI PRASANNA
7 17Z51R0047 BANOTHU ANKITHA
8 17Z51R0048 BOTTA SUPRIYA
9 17Z51R0049 C.N.B.S. VEDA SAMHITH
10 17Z51R0050 CHALLA VENKATA DHARANI
11 17Z51R0051 D AISWARYA
12 17Z51R0052 DEVARSHETTY SHREYA
13 17Z51R0053 DWARAMPUDI HARSHITA
14 17Z51R0054 GUNDAM MOUNIKA
15 17Z51R0055 J SUCHITHA
16 17Z51R0056 KANKANALA RAGHU
17 17Z51R0057 KHALEDA AFROZE
18 17Z51R0058 KONDA AKHILA
19 17Z51R0059 KOTHAPALLI SNEHA
20 17Z51R0060 KRUTHI T
21 17Z51R0061 KUNCHEPU ANIL
22 17Z51R0062 LACHUBUKTHA LEKHA
23 17Z51R0063 M MRUDULA GAYATHRI
24 17Z51R0064 MADHIREDDY SRIJA REDDY
25 17Z51R0065 MANDALAPARTHI AKHILESH
26 17Z51R0067 MOHAMMED SAMREEN BEGUM
27 17Z51R0068 MOKA PRISCILLA
28 17Z51R0069 NUTHULAPATI VARSHA
29 17Z51R0070 P SWAPNA

GEETHANJALI COLLEGE OF PHARMACY

MEDICINAL CHEMISTRY-II(SEC-B)

30 17Z51R0071 PAILLA MADHURI

31 17Z51R0072 POOJITHA PINJALA
32 17Z51R0073 R POOJA SREE
33 17Z51R0074 RIMSHA TAHREEM
34 17Z51R0075 SANGAM NANDINI
35 17Z51R0076 SHARIYA FIRDOSE
36 17Z51R0077 SINGARAJU JAHNAVI
37 17Z51R0078 TANDALE VISHAL
38 17Z51R0079 UPPALA POOJA
39 17Z51R0080 VANAPALLI SINDHU
40 17Z51R0081 VOOKANTI SWATHI
41 17Z51R0082 VUNNAVA PRATHYUSHA
YELLU LAKSHMI NARASIMHA
42 17Z51R0083 REDDY
43 17Z51R0084 ADEPU SOWMYA
44 17Z51R0085 SAMA KEERTHI

GEETHANJALI COLLEGE OF PHARMACY

MEDICINAL CHEMISTRY-II(SEC-B)

10. Students attendance report

B.Pharmacy, III yearI sem sec –A

NO OF PERCENTAGE
CLASES
S.No HTNO NO OF CLASES CONDUCTEED ATTENDED

1 17FA1R0001 57 36 63.2
57
2 17FA1R0003 33 57.9
57
3 17Z51R0043 46 80.7
57
4 17Z51R0044 49 86.0
57
5 17Z51R0045 43 75.4
57
6 17Z51R0046 40 70.2
57

7 17Z51R0047 33 57.9
57
8 17Z51R0048 52 91.2
57
9 17Z51R0049 37 64.9
57
10 17Z51R0050 51 89.5
57
11 17Z51R0051 43 75.4
57
12 17Z51R0052 33 57.9
57
13 17Z51R0053 38 66.7
57
14 17Z51R0054 36 63.2
57
15 17Z51R0055 52 91.2
57
16 17Z51R0056 38 66.7
57
17 17Z51R0057 47 82.5
57
18 17Z51R0058 43 75.4
57
19 17Z51R0059 40 70.2
57
20 17Z51R0060 43 75.4
57
21 17Z51R0061 37 64.9
57
22 17Z51R0062 46 80.7
57
23 17Z51R0063 37 64.9

GEETHANJALI COLLEGE OF PHARMACY

MEDICINAL CHEMISTRY-II(SEC-B)

57
24 17Z51R0064 52 91.2
57
25 17Z51R0065 37 64.9
57
26 17Z51R0067 15 26.3
57
27 17Z51R0068 42 73.7
57
28 17Z51R0069 41 71.9
57
29 17Z51R0070 49 86.0
57
30 17Z51R0071 32 56.1
57
31 17Z51R0072 48 84.2
57
32 17Z51R0073 56 98.2
57
33 17Z51R0074 34 59.6
57
34 17Z51R0075 40 70.2
57
35 17Z51R0076 38 66.7
57
36 17Z51R0077 37 64.9
57
37 17Z51R0078 41 71.9
57
38 17Z51R0079 45 78.9
57
39 17Z51R0080 46 80.7
57
40 17Z51R0081 52 91.2
57
41 17Z51R0082 50 87.7
57
42 17Z51R0083 45 78.9
57
43 17Z51R0084 49 86.0
57
44 17Z51R0085 34 59.6
57
44 17FA1R0001 48 84.2

GEETHANJALI COLLEGE OF PHARMACY

 MEDICINAL CHEMISTRY-II(SEC-B)

12.I,II mid marks

S. H.T.NO Name of I INTERNAL II INTERNAL

NO the AS
Student SUB OBJ ASS T SUB OBJ ASS TOTAL AVG I II AVG
(10M) (10M) (5M) 25M (10M) 10M (5M) 25M
GUDEPU
1 17FA1R0001 DIVYA 3.5 1.5 5 10 7 8.5 5 21 15.5 5 5 5
JERRYPO
THULA
PRANITH
2 17FA1R0003 A 3.5 2 5 11 6.5 6 5 18 14.5 5 5 5
AKULA
3 17Z51R0043 SIVASAI 4.5 3.5 5 13 9 5 5 19 16 5 5 5
ARELLA
SAHANA
4 17Z51R0044 SREE 10 5 5 20 9 5 5 19 19.5 5 5 5
B
HARSHIT
5 17Z51R0045 H REDDY 8.5 5 5 19 8 4 5 17 18 5 5 5
B. SAI
PRASAN
6 17Z51R0046 NA 8.5 2.5 5 16 10 4 5 19 17.5 5 5 5
BANOTH
U
7 17Z51R0047 ANKITHA 7.5 5.5 5 18 A A A A 0! A A A

BOTTA
8 17Z51R0048 SUPRIYA 10 6.5 5 22 9 5.5 5 20 21 5 5 5
C.N.B.S.
VEDA
SAMHIT
9 17Z51R0049 H 8 4 5 17 7 0 5 12 14.5 5 5 5
CHALLA
VENKATA
DHARAN
10 17Z51R0050 I 6 2.5 5 14 8 2.5 5 16 15 5 5 5
D
AISWAR
11 17Z51R0051 YA 10 4.5 5 20 10 3 5 18 19 5 5 5
DEVARS
HETTY
12 17Z51R0052 SHREYA 7 3 5 15 7.5 3.5 5 16 15.5 5 5 5
DWARAM
PUDI
HARSHIT
13 17Z51R0053 A 7.5 3 5 16 9 4 5 18 17 5 5 5
GUNDAM
MOUNIK
14 17Z51R0054 A 4 5 5 14 6.5 3.5 5 15 14.5 5 5 5
J
SUCHITH
15 17Z51R0055 A 6 3.5 5 15 8 2 5 15 15 5 5 5
KANKAN
ALA
16 17Z51R0056 RAGHU 9.5 4 5 19 6 4 5 15 17 5 5 5
KHALED
A
17 17Z51R0057 AFROZE 8 4.5 5 18 8 3.5 5 17 17.5 5 5 5
KONDA
18 17Z51R0058 AKHILA 10 6.5 5 22 10 3.5 5 19 20.5 5 5 5
KOTHAP
ALLI
19 17Z51R0059 SNEHA 8 3 5 16 9 3.5 5 17 16.5 5 5 5

GEETHANJALI COLLEGE OF PHARMACY

 MEDICINAL CHEMISTRY-II(SEC-B)

KRUTHI
20 17Z51R0060 T 6.5 4.5 5 16 8 3 5 16 16 5 5 5
KUNCHE
21 17Z51R0061 PU ANIL 7.5 2.5 5 15 9 3 5 17 16 5 5 5
LACHUB
UKTHA
22 17Z51R0062 LEKHA 9 3.5 5 18 7.5 5 5 18 18 5 5 5
M
MRUDUL
A
GAYATH
23 17Z51R0063 RI 6 2.5 5 14 6 4 5 15 14.5 5 5 5
MADHIR
EDDY
SRIJA
24 17Z51R0064 REDDY 10 6.5 5 22 10 3.5 5 19 20.5 5 5 5
MANDAL
APARTHI
AKHILES
25 17Z51R0065 H 7 4.5 5 17 8 3 5 16 16.5 5 5 5
MOHAM
MED
SAMREE
N
26 17Z51R0067 BEGUM 9 5.5 5 20 10 6.5 5 22 21 5 5 5
MOKA
PRISCILL
27 17Z51R0068 A 7 5 5 17 10 7.5 5 23 20 5 5 5
NUTHUL
APATI
28 17Z51R0069 VARSHA 9 6 5 20 10 8 5 23 21.5 5 5 5
P
29 17Z51R0070 SWAPNA 6.5 5.5 5 17 8 8.5 5 22 19.5 5 5 5
PAILLA
MADHUR
30 17Z51R0071 I 10 5 5 20 10 8 5 23 21.5 5 5 5
POOJITH
A
31 17Z51R0072 PINJALA 10 9 5 24 10 8.5 5 24 24 5 5 5
R POOJA
32 17Z51R0073 SREE 5 4.5 5 15 10 7 5 22 18.5 5 5 5
RIMSHA
TAHREE
33 17Z51R0074 M 7.5 4 5 17 8 6 5 19 18 5 5 5

SANGAM
34 17Z51R0075 NANDINI 7.5 4 5 17 6.5 7 5 19 18 5 5 5
SHARIYA
35 17Z51R0076 FIRDOSE 6.5 0.5 5 12 8 7.5 5 21 16.5 5 5 5
SINGARA
JU
36 17Z51R0077 JAHNAVI 6.5 4 5 16 9 8.5 5 23 19.5 5 5 5
TANDALE
37 17Z51R0078 VISHAL 9 5 5 19 10 8.5 5 24 21.5 5 5 5
UPPALA
38 17Z51R0079 POOJA 9 6.5 5 21 9.5 8.5 5 23 22 5 5 5
VANAPAL
LI
39 17Z51R0080 SINDHU 10 8 5 23 10 9 5 24 23.5 5 5 5
VOOKAN
TI
40 17Z51R0081 SWATHI 9.5 8.5 5 23 10 8.5 5 24 23.5 5 5 5
VUNNAV
41 17Z51R0082 A 10 6 5 21 10 7.5 5 23 22 5 5 5

GEETHANJALI COLLEGE OF PHARMACY

 MEDICINAL CHEMISTRY-II(SEC-B)

PRATHYU
SHA
YELLU
LAKSHMI
NARASI
MHA
42 17Z51R0083 REDDY 7.5 5.5 5 18 10 8 5 23 20.5 5 5 5
ADEPU
43 17Z51R0084 SOWMYA 9 6 5 20 7 8 5 10 15 5 5 5
SAMA
44 17Z51R0085 KEERTHI 7.5 5 5 18 10 4.5 5 20 19 5 5 5

GEETHANJALI COLLEGE OF PHARMACY

MEDICINAL CHEMISTRY-II(SEC-B)

15. JNTUH old Question Paper/Question Bank

Code No: 216AA R13

JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD
B.Pharmacy III year IISemester Examinations, May-2017
MEDICINAL CHEMISTRY-I
Max.Marks:75
Time: 3hours
Note: This question paper contains two parts A and B.
Part A is compulsory which carries 25 marks. Answer all questions in partA.
Part B consists of 5 units. Answer any one full question from each unit. Each question
carries 10 marks and may have a, b, c as sub questions.
PART- A (25MARKS)
1.
a) Write the major factors governing drug distribution. (2)
b) Discuss the concept of soft drug. (3)
c) Define and classify anti depressants. (2)
d) Write the chemical structure and nomenclature of Diazepam, Carbamazepine and Benzocaine.
(3)
e) Draw the structure and write the stereochemical aspects of Ephedrine. (2)
f) Discuss the basical structural requirements of adrenergic agonists. (3)
g) Write the chemical structure and nomenclature of oxyphenbutazone and diclofenac.
(2)
h) Discuss the functions of prostaglandins. (3)
i) List the clinical uses of diuretics. (2)
j) Write the classification of drugs used in the treatment of angina pectoris. (3)

PART-B (50MARKS)
2.
a) What is drug metabolism? write the factors affecting drug metabolism.
b) Write a note on bioisosterism. (5+5)
OR
3.
a) Discuss the prodrug approach in drug design giving suitable examples.
b) Explain the importance of stereochemistry of drugs on biological activities.
(5+5)
4.
a) Define and classify local anesthetics. Outline the synthesis of procaine.
b) Write the chemical structure, nomenclacture, mode of action and uses of any one antipsychotic
drug. (6+4)
OR
5.
a) Write the definition of anti-epileptics and its chemical classification.
b) Write the chemical structure, nomenclature, synthesis and uses of Ethosuximide.
(3+7)
6.
a) Discuss the SAR of muscarinic agonists .
b) Outline the synthesis of Carbachol. (6+4)
OR
7.
a) What are anti cholinesterases? Give the classification with suitable examples. Write the
mechanism of action of anti cholinesterases.
b) Outline the synthesis of Pyridostigmine. (6+4)
8.
a) Write the chemical classification of NSAIDS with suitable examples.
b) Discuss the synthesis, mechanism of action and stereochemical aspects of Ibuprofen.
(3+7)
OR

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MEDICINAL CHEMISTRY-II(SEC-B)

9.
a) Outline the synthesis of Meperidine.
b) Write a brief account on types of pain and inflammation. (4+6)
10.
a) Discuss the SAR of Benzothiadiazine diuretics.
b) Write the synthesis of procinamide. (6+4)
OR
11.
a) Discuss the mechanism of action and synthesis of Isosorbide dinitrate.
b) Write the steps involved in synthesis of Enalapril. (6+4)

Code No: R7501

JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY, HYDERABAD
III Year B. Pharmacy II Semester Examinations, DEC.-JAN., 2011-2012
MEDICINAL CHEMISTRY-I
Time: 3 hours Max. Marks:
80
Answer any five questions
All questions carry equal marks

1. a) Define the term bio-isosterism. Discuss how bio-isosterism affects biological activity of drug
molecules with the help of suitable examples.
b) Describe a method for the synthesis of Phenobarbitone and mention its mechanism of action and
uses. Label each reactant and the reaction conditions required for the synthesis. [16]

2. a) Classify Local anesthetic agents with one example with chemical structure for each class. Give
the mode of action and uses of local anesthetic agents.
b) Give the synthesis, mechanism of action and uses of carbachol and dicyclomine. Label each
reactant and the reaction conditions required for synthesis. [16]

3. a) Discuss the role of cytochrome P-450 and monooxygenases in biotransformation of drug

molecules.
b) Give the synthesis, mechanism of action and uses of chlorpromazine and pyridostygmine. Label
each reactant and the reaction conditions required for synthesis. [16]

4. a) Classify anti-epileptic agents with one example with chemical structure for each class. Give the
mode of action and uses of anti-epileptic agents.
b) Describe a method for the synthesis of Phenytoin and salbutamol. Label each reactant and the
reaction conditions required for the synthesis. [16]

5. a) Classify adrenergic agents with one example with chemical structure for each class. Give the
mode of action and uses of adrenergic agents.
b) Describe a method for the synthesis of bethanecol and Pralidoxime. Label each reactant and the
reaction conditions required for the synthesis. [16]
6. a) Classify anti-psychotic agents with one example with chemical structure for each class. Give the
mode of action and uses of anti-psychotic agents.
b) Give the synthesis, mechanism of action and uses of Halothane and haloperidol. Label each
reactant and the reaction conditions required for the synthesis. [16]
7. a) Classify general anesthetics with one example with chemical structure for each class. Give the
mode of action and uses of general anesthetics.
b) Give the synthesis, mechanism of action and uses of procaine and succinyl choline. Label each
reactant and the reaction conditions required for the synthesis. [16]
8. Write a note on
a) Effect of hydrogen bonding on biological activity of drugs.
b) Synthesis, mode of action and uses of lignocaine.
c) Conjugation reactions in drug metabolism.
d) soft- drug and pro-dug approach in drug design. [16]

GEETHANJALI COLLEGE OF PHARMACY

MEDICINAL CHEMISTRY-II(SEC-B)

GEETHANJALI COLLEGE OF PHARMACY

MEDICINAL CHEMISTRY-II(SEC-B)

Code No:226AA
JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD
B.Pharmacy III Year II Semester Examinations, December – 2018
MEDICINAL CHEMISTRY – I
Time : 3 hours Max.Marks :
75
Note : This question paper contains two parts A and B
Part A is compulsory which carries 25 marks. Answer all questions in part A
Part B consists of 5 units. Answer any one full question from each unit. Each question
carries 10 marks and may have a,b,c as sub questions.
PART – A (25 Marks)
1.a) Define bio isosterism. (2)
b) Give the role of solubility in drug action. (3)
c) classify anti – epileptics with examples. (2)
d) Write the structures of diazepam, imipramine, and ethosuximide. (3)
e) Define anti choline esterase inhibitors with examples. (2)
f) Classfiy adrenergic drugs. (3)
g) Draw any two structures of COX-2 inhibitors. (2)
h) Write the various types of pain. (3)
i) classify antihypertensives. (2)
j) write the structures of Enalaprill, acetazolamide and isosorbide. (3)

PART - B
(50 Marks)
2. Explain in detail about phase -2 metabolic reaction with examples. (10)
OR
3. Explain in detail about partition coefficient. (10)
4. Explain in detail about neurotransmitters. (10)
OR
5. Classify sedatives and hypnotics.Write the synthesis of imipramine and phenobarbitone. (10)
6. Classify cholinergic drugs with examples and give there structures. (10)
OR
7. Write the synthesis of ephedrine and amphetamine. (10)
8. Explain in detail about the bio synthesis of prostaglandin E1. (10)
OR
9. Classify NSAIDS. Write the SAR of Opiod analgesics. (10)
10. Write short notes on nitrates. (10)
OR
11. Classify diuritics. Write the synthesis of actazolamide and hydrochlorthiazide. (10)

Code No:216AA
JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD
B.Pharmacy III Year II Semester Examinations, October – 2016

MEDICINAL CHEMISTRY – I
Time : 3 hours Max.Marks : 75
Note : This question paper contains two parts A and B
Part A is compulsory which carries 25 marks. Answer all questions in part A
Part B consists of 5 units. Answer any one full question from each unit. Each question
carries 10 marks and may have a,b,c as sub questions.
PART – A
(25 Marks)
1.a) Write about partition –coefficient for biological activity.
b) define metabolism. Write the different metabolic reactions.
c) write the structure and mode of action of alprazolam.
d) give the structure and mechanism of action of thiopental sodium.
e) classify adrenergic blockers and give the significance of adrenergic blockade.
f) Write the structure and mechanism of action of any one neuro muscular blocker.

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MEDICINAL CHEMISTRY-II(SEC-B)

g) write the nomencleature and functions of prostaglandins.

h) explain the types of pain and inflammation.
i) Give the structure and mechanism of action of procainamide.
j) Write the synthesis of isosorbide di nitrate.

PART - B
(50 Marks)
2.a) Explain bio isosterism and steric features of drugs.
b) Discuss the soft drug approach with examples.
OR
3.a) Discuss in detail about phase-2 reactions with examples.
b) Explain in brief about solubility and lipophilicity in bio activity of drugs
4.a) Define anxiolytics. Write the synthesis and mechanism of action of diazepam.
b) classify general anesthetic agents. Give the physiochemical and sterio chemical aspects of
procaine.
OR
5.a) Define and classify antidepressants. Write the synthesis of fluoxetine.
b) Write the SAR and metabolism of local anesthetics.
6.a) Classify anti cholinesterases with examples and write the synthesis of pyridostigmine.
b) Write the SAR and general meachanism of action of anticholinergics.
OR
7.a) write the metabolism and therapeutic uses of ephedrine.
b) Give the synthesis and mechanism of action of ipratropium bromide.
8.a) Discuss the bio synthesis of prostaglandin E1.
b) Classify NSAIDS and give the synthesis of meloxicam

Code No:226AA
Time : 3 hours JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD
Note : This B.Pharmacy III Year II Semester Examinations, December – 2018
question paper contains two parts A and B MEDICINAL CHEMISTRY – I Max.Marks :
Part A is compulsory which carries 75
25 marks. Answer all questions in part A
Part B consists of 5 units. Answer any one full question from each unit. Each question
carries 10 marks and may have a,b,c as sub questions.
PART – A
(25 Marks)
1.a) Define bio isosterism. (2)
b) Give the role of solubility in drug action (3)
c) classify anti – epileptics with examples. (2)
d) Write the structures of diazepam, imipramine, and ethosuximide. (3)
e) Define anti choline esterase inhibitors with examples. (2)
f) Classfiy adrenergic drugs. (3)
g) Draw any two structures of COX-2 inhibitors. (2)
h) Write the various types of pain. (3)
i) classify antihypertensives. (2)
j) write the structures of Enalaprill, acetazolamide and isosorbide. (3)

PART - B
(50 Marks)
2. Explain in detail about phase -2 metabolic reaction with examples. (10)
OR
3. Explain in detail about partition coefficient. (10)
4. Explain in detail about neurotransmitters. (10)
OR
5. Classify sedatives and hypnotics.Write the synthesis of imipramine and phenobarbitone. (10)
6. Classify cholinergic drugs with examples and give there structures. (10)
OR

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MEDICINAL CHEMISTRY –II (SEC-A)

7. Write the synthesis of ephedrine and amphetamine. (10)

8. Explain in detail about the bio synthesis of prostaglandin E1. (10)
OR
9. Classify NSAIDS. Write the SAR of Opiod analgesics. (10)
10. Write short notes on nitrates. (10)
OR
11. Classify diuritics. Write the synthesis of actazolamide and hydrochlorthiazide. (10)

GEETHANJALI COLLEGE OF PHARMACY

 16. INTERNAL QUESTION PAPERS

Faculty Name: D.Tirumala Designation: Asst. Professor

Year/Sem
Batch: 2017-21 Academic Year: 2019-20 III/I/A&B
/Section

Course Name: Medicinal Chemistry- II Internal Exam: I

Course Maximum
R17 10
Code/Regl: Marks:

Answer any TWO questions

Max. CO
Q. No Question KL
Marks No

Write the Classification of antihistamines and write the structures K1

1a
of Triprolidine hydrochloride,Diphenhydramine hydrochloride (3M) 5 CO1
1b Write the synthesis of Mechlorithamine (2M)
2 Write the synthesis, moa ,uses of Methotrexate(5M) 5 CO1 K1

3a Explain the SAR ,uses of Furosemide(2) K2

5 CO2
3b Explain the SAR ,MOA of Acetazolamide (3)

Define Vasodilators , Write the structures of Nitroglycerin, K1

4a 2.5 CO2
Isosorbide dinitrate.(2)
4b Write the synthesis ,uses of Disopyramide phosphate(3) 2.5 CO3 K1

Note: Internal splitting of questions depends on the subject. Each question may be subdivided into
maximum of two sub questions
CO- Course Outcome (1to5); KL- Blooms knowledge Level (K1, K2, K3, K4, K5, K6)
K1 – Remember K2 – Understand K3 – Apply K4 – Analyze K5 – Evaluate K6 – Create
 B. Pharmacy III- Year I-Sem, Sec-A & B I-Mid Term Exam, September-2019 Medicinal
Chemistry- II - OBJECTIVE EXAM
Name: ______________________________ Hall Ticket No.________________
Answer All Questions. All Questions Carry Equal Marks. Time: 20 Min. Marks: 10

Choose the correct alternative:

H1 antihistamines used for motion sickness and nausea include

1. ( )

a) Diphenhydramine and meclizine b) Toradol and meclizine

c) Epinephrine and loratidine d) Loratidine

2. Which of the following is an antitumor antibiotics ( )

a) Cisplatin b) Cyclophosphamide

c) Chlorambucil d) Doxorubicin

3. Antianginal drug administered by inhalation ( )

a) Isosorbide dinitrate b) Nicorandil

c) Amylnitrite d) Dipyridamole

4. Class –II Antiarrythmic agent ( )

a) Atropine b) Esmolol

c) Lidocaine d) Adenosine

5. Which of the following drug is a carbonic anhydrase inhibitor ( )

a) Mannitol b) Amiloride

c) Acetazolamide d) Vaptans

Which drug reduces the active Cl reabsorption in ascending loop of henle?

6. ( )
Mannitol
a) Spironolactone b)

c) Conivaptan d) Furosemide

7. The following is an alpha adrenergic bloker ( )

a) Prazosin b) Clonidine

c) Labetalol d) Atenolol

8. Fluorouracil is an ( )
a) Purine analogue b) Pyrimidine analogue

c) Folic acid analogue d) antibiotic

9. The fallowing drug is an 1,4 -Dihydro pyridine derivative used as calcium channel blocker ( )
 a) Verapamil b) Bepridil

c) Diltiazem d) Nimodipine

10.
Sodium nitroprusside is a ( )
a) Vasodilator b) Diuretic

c) Calcium channel bloker d) Antihistamine

II. Fill in the Blanks

11. Drugs used in the treatment of peptic ulcers are…………………………….Antagonists

12. Alkaloidal agents that are acting as antineoplasic agents……………………

13. Losartan is an --------------- antagonist

14. Captopril is an………………inhibitor

15. Methyldopa is an example of …………used as an antihypertensive agent

16. Proton pump inhibitors act by inhibiting……………………..enzyme system

17. Thaiazide diuretics enhance urinary secretion by inhibiting………….reabsorption

18. Acetazolamide,Methazolabide are structurally………………………………..derivatives

19. Spiranolactone is used as a diuretic by showing against action to ………………………….

20. Rantidine is a …………………receptor antagonist

KEYS

1. A

2. D

3. A

4. B

5. C

6. D

7. A

8. B

9. D

10. A

11. H2 antagonists

12. Vincristine, Vinblastine

13. Angiotensin

14. ACE

15. Centrally acting sympatholytic agent

16. H+K+ATPase

17. Na+

18. Heterocyclic sulphonamide

19. Aldosterone

20. H2
Biochemistry (sec-A)

Faculty Name: D.Tirumala Designation: Asst. Professor

Year/Sem
Batch: 2017-21 Academic Year: 2019-20 III/I/A&B
/Section

Course Name: Medicinal Chemistry- II Internal Exam: II

Course Maximum
R17 10
Code/Regl: Marks:

Answer any TWO questions

Max. CO
Q. No Question KL
Marks No

Write the Classification of Anticoagulants and write the

1a
synthesis and uses of warfarin(3) 5 CO3 K1
1b Write the structure and uses of Digoxin,Digitoxin (2)
Write the structures and uses of K1
2a Testosterone,Progesterone,Cortisone,Estriol(3) 5 CO4

Write the classification of Anti thyroid drugs,and explain the

2b M.O.A and uses of Propylthiouracil,Methimazole(3)

3a Explain the S.A.R. of local anesthetic agents(3M)

5 CO5 K2
3b Explain briefly about insulin preparations(3)

4a Write the Synthesis of Dibucaine(2) 5 CO5 K1

4b Write the synthesis ,uses of Tolbutamide(3)

Note: Internal splitting of questions depends on the subject. Each question may be subdivided into
maximum of two sub questions
CO- Course Outcome (1to5); KL- Blooms knowledge Level (K1, K2, K3, K4, K5, K6)
K1 – Remember K2 – Understand K3 – Apply K4 – Analyze K5 – Evaluate K6 – Create

GEETHANJALI COLLEGE OF PHARMACY

Biochemistry (sec-A)

B. Pharmacy III- Year I-Sem, Sec-A & B II-Mid Term Exam, November-2019 Medicinal
Chemistry- II - OBJECTIVE EXAM
Name: ______________________________ Hall Ticket No.________________
Answer All Questions. All Questions Carry Equal Marks. Time: 20 Min. Marks: 10

Choose the correct alternative:

Example of Amide based local anesthetic agent

1. ( )

a) Benzocaine b) Procaine

c) Cocaine d) Lidocaine

2. Sodium citrate,sodium oxalate are the …………..anticoagulants ( )

a) In vivo b) In vitro

c) Both in vitro and in vivo d) None of the above

3. Iodides act by inhibiting ( )

a) Inhibits peroxidase enzyme b) Inhibits the conversion of T3to T4

c) Decreases thyroid vascularity d) Inhibits the transport of iodine

4. Example of Natural androgens ( )

a) Testosterone b) Dehydroepiandrosterone

c) Both A and B d) Nandrolone

5. Sterols posses common basic structure ( )

a) b) Cyclopentano perhydrophenanthrene
Tetra cyclic dinaphthalene nuclues nuclues
Cyclohexano perhydrophenanthrene
c) d) Tricyclic anthracene nuclues
nuclues

In cardiac glycosides the sugar portion is responsible for

6. ( )

a) Cardio tonic activity b) Longer durationof action

c) Stability of cardiac glycoside d) Provides favorable solubility and distribution

7. Fallowing drug is an example of glucosidase inhibitor ( )

a) Pioglitazone b) Metformin

c) Acarbose d) Glipizide

8. Which type of local anesthetics have shorter duration of action ( )

a) Amide type local anesthetics b) Ester type local anesthetics
Amino ether based local anesthetics
c) d) Alcohol based local anesthetics

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 Biochemistry (sec-A)

9. Examples of ionic inhibitors ( )

a) SCN- b) ClO4 -

c) Both A and B d) 131 I

10.
Drugs used in graves disease ( )
a) Thyroxin b) Levothyronin

c) T4 d) Propylthiouracil

II. Fill in the Blanks

11. Steroidal hormones in mammals biosynthesized from…………………………….

12. Humulin N is ……………………acting insulin

13. When the ring is enlarged in steroids in nomenclature indicated by ---------------

The pKa value of local anesthetic lie between...........…

14.

15. Colestepol is a example of …………

16. Tolbutamide is ……………………..derivative

17. Lovastatin act by inhibiting…………………………..enzyme

18. Warfarin is a……………derivative

19. Quinidine acts as a antiarrythmic agent by inhibiting…………channel

20. Sidenafil is the drug used in………………

KEYS

1. D

2. B

3. C

4. C

5. B

6. D

7. C

8. B

9. C

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Biochemistry (sec-A)

10. D

11.Cholesterol

12. Intermediate acting

13.Homo

14. 7.5-9.5

15. Antihyperlipidemic agent

16. Sulfonyl urea

17.HMG CoA-reductase

18. Coumarin

19. Na

20. Erectile dysfunction

GEETHANJALI COLLEGE OF PHARMACY

Biochemistry (sec-A)

17. Assignment questions

Unit-1
1. Write the sar ,moa,uses ,synthesis of cimentidine,triprolidine hydrochloride,promethazine
hydrochloride
2. Give the sar ofalkylating agents.,antimetabolites
3. Write a short notes onhistamine receptors and their distribution in the body
4. Define proton pump inhibitors and give any two drug structures along with moa and uses
5. a) Classify anti cancer agents
b). Mention any two plant product antineoplastic agents structures&cisplatin structure

Unit-II
1. Write a note on diuretics with example, write the synthesis of acetazolamide,furosemide
2. Classify diuretics,write the structure of verapamil,nifedipine,reserpine,minoxidil
3. a).enumerate vasodilators ,give the structure of diltiazim
b).Give the sar ,m.o.a structure and uses of amolodipine,hydrochlorthaizide
4. Write down the m.o.a and s.a.r of loop diuretics
5. Write down the m.o.a and s.a.r,uses of carbonic anhydrase inhibitors

Unit-III
1. Define and classify a note on antihyperlipedemic agents with structure
2. Classiify anticoagulants ,write the structure and uses of clofibrate
3. Give an acouunt on statins including moa ,write the structure of lovastatin,lidocaine,amilodarone
4. Classify antiarrythmic agents and give the synthesis and s.a.r of disopyramide phosphate
5. Write the moa and uses ,synthesis of warfarin
6. What is congestive heart failure ,classification,general m.o.a of cardiac glycosides

Unit-IV
1. Explain the nomenclature and chemistry,metabolism of steroids
2. Write a note on oral contraceptives with examples
3. Clasify thyroid and antithyroid drugs with examples ,and give the structure and m.o.a of
methimazole,propylthiouracil
4. Give the detailed account on corticosteroids along with structure of any two drugs .
5. Write down the structure and uses of cortisone ,nandralone,

Unit-V
1. Write a note on hypoglycemic agents,and synthesis of tolbutamide
2. Give the structure of metformin,mention the drugs used in pancreatic malfunctioning
3. Write a short notes on anti diabetic agents,and give the structure of pioglitazone,rosiglitazone
4. Describe the structure, m.o.a and uses of ailpha glucoside inhibitors
5. Give the sar of local anesthetic agents
6. Write the m.o.a ,uses,synthesis of benzocaine,procaine,dibucaine

GEETHANJALI COLLEGE OF PHARMACY

Biochemistry (sec-A)

18. Scheme of evaluation

PARTICULAR WEIGHTAGE MARKS

End Examinations 75% 75
Two Sessionals 20% 20
Assignment 5% 5

GEETHANJALI COLLEGE OF PHARMACY

Biochemistry (sec-A)

19. Identification of Bright students

Hall ticket Number Name

17Z51R0072 Poojitha pinjala

17Z51R0064 Madhir reddy srja reddy

17Z51R0058 Konda akhila
Mohhammed sammren
17Z51R0067 begum

17Z51R0071 Pailla madhuri

GEETHANJALI COLLEGE OF PHARMACY

Biochemistry (sec-A)

20. Identification of Weak Students

Hall ticket Number Name

C.N.B.S. VEDA
17Z51R0049 SAMHITH

17Z51R0063 M MRUDULA GAYATHRI

17Z51R0073 R POOJA SREE

MANDALAPARTHI
17Z51R0065 AKHILESH

17Z51R0066 MANGA MAHESH

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