GENERIC NAME: DOSAGE/ SIDE EFFECTS/ NURSING

Insulin lispro FREQUENCY/ ROUTE: ADVERSE REACTION RESPONSIBILITIES

Subcutaneous Injection:
Humalog U-100 or U-
200
BRAND NAME: INDICATION: More common  Ensure uniform
Humalog  Type 1 diabetes dispersion of insulin
 Type 2 diabetes  Anxious or suspensions by
 Insulin Resistance nervous feeling rolling the vial
DRUG ILLUSTRATION:  DKA  behavior change gently between
 Gestational diabetes similar to being hands; avoid
drunk vigorous shaking.
 blurred vision  Give maintenance
 chills doses
 cold sweats subcutaneously,
 confusion or rotating injection
difficulty thinking sites regularly to
CLASSIFICATION: CONTRAINDICATION: decrease incidence
 depression
Insulins of lipodystrophy;
 dizziness or
 during lightheadedness
give regular insulin
IV or IM in severe
episodes of  drowsiness
MECHANISM OF ketoacidosis or
hypoglycemia  excessive hunger diabetic coma.
ACTION: 
Insulin is a hormone  in patients fast heartbeat  Obtain baseline and
who are  fever periodic PFTs for
secreted by the pancreas. It
 headache patient using
regulates the movement of hypersensitive
glucose from blood into  irritability or inhaled insulin;
to Humalog or abnormal behavior carefully monitor
cells. Insulin lowers blood
glucose by stimulating to any of its  lower back or side glucose levels when
peripheral glucose uptake excipients. pain converting from
primarily by skeletal  nightmares subcutaneous to
muscle cells and fat, and by  painful or difficult inhaled insulin
inhibiting glucose urination  Monitor patients
production and release by  restless sleep receiving insulin IV
the liver. Insulin inhibits  seizures carefully; plastic IV
lipolysis (breakdown of  shakiness infusion sets have
fat), proteolysis  slurred speech been reported to
(breakdown of proteins), remove 20%–80%
 tingling in the
and gluconeogenesis of the insulin;
hands, feet, lips, or
(manufacture of glucose). It dosage delivered to
tongue
also increases protein the patient will
synthesis and conversion of vary.
Less common
excess glucose into fat.  Do not give insulin
Insulins used to treat injection
 Dry, red, hot, or
diabetes are concentrated IV;
irritated skin
pharmacologically similar severe anaphylactic
to the naturally produced reactions can occur.
hormone. Patients with Rare  Use the same type
diabetes are insensitive to and brand of
insulin and do not produce  Depression of the syringe; use the
enough insulin which leads skin at the same type and brand
to hyperglycemia and injection site of insulin to avoid
symptoms of diabetes.  dryness of the dosage errors.
Exogenous insulin mouth Arrange for proper
preparations replace insulin  fast or weak pulse disposal of syringes.
in diabetics, increasing the  itching, redness, or  Do not change the
uptake of glucose by cells swelling at the order of mixing
and reducing the short and injection site insulins. Rotate
long term consequences of  muscle cramps or injection sites
diabetes. pain regularly (keep a
 nausea chart of sites used)
to prevent
 skin rash or
breakdown at
itching over the
injection sites.
whole body
 sweating
 thickening of the
skin at the
injection site
 trouble breathing
 unusual tiredness
or weakness
 vomiting

REFERENCES

https://www.diabetesdaily.com/learn-about-diabetes/treatment/types-of-insulin/faster-acting-
insulins/humalog-lispro/

https://my.clevelandclinic.org/health/drugs/13902-injectable-insulin-medications

https://www.drugs.com/pro/humalog.html

https://www.medicinenet.com/insulin_for_diabetes_treatment_types_side_effects/article.htm#how_w
ell_does_insulin_treat_diabetes

https://www.drugs.com/sfx/insulin-lispro-side-effects.html

https://www.rnpedia.com/nursing-notes/pharmacology-drug-study-notes/insulin/