Health Sciences, 29 (1) : 877-886.: References
Health Sciences, 29 (1) : 877-886.: References
Health Sciences, 29 (1) : 877-886.: References
Abebe, M., Adane, T., Kefyalew, K., Munduno, T., Fasil, A., Biadgo, B.,
Ambachew, S. & Shahnawaz, S. 2019. Variation of Urine Parameters
among Diabetic Patients: A Cross-Sectional Study. Ethiopian journal of
health sciences, 29(1): 877–886.
Abdul-Ghani, M.A. & Defronzo, R.A. 2010. Pathogenesis of insulin resistance in
skeletal muscle. Journal of Biomedicine and Biotechnology, 2010.
doi:10.1155/2010/476279.
Review
Abdelmegeed, M.A., Ha, S., Choi, Y., Akbar, M. & Song, B. 2017. Role of
CYP2E1 in mitochondrial dysfunction and hepatic tissue injury in alcoholic
and non-alcoholic diseases. Curr Mol Pharmacol, 10(3): 207–225.
Alwahsh, S.M. & Gebhardt, R. 2017. Dietary fructose as a risk factor for non-
alcoholic fatty liver disease (NAFLD). Archives of Toxicology, 91(4): 1545–
1563.
American Diabetes Association. 2013. Standards of Medical Care in Diabetes—
2013. Diabetes Care, 36(Supplement 1): S11-S66.
Ardon, O., Procter, M., Tvrdik, T., Longo, N. & Mao, R. 2014. Sequencing
analysis of insulin receptor defects and detection of two novel mutations in
INSR gene. Molecular Genetics and Metabolism Reports, 1(1): 71–84.
http://dx.doi.org/10.1016/j.ymgmr.2013.12.006.
Arner, P. 2015. Fatty Acids , Obesity and Insulin Resistance. The European
Journal of Obesity, 2015: 147–155.
Atmarita, Imanningsih, N., Jahari, A.B., Permaesih, I.D., Chan, P. & Amarra,
M.S. 2018. Consumption and sources of added sugar in Indonesia: A
review. Asia Pacific Journal of Clinical Nutrition, 27(1): 47–64.
Asadipooya, K., Lankarani, K.B., Raj, R. & Kalantarhormozi, M. 2019. RAGE is
a Potential Cause of Onset and Progression of Nonalcoholic Fatty Liver
Disease, International Journal of Endocrinology.
Avari, P. & Devendra, S. 2017. Human immunodeficiency virus and type 2
diabetes. London Journal of Primary Care, 9(3): 38–42.
http://dx.doi.org/10.1080/17571472.2017.1302872.
Bantle, J.P., Raatz, S.K., Thomas, W. & Georgopoulos, A. 2000. Effects of
dietary fructose on plasma lipids in healthy subjects. American Journal of
Clinical Nutrition, 72(5): 1128–1134.
Benedict, M., Zhang, X., Benedict, M. & Zhang, X. 2017. Non-alcoholic fatty
liver disease : An expanded review. World J Hepatol, 9(16): 715–732.
Banerjee, R.R., Rangwala, S.M., Shapiro, J.S., Rich, A.S., Rhoades, B., Qi, Y.,
Wang, J., Rajala, M.W., Pocai, A., Scherer, P.E., Steppan, C.M., Ahima,
R.S., Obici, S., Rossetti, L. & Lazar, M.A. 2004. Regulation of Fasted
Blood Glucose by Resistin. Science, 303(5661): 1195–1198.
Benomar, Y., Gertler, A., De Lacy, P., Crépin, D., Hamouda, H.O., Riffault, L. &
Taouis, M. 2013. Central resistin overexposure induces insulin resistance
through toll-like receptor 4. Diabetes, 62(1): 102–144.
Bhatt, H.B. & Smith, R.J. 2015. Fatty liver disease in diabetes mellitus. Hepato
Biliary Surg Nutr, 4(2): 101–108.
Birnbaum, M.J. 2001. Turning down insulin signaling. Journal of Clinical
Investigation, 108(5): 655–659.
Boucher, J., Kleinridders, A. & Kahn, C.R. 2014. Insulin Receptor Signaling in
Normal. Cold Spring Harb Perspect Biol 2014, 6: a009191.
Bogan, J. S. 2012. Regulation of Glucose Transporter Translocation in Health and
Diabetes. Annual Review of Biochemistry, 81(1), 507–532.
doi:10.1146/annurev-biochem-060109-094246.
Bray, G.A., Nielsen, S.J. & Popkin, B.M. 2004. Consumption of high-fructose
corn syrup in beverages may play a role in the epidemic of obesity.
American Journal of Clinical Nutrition, 79(4): 537–543.
Bugianesi, E ., McCullough, A. J., Marchesini, G. 2005. Insulin resistance: a
metabolic pathway to chronic liver disease. Hepatology, 42 : 987 – 1000.
Calvo-Ochoa, E., Hernández-Ortega, K., Ferrera, P., Morimoto, S. & Arias, C.
2014. Short-term high-fat-and-fructose feeding produces insulin signaling
alterations accompanied by neurite and synaptic reduction and astroglial
activation in the rat hippocampus. Journal of Cerebral Blood Flow and
Metabolism, 34(6): 1001–1008.
Campos, V.C. & Tappy, L. 2016. Physiological handling of dietary fructose-
containing sugars: Implications for health. International Journal of Obesity,
40(S1): S6–S11. http://dx.doi.org/10.1038/ijo.2016.8.
Cantoral, A., Contreras-Manzano, A., Luna-Villa, L., Batis, C., Roldán-Valadez,
E.A., Ettinger, A.S., Mercado, A., Peterson, K.E., Téllez-Rojo, M.M. &
Rivera, J.A. 2019. Dietary sources of fructose and its association with fatty
liver in mexican young adults. Nutrients, 11(3): 1–14.
Censi, S., Mian, C. & Betterle, C. 2018. Insulin autoimmune syndrome: from
diagnosis to clinical management. Annals of Translational Medicine, 6(17):
335–335.
Chalasani, N., Younossi, Z., Lavine, J.E., Diehl, A.M., Brunt, E.M., Cusi, K.,
Charlton, M. & Sanyal, A.J. & the American Gastroenterological
Association, and the American Association for the Study of Liver Diseases,
and the American College of Gastroenterologyh. 2012. The diagnosis and
management of non-alcoholic fatty liver disease: practice guideline by the
American Gastroenterological Association, American Association for the
Study of Liver Diseases, and American College of Gastroenterology.
Gastroenterology, 142: 1592–609.
Chao, H.W., Chao, S.W., Lin, H., Ku, H.C. & Cheng, C.F. 2019. Homeostasis of
glucose and lipid in non-alcoholic fatty liver disease. International Journal
of Molecular Sciences, 20(2).
Chen, C., Jiang, J., Lü, J.M., Chai, H., Wang, X., Lin, P.H. & Yao, Q. 2010.
Resistin decreases expression of endothelial nitric oxide synthase through
oxidative stress in human coronary artery endothelial cells. American
Journal of Physiology - Heart and Circulatory Physiology, 299:193–201.
Chen, M.I., Wu, L., Wu, F., Wittert, G.A., Norman, R.J., Robker, R.L. &
Heilbronn, L.K. 2014. Impaired glucose metabolism in response to high fat
diet in female mice conceived by in vitro fertilization (IVF) or ovarian
stimulation alone. PLoS ONE, 9(11)
Chuah Y. K., Basir R., Talib H., Tie T. H., Nordin N. 2013. Receptor for
advanced glycation end products and its involvement in inflammatory
diseases. International Journal of Inflammation. 2013:15. doi:
10.1155/2013/403460.403460.
Codoñer-Franch, P. & Alonso-Iglesias, E. 2015. Resistin: Insulin resistance to
malignancy. Clinica Chimica Acta, 438: 46–54.
http://dx.doi.org/10.1016/j.cca.2014.07.043.
Coelho, D.F., Pereira-Lancha, L.O., Chaves, D.S., Diwan, D., Ferraz, R., Campos-
Ferraz, P.L., Poortmans, J.R. & Lancha, A.H. 2011. Effect of high-fat diets
on body composition, lipid metabolism and insulin sensitivity, and the role
of exercise on these parameters. Brazilian Journal of Medical and
Biological Research, 44(10): 966–972.
Costandi, J., Melone, M., Zhao, A. & Rashid, S. 2011. Human resistin stimulates
hepatic overproduction of atherogenic ApoB-containing lipoprotein
particles by enhancing ApoB stability and impairing intracellular insulin
signaling. Circulation Research, 108(6): 727–742.
Coops, K.D. & White, M.F. 2012. Regulation of insulin sensitivity by
serine/threonine phosphorylation of insulin receptor substrate proteins IRS1
and IRS2. Diabetologia, 55(10): 2565–2582. doi:10.1007/s00125-012-2644-
8.
Dufault, R., Lukiw, W.J., Crider, R., Schnoll, R., Wallinga, D. & Deth, R. 2012.
A macroepigenetic approach to identify factors responsible for the autism
epidemic in the United States. Clinical Epigenetics, 4(1): 6.
Dhamija, E., Paul, S. B., & Kedia, S. 2019. Non-alcoholic fatty liver disease
associated carcinoma: An increasing concern. Indian J Med Res: 9-17.
DiMenna, F.J. & Arad, A.D. 2018. Exercise as ‘precision medicine’ for insulin
resistance and its progression to type 2 diabetes: A research review. BMC
Sports Science, Medicine and Rehabilitation, 10(1): 1–23.
Donnelly, K.L., Smith, C.I., Schwarzenberg, S.J., Jessurun, J., Boldt, M.D. &
Parks, E.J. 2005. Sources of fatty acids stored in liver and secreted via
lipoproteins in patients with nonalcoholic fatty liver disease. Journal of
Clinical Investigation, 115(5): 1343–1351.
Douard, V. & Ferraris, R.P. 2013. The role of fructose transporters in diseases
linked to excessive fructose intake. Journal of Physiology, 591(2): 401–414.
Dresner, A., Laurent, D., Marcucci, M., Griffin, M.E., Dufour, S., Cline, G.W.,
Slezak, L.A., Andersen, D.K., Hundal, R.S., Rothman, D.L., Petersen, K.F.
& Shulman, G.I. 1999. Effects of free fatty acids on glucose transport and
IRS-1-associated phosphatidylinositol 3-kinase activity. Journal of Clinical
Investigation, 103(2): 253–259.
Drewnowski, A. and Almiron-Roig, E. 2010. Chapter 11 Human Perceptions and
Preferences for Fat-Rich Foods. In: Montmayeur, J.P. and Le Coutre, J.,
Eds., Fat Detection: Taste, Texture, and Post Ingestive Effects. CRC Press,
Boca Raton, 265.
El-bashiti, T.A., Zabut, B.M. & Safia, F.F.A.B.U. 2019. Current Research in
Nutrition and Food Science Effect of Probiotic Fermented Milk ( Kefir ) on
Some Blood Biochemical Parameters Among Newly Diagnosed Type 2
Diabetic Adult Males in Gaza Governorate. Current Research in Nutrition
and Food Science, 7(2): 568-575.
Elliott, S.S., Keim, N.L., Stern, J.S., Teff, K. & Havel, P.J. 2002. Fructose, weight
gain, and the insulin resistance syndrome. American Journal of Clinical
Nutrition, 76(5): 911–922.
Erejuwa, O.O. 2012. Management of diabetes mellitus: Could simultaneous
targeting of hyperglycemia and oxidative stress be a better panacea?
International Journal of Molecular Sciences, 13(3): 2965–2972.
Fachruddin, L. 2000. Budi daya kacang-kacangan. Kanisius.Yogyakarta: 53.
Feinman, R.D. & Fine, E.J. 2013. Fructose in perspective. Nutrition and
Metabolism, 10(1).
Ferrante JrAW. 2013. Macrophages, fat, and the emergence of
immunometabolism. J Clin Invest, 123:4992–3.
Fletcher, J.A., Deja, S., Satapati, S., Fu, X., Burgess, S.C. & Browning, J.D. 2019.
Impaired ketogenesis and increased acetyl-CoA oxidation promote
hyperglycemia in human fatty liver. JCI Insight, 4(11): 1–16.
Forbes, J.M., Cooper, M.E., Oldfield, M.D. & Thomas, M.C. 2003. Role of
advanced glycation end products in diabetic nephropathy. Journal of the
American Society of Nephrology, 14(SUPPL. 3): 254–258.
Forrester, S.J., Kikuchi, D.S., Hernandes,M.S., Xu, Q., & Griendling, K.K. 2019.
Reactive Oxygen Species in Metabolic and Inflammatory Signaling. Circ
Res, 16; 122(6): 877–902.
doi:10.1161/CIRCRESAHA.117.311401.
Galderisi, A., Giannini, C., Van Name, M. & Caprio, S. 2019. Fructose
Consumption Contributes to Hyperinsulinemia in Adolescents with Obesity
Through a GLP-1-Mediated Mechanism. Journal of Clinical Endocrinology
and Metabolism, 104(8): 3481–3490.
Gassaway, B.M., Petersen, M.C., Surovtseva, Y. V., Barber, K.W., Sheetz, J.B.,
Aerni, H.R., Merkel, J.S., Samuel, V.T., Shulman, G.I. & Rinehart, J. 2018.
PKCε contributes to lipid-induced insulin resistance through cross talk with
p70S6K and through previously unknown regulators of insulin signaling.
Proceedings of the National Academy of Sciences of the United States of
America, 115(38): E8996–E9005.
Gastaldelli, A. 2017. Insulin resistance and reduced metabolic flexibility : cause or
consequence of NAFLD. Clinical Science, 131 : 2701–2704.
https://doi.org/10.1042/CS20170987.
Geidl-Flueck, B. & Gerber, P.A. 2017. Insights into the hexose liver metabolism
—glucose versus fructose. Nutrients, 9(9).
Gordon, S. 2003. Alternative activation of macrophages. Nature reviews.
Immunology, 3(1): 23–35.
Grundy, S.M., Cleeman, J.I., Daniels, S.R., Donato, K.A., Eckel, R.H., Franklin,
B.A., Gordon, D.J., Krauss, R.M., Savage, P.J., Smith, S.C., Spertus, J.A. &
Costa, F. 2005. Diagnosis and management of the metabolic syndrome: an
American Heart Association/National Heart, Lung, and Blood Institute
Scientific Statement. Circulation, 112(17):2735-2752.
Guerra-Castellano, A., Díaz-Quintana, A., Pérez-Mejías, G., Elena-Real, C.A.,
González-Arzola, K., García-Mauriño, S.M., De la Rosa, M.A. & Díaz-
Moreno, I. 2018. Oxidative stress is tightly regulated by cytochrome c
phosphorylation and respirasome factors in mitochondria. Proceedings of
the National Academy of Sciences of the United States of America, 115(31):
7955–7960.
Guo, S. 2013. Molecular Basis of Insulin Resistance: The Role of IRS and Foxo1
in the Control of Diabetes Mellitus and Its Complications. Drug Discov
Today Dis Mech, 10(1-2): e27–e33. doi:10.1016/j.ddmec.2013.06.003.
Hammoutene, A. & Rautou, P.E. 2019. Role of liver sinusoidal endothelial cells
in non-alcoholic fatty liver disease. Journal of Hepatology, 70(6): 1278–
1291. https://doi.org/10.1016/j.jhep.2019.02.012.
Hannou, S.A., Haslam, D.E., McKeown, N.M. & Herman, M.A. 2018. Fructose
metabolism and metabolic disease. Journal of Clinical Investigation,
128(2): 545–555.
Hatting, M., Tavares, C.D.J., Sharabi, K., Rines, A.K. & Puigserver, P. 2018.
Insulin regulation of gluconeogenesis. Annals of the New York Academy of
Sciences, 1411(1): 21–35.
Haythorne, E., Rohm, M., van de Bunt, M., Brereton, M.F., Tarasov, A.I.,
Blacker, T.S., Sachse, G., Silva dos Santos, M., Terron Exposito, R., Davis,
S., Baba, O., Fischer, R., Duchen, M.R., Rorsman, P., MacRae, J.I. &
Ashcroft, F.M. 2019. Diabetes causes marked inhibition of mitochondrial
metabolism in pancreatic β-cells. Nature Communications, 10(1).
http://dx.doi.org/10.1038/s41467-019-10189-x.
Henagan, T.M., Cefalu, W.T., Ribnicky, D.M., Noland, R.C., Dunville, K.,
Campbell, W.W., Stewart, L.K., Forney, L.A., Gettys, T.W., Chang, J.S. &
Morrison, C.D. 2015. In vivo effects of dietary quercetin and quercetin-rich
red onion extract on skeletal muscle mitochondria, metabolism, and insulin
sensitivity. Genes and Nutrition, 10(1).
Hotamisligil, G.S. 2000. Molecular mechanisms of insulin resistance and the role
of the adipocyte. International Journal of Obesity, 24: S23–S27.
Hong, S.H., Heo, J., Kim, J., Kwon, S. & Yeo, K. 2013. Antidiabetic and Beta
Cell-Protection Activities of Purple Corn. Biomol Ther, 21(4): 284–289.
Honma, M., Sawada, S., Ueno, Y., Murakami, K., Yamada, T., Gao, J., Kodama,
S., Izumi, T., Takahashi, K., Tsukita, S., Uno, K., Imai, J., Kakazu, E.,
Kondo, Y., Mizuno, K., Kawagishi, N., Shimosegawa, T. & Katagiri, H.
2018. Selective insulin resistance with differential expressions of IRS-1 and
IRS-2 in human NAFLD livers. International Journal of Obesity, 42(9):
1544–1555. http://dx.doi.org/10.1038/s41366-018-0062-9.
Horst, K.W. & Serlie, M.J. 2017. Fructose consumption, lipogenesis, and non-
alcoholic fatty liver disease. Nutrients, 9(9): 1–20.
Hsu, M.C., Wang, M.E., Jiang, Y.F., Liu, H.C., Chen, Y.C. & Chiu, C.H. 2017.
Long-term feeding of high-fat plus high-fructose diet induces isolated
impaired glucose tolerance and skeletal muscle insulin resistance in
miniature pigs. Diabetology and Metabolic Syndrome, 9(1): 1–12.
Ighodaro, O.M. 2018. Molecular pathways associated with oxidative stress in
diabetes mellitus. Biomedicine and Pharmacotherapy, 108(August): 656–
662. https://doi.org/10.1016/j.biopha.2018.09.058.
Ipsen, D.H., Lykkesfeldt, J. & Tveden-Nyborg, P. 2018. Molecular mechanisms
of hepatic lipid accumulation in non-alcoholic fatty liver disease. Cellular
and Molecular Life Sciences, 75(18): 3313–3327.
https://doi.org/10.1007/s00018-018-2860-6.
Irimia, J.M., Meyer, C.M., Segvich, D.M., Surendran, S., Depaoli-Roach, A.A.,
Morral, N. & Roach, P.J. 2017. Lack of liver glycogen causes hepatic
insulin resistance and steatosis in mice. Journal of Biological Chemistry,
292(25): 10455–10464.
Iqbal, U., Perumpail, B., Akhtar, D., Kim, D. & Ahmed, A. 2019. The
Epidemiology, Risk Profiling and Diagnostic Challenges of Nonalcoholic
Fatty Liver Disease. Medicines, 6(1): 41.
Jamaluddin, M.S., Weakley, S.M., Yao, Q. & Chen, C. 2012. Resistin: Functional
roles and therapeutic considerations for cardiovascular disease. British
Journal of Pharmacology, 165(3): 622–632.
Janus, A., Mazur, G. & Doroszko, A. 2016. Insulin Resistance and Endothelial
Dysfunction Constitute a Common Therapeutic Target in Cardiometabolic
Disorders. Mediators of Inflammation.
http://dx.doi.org/10.1155/2016/3634948.
Jensen, T., Abdelmalek, M.F., Sullivan, S., Nadeau, K.J., Green, M., Roncal, C.,
Nakagawa, T., Kuwabara, M., Sato, Y., Kang, D.H., Tolan, D.R., Sanchez-
Lozada, L.G., Rosen, H.R., Lanaspa, M.A., Diehl, A.M. & Johnson, R.J.
2018. Fructose and sugar: A major mediator of non-alcoholic fatty liver
disease. Journal of Hepatology, 68(5): 1063–1075.
Jin, E.S., Browning, J.D., Murphy, R.E. & Malloy, C.R. 2018. Fatty liver disrupts
glycerol metabolism in gluconeogenic and lipogenic pathways in humans.
Journal of Lipid Research, 59(9): 1685–1694.
Ježek, J., Cooper, K.F. & Strich, R. 2018. Reactive oxygen species and
mitochondrial dynamics: The yin and yang of mitochondrial dysfunction
and cancer progression. Antioxidants, 7(1).
Kalea, A.Z., Schmidt, A.M. & Hudson, B.I. 2009. RAGE: A novel biological and
genetic marker for vascular disease. Clinical Science, 116(8): 621–637.
Keskin, M., Kurtoglu, S., Kendirci, M. & Atabek, M.E. 2005. Homeostasis Model
Assessment Is More Reliable Than the Fasting Glucose / Insulin Ratio and
Quantitative Insulin Sensitivity Check Index for Assessing Insulin
Resistance Among Obese Children and Adolescents. Pediatrics, 115(4):
500–503.
Khan, R.S., Bril, F., Cusi, K. & Newsome, P.N. 2019. Modulation of Insulin
Resistance in Nonalcoholic Fatty Liver Disease. Hepatology, 70(2).
Khitan, Z. & Kim, D.H. 2013. Fructose: A key factor in the development of
metabolic syndrome and hypertension. Journal of Nutrition and
Metabolism, 2013.
Khoo, H.E., Azlan, A., Tang, S.T. & Lim, S.M. 2017. Anthocyanidins and
anthocyanins: colored pigments as food, pharmaceutical ingredients, and the
potential health benefits. Food & Nutrition Research, 61(1): 1361779.
https://doi.org/10.1080/16546628.2017.1361779.
Kim, D., Touros, A. & Kim, W.R. 2017. Nonalcoholic Fatty Liver Diseases and
Metabolic Syndrome. Clinical Liver Diseases.
http://dx.doi.org/10.1016/j.cld.2017.08.010.
Kim, H.Y., Choi, J.Y. & Park, Y. 2019. Relative skeletal muscle mass and non-
alcoholic fatty liver disease : from association to causation. Hepato Biliary
Surg Nutr , 8(7): 509–511. http://dx.doi.org/10.21037/hbsn.2019.04.13.
Konstantynowicz-Nowicka, Berk, Chabowski, Kasacka, Bielawiec, Łukaszuk &
Harasim-Symbor. 2019. High-Fat Feeding in Time-Dependent Manner
Affects Metabolic Routes Leading to Nervonic Acid Synthesis in NAFLD.
International Journal of Molecular Sciences, 20(15): 3829.
Koren S, Fantus IG. 2007. Inhibition of the protein tyrosine phosphatase PTP1B:
potential therapy for obesity, insulin resistance and type-2 diabetes mellitus.
Best Pract Res Clin Endocrinol Metab, 21:621–64
Kubota, N., Kubota, T., Itoh, S., Kumagai, H., Kozono, H., Takamoto, I.,
Mineyama, T., Ogata, H., Tokuyama, K., Ohsugi, M., Sasako, T., Moroi,
M., Sugi, K., Kakuta, S., Iwakura, Y., Noda, T., Ohnishi, S., Nagai, R.,
Tobe, K., Terauchi, Y., Ueki, K. & Kadowaki, T. 2008. Dynamic Functional
Relay between Insulin Receptor Substrate 1 and 2 in Hepatic Insulin
Signaling during Fasting and Feeding. Cell Metabolism, 8(1): 49–64.
Kurutas, E.B. 2016. The importance of antioxidants which play the role in cellular
response against oxidative / nitrosative stress : current state. Nutrition
Journal: 1–22. http://dx.doi.org/10.1186/s12937-016-0186-5.
Lan, Y., Lou, J., Lyu, W. & Zhang, B. 2019. Review: update on the synergistic
effect of HSL
and insulin in the treatment of metabolic disorders. Therapeutic Advances in
Endocrinology and Metabolism,10(10):1-10.
Lanywati E., 2007. Diabetes Mellitus Penyakit Kencing Manis. Kanisius
Yogyakarta, Yogyakarta.
Lawrence, T. & Natoli, G. 2011. Transcriptional regulation of macrophage
polarization : enabling diversity with identity. Nature Reviews Immunology,
11(11): 750–761. http://dx.doi.org/10.1038/nri3088.
Lazar, M. (2007). Resistin- and Obesity-associated Metabolic Diseases. Hormone
and Metabolic Research, 39(10), 710–716. doi:10.1055/s-2007-985897
Lee, S., Lee, H.C., Kwon, Y.W., Lee, S.E., Cho, Y., Kim, J., Lee, S., Kim, J.Y.,
Lee, J., Yang, H.M., Mook-Jung, I., Nam, K.Y., Chung, J., Lazar, M.A. &
Kim, H.S. 2014. Adenylyl cyclase-associated protein 1 is a receptor for
human resistin and mediates inflammatory actions of human monocytes.
Cell Metabolism, 19(3): 484–497.
http://dx.doi.org/10.1016/j.cmet.2014.01.013.
Li, S., Amo-aparicio, J., Neff, C.P., Tengesdal, I.W., Azam, T. & Palmer, B.E.
2019. Role for nuclear interleukin-37 in the suppression of innate immunity.
PNAS, 116(10).
Li, S., Xu, R.X., Zhang, Y., Guo, Y.L., Zhu, C.G., Liu, G., Dong, Q. & Li, J.J.
2015. Relation of resistin to proprotein convertase subtilisin-kexin type 9
levels in coronary artery disease patients with different nutritional status.
Journal of Endocrinological Investigation, 38(12): 1291–1299.
Li S, Hong M, Tan HY, Wang N, Feng Y. 2016. Insights into the Role and
Interdependence of Oxidative Stress and Inflammation in Liver Diseases.
Oxid Med Cell Longev, 2016:4234061.
Lingappan, K. 2018. NF-κB in oxidative stress. Current Opinion in Toxicology, 7:
81–86.
Lonardo, A., Sookoian, S., Pirola, C.J. & Targher, G. 2016. Non-alcoholic fatty
liver disease and risk of cardiovascular disease. Metabolism: Clinical and
Experimental, 65(8): 1136–1150.
http://dx.doi.org/10.1016/j.metabol.2015.09.017.
Luo, Z., Zhang, Y., Li, F., He, J., Ding, H., Yan, L., & Cheng, H. 2009. Resistin
induces insulin resistance by both AMPK-dependent and AMPK-
independent mechanisms in HepG2 cells. Endocrine, 36(1), 60–69.
doi:10.1007/s12020-009-9198-7
Malherbe, P., Richards, J.G., Gaillard, H., Thompson, A., Diener, C., Schuler, A.
& Huber, G. 1999. cDNA cloning of a novel secreted isoform of the human
receptor for advanced glycation end products and characterization of cells
co-expressing cell-surface scavenger receptors and Swedish mutant amyloid
precursor protein. Molecular Brain Research, 71(2): 159–170.
Mansouri, A., Gattolliat, C.H. & Asselah, T. 2018. Mitochondrial Dysfunction
and Signaling in Chronic Liver Diseases. Gastroenterology, 155(3): 629–
647. https://doi.org/10.1053/j.gastro.2018.06.083.
Mantovani, A., Byrne, C.D. & Bonora, E. 2018. Nonalcoholic Fatty Liver Disease
and Risk of Incident Type 2 Diabetes : A Meta-analysis. Diabetes Care, 41:
372–382.
Marchesini, G., Bugianesi, E., Forlani, G., Cerrelli, F., Lenzi, M., Manini, R.,
Natale, S., Vanni, E., Villanova, N., Melchionda, N. & Rizzetto, M.
Nonalcoholic Fatty Liver, Steatohepatitis, and the Metabolic Syndrome.
Hepatology, 37(4): 917–923.
Masarone, M., Rosato, V., Dallio, M., Gravina, A.G., Aglitti, A., Loguercio, C.,
Federico, A. & Persico, M. 2018. Role of Oxidative Stress in
Pathophysiology of Nonalcoholic Fatty Liver Disease. Oxidative medicine
and cellular longevity, 2018: 9547613.
Matafome P, Rodrigues T, Sena C, Seiça R. 2016. Methylglyoxal in Metabolic
Disorders: Facts, Myths, and Promises. Med Res Rev, 37:368–403.
Mataram City Health Department. 2015. Health Profile of the City of Mataram in
2014. Ministry of Health of the Republic of Indonesia.
Mathebula, S.D. 2015. Polyol pathway: A possible mechanism of diabetes
complications in the eye. African Vision and Eye Health, 74(1): 1–5.
Matsui T., Ebuchi S., Kobayashi M., Fukui K., Sugita K., Terahara N., et al. .
(2002). Anti-hyperglycemic effect of diacylated anthocyanin derived from
Ipomoea batatas cultivar Ayamurasaki can be achieved through the α-
glucosidase inhibitory action. J. Agric. Food Chem. 50, 7244–7248.
10.1021/jf025913m
Meex, R.C.R. & Watt, M.J. 2017. Hepatokines : linking nonalcoholic fatty liver
disease and insulin resistance. Nature Publishing Group, 13(9): 509–520.
http://dx.doi.org/10.1038/nrendo.2017.56.
Matafome P, Rodrigues T, Sena C, Seiça R. Methylglyoxal in Metabolic
Disorders:
Facts, Myths, and Promises. Med Res Rev 2016;37:368–403.
Melone, M., Wilsie, L., Palyha, O., Strack, A. & Rashid, S. 2012. Discovery of a
new role of human resistin in hepatocyte low-density lipoprotein receptor
suppression mediated in part by proprotein convertase subtilisin/kexin type
9. Journal of the American College of Cardiology, 59(19): 1697–1705.
http://dx.doi.org/10.1016/j.jacc.2011.11.064.
Messier, C., Desrochers, A. & Gagnon, M. 1999. Effect of glucose, glucose
regulation, and word imagery value on human memory. Behavioral
Neuroscience, 113(3): 431–438.
Mien K. Mahmud M.S., Hermana, Nils Aria Zulfianto. Rossi Rozanna,
Apriyantoro, Iskari Ngadiarti, Budi Hartati, Bernadus, Tinexcelly. 2009.
Tabel komposisi pangan Indonesia. Persatuan Ahli Gizi Indonesia. PT Elex
Media Komputindo: 10.
Mirshekar M., Roghani M., Khalili M., Baluchnejadmojarad T., Moazzen S. A.
(2010). Chronic oral pelargonidin alleviates streptozotocin-induced diabetic
neuropathic hyperalgesia in rat: involvement of oxidative stress. Iran.
Biomed. J. 14, 33–39.
Moghaddasifar, I., Lankarani, K.B., Moosazadeh, M., Afshari, M., Ghaemi, A.,
Aliramezany, M., Gharebagh, R.A. & Malary, M. 2016. Prevalence of Non-
alcoholic Fatty Liver Disease and Its Related Factors in Iran: Systematic
Review. Int J Org Transplant Med, 7(3):150-160.
Morelli, A.M., Ravera, S., Calzia, D. & Panfoli, I. 2019. An update of the
chemiosmotic theory as suggested by possible proton currents inside the
coupling membrane. Open Biology, 9(4).
Mortera, R.R., Bains, Y., & Gugliucci, A. 2019. Fructose at the crossroads of the
metabolic syndrome and obesity epidemics. Frontiers In Bioscience,
Landmark, 24: 186-211.
Nandipati, K.C., Subramanian, S. & Agrawal, D.K. 2017. Protein kinases:
mechanisms and downstream targets in inflammation-mediated obesity and
insulin resistance. Molecular and Cellular Biochemistry, 426(1–2): 27–45.
Neuschwander-tetri, B.A. 2017. Non-alcoholic fatty liver disease:Minireview.
BMC Medicine 15(45): 1–6. DOI 10.1186/s12916-017-0806-8
Nier, A., Engstler, A.J., Maier, I.B. & Bergheim, I. 2017. Markers of intestinal
permeability are already altered in early stages of non-alcoholic fatty liver
disease: Studies in children. PLoS ONE, 12(9): 1–12.
Ning, B., Wang, X., Yu, Y., Waqar, A.B., Yu, Q., Koike, T., Shiomi, M., Liu, E.,
Wang, Y. & Fan, J. 2015. High-fructose and high-fat diet-induced insulin
resistance enhances atherosclerosis in Watanabe heritable hyperlipidemic
rabbits. Nutrition and Metabolism, 12(1): 1–11.
Nolan, C.J. & Prentki, M. 2019. Insulin resistance and insulin hypersecretion in
the metabolic syndrome and type 2 diabetes: Time for a conceptual
framework shift. Diabetes and Vascular Disease Research, 16(2): 118–127.
Olefsky, J.M. & Saekow, M. 1978. The Effects of Dietary Carbohydrate Content
on Insulin Binding and Glucose Metabolism by Isolated Rat Adipocytes.
Endocrinology, 103(6): 2252–2263.
Ormazabal, V., Nair, S., Elfeky, O., Aguayo, C., Salomon, C. & Zuñiga, F.A.
2018. Association between insulin resistance and the development of
cardiovascular disease. Cardiovascular Diabetology: 17–122.
https://doi.org/10.1186/s12933-018-0762-4.
Ore, A. & Akinloye, O.A. 2019. Oxidative Stress and Antioxidant Biomarkers in
Clinical and Experimental Models of Non-Alcoholic Fatty Liver Disease.
Medicina (Kaunas, Lithuania), 55(2)
Ott, C., Jacobs, K., Haucke, E., Navarrete Santos, A., Grune, T. & Simm, A.
2014. Role of advanced glycation end products in cellular signaling. Redox
Biology, 2(1): 411–429. http://dx.doi.org/10.1016/j.redox.2013.12.016.
Palma-Duran, S.A., Kontogianni, M.D., Vlassopoulos, A., Zhao, S., Margariti, A.,
Georgoulis, M., Papatheodoridis, G. & Combet, E. 2018. Serum levels of
advanced glycation end-products (AGEs) and the decoy soluble receptor for
AGEs (sRAGE) can identify non-alcoholic fatty liver disease in age-, sex-
and BMI-matched normo-glycemic adults. Metabolism: Clinical and
Experimental, 83: 120–127.
Pan, M. H., Lai, C. S., Tsai, M. L., Ho, C. T. 2014. Chemoprevention of
nonalcoholic fatty liver disease by dietary natural compounds. Mol Nutr
Food Res, 58:147–71.
Panchal, S.K., Poudyal, H., Iyer, A., Nazer, R., Alam, A., Diwan, V., Kauter, K.,
Sernia, C., Campbell, F., Ward, L., Gobe, G., Fenning, A. & Brown, L.
2011. High-carbohydrate high-fat diet-induced metabolic syndrome and
cardiovascular remodeling in rats. Journal of Cardiovascular
Pharmacology, 57(1): 51–64.
Park, H.K., Kwak, M.K., Kim, H.J. & Ahima, R.S. 2017. Linking resistin,
inflammation, and cardiometabolic diseases. Korean Journal of Internal
Medicine, 32(2): 239–247.
Patel, L., Buckels, A. C., Kinghorn, I. J., Murdock, P. R., Holbrook, J. D.,
Plumpton, C., Smith, S. A. (2003). Resistin is expressed in human
macrophages and directly regulated by PPARγ activators. Biochemical and
Biophysical Research Communications, 300(2), 472–476.
doi:10.1016/s0006-291x(02)02841-3.
Pathak, V., Pathak, N.M., O’Neill, C.L., Guduric-Fuchs, J. & Medina, R.J. 2019.
Therapies for Type 1 Diabetes: Current Scenario and Future Perspectives.
Clinical Medicine Insights: Endocrinology and Diabetes, 12.
Pereira, R.M., Botezelli, J.D., da Cruz Rodrigues, K.C., Mekary, R.A., Cintra,
D.E., Pauli, J.R., da Silva, A.S.R., Ropelle, E.R. & de Moura, L.P. 2017.
Fructose consumption in the development of obesity and the effects of
different protocols of physical exercise on the hepatic metabolism.
Nutrients, 9(4): 1–21.
Perla, F., Prelati, M., Lavorato, M., Visicchio, D. & Anania, C. 2017. The Role of
Lipid and Lipoprotein Metabolism in Non‐Alcoholic Fatty Liver Disease.
Children, 4(6): 46.
Perkeni, 2006. Konsensus Pengelolaan DM di Indodesia. Jakarta : PERKENI.
Philips P.B (1999). Collaborative Effort In Rural North Carolina Country
Produces.
Patterson, R.E., Kalavalapalli, S., Williams, C.M., Nautiyal, M., Mathew, J.T.,
Martinez, J., Reinhard, M.K., McDougall, D.J., Rocca, J.R., Yost, R.A.,
Cusi, K., Garrett, T.J. & Sunny, N.E. 2016. Lipotoxicity in steatohepatitis
occurs despite an increase in tricarboxylic acid cycle activity. American
Journal of Physiology - Endocrinology and Metabolism, 310(7): E484–
E494.
Plows, J.F., Stanley, J.L., Baker, P.N., Reynolds, C.M. & Vickers, M.H. 2018.
The Pathophysiology of Gestational Diabetes Mellitus. International
Renna LV, Bosè F, Iachettini S, Fossati B, Saraceno L, Milani V, et al. (2017)
Receptor and post-receptor abnormalities contribute to insulin resistance in
myotonic dystrophy type 1 and type 2 skeletal muscle. PLoS ONE 12(9):
e0184987.
https://doi.org/10.1371/journal.pone.0184987
Rojas, J., Bermudez, V., Palmar, J., Martínez, M.S., Olivar, L.C., Nava, M.,
Tomey, D., Rojas, M., Salazar, J., Garicano, C. & Velasco, M. 2018.
Pancreatic beta cell death: Novel potential mechanisms in diabetes therapy.
Journal of Diabetes Research, 2018(Dm).
Rutledge, A.C. & Adeli, K. 2007. Fructose and the Metabolic Syndrome :
Pathophysiology and Molecular Mechanisms Involvement Of Fructose, A
Lipogenic Nutrient , In Initiation Of The. Nutrition, 65(6): 13–23.
Salamone, F., Bugianesi, E., Pietka, T., Na, A., Bw, P., Okunade, A. & Proc, K.S.
2010. International Hepatology Nonalcoholic fatty liver disease : The
hepatic trigger of the metabolic syndrome. Journal of Hepatology, 53(6):
1146–1147.
http://dx.doi.org/10.1016/j.jhep.2010.06.013.
Saltiel, A.R. & Kahn, C.R. 2001. Insulin signalling and the regulation of glucose
and lipid metabolism. Nature, 414(6865): 799–806.
Samuel, V.T. 2011. Fructose induced lipogenesis: From sugar to fat to insulin
resistance. Trends in Endocrinology and Metabolism, 22(2): 60–65.
http://dx.doi.org/10.1016/j.tem.2010.10.003.
Santos, J.C. de F., Valentim, I.B., de Araújo, O.R.P., Ataide, T. da R. & Goulart,
M.O.F. 2013. Development of nonalcoholic hepatopathy: Contributions of
oxidative stress and advanced glycation end products. International Journal
of Molecular Sciences, 14(10): 19846–19866.
Satoh, H., Nguyen, M.T.A., Miles, P.D.G., Imamura, T., Usui, I. & Olefsky, J.M.
2004. Adenovirus-mediated chronic ‘hyper-resistinemia’ leads to in vivo
insulin resistance in normal rats. Journal of Clinical Investigation, 114(2):
224–231.
Schwartz, D.R., Briggs, E.R., Qatanani, M., Sawaya, H., Sebag, I.A., Picard,
M.H., Scherrer-Crosbie, M. & Lazar, M.A. 2013. Human resistin in
chemotherapy-induced heart failure in humanized male mice and in women
treated for breast cancer. Endocrinology, 154(11): 4206–4214.
Shimomura, I., Matsuda, M., Hammer, R.E., Bashmakov, Y., Brown, M.S. &
Goldstein, J.L. 2000. Decreased IRS-2 and increased SREBP-1c lead to
mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob
mice. Molecular Cell, 6(1): 77–86.
Shoelson, S.E., Lee, J. & Goldfine, A.B. 2006. Review series Inflammation and
insulin resistance. Diabetes, 116(7): 1793–1801.
Softic, S., Cohen, D. E., Kahn, C. R. 2016. Role of dietary fructose and hepatic de
novo lipogenesis in fatty liver disease. Dig Dis Sci, 61:1282–1293.
Song, R., Wang, X., Mao, Y., Li, H., Li, Z., Xu, W. & Wang, R. 2013. Resistin
disrupts glycogen synthesis under high insulin and high glucose levels by
Song, H.M., Li, X., Liu, Y.Y., Lu, W.P., Cui, Z.H., Zhou, L., Yao, D. &
Zhang, H.M. 2018. Carnosic acid protects mice from high-fat diet-induced
NAFLD by regulating MARCKS. International Journal of Molecular
Medicine, 42(1): 193–207.down-regulating the hepatic levels of GSK3beta.
Gene 529:50-56.
Stanhope, K.L., Schwarz, J.M., Keim, N.L., Griffen, S.C., Bremer, A.A., Graham,
J.L., Hatcher, B., Cox, C.L., Dyachenko, A., Zhang, W., Mcgahan, J.P.,
Seibert, A., Krauss, R.M. & Chiu, S. 2009. Consuming fructose-sweetened,
not glucose- sweetened, beverages increases visceral adiposity and lipids
and decreases insulin sensitivity in overweight/obese humans. The Journal
of Clinical Investigation, 1334(5): 1322–1334.
Steppan, CM. Bailey, ST. Bhat, S. Brown, EJ. Banerjee, RR. Wright, C. Patel,
HR. Ahima, RS. Lazar. 2001. The hormone resistin links obesity to
diabetes. Nature, 409:307-312.
Sumiyoshi, M., Sakanaka, M. & Kimura, Y. 2006. Chronic Intake of High-Fat
and High-Sucrose Diets Differentially Affects Glucose Intolerance in Mice.
The Journal of Nutrition, 136(3): 582–587.
Sun, S.Z. & Empie, M.W. 2013. Fructose metabolism in humans: What isotopic
tracer studies tell us. Functional Foods: The Connection Between Nutrition,
Health, and Food Science: 109–143.
Szendroedi, J., Yoshimura, T., Phielix, E., Koliaki, C., Marcucci, M., Zhang, D.,
Jelenik, T., Müller, J., Herder, C., Nowotny, P., Shulman, G.I. & Roden, M.
2014. Role of diacylglycerol activation of PKCθ in lipid-induced muscle
insulin resistance in humans. Proceedings of the National Academy of
Sciences of the United States of America, 111(26): 9597–9602.
Tabata, S., Yoshimitsu, S., Hamachi, T., Abe, H., Ohnaka, K. & Kono, S. 2009.
Waist circumference and insulin resistance: a cross-sectional study of
Japanese men. BMC Endocrine Disorders, 9(1): 1–7.
Tang, W.H., Martin, K.A. & Hwa, J. 2012. Aldose reductase, oxidative stress, and
diabetic mellitus. Frontiers in Pharmacology, 3: 1–8.
Taghizadeh, E., Mardani, R., Rostami, D., Taghizadeh, H., Bazireh, H. & Hayat,
S.M.G. 2019. Molecular mechanisms, prevalence, and molecular methods
for familial combined hyperlipidemia disease: A review. Journal of
Cellular Biochemistry, 120(6): 8891–8898.
Tana, C., Ballestri, S., Ricci, F., Di Vincenzo, A., Ticinesi, A., Gallina, S.,
Giamberardino, M.A., Cipollone, F., Sutton, R., Vettor, R., Fedorowski, A.
& Meschi, T. 2019. Cardiovascular Risk in Non-Alcoholic Fatty Liver
Disease: Mechanisms and Therapeutic Implications. International Journal
of Environmental Research and Public Health, 16(17): 3104.
Tarkowski, A., Bjersing, J., Shestakov, A. & Bokarewa, M.I. 2010. Resistin
competes with lipopolysaccharide for binding to toll-like receptor 4. J. Cell.
Mol. Med, 14(6): 1419–1431.
Tappy, L. 2018. Fructose-containing caloric sweeteners as a cause of obesity and
metabolic disorders. Journal of Experimental Biology, 121.
Taskinen, M., Packard, C.J., and Boren, J. 2019. Dietary fructose and the
metabolic syndrome. Current Opinion in Gastroenterology, 24(2): 204–209.
Teff, K.L., Grudziak, J., Townsend, R.R., Dunn, T.N., Grant, R.W., Adams, S.H.,
Keim, N.L., Cummings, B.P., Stanhope, K.L. & Havel, P.J. 2009. Fructose-
and Glucose-Sweetened Beverages with Meals in Obese Men and Women :
Influence of Insulin. J Clin Endocrinol Metab, 94(5): 1562–1569.
Ter Horst, K.W. & Serlie, M.J. 2017. Fructose consumption, lipogenesis, and non-
alcoholic fatty liver disease. Nutrients, 9(9): 1–20.
Thomsen, S.K. & Gloyn, A.L. 2014. The pancreatic β cell: Recent insights from
human genetics. Trends in Endocrinology and Metabolism, 25(8): 425–434.
http://dx.doi.org/10.1016/j.tem.2014.05.001.
Tranchida, F., Tchiakpe, L., Rakotoniaina, Z., Deyris, V., Ravion, O. & Hiol, A.
2012. Long-term high fructose and saturated fat diet affects plasma fatty
acid profile in rats. Journal of Zhejiang University: Science B, 13(4): 307–
317.
Tricò, D., Mari, A., Ferrannini, E., Tricò, D., Natali, A., Arslanian, S., Mari, A. &
Ferrannini, E. 2018. Implications of Primary Insulin Hypersecretion in
Nondiabetic Adults and Adolescents. JCI Insight, 3(24): 1–15.
Tsukita, S., Yamada, T., Uno, K., Takahashi, K., Kaneko, K., Ishigaki, Y., Imai,
J., Hasegawa, Y., Sawada, S., Ishihara, H., Oka, Y. & Katagiri, H. 2012.
Hepatic glucokinase modulates obesity predisposition by regulating BAT
thermogenesis via neural signals. Cell Metabolism, 16(6): 825–832.
http://dx.doi.org/10.1016/j.cmet.2012.11.006.
United States Departement of Agriculture (USDA). Cajanus cajan. Natural
Resource Conservation Service. https://plants.usda.gov/java/Classification .
Diakses September 2019.
USDA National Nutrient data base. Pigeonpeas (Cajanus cajun), Raw, mature
seeds, Nutritive value per 100 g. Diakses September 2019.
Utzschneider, K.M. & Kahn, S.E. 2006. REVIEW : The Role of Insulin
Resistance in Nonalcoholic Fatty Liver Disease. The Journal of Clinical
Endocrinology & Metabolism, 91(12): 4753–4761.
Van De Wier, B., Koek, G.H., Bast, A. & Haenen, G.R.M.M. 2017. The potential
of flavonoids in the treatment of non-alcoholic fatty liver disease. Critical
Reviews in Food Science and Nutrition, 57(4): 834–855.
http://dx.doi.org/10.1080/10408398.2014.952399.
Vinogradov, A.D. & Grivennikova, V.G. 2016. Oxidation of NADH and ROS
production by respiratory complex i. Biochimica et Biophysica Acta -
Bioenergetics, 1857(7): 863–871.
http://dx.doi.org/10.1016/j.bbabio.2015.11.004.
Volpe, C.M.O., Villar-Delfino, P.H., Dos Anjos, P.M.F. & Nogueira-Machado,
J.A. 2018. Cellular death, reactive oxygen species (ROS) and diabetic
complications review-Article. Cell Death and Disease, 9(2).
Von Frankenberg, A.D., Marina, A., Song, X., Callahan, H.S., Kratz, M. &
Utzschneider, K.M. 2017. A high-fat, high-saturated fat diet decreases
insulin sensitivity without changing intra-abdominal fat in weight-stable
overweight and obese adults. European Journal of Nutrition, 56(1): 431–
443.
Wiebke, A.B., Viktoria, B. & Manfred, A. 2018. Determinants of ectopic liver fat
in metabolic disease. European Journal of Clinical Nutrition.
http://dx.doi.org/10.1038/s41430-018-0323-7.
Wilcox, G. 2005. Insulin and Insulin Resistance. Clin Biochem Rev, 26: 19–39.
Wild S., Gojka R., Adreas G., Richard S., Hilary K., 2004. Global Prevalence Of
Diabetes Estimate for The Year 2000 and Projections for 2030. Diabetes
Care, 27(5):1047-105.
Win,S., Than, T.A., Zhang, J., Christina, Min, R.W.M., & Kaplowitz, N. 2018.
New insights into the role and mechanism of c-Jun-N-terminal kinase
signaling in the pathobiology of liver diseases. Hepatology, 67(5): 2013–
2024. doi:10.1002/hep.29689
Wong, W. & Brown, L. 2014. Diabetic Cardiomyopathy: Biochemical and
Molecular Mechanisms. Diabetic Cardiomyopathy: Biochemical and
Molecular Mechanisms: 41-63.
World Health Organization. Obesity and Overweight. https://www.who.int/news-
room/fact-sheets/detail/obesity-and-overweight. Diakses September 2019.
Wu, J., Jin, Z., Zheng, H. & Yan, L.J. 2016. Sources and implications of
NADH/NAD+ redox imbalance in diabetes and its complications. Diabetes,
Metabolic Syndrome and Obesity: Targets and Therapy, 9: 145–153.
Xiao, Y., Wang, J., Yan, W., Zhou, K., Cao, Y. & Cai, W. 2017. P38α MAPK
antagonizing JNK to control the hepatic fat accumulation in pediatric
patients onset intestinal failure. Cell Death and Disease, 8(10): 1–11.
Xu, H., Li, X., Adams, H., Kubena, K. & Guo, S. 2019. Etiology of metabolic
syndrome and dietary intervention. International Journal of Molecular
Sciences, 20(1): 1–19.
Yamamoto, Y., Kato, I., Doi, T., Yonekura, H. & Ohashi, S. 2001. Development
and prevention of advanced diabetic nephropathy in RAGE-overexpressing
mice Find the latest version : Development and prevention of advanced
diabetic. J Clin Invest, 108(2):261-268.
Yan F., Dai G., Zheng X. 2016. Mulberry anthocyanin extract ameliorates insulin
resistance by regulating PI3K/AKT pathway in HepG2 cells and db/db
mice. J. Nutr. Biochem. 36, 68–80. 10.1016/j.jnutbio.2016.07.004
Yan, H., Gao, Y. & Zhang, Y. 2017. Inhibition of JNK suppresses autophagy and
attenuates insulin resistance in a rat model of nonalcoholic fatty liver
disease. Molecular Medicine Reports, 15(1): 180–186.
Yang, X., Zhao, Y., Sun, Q., Yang, Y., Gao, Y., Ge, W., Liu, J., Xu, X. & Zhang,
J. 2019. An Intermediary Role of Adenine Nucleotides on Free Fatty Acids-
Induced Hyperglycemia in Obese Mice. Frontiers in Endocrinology,
10(August): 1–9.
Yki-järvinen, H. 2014. Non-alcoholic fatty liver disease as a cause and a
consequence of metabolic syndrome. Lancet Diabetes Endocrinol, 2: 901–
910.
Younossi, Z., Anstee, Q.M., Marietti, M., Hardy, T., Henry, L., Eslam, M.,
George, J. & Bugianesi, E. 2018. Global burden of NAFLD and NASH:
Trends, predictions, risk factors and prevention. Nature Reviews
Gastroenterology and Hepatology, 15(1): 11–20.
http://dx.doi.org/10.1038/nrgastro.2017.109.