Abstract Book of ICICS 2018 Papua-2

Interna(onal Conference of The Indonesian Chemical Society

2
PREFACE
On behalf of the conference organizing commi2ee, we are happy to pre-

sent the Book of Abstract of the Seventh Indonesian Conference of the Indonesian
Chemical Society (ICICS 2018). The organizing commi2ee of the ICICS 2018 is high-
ly pleased to have nearly seventy abstracts submi2ed to the Conference. The
ICICS’s annual event is organized jointly by Indonesian Chemical Society and Re-
gional branch manager of the Indonesian Chemical Society. This year, 2018, offi-
cials from the Papua and West Papua branches were elected as organizers of this
internaPonal chemical conference. We are highly honored to host the event here
in Jayapura, Papua.
The aim of the ICICS 2018 is to promote interdisciplinary researches in

chemical sciences and technology, to encourage the development of chemical sci-
ences and technology for sustainable development, and disseminate research in
various fields of chemistry, natural sciences, and its related. The main theme of the
ICICS 2018 is “ Indonesia and Papua's Natural Resources for the World Welfare”,
with sub-themes “Sciences for Sustainable Development”. The conference deals
with Chemicals and Natural Sciences to fundamental and applied researches, in-
cluding all scopes and topics that are organic chemistry, inorganic chemistry, ana-
lyPcal chemistry, environmental chemistry, health sciences, biosciences and bio-
technology, pharmaceuPcal sciences, material sciences, mathemaPcs, and compu-
taPonal chemistry.
Finally, we would like to express our graPtude to Rector of University of

Cenderawasih, Dean of Faculty of MathemaPcs and Natural Sciences and all of the
sponsors for financial support and as a main sponsor of this event and thank the
Interna(onal Conference of The Indonesian Chemical Society 3
keynote and invited speakers as well as parPcipants for their contribuPon in mak-
ing the conference success. As general chairperson, I highly appreciate the great
effort of the members of the organizing commi2ee whose hard work really made it
possible to have this conference.
Jayapura, September 26, 2018
Yohanis Ngili
Chairperson, ICICS 2018
4
Organizing Committee Members
Dr. Frans A. Asmuruf SepAani Mangiwa, M.Si

Dr. Yohanis Ngili AlCons D. Sirampun, M.Si
Yane Ansanay, Ph.D Diana M Abulais, M.Si
Agnes E. Maryuni, M.Si Lodwyk N. Krimadi, M.Si
Organizing Committee Members

Yohanis I. Mandik, Ph.D Sriyanto, M.Si
Dr. Ilham Salim, M.Si Dr. AlbaiA, M.Pd
Dr. Johson Siallagan, M.Si Alex A. Lepa, M.Si
Dra. Elizabeth Holle, M.Si JukwaA, M.Si
Dra. Alowisya Futwembun, M.Si Frans Kafiar, M.Si
Yuliana R. Yabansabra, M.Si Catur F. Djarwo, M.Pd
Dr. Supeno Irwandi Y. Suaka S.Pd., M.Pd
Darwanta, M.Si.
Suwito, M.Si
Organized by:
Sponsored by:
CONTENT
Title Page
Preface 2
Organizing Commi2ee Members 4
Content 5
Welcoming Speech From Chairperson of The Organizing 10
Opening Remarks From University of Cenderawasih 12
Program Schedule of the 7th ICICS 13
Oral PresentaPon Schedule 16
Poster PresentaPon List 25
DisPnguished Keynote Speakers 28
DisPnguished Invited Speakers 29
Abstracts of Keynote Speakers 31
Abstracts of Invited Speakers 38
Abstracts of Oral PresentaPons 48
Abstracts of Poster PresentaPons 103
6
Sentani Airport
Jayapura City Sentani Lake
welcome
JAYAPURA
UNIVERSITY OF CENDERAWASIH
8
VENUE
THE GRAND ABE HOTEL

Wonderful
places to
Visit while in
Jayapura
HOLTEKAM BRIDGE
LOVE LAKE HOLTEKAM BEACH
BORDER HAMADI TRADITIONAL ART MARKET

10
WELCOMING SPEECH
FROM CHAIRPERSON OF THE ORGANIZING COMMITTEE
DisPnguish guests
1. Rector University of Cenderawasih, Dr. Ir. Apolo Safanpo, ST., M.T
2. Dean of Faculty of MathemaPcs and Natural Sciences, Dr. Dirk Y.P. Runtuboi,
M.Kes
3. Head of Research and Community Services (LPPM) University of Cenderawasih,
Dra. Rosye Tanjung, M,Sc., Ph.D
4. Keynote Speakers, Invited Speakers, ParPcipants, Sponsorships, ladies and gen-
tlemen.
Good morning and May Good be with us

It is my great privilege to greet you all to the 7th InternaPonal Conference of the
Indonesian Chemical Society (ICICS) 2018, Advances in Chemical Science: Indonesia
and Papua’s Natural Resources for the World Welfare, held in Indonesian Chemical
Society region Papua and Papua Barat along with Department of Chemistry Faculty
of MathemaPcs and Natural Sciences University of Cenderawasih, Jayapura, Indo-
nesia. I realize that you are all fully dedicated to sessions that will follow, but do
hope that you all will also take Pme to enjoy our fascinaPng Jayapura, with its cul-
tural trade mark, city of culture, baPk as well as its mulPcultural people.
Ladies and gentlemen, I recognize that this conference is principally de-
signed to enhance the contribuPon of chemical science to development of the oth-
er applied sciences related towards a more sustainable use of chemical substances
and natural resources. With this fast development of studies and researches on
chemical topics, we realize that chemistry highly contribute to applied sciences and
sectors, including medicine, pharmacy, agriculture, veterinary, and food as well as
health industries. In this case, I am very alert to the increasing needs to understand
chemistry in respect to biodiversity , rom molecular to ecosystem beneficial in the
improvements of human prosperity. Therefore, I wish that this event will be a great
opportunity and a wonderful venue for us to lay down a cooperaPve framework
and to establish scienPfic collaboraPon between scienPsts internaPonally. An im-
pressive roster of disPnguish speakers and a2endants from Japan, USA, Thailand,
and Indonesia has been gathered in this conference.
Hereby, on behalf of the Organizing Commi2ee, I acknowledge Prof. Nishi-

kagi M. Toshiaki, Ph.D (Chairman of Tokyo Noni Research Centre, Japan), Prof. Dr.
Supa Hannongbua (Kasetsart University, Thailand), Prof. Dr. Piyarat Boonsawang
(Prince of Songkla University, Thailand), Tatas H.P Brotosudharmo, Dipl.Chem., Ph.D
(Machung University, Indonesia), and Frans A. Asmuruf (University of Cenderawasih,
Indonesia) as keynote speakers, and also to these following invited speakers: Prof.
Dr. Yana Maolana Syah (InsPtut Teknologi Bandung), Dr. Agus Kuncaka, DEA
(Universitas Gadjah Mada), Prof. Dr. Harno Pranowo (Universitas Gadjah Mada),
Prof. Ni Nyoman Tri Puspaningsih (Universitas Airlangga), Prof. Dr. Drh. Maria Bin-
tang (InsPtut Pertanian Bogor), Dr. Hendra Wijaya (Center for Agro Based Industry),
Dr. Yusthinus Thobias Male (Universitas Pajmura), and Maureen G. Kumaunang,
M.Si (Prince Songkla University/Universitas Sam Ratulangi) for delivering their valua-
ble scienPfic informaPon.
To make this program happen, I would like to gratefully acknowledge to
valuable contribuPons from insPtuPonal sponsorship and funding including Govern-
ment of Keerom regency, Government of Jayapura city, PT. Freeport Indonesia, PT.
LNG BP Indonesia, Rector Universitas Cenderawasih, Department of MathemaPcs
and Natural Sciences Universitas Cenderawasih, Papua Bank, beloved seniors Dra.
Elizabeth Holle, M.Si and Drs. I Made Budi.
I also gratefully thank to the Indonesian Chemical Society and Dean and Vices Dean
of Faculty of MathemaPcs and Natural Science, University of Cenderawasih for giv-
ing us opportunity and support to organize this conference. Hearmelt thank is deliv-
ered to the Steering Commi2ee, the Academic Reviewers, members of the Organiz-
ing Commi2ee for their strong support, acPve parPcipaPon, cooperaPon, and hard
works throughout this year in preparing and organizing this meaningful meePng and
to those who have contributed their unPring effort in making this conference suc-
cess.
Despite our best efforts, it is inevitable that there is a lack in organizing this
conference and profoundly apologize to all speakers, oral and poster presenters,
a2endants, donators, and commi2ee members. Finally, I would like to offer my best
wishes for a highly enjoyable, successful, producPve and fruimul conference.
Thank you
Yohanis Ngili
12
OPENING REMARKS FROM RECTOR

UNIVERSITY OF CENDERAWASIH
DisPnguished guests, ladies and gentlemen,

On behalf of the University of Cenderawasih, I wish to congratulate and express my
graPtude to the Faculty of MathemaPc and Natural Science and to the Organizing
Commi2ee of the 7th InternaPonal Conference of the Indonesian Chemical Society
(ICICS) 2018: Advances in Chemical Science: Indonesia and Papua’s Natural Re-
sources for the World Welfare for succeeding this conference. My sincere thanks
are also addressed to Dean of MathemaPcs and Natural Science, Head of Depart-
ment of Chemistry-University of Cenderawasih, Prof. Nishikagi M. Toshiaki, Ph.D
(Chairman of Tokyo Noni Research Centre, Japan), Prof. Dr. Supa Hannongbua
(Kasetsart University, Thailand), Prof. Dr. Piyarat Boonsawang (Prince of Songkla
University, Thailand), Tatas H.P Brotosudharmo, Dipl.Chem., Ph.D (Machung Uni-
versity, Indonesia), and Frans A. Asmuruf (University of Cenderawasih, Indonesia)
as keynote speakers on this conference, all invited speakers to support this confer-
ence.
Chemistry is a core of fundamental science and the contribuPon of the applied
chemistry sectors on the naPonal economic development for Papua and Indonesia
needs to be strengthened through the effort of developing prospecPve domesPc
and export of potenPal chemicals, biodiversity, and biotechnology products as
menPoned in this conference theme. We sPll have some problems in chemicals,
biodiversity, and biotechnology sector and that is why, this conference is now be-
ing conducted.
I wish the meePng will be successfully bring the audience to exchange and brain-
storm the sciencific knowledge in order to provide valuable results for supporPng
the naPonal biodiversity and biotechnology development. I also strongly hope that
some ideas produced in conference will be applied for pracPcal applicaPon of
chemistry in Papua and Indonesia in near future.
Thank you and have a nice conference

Dr. Ir. Apolo Safanpo, ST., MT
Rector of University of Cenderawasih
PROGRAM SCHEDULE
THE 7th INTERNATIONAL CONFERENCE OF THE INDONESIAN CHEMICAL SOCIETY
ROOM : BALLROOM
Time AcAviAes
08.00-09.00 RegistraPon and Coffee Break
09.00-09.10 Singing of Indonesian Anthem
09.10-09.15 Speech by Chairperson of ICICS 2018 Commi2ee
09.15-09.20 Speech by Chair of the Indonesian Chemical Society
09.20-09.25 Papua TradiPonal Dance Performance

09.25-09.35 Speech by Rector of Cenderawasih University followed with
Opening ceremony
09.35-09.45 Opening dance by “Honong Dance Group’
09.45-10.15 PLENARY SESSION 1.
Prof. Dr. Supa Honnangbua
Moderator: Yohanis Irenius Mandik, Ph.D

Tatas H.P. Brotosudharmo, Dipl. Chem., Ph.D
Moderator: Yane O Ansanay, Ph.D
10.45-10.50 Papua TradiPonal Dance Performance
Prof. Dr. Piyarat Boonsawang
Moderator: Yohanis Irenius Mandik, Ph.D

14
Time AcAviAes
Dr. Frans Asmuruf
Moderator: Octolia Togibasa, Ph.D

Nishigaki M. Toshiaki, Ph.D
Moderator: Maria Simonapendi, M.Si.

12.20-13.20 Lunch Break and Poster Session
13.20-14.50 PARALLEL SESION 1

14.50-15.00 Coffee break
15.00-17.00 PARALLEL SESION 2
17.00-17.15 The best Oral Presenter announcement
18.30-finish Closing ceremony and Gala Dinner Hosted by Mayor of Jayapura

City
Closing ceremony and Gala Dinner Schedule
Time AcAviAes
18.30-18.35 Speech by Head of ICS Branch of Papua
18.35—18.40 Closing Speech by the Chairperson of the ICICS 2018
18.40-18.50 Closing Ceremony by the Mayor of Jayapura City
18.50-19.15 - Signing MoU Between Indonesian Chemical Society and Thailand
Chemical Society
- Awards
19.15- Dinner with the Mayor of Jayapura City
16
ORAL PRESENTATION SCHEDULE
ORGANIC CHEMISTRY & EDUCATION OF CHEMISTRY

Room: NAFRI 1
No. Time Code Presenter Title

1. 13.00- IS01 Prof. Yana M. Some Studies of Phytochemistry and
13.30 Syah Biological ProperPes of Three Indonesian
Meliaceae Species
3. 13.30- OP01 YanP Chemical Profiling of EssenPal Oil From
13.40 Zanthoxylum Acanthopodium Fruits And
Its AnPdiabePc Effect In Vitro And In
Vivo
4. 13.40- OP02 Bambang Pur- Synthesis And AcPviPes Test Of Curcu-
13.50 wono min Analogues DerivaPves As AnP-
Malarial Agents From Vanillin
5. 13.50- OP03 Elvira HermawaP Secondary Metabolites From One of The
14.00 Indonesian Medicinal Plants : Leaves of
Desmodium triquetrum Linn. (Fabaceae)
6. 14.00- OP04 Meiske Sangi DeterminaPon of Total Phenolic Content

14.10 and AnPoxidant AcPvity from Several
FracPons Ofaren’s (Arenga Pinata) Mid-
rib Flour
7. 14.10- OP05 Max R.J Phytochemicals Content and AnPoxidant
14.20 Runtuwene AcPvity of Some TradiPonal Medicinal
Plants
of Sangihe Ethnics in North Sulawesi
Province
8. 14.20- OP06 Dionysius Subali GC/MS IdenPficaPon of Tempeh Oil and
14.30 Its AnPphotoaging Effect in UVB-induced
8. 14.30- OP07 Effendi Development of Basic Chemical Module of

14.45 Thermodynamical Material with Stem Prob-
lem-Based Learning Approach for Study Pro-
gram of Chemical EducaPon Problem
9. 14.45- OP08 Florida Do- ReconstrucPon of Basic Chemistry Modul

14.50 loksaribu Based on Brainstorming Interac=ve
(BRAIN) to Enhance High Order Thinking
Problem Solving Papua Chemical EducaPon
Students
10. 15.00- OP09 Daniel Synthesis of 0-Carboxymethyl N-Palmitoil

15.10 Chitosan Which Useful As An Edible CoaPng
Film Through InteresterificaPon and Ami-
daPon ReacPons From Fa2y Acid
11. 15.10- OP10 Suyanta The Effect of Problem Based Learning Meth-
15.20 od on Students’ Learning Independence of
Chemistry Learning in High School
12. 15.20- OP11 A AlbaiP Increasing the Students CriPcal Thinking Skill
15.30 Through Voltaic Cell Laboratory AcPviPes
Based on Their Mental Model
13. 15.30- OP12 Kasmudin The Effect Of CooperaPve Learning Model
15.40 Mustapa Type Review Course Hooray (CRH) And
Jigsaw MoPvaPon and Learning Outcomes in
the Redox Materials Subject on Chemistry
EducaPon Tadulako University
13. 15.40- OP13 SepPani Man- Phytochemical Screening and AnPoxidant
15.50 giwa AcPvity of Methanolic Extract of Arabica
Roasted Coffee Beans from Wamena and
Moanemani
14. 15.50- OP14 Supriatno Cytotoxic Limonoids from The Stembark of

16.00 Chisocheton pentandrus (Meliaceae)
18
INORGANIC CHEMISTRY & PHYSICAL CHEMISTRY

Room: NAFRI 2

1. 13.00- IS02 Prof. Dr. Harno Curcumin Analogues as PotenPal AnP-
13.30 Dwi Pranowo Inflamatory Study of Molecular Docking,
Synthesis and in Vitro
2. 13.30- IS03 Dr. Agus kun- SynthePc Humus (Slow Release of Organ-
14.00 caka, DEA icParamagnePc FerPlizer) As The Best
AlternaPve to overcome Food Crisis
Caused by World PopulaPon ExploPon
3. 14.00- OP15 Ilham Salim TransesterificaPon of Used Cooking Oil

14.10 into Biodiesel Using NaN3/Modified Clay
Catalyst
4. 14.10- OP16 Henry F Ari- Synthesis of Silver NanoparPcles using
14.20 tonang Leaf Extract of Medicinal Plants and Anal-
ysis of AnPmicrobial AcPvity
5. 14.20- OP17 Alex Lepa The effect of ReacPon Time of
14.30 Hydrothermal Process on ModificaPon of
Natural Zeolite to Zeolite with RaPo of
Si/Al = 1
6. 14.30- OP18 Lukman Atmaja Pva/Chitosan-Montmorillonite Compo-

14.40 site For Fuel Cell ApplicaPon : Thermal
and Physical ProperPes on Specific Bal-
ance
7. 14.40- OP19 Rikson Asman Performance of Graphite/Graphana,
14.50 FerPles Siburian Manganese (Mn)/Graphite and Mn/
Grapheneas Electrode on Anodeof Pri-
mary Ba2ery
8. 15.00- OP20 Yane O Ansanay AcPvated Carbon to improve glucose
15.10 producPon from Switchgrass.

8. 15.10- OP21 YanP Kiding Allo Synthesis and CharacterizaPon of AcP-
15.20 vated Carbon from Sago Waste
(Metroxylon sagu) with ZnCl2 AcPvaPon
And HNO3 ModificaPon
9 15.20- OP22 Gesyth MuPara PreparaPon of Metal (ni,co)mo on sup-

15.30 Hikhmah Al porPng Material Indonesian Natural
Ichsan Zeolite
10. 15.30- OP23 Wahyu Praset- PreparaPon and Morphological Property
15.40 yo Utomo of Co3O4/ BaxSr1-xCo0.8Fe0.2O3-δ (x=0.5-
0.7) Composite Membranes using Starch
as Binder Agent
11. 15.40- OP24 IrdhawaP Anodic Stripping Voltametri for Determi-

15.50 naPon Lead (Pb) in Pok Choi Vegetable
12. 15.50- OP25 Darwanta ProducPon Fuel From PlasPc Waste
16.00 With Reactor of 50 kg Capacity and Its
Performance
13. 16.00- OP26 Roto Roto Surface ModificaPon and Characteriza-
16.10 Pon of Fe3o4@Sio2 For Recovery of Gold
14. 16.10- OP27 Rurini Study The Influence of DisPllaPonTime

16.20 RetnowaP on Component Profile of Sweet Fennel
Seeds (Foeniculum vulgare Mill. var.
dulce) EssenPal Oils and Its AnPbacterial
AcPvity against Staphylococcus aureus
15. 16.20- OP28 Diana M Abulais The Effect of Loading Zinc Oxideto The
16.30 Surface Supported by Magnesium Fluo-
ride
20
ANALYTIC AND ENVIROMENTAL CHEMISTRY

Room: YOKA 1

1. 13.00- IS 04 Dr. Hendra IsolaPon of α-Carotene, β-Carotene, α-
13.30 Wijaya Cryptoxanthin, and β-Cryptoxanthin from
Red Fruit Oil (Pandanus Conoideus Lam) by
Open Column Chromatography (OCC), Flash
Column Chromatography (FCC) and Prepara-
Pve Column Chromatography (PCC)
13.30- IS05 Yusthinus Mercury ContaminaPon from ArPsanal Gold

14.00 Thobias Male Mining in Buru Island , Indonesia
2. 14.00- OP29 Mohamad Rafi FtIR And Uv-Vis Spectrum Combined With
14.10 Chemometrics For IdenPficaPon And Au-
thenPcaPon Method Of Some Medicinal
Plants
3. 14.10- OP30 Allwar AdsorbPon of Phenol and 2-Clorophenol
14.20 From Aquaeous SoluiPon by AcPvated Car-
bon Derived from Banana Empty Fruit Bunch
by Hydrothermal-assisted KOH AcPvaPon
4. 14.20- OP31 P de Rozari An InvesPgaPon Into The Use of Sand Media

14.30 Planted With Thypa La=folia In Constructed
Wetland Ecotechnology In Removing Organic
Ma2er, Suspended Solids And Nutrients
From DomesPc Wastewater
5. 14.30- OP32 Indra Ajie Gun- CharacterizaPon of The Dominant Carote-
14.40 awan noids in Red Fruit Oil by Chromatography
and Spectroscopy Techniques
6. 14.40- OP33 Dyah IswanPni Chemical Profiling of Two Medicinal Plants,
14.50 Pradono Kaempferia rotunda and Garcinia cambogia,
using UPLC/QTOF-MS

7. 15.00-- OP34 Khairul Anam Drying Influence of Extract on Chem-
15.10 ical Content and Xanthine Oxidase
InhibiPon of Avicennia Marina
8. 15.10- OP35 Julius Pontoh ExtracPon and characterizaPon of

15.20 fish oil from various parts of snake-
head fish (Channa striata)
9. 15.20- OP36 Hubertus FabricaPon and Modeling Solar Cell

15.30 Ngaderman using Gowok Fruit (Syzygium poly-
cephalum) as SensiPzing and deposi-
Pon TiO2 exert Spin CoaPng Tech-
nique
10. 15.30- OP37 Hendrik O. Vapors Induced Phosphorescent
15.40 Lintang Changes in Molecular Self-Assembly
of Copper Pyrazolate Complexes for
Chemical Sensors of Methanol to
Hexanol
11. 15.40- OP38 Leny YuliaP Study on the InteracPons between

15.50 Nitrites, Nitrates, and Graphene Ox-
ide as a Fluorescence Sensor
12. 15.50- OP39 Meliana StandardizaPon of ExtracPon Meth-

16.00 Wahyun- ods of GelaPn From Lutjanus Sp.
ingtyas Scales
13. 16.00- OP40 E. HaryaP The Influence of CalcinaPon Tem-

16.10 perature to Mineral ComposiPon in
The Mangrove Crab Shells (Scylla
22

14. 16.10- OP41 Jhon D. Kalor FISH DIVERSITY OF MANGROVE ECO-
16.20 SYSTEM IN DEMTA GULF JAYAPURA
PAPUA
15. 16.20- OP42 Hendrawan PreparaPon and Physico-Chemical
16.30 ProperPes of Gracilaria/PVA/GA/CNT-
Based Hydrogel for Slow/Controlled
Release Material
BIOCHEMISTRY
Room: Yoka 2
Time Code Presenter Title

1. 13.00- IS06 Prof. Dr. Maria ExploraPon of EndhophyPc Bacteria to
13.30 Bintang, M.,S. Produce BioacPve Compounds
2. 13.30-- IS07 Prof. Dr. Ni Improving the Value-Added Agriculture
14.00 Nyoman Tri Biomass By EnzymaPc Bioconversion
Puspaningsih
3. 14.00- IS08 Maureen G. SelecPon of Promising HydrolyPc Halo-
14.30 Kumaunang, tolerant Producing Bacterialin the Sea-
M.Si. food FermentaPon Technology
4. 14.30- OP43 Verena AgusPni AnPbacterial AcPvity of Three Den-

14.40 drobiumspeciesfrom Papua Against
Eschericia coli and Staphylococcus au-
reus
5. 14.40- OP44 I Made Preclinical Trials of AnP-AtheroscleroPc
14.50 Sukadana Extract of Inocarpus Fagiferus Fosb
Seeds In Bali
6. 15.00- OP45 Alowis- AnPoxidant AcPvity Test of Extract In-
15.10 ya.Futwembun fusion from Stem of Yellow Rope
(Archangelsia.Flava.(L)Merr)
7. 15.10- OP46 Eva Susanty AnPcoagulan AcPvity of Ethanolic Ex-
15.20 Simaremare tract SPngging Ne2le
(Laporteaaestuans (L) Chew) from Biak
8. 15.20- OP47 Henderina J Victoria Ground Pigeon(Goura victoria)

15.30 Keiluhu and Their Food Plants in The Nim-
bokrang Forest Areaof Jayapura-Papua
24

9. 15.30- OP48 Susilo TB PopulaPon Analysis of D-loop mtDNA Buffalo
15.40 (Bubalus bubalis & Syncerus caffer) Sequenc-
es From Gen-Bank DDBJ
10. 15.40- OP49 Rani Dewi AnPbacterial AcPvity of Daun Afrika Extract
15.50 PerPwi (Vernonia Amigdalina ) Papua to Staphylo-
coccus aureus and Escherichia coli Bacteria
11.. 15.50- OP50 Elsye Gun- Test AnPcoagulant AcPvity Ethanol extract
16.00 awan daun jilat (Villebrunea rubescens) Against
Human Blood
12. 16.00- OP51 Yohanis Mitochondrial genome mutaPon analysis:

16.10 Ngili Papuan mtG comparaPon with several
GenBank sequence data on gene control and
encoding regions
13. 16.10- OP52 Supeni NutriPon and anPoxidant properPes of Pleu-
16.20 SufaaP rotus sajur-caju Mushroom
from Jayapura, Papua
14. 16.20- OP53 Yohanis I CharaterizaPon of Microalgae from Freshwa-
16.30 Mandik ter Pond of Buper Jayapura and from Sea-
water of Harlen Beach Jayapura Based on
Their Lipids, Chlorophylls, Protein, and Car-
bohydrate Contents
15. 16.30- OP54 Agnes Eri Coconut Oil ProducPon via Coconut Cream
16.40 Maryuni FermentaPon by Lactobacillus bulgaricus
POSTER PRESENTATION LIST
No. Code Name Title

1. PP01 Matheis FJDP PreparaPon of chitosan with variaPons of molec-
Tanasale ular weight and its effect on depolymerizaPon of
chitosan with hydrogen peroxide using micro-
wave technique
2. PP02 M. Miqdam Synthesis of magnePte/TiO2-Cu as recoverable
Musawwa1 and sensiPve photocatalyst under visible light
radiaPon
3. PP03 Nurcahyo Iman Study and FormulaPon of Anionic Surfactant for

Prakoso Enhanced Oil Recovery
4. PP04 Tatang Shabur The Influence of FermentaPon Time and Cellulase

Julianto Enzym Volume of Oyster Mushroom Stem at Bio-
ethanol ProducPon from Rice Straw Using Simul-
taneous SaccaharificaPon and FermentaPon (SSF)
Method
5. PP05 Wiyogo P. Green Synthesis of Gold-Palladium Core-Shell
Wicaksono NanoparPcles (Au@Pd CSNPs) Using Citrus Peel
Extract
6. PP06 Henry Fonda AnPmicrobial of bacterial cellulose/ZnO/Ag Nano-

Aritonang composite Membrane
7. PP07 Irmanida Extract of Zingiberaceae Leaves Steam DisPllated

Batubara Residue as AnP-bacterials and Biofilm Degradator
8. PP08 Noor Fitri The ExtracPon of Antocyanin Pigment from Egg-

plant Peels (Solanum melongena L.)and Its Appli-
caPon as Natural Acid Indicator
9. PP09 Sri Handayani Quality Test of Natural Bath-Soap with Clove Oil
and Its AnPbacterial AcPvity Against Staphylococ-
cus Epidermidis
26
No. Code Name Title

10. PP10 Cecep Sa’bana Improving Waste Management performance
RahmaPllah of Laboratory Indonesian Islamic University
(UII) Using Techniques AcPvated Carbon Ad-
sorpPon and CoagulaPon with Aluminum Poly
11. PP11 Tohari AcPve Charcoal EffecPveness Of Leather Cassava

As Cu Ion Adsorbent In Waste Water at Integrat-
ed Laboratory Indonesian Islamic University (UII)
12. PP12 Norra Gus Pri- OpPmizaPon of DisPllaPon Ginger Emprit using
ambodo Methods of Boil And ModificaPons
13. PP13 Is FaPmah

Physicochemical EvoluPon of Silica from Salacca
Leaves for AdsorpPon
14. PP14 Johnly Alfreds Analysis Of Ferrous Ion Species In Cinnamomum
Rorong burmanii Leaves As BiosensiPzer
In Iron PhotoreducPon Process Using Fluorocent
Light
15. PP15 YaP MaryaP EmulsificaPon for FormulaPon of Natural Folic
Acid Supplements prepared from Soybean
Tempe (Glycine soya L.) and Fermented Spinach
(Amarantus sp) for the Needs of Pregnant
Women
16. PP16 Dede Sukandar IdenPficaPon of Chemical Content and AcPvity of
EssenPal Oil of Citronella Wangi (Cymbopogon
nardus) Against Staphylococcus aureus and Esch-
erichia coli Bacteria
17. PP17 Iwan Aminudin EfecPvity and CharacterisPc Citronella
(Cymbopogon nardus L.) Oil LoPon as Mosquito
Repellent
18. PP18 Habibi Hidayat AnPbacterial AcPvity Test of Klebsiella pneumo-

nia from Tomato Fruit Extract (Solanum lycopersi-
cum L.) as a prevenPon of Pneumonia
No. Code Name Title

19. PP19 Lilis SiP Aisyah1 AnPbacterial AcPvity of Some Extracts (Kalanchoe
millo=i)
20. PP20 Fri RahmawaP Phytochemical and BioacPvity of Ethanol Extract

of Cauliflower
(Brassica Oleracea Var. BotryPs)
21. PP21 Euniche R.P.F. Comparison of PhyllogenePc MSP 1 Jayapura,
Ramandey Papua and Central Sumba, NTT
22. PP22 Dwi HudiyanP DeterminaPon EncapsulaPon Efficiency Beta Car-

otene and Vitamin C In Liposomes of Coconut
23. PP23 Parsaoran Si- InhibiPng of InteracPon between E-Cadherin...E-

ahaan Cadherin Protein by Cyclic PepPde ADTC4 (Ac-
CDDTPC-NH2) Inhibitor Simulated on 120 ns
24. PP24 PurbowaPningru ANTIOXIDANT ACTIVITY FROM METABOLITE OF
m R Sarjono Carica papaya ENDOPHYTIC BACTERIA
25. PP25 Yusmaniar AdsorpPon of Eosin Y Dyes Using Modified Silica

Gel Composites
3-aminopropyltriethoxysilane (APTES) - AcPve
Carbon from Natural Resources
26. PP26 Maria PrasPowa- Analysis of Students AuthenPc Assesment in
P Chemistry Through Flipped Classroom Model
27. PP27 Winarto Haryadi THE SYNTHESIS OF 2'-HYDROXY-4-METHOXYCHALCONE, 4'-

METHOXYLAVONE, 2'-HYDROXY-4-CHLOROCHALCONE AND 4'-
CLOROFLAVANONOL AND THEIR IN VITRO ACTIVITY TEST
28. PP28 Dewa Gede Katja Phytochemical and anPoxidant ACTIVITIES IN

EXTRACT n-hexan, Ethyl Acetat and Methanol
SKIN BTANG Chisoceton sp.(Meliaceae)
29. PP29 Wahyuni Karunia Mechanical and Chemical CharacterisPcs of Car-

Dewi rageenan Based Edible Film from Red Seaweed
(Euchema sp.) from Biak (Papua) with Sorbitol as
28
Prof. Dr. Supa Honangbua Tatas H.P. Brotosudharmo, Dipl. Chem., Ph.D
Kasetsart University, Thailand Machung University, Indonesia
KEYNOTE
SPEAKERS
Prof. Dr. Piyarat Boonsawang

Prince of Songkla Univ., Thailand
Dr. Frans AgusAnus Asmuruf

University of Cenderawasih,
Indonesia
Nishigaki M. Toshiaki, Ph.D

Tokyo Noni Research Center, Japan
Prof. Dr. drh. Maria Bintang, M.S.

Bogor Agricultural University
INVITED SPEAKERS
Prof. Dr. Harno Dwi Pranow

University of Gajah Mada
Prof. Dr. Yana Maolana Syah

Bandung InsAtute of Technology
Dr. Agus kuncaka, DEA
University of Gajah Mada

30
Prof. I Nyoman Tri Puspaningsih

University of Airlangga
Dr. YusAnus Tobias Male, S.Si., M.Si.

University of Padmura,
Dr. Hendra Wijaya

Center for Based Agro Industry
Maureen G. Kumaunang, M.Si.

Prince of Songkla University, Thailand
ABSTRACTS OF KEYNOTE SPEAKERS

32
KS01
3D-Molecular Structural Databases from Thai Natural Products and its Applica-
Aons in Drug Discovery Research
Patchareenart Saparpakorn1,2, Chak Sangma1,2, Duangmanee Chuekeaw1, Supa

Hannongbua1,2*,
1
Department of Chemistry, Faculty of Science, Kasetsart University, Bangkok, 10900, Thailand
2
Center for Advanced Studies in Nanotechnology for Chemical, Food and Agricultural Indus-
tries, Kasetsart University, Bangkok, 10900, Thailand
*Corresponding author: fscisph@ku.ac.th
Southeast Asia has been rich of biodiversity, therefore, Natural products have in-
creasingly a2racted much a2enPon as a valuable resource for the development of
bioacPve compounds for drug discovery and development as medicines due to the
structural novelty and good bioavailability. Digital technology provides opportunity
to the collecPon of molecular structures of bioacPve compounds from Natural pro-
ducts with the physico-chemical properPes obtained from both experimental and
calculated data. This necessitates a comprehensive database for the natural pro-
ducts and the fracPonal extracts whose biological acPviPes have been verified. The
first structural database of Thai medicinal plants, Chemiebase, has been built as a
plamorm for virtual screening, using knowledge from Thai tradiPonal medicine and
consisted of about 4,000 acPve compounds. Some examples using data from this
database and other computer-aided molecular design methods to raPonalize Thai
tradiPonal medicine are also presented, starPng with virtual screening exercised on
anP-SARS Corona Protease, anP-HIV-1 reverse transcriptase, anP-HIV-1 protease,
anP-influenza A neuraminidase, and anP-cyclooxygenase (COX), candidates. The
second example consists of the use of molecular modeling to propose drug mecha-
nism for anP-tumor compounds, anP-TB, anP-Alzheimer, etc. The database has
been successfully used to screen for novel acPve compounds. Therefore, extension
of this database can be done by addiPon of reported bioacPve compounds from
Thailand such as Mushrooms as well as other regions in Malaysia and Indonesia. At
the end, data science and analyPcs using this available database can be benefit to
an advancement of Natural Products for future drug discovery against emerging
diseases in more effecPveness and efficient to the well being of mankind.
Keywords: Natural products, molecular databases, bioacPve compounds, tropical

diseases, molecular modeling, computaPonal chemistry
K02
Carotenoids from the Indonesian ExoAc Species
Indra A.Gunawan1, Jovine M. Kuriawan1, Arif A. Wibowo1, Edi SePyono2, Heri-

yanto1,2, Yuzo Shioi2, KonstanPna M.B. Kameubun4, Leenawaty Limantara2,3, and
Tatas H.P. Brotosudarmo1,2*
1
Department of Chemistry, Faculty of Science and Technology, Universitas Ma Chung, Jl.
Villa Puncak Tidar N-01, Malang 65151, East Java, Indonesia
2
Ma Chung Research Center for Photosynthe=c Pigments (MRCPP), Universitas Ma Chung,
Jl. Villa Puncak Tidar N-01, Malang 65151, East Java, Indonesia
3
Center for Urban Studies, Universitas Pembangunan Jaya, Jl. Cendrawasih Rata B7/P,
South Tangerang 15413, Banten, Indonesia
4
Biology Educa=on Department, Faculty of Teacher Training and Educa=on, Cenderawasih
University
*Corresponding author: tatas.brotosudarmo@machung.ac.id
Carotenoids are a family of yellow to orange-red pigments, structurally consisted

of 40-carbon atom to form 8-isoprene skeletons. Currently there are more than
500 carotenoid structures have been fully elucidated. Carotenoids are very inter-
esPng system. Their conjugated double-bond system determines the light-
absorpPon properPes and chemical reacPvity that form the basis of most func-
Pons. Specifics interacPons with other molecules in the immediate vicinity strong-
ly influence the properPes of a carotenoid and are also crucial to funcPoning. Ca-
rotenoids play important role in the photosynthesis reacPons, i.e. to harness the
sunlight energy, to transfer the excited energy to chlorophylls, and responsible
for photo-protecPon such as in protecPon against UV- and blue-ray, singlet oxy-
gen scavenging and quenching of chlorophyll triplet states. Our group works in
determinaPon of carotenoids from Indonesian natural resources, e.g. red fruit
(Pandanus conoideus), a n indigenous plant in Papua Island, marigold flower
(Tagetes erecta L.), a religious significant flower of Balinese Hindus, brown algae
(Phaeophyceae), and a coral endophyPc symbiont (Erythrobacter sp.). We are
working with carotenoids such as as b-carotenone, semi-b-carotenone, lutein,
fucoxanthin, and sulfated carotenoids. In this presentaPon, we would like to in-
troduce the wide variety carotenoid, funcPons in photosynthesis reacPon and
funcPons in human health, efforts to determine the structure in various indige-
nous species, and the study about its aggregaPon properPes in organic solvent,
nanoparPcles and in the naPve pigment-protein complex.
Keywords: aggrega=on, carotenoid, chromatographic separa=on, spectroscopic
determina=on
34
K03
Biogas PurificaAon Using BiofiltraAon System

Piyarat Boonsawang
Faculty of Agro-Industry, Prince of Songkla University, Songkhla, Thailand, 90112
E-mail address: piyarat.b@psu.ac.th
Abstract
Hydrogen sulfide (H2S) is one of the major problems in biogas uPlizaPon because it
is highly corrosive gas and damages the equipment including pipelines, cogenera-
Pon engines, and microturbine units. During the anaerobic digesPon of sulfate rich
feedstock, H2S can be generated ranging from 1000–30000 ppmv. Therefore, the
biogas cleaning is criPcally important for its diverse end use. Biofilter system is a
promising biological method for H2S removal due to several merits including low
energy consumpPon, ease of process scale-up, and low operaPng and capital
costs. In this process, the polluted gas is passed through packing media in a bio-
reactor, which the liquid is conPnuously recirculated through the packing media.
The recirculaPon media provides moisture, nutrients, pH control to the biofilm,
and allows the removal of inhibiPng products. Sulfur oxidizing bacteria (SOB) are
the key microbial group involved in biological oxidaPon of sulfide into elemental
sulfur (S0) and/or sulfate (SO42−) in biofiltraPon system. The efficiency for H2S re-
moval and type of the end products depends on many factors including oxygen/
sulfide raPo, the iniPal H2S concentraPon, type of packing material, the microbial
consorPum, empty bed retenPon Pme.
Kerwords: biogas, purificaPon, biofiltraPon

K04
Quantum Chemical CalculaAons of The Spectroscopy of Core Electrons
Frans A. Asmuruf1 and Nicholas A. Besley2*
1
Department of Chemistry, Faculty of Science and Mathema=cs, Universitas of
Cenderarwasih, Kampus Uncen Baru Waena, Jayapura, 99351 Papua, Indonesia
2
School of Chemistry, University of Nogngham, University Park, Nogngham, NG7
2RD, UK.
*Corresponding author: nick.besley@nojngham.ac.uk
The spectroscopy of core electrons is a2racPve for several reasons. The spaPally
local nature of the core orbitals and large energy difference between the core orbit-
als of different elements means that the spectroscopic techniques can provide an
atom specific probe of electronic structure. Recent advances in X-ray sources have
led to a renaissance in spectroscopic techniques in the X-ray region. These tech-
niques that involve the excitaPon of core electrons can provide an atom specific
probe of electronic structure and provide powerful analyPcal tools that are used in
many fields of research. TheorePcal calculaPons can o|en play an important role in
the analysis and interpretaPon of experimental spectra. In this perspecPve, we re-
view recent developments in quantum chemical calculaPons of X-ray absorpPon
spectra, focusing on the use of Pme-dependent density funcPonal theory to study
core excitaPons. The pracPcal applicaPon of these calculaPons is illustrated with
examples drawn from surface science, bioinorganic chemistry, and large systems
such as fullerenes.
Keywords: quantum calcula=ons, core electrons, TDDFT, spectroscopy

36
K05
Buah Merah (Pandanus conoideus) from Papua, Indonesia

Toshiaki M. NISHIGAKI, Ph. D.
M&K Laboratories Inc.
School of Medicine, Shinshu University, JAPAN
E-mail:
It was in August of 2005 when I could visit Papua first Pme. Papua is Paradise-
Bird island rich in natural resources covered with dense unexplored forest and sur-
rounded by blue sea. There are more than 200 naPve tribes who are our human
ancestors of Homo-Sapiens reached to this island 60,000 years ago. A part of Papu-
an people might move to Japan 20,000 years ago and become Jyomon-jin, ances-
tors of our present Japanese.
When we fly from Sentani airport to higher mountain area, we arrive at Wame-
na in Baliem valley, which looks like Shangri-La and completely different country
introduced to the world in 1938. People in Baliem valley have been surviving under
the severe environments for at least 30,000 years. Now it is well-known that the
secret food for their survival under cold climate and poor animal origin foods is
Buah Merah, Red fruits. Buah Merah is exclusively naturally grown in Papua.
Immediately a|er I encountered Buah Merah in Baliem valley in 2005 and I had
decided this fruit must be my second subject to study in my remaining life following
a|er Mengkudu. Buah Merah put on fire to my curiosity.
In 2006, our Buah Merah co-working team with Nagasaki University in Japan
disclosed the richest presence of novel micronutrients, beta-cryptoxanthin as well
as alfa- and beta-carotene, and alfa-cryptoxanthin. This was the first discovery in
the world.
We also demonstrated that the enPre profile of nutriPon in Buah Merah oil and
revealed rich in quality oil including Omega-3, 6 and 9 and vitamin E and beta-
phytosterol. Ingredient rates of Buah Merah oil fa2y acids are compaPble with
those of animal fats. These oil and lipophilic and carotenoids nutrients seem to be
essenPal that Papuan folks living at the higher mountain areas have been surviving
for a period of 30 millennium.
At the end of 20 century, intervenPon studies by excess and synthePc beta-
carotene dosage were found to increase in lung-cancer risks. From these results,
the next quesPon occurred what acPve ingredient in green-yellowish vegeta-

bles and fruits to prevent lung cancer was. The answer is beta-cryptoxanthin.
We examined the effects of Buah Merah oil against lung cancers in in vitro and
in vivo studies using human lung cancer cells (H549). Both studies demonstrated
inhibitory acPons against H549 cellular line. American team disclosed that beta-
cryptoxanthin administraPon to smoking ferrets prohibited squamous metaplasia
and cellular signals related to cancer dose-dependently. Almost of all the epidemi-
ological studies suggest beta-cryptoxanthin is a promising micronutrient to prevent
lung cancers.
In addiPon to effect of beta-cryptoxanthin against lung cancer, deficiency of
beta-cryptoxanthin is associated with several diseases such as diabetes mellitus,
cervical squamous cell carcinoma, rheumatoid arthriPs, inflammatory polyarthriPs,
liver dysfuncPon, atherosclerosis, esophageal cancer, DNA oxidaPon damage and
so on.
My curiosity moved to the other social problems in beauty and aging in Japan.
We have been conducPng preliminary studies with human subjects for post-
menopausal osteoporosis, Acne vulgaris and alopecia. The results suggest that
Buah Merah oil can improve these condiPons. In in vitro study, Buah Merah oil
revealed anP-hypermelanogenesis by unique mechanisms.
The above effects of Buah Merah oil shall be confirmed by further researches
and clinical trials.
Buah Merah is rare funcPonal and natural fruit exclusively culPvated in Papua
and seems to be one of idenPPes of Papua people. Its fruit oil can be properly pro-
cessed and manufactured in stable and easily accessible forms. Indonesian govern-
ment recognized the merits of Buah Merah oil and gave an award of Indonesia in-
novaPon funcPonal food to Buah Merah oil product at IID 2017 program.
It is my desire that Buah Merah can be contributed to human health as anP-
aging supplement in the world and to welfare of Papuan people.
Keywords: buah merah, Papua

38
ABSTRACTS OF INVITED SPEAKERS

IS01
Some Studies on Phytochemistry and Biological ProperAes of Three Indonesian
Meliaceae Species
Yana M. Syah,a Rahmi RachmawaA,a Iin A. Sitohang,a Ni Komang T. Dharmayani,b
MiranA B. Bumi,a Leny HeliawaA,c Elvira HermawaAa
a
Organic Chemistry Division, Ins=tut Teknologi Bandung, Jalan Ganesha 10, Ban-
dung, Indonesia
b
Department of Chemistry, Mataram University, Jalan Majapahit 62, Mataram,
Indonesia
c
Department of Chemistry, Pakuan University, Jalan Pakuan, Bogor, Indonesia
Meliaceae is a large plant family, consisPng of 46 genera and about 560 species.
Among of them, Lansium domes=cum (‘Duku’, ‘Langsat’, or ‘Kokosan’), Sandoricum
koetjapi (‘Ketjapi’) and Dysoxylum densiflorum (‘Majegau’) are of important species
in Indonesia. Lansium domes=cum and S. koetjapi produce edible fruits which of
significant economic value to the local people, while D. densiflorum is an iconic
plant of Bali Island due to the wood is used for construcPons of holy buildings. Pre-
vious chemical invesPgaPon on the three plants showed the presence of typical
Meliaceaous secondary metabolites, namely triterpene and limonoids derivaPves.
Because these plants are endemic in Indonesia, we have an opportunity to do
some chemical invesPgaPon on these plants: L. domes=cum var. kokosan (seed
and fruit peels), S. koetjape (seed, fruit peels, and roots) and D. densiflorum
(leaves). Twenty six compunds had been isolated, including ten new triterpenes
and limonoids, namely kokosanoic acid (1) from the fruit peels of L. domes=cum
var. kokosan, koetjapins A-D (2-5) and koetjapoic acid (6) from the seeds and ruit
peels of S. koetjape, respecPvely, and a calamenol derivaPve 7 and densiflorinic
acids A-C (8-10) from the seed and leaves of D. densiflorum, respecPvely. The
structures of these compounds were determined mainly by extensive 1D- and 2D-
NMR spectra and supported by their high resoluPon mass spectral data. Prelimi-
nary evaluaPon for anPbacterial acPvity to the isolated compounds showed that
most of the compounds exhibited moderate to weak acPviPes, except that the cal-
amenene derivaPves (such as compound 7) gave significant acPviPes to Bacillus
subs=lis and Shigella dysenteriae (MIC 3.12 mM). The calamenene derivaPves were
also showed significant inhibiPon to the growth of brown- and white-rots compare
to the
40
triterpenic acid derivaPves isolated from D. densiflorum. We also have an oppor-

tunity to test the isolates of D. densiflorum as an anPfeedant against Coptotermes
formosanus showing that only compound 7 that exhibited strong anPfeedant acPv-
ity. In conclusion, twenty six compounds had been isolated from the three Melia-
ceous plants of Indonesia, most of which were moderate to weak anPbacterials,
and only calamenene derivaPves isolated rom D. densiflorum that showed signifi-
cant acPviPes against the growth of brown- and white rots and as anPfeedant
properPes.
Keywords: phytochemistry, biological properPes, Meliaceae

IS02
Curcumin Analogues as PotenAal AnA-Inflammatory: Study of Molecular Docking,

Synthesis and In Vitro
Harno D Pranowo1, Mario R Sohilait1,Winarto Haryadi1, Thomas S. Hofer2

1
Department of Chemistry, Faculty of MathemaPcs and Natural Sciences, Universi-
tas Gadjah Mada, Jl. Sekip Utara, Yogyakarta 55281, Indonesia.
2
TheorePcal Chemistry Division, InsPtute of General, Inorganic and TheorePcal
Chemistry, University of Innsbruck, Innrain 80-82, A-6020 Innsbruck, Austria
E-mail:
A virtual screening of curcumin analogues was carried out via docking of

designed compounds into the COX-2 binding site to predict whether these com-
pounds demonstrate an increased binding affinity to the COX-2 target. The results
of the molecular docking studies imply that aromaPc rings with electron-
withdrawing groups bound to the curcumin ring would generate more potent anP-
inflammatory agents, which can serve as potenPal leads for further anP-
inflammatory studies. In parPcular, the molecular docking study showed that the
CH3O, OH, NO2, and OCH2O subsPtuents of curcumin analogues were located deep
inside the binding-pocket of the COX-2 acPve site, where the O-atoms of the re-
specPve groups formed H-bonds with the atoms of His90, Arg513, Met522, Ser530,
Gly526, Phe518, Gln192, Leu353, Ser353 and Tyr355. By prioriPzing the result of the
molecular docking it is possible to idenPfy the most promising compounds for syn-
thesis. A simple an efficient synthesis of a novel curcumin analogue, namely 1-(3,4-
Dimethoxy-phenyl)-5-(4-nitro-phenyl)-penta-1,4-dien-3-one was developed and
confirmed with spectroscopic techniques. The compound exhibited remarkable anP
-inflammatory acPvity comparable with that of diclofenac sodium, exhibiPng a very
high percentage inhibiPon at concentraPons in the range of 100 to 600 µg/ml, com-
pared to diclofenac sodium.
Keywords: curcumin analogues, an=-inflammatory, molecular docking, synthesis, in

vitro
42
IS03
SyntheAc Humus (Slow Release of Organic ParamagneAc FerAlizer) as the Best

AlternaAve to Overcome Food Crisis Caused by World PopulaAon Explosion
Agus Kuncaka1, Aulia Wahyuningtyas2, Roto1

1
Department of Chemistry, Universitas Gadjah Mada, Yogyakarta
2
Department of Chemistry EducaPon, Surya College of EducaPon, Tangerang,
Banten
email: akuncaka@ugm.ac.id / aulia.wahyuningtyas@stkipsurya.ac.id
There have been synthesized the material nature humus-like called syn-
thePc humus named Slow Release of Organic ParamagnePc (SROP) FerPlizer. This
material has the ability to increase soil organic ma2er content, stable in the soil
and affect to soil ferPlity. The SROP made of biochar, hydrochar, biomolecules and
superparamagnePc parPcles mixture through the new road of humificaPon. This
method produce a stable material rich in carbon, nitrogen, oxygen and macro-
micronutrients that plants need to grow up perfectly. The SROP was extracted us-
ing IHSS method to get synthePc humin as the most stable humus fracPon. This
study conducted a thorough synthePc humin characterizaPon using 13C NMR, FTIR,
XRD, SAA and TEM. The SROP has ability to adsorb biomolecule tested through ex-
perimental glucose adsorpPon.
The results showed synthePc humin is an amorphous material with meso-
porous parPcle size that rich by carbon in a stable aromaPc form, and oxygen en-
riched on the surface of synthePc humus. It is also contains silica from rice husk
and Fe as superparamagnePc parPcle. Humin synthePc has the ability to adsorb
glucose, which means synthePc humin and SROP generally can act as hosts for glu-
cose and other biomolecules that exist in the soil.
Keywords: SROP, humifica=on, synthe=c humus, synthe=c humin, glucose adsorp-

=on.
IS04
MERCURY CONTAMINATION FROM ARTISANAL GOLD MINING IN BURU ISLAND,

INDONESIA
Yusthinus Thobias Male1,* , Amanda Reichelt-Brushek2

1
Department of Chemistry, Faculty of Mathema=cs and Natural Sciences, Pagmura
University, Ambon, Indonesia.
2
Marine Ecology Research Centre, School of Environment, Science and Engineering,
Southern Cross University, Lismore NSW, Australia.
*
Corresponding author: yusmale@fmipa.unpaj.ac.id
In November 2011 gold was found in large quanPPes at “Gunung Botak”, Buru Is-
land, Mollucas Province, Indonesia. The local landowners invited illegal miners to
set up operaPons for gold extracPon. More recently mercury has been used in the
trommel method to extract gold from the ore. This requires large volumes of water
for flushing and results in the deposiPon of mercury into the upper catchment of
the Way Lata river system. There are over 2000 trommels on the river banks all us-
ing mercury for gold extracPon. Total mercury in waste ponds was over 680 mg/kg.
In sediments at the mouth of the local river and a small feeder creek >3.00 mg/kg
and 7.66 mg/kg respecPvely. River and bay sediments were proporPonately higher
in in available mercury than elemental mercury and more strongly bound mercuric
sulphide compare to that in trommel waste. From this there is potenPal for food
chain contaminaPon and because of the close relaPonship of the villagers with the
envrionment in relaPon to food resources and food security there is further risk of
human health concerns.
Key Words: Gunung Botak, gold extracPon, mercury, trammel, envrionment

44
ISO5
IsolaAon of α-Carotene, β-Carotene, α-Cryptoxanthin, and β-Cryptoxanthin from
Red Fruit Oil (Pandanus Conoideus Lam) by Open Column Chromatography (OCC),
Flash Column Chromatography (FCC) and PreparaAve Column Chromatography
(PCC)
Hendra Wijaya, Ning Ima Arie Wardayanie, Dyah Aninta KusAarini, Nami Lestari,
Fitri Hasanah, Moh. Maman Rohaman, Lukman Junaidi, Rhoito Frista Silitonga,
SanA Ariningsih, Dedy Darmawan Samid, Neneng Dina Darlianty, Indri NovianA
Balai Besar Industri Agro (BBIA)
Jl. Ir. H. Juanda No. 11, Bogor 16122
E-mail: faizawijaya@gmail.com
Red fruit oil (Pandanus conoideus Lam) contains acPve components of carotenoids
namely α-Carotene, β-Carotene, α-Cryptoxanthin, and β-Cryptoxanthin. Isolate of
these compounds can be used for food, pharmaceuPcal, chemical standard reagent
needs for analysis so that it is needed to develop isolaPon techniques. The meth-
ods used to isolate each of these compounds were Open Column Chromatography
(OCC), Flash Column Chromatography (FCC), and PreparaPve Column Chromatog-
raphy (PCC). The verificaPon methods of isolaPon performance used were KLT,
spectrophotometer, and HPLC-UV. Based on the results of evaluaPon and opPmiza-
Pon, it was obtained that the isolaPon condiPons by OCC method were silica gel
staPonary phase 64-210 µm, mobile phase hexane: acetone (7:3) flow rate of 15
drops/minute. The isolaPon condiPons by FCC method were Buchi Flashpure
Ecoplex Silica 12 g column, hexane solvent: ethyl acetate (9: 1) and flow rate of 30
mL/minute. The isolaPon condiPons by PCC method were MeOH / MTBE / H2O
mobile phase with gradient eluPon (81/15/4) gradually changing to (6/90/4) for 30
minutes. FCC and PCC method can isolate each compound of α-carotene, β- caro-
tene, α- cryptosanthine, and β- cryptosanthine. OCC method can isolate α/β-
carotene from α/β-cryptosanthine and has not isolated alpha from beta carotene
as well as alpha from beta cryptosanthine.
Keyword: red fruit oil, α-Carotene, β-Carotene, α-Cryptoxanthin, and β-
Cryptoxanthin, OCC, FCC, PCC
IS06
ExploraAon of EndophyAc Bacteria to Produce BioacAve Compounds
Prof. Dr. drh. Maria Bintang, MS

Department of Biochemistry, Bogor Agricultural University, INDONESIA
Email: maria_bintang@yahoo.com
ABSTRACT
Some medicinal plants are known to produce bioacPve compounds. Endophytes
are microorganism which live inside plant Pssues and do not show negaPve effect
to their host plant. UPlizaPon of bioacPve compounds from plant extract need a
large biomass. Instead, we can use endophyPc bacteria which are known to pro-
duce agrochemicals, anPbioPcs, anPparasiPcs, anPoxidants, anPdiabePc and anP-
cancer agents. It is an opportunity to get bioacPve compounds which are natural,
inexpensive and environmentally friendly. But we sPll need more comprehensive
studies on the chemistry and biology of the bioacPve natural products which are
produced by endophytes.
Keywords: bioac=ve compound, endofi=c bacteria, medicinal plants

46
IS07
IMPROVING THE VALUE-ADDED OF AGRICULTURE BIOMASS BY ENZYMATIC BIO-

CONVERSION
Ni Nyoman Tri Puspaningsih1,2

1
Departement of Chemistry, Faculty of Science and Technology, 2Proteomic Labora-
tory, InsPtute of Tropical Disease , Universitas Airlangga, Kampus C Mulyorejo, Su-
rabaya, East Java 60115, Indonesia.
ni-nyoman-t-p@fst.unair.ac.id; nyomantri@yahoo.com
The agriculture biomass is mainly composed of lignocellulose material, generally

consisPng of celluloses (45-55 %), hemicelluloses (35-40%), and lignins (5-20%),
which can be uPlized as a substrate for biotechnological conversion. Large amounts
of lignocellulosic waste are generated through forestry and many agro-industries
and they pose an environmental polluPon problem. The esPmated total of oil palm
waste biomass in Indonesia produced is around 100 million ton/ha/year. Indonesia
also produces other types of agriculture biomass around 70 million ton/year from
rice straw, corn biomass, soybean biomass and cassava. The majority of agriculture
biomass is uPlized as solid fuels for energy generaPon, as organic ferPlizer in the
form of composts and substrate for animal feed, chemical feed-stocks and building
material. Bioconversions of lignocellulosic biomass will involve the use of enzymes,
microbes (wild-types or recombinants) or other biological agents, individually or in
combinaPon. The main enzymes produced by lignocellulolyPc bacteria and fungi
are cellulases, hemicellulases, pecPnases and ligninases.
Keywords: Agriculture biomass, lignocelluloly=c enzymes, biomass u=liza=on

IS08
SelecAon of promising hydrolyAc halotolerant producing bacteria in the seafood

fermentaAon technology
Maureen Kumaunang 1,2,*, Wasana Suyotha2, Suppasil Maneerat2
Chemistry Department, Faculty of MathemaPcs and Natural Sciences, Sam Ratulan-

gi University, Jalan Kampus Unsrat, Manado 95115, Indonesia
Biotechnology for Bioresource UPlizaPon Laboratory, Department of Industrial
Biotechnology, Faculty of Agro Industry, Prince of Songkla University, Hat Yai
90110, Thailand
E-mail: maureenkumaunang@unsrat.ac.id
Food fermentaPon is undeniably implemenPng a significant role in the food indus-

try today. Almost one-third of total food consumpPon worldwide is fermented
foods. However, mostly food fermentaPon was conducted in the tradiPonal meth-
od which will lead to quality variaPons of fermented food results. Most problems
arise in seafood fermentaPon are variaPon in the raw material and length of the
fermentaPon process. One method that can be applied to control those problems
is the applicaPon of starter culture. Before introducing the starter cultures, several
invesPgaPons such as technological properPes and safety a2ributes of the selected
microorganisms must be performed firstly. Certain technological properPes are
essenPal to make sure the starters have special characterisPcs for improving the
food quality. Safety a2ributes are obligatory to make sure that the starters are safe
to be applied in the food fermentaPon and for human consumpPon. Based on
these invesPgaPons, two promising starter candidates, selected from salted fer-
mented shrimp paste which having halostable proteolyPc and lipolyPc acPviPes
were carefully chosen and applied in the seafood fermentaPon.
Keywords: halotolerant, hydroly=c enzymes, safety alributes, seafood fermenta-

=on, starter cultures.
48
ABSTRACTS
ORAL PRESENTATION
OF ORAL PRESENTATIONS
OP01
Chemical Profiling of EssenAal Oil from Zanthoxylum acanthopodium Fruits and Its AnAdi-
abeAc Effect In Vitro and In Vivo
YanA1, Maria Anisa1, Katarina Hana Palupi JaA Savitri1, Vivitri Dewi Prasasty1, Soegianto
Ali2
1
Department of Biotechnology, Atma Jaya Catholic University of Indonesia, Jalan Jenderal
Sudirman 51, Jakarta 12930
2
Department of Medicine, Atma Jaya Catholic University of Indonesia, Jalan Pluit Raya 2,
Jakarta 14440
InflammaPon plays an important role in development of type 2 diabetes mellitus

(T2DM), including obesity-related insulin resistance. Biomarkers of inflammaPon, such as C-
reacPve protein (CRP), tumor necrosis factor alpha (TNF-a), interleukin-6, and monocyte
chemoa2ractant protein-1 (MCP-1) are present at increased concentraPons in insulin re-
sistant and obese individuals. The fruit of Zanthoxylum acanthopodium or lemon pepper is
locally known as andaliman and belongs to endemic spicy plant in Tapanuli region, North
Sumatera (Indonesia). Ripen Z. acanthopodium fruit has reddish-purple colour and the peri-
carp has strong lemon aroma due to its major essenPal oil contents. In this study, we invesP-
gated the chemical profiling of Zanthoxylum acanthopodium essenPal oil (ZAEO) and its
anPdiabePc potenPal through a2enuaPon of proteins related to diabetes in hepatocytes in
vitro and glucose level profile in diabePc mice induced by alloxan in vivo. ZAEO was extracted
from Z. acanthopodium fruits using hexane and idenPfied by using pyrolysis gas chromatog-
raphy-mass spectrometry (py-GC/MS). ZAEO was tested for its cytotoxicity against human
Chang liver cells as an in vitro cultured hepatocytes model. Effect of ZAEO (1-50 g/mL) on
protein expression related to T2DM, including CRP, TNF-a, and MCP-1 was quanPfied by
enzyme linked immunosorbent assay (ELISA) assay. ZAEO at 10 and 25 mg/kg body weight
was also given orally administraPon in alloxan-induced diabePc mice for 4 weeks, followed
by the measurement of blood glucose level. Chromatogram profile demonstrated that ZAEO
consisted of 69.03% of essenPal oil groups with major compounds of carveol, phytol, myrta-
nyl acetate, and citronellyl acetate. MTT profile showed that safest dose of ZAEO against
hepatocytes was reached up to 10 g/mL. ELISA data showed that among three proteins,
ZAEO exerted significant inhibitory effect against MCP-1 protein expression secreted by
hepatocytes. At lowest dose (1 g/mL), ZAEO a2enuated MCP-1 expression up to 30%, re-
specPvely. In vivo data demonstrated that ZAEO treatment at low dose (10 mg/kg body
weight) showed the significant suppressive effect on blood glucose level compared to that of
diabePc mice control. InteresPngly, both ZAEO and memormin showed the similar effect on
reducing the blood glucose level. These findings suggest that ZAEO may down-regulate in-
flammaPon related to T2DM through inhibiPng MCP-1 expression that lead to the increase
of insulin-sPmulated glucose uptake.
Keywords: Zanthoxylum acanthopodium fruits, essenPal oil, anPdiabePc effect, chemical
profiling, in vitro, in vivo
50
OP02
SYNTHESIS AND ACTIVITIES TEST OF CURCUMIN ANALOGUES DERIVATIVES AS

ANTI-MALARIAL AGENTS FROM VANILLIN
Bambang Purwono*1, Jakfar Abdussalam1, Rafian Azhar Abdul Rozak1
Department of Chemistry, Faculty of Maths. & ScienceUniversitas Gadjah Mada

Bulaksumur, Yogyakarta, Indonesia
Curcumin has been shown to possess many biological acPviPes including anPmalari-
al agents. In order to expand their potenPal as anPmalarials, a series of analogues
curcumin derivaPves were synthesized from vanillin and evaluated for their acPvi-
Pes using Hem PolymerizaPon InhibiPon Assay (HPIA). Three target compounds
have been synthesized from vanillin namely 2,6-bis(4-hydroxy-3-
methoxybenzylidene cyclohexa-1-one (1), 2,6-bis(5-bromo-4-hydroxy-3-
methoxybenzylidene cyclohexa-1-one (2) and 2,6-bis(4-hydroxy-3-methoxy-5-
morpholinobenzylidene cyclohexa-1-one (3). The acPviPes anPmalarials test using
HPIA method showed that most potent derivaPves compounds were 1, 2, and 3
with inhibiPon at IC50 of 19.85, 20.88 and 26.56 mM respecPvely. The analogue of
curcumin derivaPves exhibited lower anP-malarial potency against Chloroquine
(IC50 of 6.03 mM) but sPll promising candidates for the further design of novel anP-
malarial agents.
Keywords: an=malarial, curcumin, HPIA, Chloroquine
*Corresponding author:
E-mail address: purwono.bambang@ugm.ac.id
Phone number: +6285102967033
OP03
Secondary Metabolites From One of The Indonesian Medicinal Plants : Leaves of

Desmodium triquetrum Linn. (Fabaceae)
Elvira HermawaA*, Lia D. Juliawaty*, Kiyotaka Koyama, kaoru Kinoshita,

Kunio Takahashi and Euis H. Hakim*
*Natural Product Chemistry Laboratory, Department of Chemistry, Faculty of Mate-

ma=cs and Natural Sciences, Ins=tute of Technology Bandung, Jalan Ganesha 10,
Bandung 40132, Indonesia
Department of Pharmacognosy and Phytochemistry, Meiji Pharmaceu=cal

University, Noshio, 2-522-1, Kiyose-shi, Tokyo 204-8588, Japan
Desmodium (Fabaceae) is known as a genus of plant which is used as the component

of tradiPonal medicines for diurePc, anPinflammaPon, hemorrhoids, tonicum,
cough and anPmicrobial. This genus distributed all over Indonesia. Desmodium tri-
quetrum is one of species belonging to Desmodium genus which has not analyzed
yet for its chemical contents. In preliminary assay, the methanol extract of leaves of
D. triquetrum showed high acPvity on inhibiPon of tyrosine kinase assay with % inhi-
biPon was 59,4 % (100 µg/mL extract), and the same extract had high cytotoxic
acPvity againts murine leukemia P-388 cell with IC50 6,5 µg/mL. The secondary me-
tabolites isolated from those extract by using varians chromatography techniques
including vacuum liquid chromatography, radial chromatography, and gravity chor-
matography (sephadex LH-20) yielded three compounds and have been idenPfied as
epicathecin (1), kaempferol (2) and p-hydroxy benzoic acid (3). The stuctures of
those isolated compounds were determined according to spectroscopic data in-
cuding 1H NMR and 13C NMR. Cytotoxic evaluaPon of compounds 1 – 3 showed IC50,
24.7, >100, and 55.0 g/mL, respecPvely. One of the compound, p-hydroxy benzoic
acid (3) has been examined on tyrosine kinase inhibitor assay and is not acPve.
Keywords: Desmodium triquetrum, Fabaceae

52
OP04
DETERMINATION OF TOTAL PHENOLIC CONTENT
AND ANTIOXIDANT ACTIVITY FROM SEVERAL FRACTIONS
OF AREN’S (Arenga pinata) MIDRIB FLOUR
Meiske Sangi1, Julius Pontoh2, Yudhie Prasetyo3, Maureen Kumaunang4

1,2,3,4
Program Studi Kimia, FMIPA Universitas Sam Ratulangi
E-mail: meiskesangi@gmail.com
Tel. 081356489533
Aren (Arenga pinnata) is a type of plant widely used by Indonesian people as a

source of food and tradiPonal medicine. Aren’s midrib flour as a part of aren plant is
commonly used by the people to eliminate itching and skin burned. The aims of this
study were to determine the total phenolic content and anPoxidant acPvity of some
fracPons of aren’s midrib flour extract. MaceraPon with ethanol was applied as the
extracPon method followed by parPPon with several solvents such as petroleum
ether, ethyl acetate, ethanol and aquades. AnPoxidant acPvity was determined by
DPPH (1,1-diphenyl-2-picrylhydrazyl) radical capture method using UV-Vis
spectrophotometer at a maximum absorpPon of 517 nm. The results showed that
ethyl acetate fracPon gave the highest total phenolic content of 172.857 mg/kg,
followed by ethanol fracPon of 107.449 mg/kg, petroleum ether fracPon of 91.531
mg/kg, and water fracPon of 29.388 mg/kg, respecPvely. The highest anPoxidant
acPvity was also found in ethyl acetate fracPon with IC50 value was 90.573 g/mL,
followed by ethanol extract 128.825 g/mL, petroleum ether fracPon 138.676 g/
mL and water fracPon 217.270 g/mL, respecPvely. Based on all results, it can be
concluded that ethyl acetate could be applied as the good parPPon solvent to ex-
tract the phenolic compound in aren’s midrib flour.
Keywords: Aren’s midrib flour, total phenolic content, an=oxidant ac=vity, DPPH
OP05
Phytochemicals Content and AnAoxidant AcAvity of Some TradiAonal Medicinal
Plants
of Sangihe Ethnics in North Sulawesi Province
Max R.J Runtuwene1,*), Vanda S Kamu1), Paulina Veronika Y Yamlean2), dan Ratna
Siahaan3)
1)
Chemistry Department, Faculty of MathemaPcs and Natural Sciences, Sam Ratu-
langi University
2)
Pharmacy Department, Faculty of MathemaPcs and Natural Sciences, Sam Ratu-
langi University
3)
Biology Department, Faculty of MathemaPcs and Natural Sciences, Sam Ratulangi
University
*Corresponding author: runtuwenemrj@unsrat.ac.id
The Sangihe ethnic group in North Sulawesi province has local wisdom in uPlizing
plants to treat various diseases. However, scienPfic informaPon about these plants
are sPll limited. In this study, various aspects of these plants such as phytochemical
content and biological acPvity were invesPgated. Firstly, the extracPon step was
applied by maceraPon method using the methanol solvent. Subsequently, each of
the resulPng extracts was invesPgated for their phytochemicals content and anPoxi-
dant acPvity. Phytochemicals content were determined using convenPonal chemical
methods including precipitaPon and color reagents. AnPoxidant acPvity was deter-
mined using diphenyl-picrylhydrazyl (DPPH) method. The results indicated that all
medicinal plants contain various secondary metabolites such as alkaloids, flavo-
noids, glycosides, phenols, saponins, and sterols. In addiPon, some plants exhibit
high anPoxidant acPvity. As a conclusion, all results should be invesPgated further
for the ethnomedicinal and pharmacological purposes of those medicinal plants.
Keywords: Sangihe ethnics, medicinal plants, an=oxidant ac=vity, phytochemicals

content
54
OP06
GC/MS IdenAficaAon of Tempeh Oil and Its AnAphotoaging Effect in UVB-induced
Photoaging Mice
Dionysius Subali, YanA, and Bibiana WidiaA Lay
Master of Science in Biotechnology Program, Faculty of Biotechnology, Atma Jaya

Catholic University of Indonesia, Jalan Jenderal Sudirman 51, Jakarta 12930, Indo-
nesia
Polyunsaturated fa2y acid (PUFA) is one of the substances that are consid-
ered could prevent skin photoaging. TradiPonal fermented food, especially tempeh
could be the best source for PUFA to replace animal PUFA from fish and nuts. Here,
we determined the effecPveness of tempeh oil extracted from white and black
soybean on reducing skin photoaging in UVB-induced photoaging mice through
down-regulaPng the gene expression related to pro-inflammatory enzymes and
cytokines by qRT-PCR analysis. Tempeh oil was also idenPfied for its chemical com-
ponents by gas chromatography mass spectrometry (GC/MS). For in vivo study, a
total of 28 male mice aged 6 weeks were divided into 7 group, posiPve control (K+),
negaPve control (K-), standard omega 3 (SO), black soybean tempeh oil 100 mg/kg
body weight (HO100), black soybean tempeh oil 300 mg/kg body weight (HO300),
white soybean tempeh oil 100 mg/kg body weight (PO100), and white soybean
tempeh oil 300 mg/kg weight (PO300). The dorsal areas of the mice were shaved to
give hairless condiPon. UVB radiaPon was given incrementally. Histopathology ex-
aminaPon and gene expression analysis were done from skin sample. GC/MS profil-
ing demonstrated that tempeh oil extracted from white and black soybean tempeh
had high contents of PUFA in parPcular linoleic acids (52.3% and 85.69% in white
and black soybean tempeh oil). Histopathology profile revealed that tempeh oil
treatment affected the mice skin repair through epidermal atrophy by epidermis
thinning and proliferaPon of hair follicles. Both tempeh oil (HO300 and PO300)
effecPvely down-regulated the gene expression of MMP-1, MMP-3, MMP-9, COX-
2, and iNOS in UVB-induced photoaging mice. These data indicate that both white
and black soybean tempeh oil may offer a promising natural cosmeceuPcal candi-
date for treatment of skin photoaging caused by UVB exposure.
Keywords: Tempeh oil, white and black soybean tempeh, anP-photoaging effect,
mice photoaging, UVB, in vivo
OP07
DEVELOPMENT OF BASIC CHEMICAL MODULE OF THERMOCHEMICAL MATERIAL
WITH STEM PROBLEM- BASED LEARNING APPROACH FOR STUDY PROGRAM OF
CHEMICAL EDUCATION STUDENTS
Effendi1, Tatang Suhery2, AgusAn KurniaA3,

1, 2, 3
Faculty of Teacher Trainerand EducaPon of Sriwijaya University
E-mail: effendi@…ip.unsri.ac.id
Abstract: The purpose of this study is to produce the chemical modules of

Thermochemical STEM Problem-Based Learning approach that meets the valid and
pracPcal criteria. The development model used is the ADDIE development
model.ADDIE development model consists of three phases consisPng of analysis,
design, development, implementaPon, and evaluaPon. In this study, evaluaPon
phase combined with formaPve evaluaPon Tessmer consisPng of self-evaluaPon,
expert review, one-to-one, small group, and a field test. The result of pedagogical
validaPon test get 0,67 value and design get 1 value then material get 1 value. So
for average expert review is 0,89 with the very decent category. The average test
results pracPcality in stage one to one is 0.66 which is included in the medium
category. Then, at the phase of a small group gain increased value from the
previous phase, which is 0.88 with a high pracPcality category. Based on the results
of research conducted showed that modules with STEM PBL approach have met
the valid and pracPcal criteria. For faculty and students make sure to use the
Thermochemical Basic Chemistry I module with STEM PBL approach as a teaching
material.
Keywords: development research, basic chemical module, thermochemical, ADDIE
56
OP08
ReconstrucAon of Basic Chemistry Modul Based on Brainstorming Interac(ve

(BRAIN) to Enhance High Order Thinking Problem Solving Papua Chemical Edu-
caAon Students Papua.
Florida Doloksaribu, 1Irwandi Yogo Suaka 2, Frans A.Kafiar

FKIP-Prodi Pendidikan Kimia Universitas
email: floridadolok@gmail.com
This study aims to obtain a module that can be used to improve the thinking skills
of primary college of chemistry educaPon at Cenderawasih University, based on
brainstorming interacPve (BRAIN). This module is devoted to the field of basic
chemistry part one. The development is based on the indicator thinking of
problem solving include to material content of chemistry part one. Design
of modul based reconstrucPon model educaPon (MER). The characterisPcs of this
module are: (1) developed according to the needs and competencies aspects of
the objecPves and funcPons of the curriculum, (2) the material context is adapted
to the needs of Papuan students based on local wisdom, (3) the material content
is adjusted to the cogniPve level of the chemistry part one, (4) the contents of the
module are prepared based on material reconstrucPon from discourse analysis,
subject ma2er clarificaPon, refinement, composite material with thinking, revision
and validaPon of the team. Based on expert validaPon with validaPon model of
exvert judgmentet, known legibility and material conformity 85.3%, accuracy of
illustraPon and picture 90.1%, and accuracy of task and exercise 87.7%. This indi-
cates that the material and thinking instrucPonal module is valid and feasible to
use.
Key words: Module, brainstorming interac=ve, problem solving thinking

OP09
SYNTHESIS OF O-CARBOXYMETHYL N-PALMITOIL CHITOSAN WHICH USEFUL AS
AN EDIBLE COATING FILM THROUGH INTERESTERIFICATION AND AMIDATION
REACTIONS FROM FATTY ACID
DANIEL*, EVA MARLIANA and YOLANDA V. A. S

Department of Chemistry, Faculty of MatemaPcs and Natural Sciences
Mulawarman University, Indonesia
*E-mail of Corresponding Author: daniel_trg08@yahoo.com
The aim of this research was to synthesize an edible coaPng film named O-
Carboxymethyl N-Palmitoil Chitosan. This film was synthesized through amidaPon
between O-Carboxymethyl Chitosan and Methyl Palmitat. O-Carboxymethyl
Chitosan was prepared from esterificaPon of Aldimine Chitosan and monochloro
acetate acid. Amine subsPtuent at chitosan was protected by converPng
acetaldehyde to aldimine chitosan and followed by deprotecPon by using sodium
carbonate. A|erward, O-Carboxymethyl N-Palmitoil Chitosan was formed as
CoaPng Film using acePc acid 1% which useful as an edible coaPng film. The FT-IR
analysis of O-Carboxymethyl N-Palmitoil Chitosan showed that vibraPon peak at
3466.08 cm-1 indicated –OH vibraPon that overlap with –NH amide. Wavenumber
at 1689.64 cm-1 displayed C=O amide subsPtuent and carboxylic acid that overlap.
Wavenumber at 1562.34 cm-1 exhibited the presence of -NH amide vibraPon, while
wavenumbers at 2920.23 cm-1, 2850.79 cm-1, and 1463.97 cm-1 indicated the –CH
vibraPon which supported by (CH2)n vibraPon at wavenumber of 719.45 cm-1.
Wavenumber at 1072.35 cm-1 indicated C-O-C subsPtent from caboxymethyl ester.
The HLB value of O-Carboxymethyl N-Palmitoil Chitosan is 11.7 which can be
categorized as o/w emulsifier. Based on DTA Termogram, it showed the exothermic
thermal degradaPon temperature is 440oC for coaPng film, while SEM analysis
displayed the changing in the surface of O-Carboxymethyl N-Palmitoil Chitosan. In
addiPon, film tensile test showed that the value of film tensile is 0.02 Kgf. Microbio-
logical tesPng of coaPng film displayed the anPbacterial acPvity with LC50 value of
3738.47 ppm.
Key words: Chitosan, O-Carboxymethyl N-Palmitoil Chitosan,

AmidaPon, EstericaPon, CoaPng Film, Surfactant
58
OP10
THE EFFECTS OF PROBLEM-BASED LEARNING METHOD ON STUDENTS’ LEARNING
INDEPENDENCE OF CHEMISTRY LEARNING IN HIGH SCHOOL
Suyanta1), Endang W. Laksono1), Novia Fitri Fadhilah2), and Ihwan Rizky2)

Email: suyanta@uny.ac.id
1)
Chemistry EducaPon Yogyakarta State University
2)
Chemistry EducaPon Study Program, Graduate School, Yogyakarta State University
Chemistry learning in high school that trains and develops students' self-sufficiency
and independence has not been done opPmally because learners sPll depend on
gejng informaPon and knowledge from teachers. Problem-based learning method
used in the teaching and learning process is expected to facilitate students' with self
-reliance and learning independence. This method is a problem-oriented learning
method that makes students be accustomed to solving problems in order to train
their ability in discoveringa concept in the learning process. Teaching learning pro-
cess with PBL model is done for the subject ma2er of acid & base soluPon and elec-
trolyte & non electrolyte soluPon. Learning independence assessed in this study
were self-management, moPvaPon, and confidence. The data of the study were in
the form of descripPve quanPtaPve data and analyzed using Anava / Anacova test.
The research findings showed that there was a difference of students’ learning inde-
pendence through the applicaPon of problem-based learning method and control
method in teaching and learning process.
Keywords: problem-based learning method, learning independence

OP11
INCREASING THE STUDENTS' CRITICAL THINKING SKILLS THROUGH VOLTAIC CELL

LABORATORY ACTIVITIES BASED ON THEIR MENTAL MODEL
A AlbaiA1), S Liliasari2), O Sumarna2) and M A Martoprawiro3)

1
Universitas Cenderawasih, Abepura-Sentani Street, Jayapura, Indonesia
2
Universitas Pendidikan Indonesia, Dr. SePabudi Street No. 229, Bandung 40154,
Indonesia
3
InsPtut Teknologi Bandung, Ganesha Street No. 10, Bandung 40132, Indonesia
Corresponding author: e-mail : albaiA@tip.uncen.ac.id
Phone number: +6281344404937
CriPcal thinking skills (CTS) become a very important skills consideraPon among oth-
er transferable skills in order to succeed facing dynamic and complex world. The
purpose of this study was to improve the students’ CTS through voltaic cell laborato-
ry acPviPes based on their mental models. It was a mixed methods embedded ex-
perimental model research design. The study involved 15 students who took Physi-
cal Chemistry Laboratory courses, one of university in Papua. Essay test of 5 items
was used to analyze their CTS that calculated by N-Gains value. Each items was de-
signed to interconnect macroscopic, sub-microscopic, and symbolic levels. Then N-
Gain Kruskal-Wallis test have been done between CTS descriptors. Students induced
and considered inducPon descriptor was the highest students mastery meanwhile
other descriptors were the same (no one reached the lowest mastery). It is neces-
sary to integrate physical chemistry laboratory and physical chemistry lecture for
increasing the students’ CTS.
Keywords: cri=cal thinking skills, mental model, physical chemistry laboratory,

voltaic cell
60
OP12
The Effect Of CooperaAve Learning Model Type Review Course Hooray (CRH)
And Jigsaw MoAvaAon and Learning Outcomes in the Redox Materials Subject
on Chemistry EducaAon Tadulako University
Dr. Kasmudin Mustapa, S.Pd.,M.Pd

Department of MathemaPcs and Natural Sciences
EducaPon Faculty of Teacher Training and EducaPon
Universitas Tadulako, Palu, Indonesia
kasmudin…ipuntad@gmail.com
This study aimed to determine the effect of cooperaPve learning model Type
Review Course Hooray (CRH) And Jigsaw towards the collage students moPva-
Pon and learning outcomes in the Redox Materials Subject on Chemistry Educa-
Pon Tadulako University. This research was a pre-experimental with the staPc
pretest-pos2est group design. The samples used in the study were students A
(n=40) as a class experiment 1 and students B (n=38) as a experiment 2. The
results of data analysis, the average value of class experiment 1 ( ) was 88.4
and the experimental class 2 ( ) was 83.12. Results of hypotheses tesPng by

staPsPcal t-test two parPes it was obtained -ttable ≤tcoll≥ + ttable (tcoll = 46,27 for
class experiment 1 ; tcoll = 34.50 for class experiment 2 and ttable = 1.78) with a
significance level a = 0.05 and degrees of freedom 56, then H0 was rejected and
Ha was accepted. The results of the students learning moPvaPon quesPonnaire
showed that the experimental class 1 was the ajtude of "strong agree" with the
posiPve category 80,10% and the experimental class 2 was in the ajtude of
"agree" with the posiPve category 81.15%. It can be concluded that there is
influence of cooperaPve learning model Type Review Course Hooray (CRH) And
Jigsaw to the students moPvaPon and learning outcomes Chemistry EducaPon
study program on the Redox Materials Subject on Chemistry EducaPon Tadulako
University.
Keywords:, type review course hooray, Jigsaw, mo=va=on, learning outcomes,

OP13
Phytochemical Screening and AnAoxidant AcAvity of Methanolic Extract of Ara-

bica Roasted Coffee Beans from Wamena and Moanemani
SepAani Mangiwa1), Agnes Eri Maryuni2)
Department of Chemistry, Faculty of MathemaPcs and Natural Science,

Cenderawasih University, Jayapura, Papua 1,2)
Email : septhy.mangiwa@yahoo.com1)
Coffee beans contain a variety of secondary metabolite compounds that are be-
lieved to have various biological acPviPes, one of which is as an anPoxidant. AnP-
oxidant compounds can counteract free radicals and reduce the risk of some dis-
eases. The aims of this study were to determine phytochemical content and anP-
oxidant acPvity of methanolic extract of Arabica roasted coffee beans from Wame-
na and Moanemani. The extracPon was performed by maceraPon method using
methanol as a solvent for 24 hours. Phytochemical screening was carried out using
standard methods. QualitaPve analysis of anPoxidant acPvity was performed by
DPPH method and quanPtaPve analysis was determined by Spectrophotometer Uv
-Vis at 517 nm wavelength. The result showed that methanolic extract of Arabica
coffee beans from Wamena and Moanemani contain of alkaloid, flavonoid, torpe-
doed, siphoning and tannin. Both of extracts have anPoxidant acPvity and can in-
hibit free radical 61,71 and 69, 7 % with IC50 value about 107,97 and 100,91 ppm,
respecPvely. In conclusion, the methanolic extract of Arabica roasted coffee beans
from Wamena and Moanemani can be used as source of natural anPoxidant.
Keywords : Arabica roasted coffee beans, phytochemical, an=oxidant, DPPH meth-

od
62
OP14
Cytotoxic Limonoids from The Stembark of Chisocheton pentandrus (Meliaceae)
Supriatno1, Wiro Naibaho1, Nurlelasari1, Desi HarneA1, Ace Tatang Hidayat1,2,

Ronny Lesmana2,3, Unang Supratman1,2*, Mohamad Nurul Azmi4, and Yoshihito
Shiono5.
1
Department of Chemistry, Faculty of MathemaPcs and Natural Sciences,
Universitas Padjadjaran, JaPnangor 45363, Indonesia.
2
Central Laboratory, Universitas Padjadjaran, JaPnangor 45363, Indonesia.
3
Department of Phisiology Medicine, Faculty of medicine, Universitas Padjadjaran,
JaPnangor 45363, Indonesia.
4
School of Chemical Sciences, Sains Malaysia UniversiP, Minden 11800, Penang,
Malaysia.
5
Department of Food, Life, and Environmental Science, Faculty of Agriculture,
Yamagata University, Tsuruoka, Yamagata 997-8555, Japan.
Corresponding authors. E-mail: unang.supratman@unpad.ac.id
Six limonoids, pentandricine (1), ceramicine B (2), 6-de(acetyloxy)-23-

oxochisocheton (3), 6-de(acetyloxy)-23-oxo-7-O-deacetylchisocheton (4),
dysobinin (5) and epoxyazadirone (6) were isolated from the stembark of
Chisocheton pentandrus through of combinaPon of column chomatography on silica
gel. The chemical structure were idenPfied based on spectroscopic evidences and
by comparison to those spectra data previously reported. These compounds were
isolated from this plant for the first Pme. Epoxyazadirone (6), showed strongest
cytotoxic acPvity against MCF-7 breast cancer cells with IC50 values of 9.12 µM.
Keywords: Chisocheton pentandrus, limonoid, Meliaceae, MCF-7.

OP15
TransesterificaAon of Used Cooking Oil into Biodiesel Using NaN3/Modified Clay
Catalyst
Ilham Salim1 , Alex A. Lepa2 , Frans P. Kafiar3

1)
Department of Chemistry, Faculty of Science and MathemaPcs, Cenderawasih
University, Jl.Kamp Wolker Kampus Baru Waena Jayapura, Indonesia. Email:
ilhamkimia@yahoo.com
2)
Department of Chemistry EducaPon, Faculty of Teacher Training and EducaPon,
Cenderawasih University, Jl.Raya Sentani Abepura, Jayapura, Indonesia
Email: lepa_alex@yahoo.com
3)
Department of Chemistry EducaPon, Faculty of Teacher Training and EducaPon,
Cenderawasih University, Jl.Raya Sentani Abepura, Indonesia Jayapura, Indonesia
Email: franspither@gmail.com
TransesterificaPon of used cooking oil into biodiesel has been done using NaN3/
modified clay catalyst.The Ni/modified clay catalyst was synthesized by destrucPng
the Merauke clay with 8M HCl soluPon, then NaOH pellet (NaOH/clay raPo = 0.8),
followed by treaPng with AlCl3.6H2O, CTAB and disPlled water. Then the mixture
was regulated to pH of 11.5. Next, the mixture was then poured into a reactor for
hydrothermal process at 140 oC for 72 h. The results of the dealuminaPon of clay
was characterized by X-ray Fluorescence and the synthesized zeolite was character-
ized using X-Ray DiffracPon, surface area analyzer and Scanning Electron Microsco-
py. The synthesized zeolite was impregnated by NaN3 soluPon as a precussor pro-
duced the NaN3/modified clay sample. The transesterificaPon of used cooking oil
process was carried out in the temperature of 65oC and reacPon Pme of 6h. rasio of
catalyst : used cooking oil : methanol was 1.0 : 20.0 : 13.3. The main liquid product
of transesterifikaPon was methyl ester and it was analyzed using Gas Chromatog-
raphy Mass Spectrometer. The resulted showed that the dealuminaPon of clay
had Si content of 34.77 % and Al content of 5.67 %. The results of measurements
with XRD produced a different form of chromatogram and type of zeolite. The
results of transesterificaPon used cooking oil into biodiesel using NaN3/modified
clay catalyst was 91.5 wt %, meanwhile transesterificaPon used cooking oil into
biodiesel using modified clay catalyst was 85 wt % at the same of treatment.
Keywords: clay, modified, zeolite, transesterifica=on, used cooking oil, biodiesel

64
OP6
Synthesis of Silver NanoparAcles using Leaf Extract of Medicinal Plants and Analy-
sis of AnAmicrobial AcAvity.
Henry F. Aritonang
Plant-mediated synthesis of nanomaterials has been increasingly gaining popularity

due to its eco-friendly nature and cost-effecPveness. In the present study, we syn-
thesized silver (Ag) nanoparPcles by using medicinal plant from an aqueous soluPon
of Lantana Camara and Impa=ens Balsamina leaf extract as a bioreducing agent.
This method allowed the synthesis of nanoparPcles, which was confirmed by UV-Vis
and TEM. UV–Vis spectra of Ag nanoparPcles and visual percepPon of brownish yel-
low color from colorless reacPon mixture confirmed the Ag nanoparPcles formaPon.
AddiPonally, TEM study confirmed that AgCl soluPons for all concentraPons have
produced Ag nanoparPcles. Moreover, L. Camara and I. Balsamina leaf extract were
separately tested to examine their anPmicrobial acPviPes. The acPviPes were tested
against Gram-posiPve Staphylococcus aureus (S. aureus) and Gram-negaPve Esche-
richia coli (E. coli). The Ag nanoparPcles synthesized from leaf extract of L. Camara
shows highest anPbacterial acPvity was observed against growth of bacteria spe-
cies.
Keywords: Medicinal plant; leaf extract; an=bacterial ac=vity

OP17
The effect of ReacAon Time of Hydrothermal Process on ModificaAon of
Natural Zeolite to Zeolite with RaAo of Si/Al = 1
Alex A.Lepa1, Ilham Salim2 , Frans P. Kafiar3

1)
Department of Chemistry Educa=on , Faculty of Teacher Training and Educa=on,
Cenderawasih University,Jayapura ,Indonesia
Email : lepa_alex@yahoo.com
2)
Department of Chemistry Faculty of Science and Mathema=cs, Cenderawasih Uni-
versity , Jayapura,Indonesia
Email :ilhamkimia@yahoo.com
3)
Department of Chemistry Educa=on , Faculty of Teacher Training and Educa=on,
Cenderawasih University,Jayapura ,Indonesia
Email : franspither@gmail.com
ModificaPon of natural zeolite to zeolite with Si/Al = 1 raPo has been done. Natu-
ral zeolite is generally found in the form of the zeolite mineral blend systems with
other types of zeolites, amorphous minerals such as feldspar, silica, alumina, transi-
Pon metal oxides, and organic contaminants called heterogeneous composiPon. In
order to funcPon properly as catalyst or adsorbent, it needs to be modified into
zeolite which is more homogeneous. The modified natural zeolite was synthesized
by destrucPng the Klaten natural zeolite with 6M HCl soluPon. A|er drying at 120
o
C for 4 h, then followed by treaPng with AlCl3.6H2O, NaOH, CTAB and disPlled
water. The mixture was regulated to pH of 11.5. and The mixture poured into a
reactor for hydrothermal process at 140 oC. The reacted hydrothermal process was
carried out in the variaPon of reacPon Pme of 24, 48, and 72 h. Then dried in the
oven for 4 h at 120 °C, and calcined in furnace at 350 oC for 3 h. The synthesized
zeolite was characterized using FTIR (Fourier Transform Infra Red), XRD (X-Ray
DiffracPon), surface area analyzer. The resulted showed that analysing by XRD
were new minerals formed and crystallinity increased.. Analysis of pore size used
BET method, the porosity and surface area increased.
Keywords: Natural zeolite, modifica=on, heterogeneous, homogeneous,

hydrothermal
66
OP18
PVA/CHITOSAN-MONTMORILLONITE COMPOSITE FOR FUEL CELL APPLICATION :
THERMAL AND PHYSICAL PROPERTIES ON SPECIFIC BALANCE
Lukman Atmaja1,*, Zuhdan Ali Robba1
1
Department of Chemistry, Faculty of Science, Ins=tut Teknologi Sepuluh Nopember,
Surabaya 60111, Indonesia
*Corresponding author : lukman_at@chem.its.ac.id, phone : 00-62-31-5943353
Composite synthesis involving a combinaPon of organic and inorganic materials is

the main route for the search for materials for fuel cell membranes. In accordance
with this, PVA/Chitosan-Montmorillonite membrane fabricaPon has been carried
out with sulfuric crosslinking. PVA/Chitosan (3: 1) blend was varied with
montmorillonite loading of 1, 2, 4, 6 and 8% and the resulPng membranes were
characterized by FTIR for funcPonal group confirmaPon, TGA for thermal properPes
and tensile tests for mechanical properPes. Membranes with 2% montmorillonite
show the best thermal stability with temperatures up to 230 0C and the best
mechanical properPes with modulus of elasPcity reaching 172.2 MPa. Under these
condiPons, the membrane will be in accordance with the requirements of
mechanical and physical properPes for the Direct Methanol Fuel Cell applicaPon.
Key words : Chitosan, Montmorillonite, PVA, Membrane, DMFC

OP19
PERFORMANCE OF GRAPHITE/GRAPHENE, MANGANESE (Mn)/ GRAPHITE AND
Mn/ GRAPHENE AS ELECTRODE
ON ANODE OF PRIMARY BATTERY
Rikson Asman FerAles Siburian1*, Andri Hassan Simbolon1, Minto Supeno1, Herlince
Sihotang1, Nurhaida Pasaribu1, Saur Lumban Raja1, Dewi RaPh1, CrisPna Simanjuntak1
1
Chemistry Department- Universitas Sumatera Utara, Medan-Indonesia
Jalan Bioteknologi No. 01 Kampus USU Medan 20155
*)Email : riksonsiburian2000@yahoo.com
Research about properPes electrode of Graphite/Graphene, Manganese (Mn)/

Graphite and Manganese (Mn)/Graphene on anode of primary ba2ery was carry
out. The purposes of this research are to generate electrode on anode of primary
ba2ery and to compare electrical conducPvity primary ba2ery anode with elec-
trode Graphite/Graphene, Manganese (Mn)/Graphite and Manganese (Mn)/
Graphene as electrode on anode ba2ery primary, respecPvely this reserch uses
modified hummer method and impregnaPon mothod to produce Graphene and
Graphite/Graphene, Manganese (Mn)/Graphite and Manganese (Mn)/Graphene
electrodes respecPvely. The result show that the weak and broad peaks appear at
2θ (26o) for Graphene, indicaPng Graphene is formed (XRD data). While the sharp
peak appears at (31o) for the Manganese (Mn)/Graphene, indicaPng Mn is well
deposited on graphene. The XRD data is consitend with SEM-EDX data. The SEM-
EDX data Image of Graphene show that its surface is thin and flat. For Manganese
(Mn)/Graphene the blacks parPcles appear on Graphene, supposing Mn is
deposited on Graphene it is Confirmed by EDX data. The conducPfity data of
Graphene and Manganese (Mn)/Graphene are also well confirm the XRD and SEM-
EDX data. ConducPvity of Graphene 130 µS/Cm is highest among Graphite 80 µS/
Cm and anode primary ba2ery 10 µS/Cm (as a reference). The conducPvity of
Manganese (Mn)/Graphene 1250 µS/Cm is also highest among Manganese (Mn)/
Graphite 940 µS/Cm and Graphite/Graphene 100µS/Cm. All of data indicate that
Graphene and Manganese (Mn)/Graphene are potenPally to use a candidate
material for anode of primary ba2ery.
Keywords : Primary Balery’s Anode, Graphene, Graphite/ Graphene, Manga-

nese (Mn)/Graphite, Manganese (Mn)/Graphene.
68
OP20
AcAvated Carbon to improve glucose producAon from Switchgrass.
Yane Oktovina Ansanay

Geophysics Department, Faculty of MathemaPcs and Natural Sciences
Cenderawasih University.
AcPvated carbon is widely used in industrial for various applicaPons such as purifi-
caPon medium and catalyst to improve the chemical process reacPon in the pro-
ducPon of sugars. In this study the effecPveness and efficiently of carbon being
modified into acPvated carbon as a solid catalyst has observed to opPmize the pro-
ducPon of glucose from switchgrass. The size of acPvated carbon was made into 1-
1.5 mm by impregnated carbon into concentrated sulfuric acid.
The finding obtained the highest glucose producPon of 54.71% and this acPvated
carbon was able to be used for three Pmes. Hence, the idea of uPlizing solid cata-
lyst for reuse in the process was supported through finding in this research.
Keywords : ac=vated carbon, switchgrass, glucose, reuse.

OP21
Synthesis and CharacterizaAon of AcAvated Carbon from Sago Waste
(Metroxylon sagu) with ZnCl2 AcAvaAon And HNO3 ModificaAon.
YanA Kiding Allo, Sudarmono, Octolia Togibasa*)
Department of Physics, Faculty of Mathema=c and Natural Sciences,

Cenderawasih University
Jl. Kamp Wolker, Kampus Uncen Baru, Jayapura, 99358, Indonesia
*)
corresponding author: octolia@gmail.com
Previous researches have proved that acPvated carbon could be made from
various raw material which contains lignocellulose such as cane dregs and pine
waste. The aim of this research were to synthesis and characterize acPvated
carbon from sago waste due to its ligocellulose content. The synthesis process
was conducted through following stages: dehidraPon, carbonizaPon, silica
extracPon with NaOH, acPvaPon with ZnCl2 10%, and surface modificaPon with
HNO3 65%, successively. The chemical composiPon acquired from X-ray
fluoroscence confirmed that silica content in carbon from sago waste has
disappeared a|er silica extracPon with NaOH. The X-ray diffracPon pa2erns
showed that samples before modificaPon stage have amorphous acPvated cabon
while samples a|er modificaPon stages started forming exfoliated graphite
crystal, as shown from peaks at 2 30,27 and 35,1 . Finally, the infrared
spectra from both acPvaPon and modificaPon stages confirmed that the presence
of oxygen-containing groups has been increased.
Keywords: sago waste, ac=vated carbon, ac=va=on with ZnCl2, surface

modifica=on with HNO3
70
OP22
PreparaAon of metal (Ni,Co)Mo on SupporAng material Indonesian

natural zeolite
Gesyth MuPara Hikhmah Al Ichsan1 , Khoirina Dwi NugrahaningPyas2, a), Dian

Maruto Widjonarko2, Fitria RahmawaP2 and Witri Wahyu Lestari2
1
Department of Chemistry, Faculty of Postgraduate Sebelas Maret University
Jl. Ir. A. Sutami 36A, Ken=ngan, Surakarta 57126, Indonesia
2
Department of Chemistry, Sebelas maret University
Jl. Ir. A. Sutami 36A, Ken=ngan, Surakarta 57126, Indonesia
a)
email: khoirina@mipa.uns.ac.id
This research aims to prepare and characterize catalysts NiMo/NZ and CoMo/NZ.
The bimetallic catalysts NiMo/NZ and CoMo/NZ were prepared by coimpregnaPon
method. AcPvaPon of the catalysts included calcinaPon and reducPon. The
minerals present in the catalyst was analyzed using X-Ray Fluorescence (XRF),
funcPonal groups was characterized using Fourier Transform Infra Red (FTIR),
crystallinity was characterized using X-Ray diffrac=on (XRD) and morphology was
characterized using Scanning Electron Microscope (SEM). The result based on
characterizaPon, it is know that catalyst CoMo/NZ shows best amount metal
impregnated (Co metal content is 3,90 % and Mo metal content 8,88%). The CoMo/
NZ metal parPcels contained of CoO, MoO3 and NiMo/NZ metal parPcles contained
of NiO, MoO3.. Ni, Co and Mo metals on the surface had significant influnce on the
crystal structure and morphology accrording to XRD analysis. Base on
characterizaPon of the crystal stucture and the metal content it ist known that the
CoMo/NZ was the best sample compared to NiMo/NZ.
Keywords: natural zeolite, bimetallic catalyst, coimpregna=on, characteriza=on

OP23
PreparaAon and Morphological Property of Co3O4/ BaxSr1-xCo0.8Fe0.2O3-δ (x=0.5-0.7)
Composite Membranes using Starch as Binder Agent
Wahyu Prasetyo Utomo1, Aras Suci WijayanA1, Sillvana Nurherdiana1, Rendy Mu-
hammad Iqbal1, Hamzah Fansuri1*
1
Department of Chemistry, Ins=tut Teknologi Sepuluh Nopember, Surabaya, Indone-
sia
*Corresponding author: h.fansuri@chem.its.ac.id
Ba0.5Sr0.5Co0.8Fe0.2O3-δ (x=0.5-0.7) or BSCF was known as promising material to pre-

pare MIEC membrane for oxygen separaPon. Several modificaPons have been per-
formed to improve catalyPc acPvity of BSCF membranes. One of the promising tech-
nique was coaPng of the membrane with catalyst layer such as Co3O4. This work
invesPgates the simple and effecPve method to coat Co3O4 layer on the surface of
BaxSr1-x Co0.8Fe0.2O3-δ \ disc membranes resulPng Co3O4/BSCF composite membranes.
BSCF were prepared using iniPal powders by dry pressing method followed by sin-
tering at 1150 °C for 4 hours. The resulted BSCF dense membranes were coated
with Co3O4 using starch as binder agent in the form of suspension. The coaPng sus-
pension consist of 62.5% w/w of starch and 37.5% Co3O4. The coaPng suspension
was directly coated on the surface of the BSCF dense membranes followed by firing
at 800 °C for 3 hours. The surface morphology and cross secPon of the composite
membranes were observed using Scanning Electron Microscope (SEM) equipped
with Energy Dispersive X-ray (EDX). SEM images show that the method succeed to
coat Co3O4 layer on the surface of BSCF membranes. However, the distribuPon of
the Co3O4 was not uniform. The presence of Co3O4 layer was also indicated by the
increasing of Co intensity in the surface of membranes as analyzed by EDX.
Key words: BSCF membranes, Co3O4, composite membranes, coa=ng method,

starch.
72
OP24
ANODIC STRIPPING VOLTAMMETRY FOR DETERMINATION OF LEAD (Pb) IN POK
CHOI VEGETABLE
IrdhawaP1, Emmy Sahara1, RosanP Suryani Tince Mbatu1
1Department of Chemistry, Faculty of Mathema=c and Natural Sciences, Udayana

University, Kampus Bukit Jimbaran Bali 80361 Indonesia
Indonesia has a lot of kind of vegetables, including pok choi which is planted in Bed-
ugul Bali. Due to increase the yield of vegetable, the farmers use chemicals as fungi-
cide, ferPlizers and pesPcides. Pok choi can be contaminated by heavy metals
through absorpPon in metabolism process. The objecPve of this study is to validate
measurements and determine the concentraPon of lead (Pb) in whole pak choi us-
ing anodic stripping voltammetry. Measurements process used electrochemical
detecPon with three electrodes system, namely plaPnum disk as working electrode,
plaPnum wire/coil as counter electrode, and Ag/AgCl as reference electrode. The
results showed the opPmum of deposiPon Pme at 40 seconds, scan rate at 7.5 mV s
-1, and deposiPon potenPal at -0.53 mV. Linear range concentraPon, limit of detec-
Pon, and recovery measurements were obtained between 250 to 1500 ppb, 79 ppb,
and 98,99% 0,13%, respecPvely. Horwitz raPo was less than 2.0 for repeatability
ten Pmes measurements. Although the farmers used chemicals contain Pb, the re-
sult showed the level of Pb was 0.44± 0.19 ppm, not more than acceptable level of
0.5 ppm.
OP25
PRODUCTION FUEL FROM PLASTIC WASTE WITH REACTOR OF 50 KG CAPACITY

AND ITS PERFOMANCE TEST ON MACHINES
Darwanta, Sriyanto
Department of Chemistry, Faculty of MathemaPcs and Natural Science, University
of Cenderawasih
PlasPc waste as a complex problem each country in the world included Indonesia.
Most of development country usually plasPc waste management was not compre-
henship. Many research proved that plasPc waste was potenPal waste converted to
fuel. Although many research only in laboratorium scale that included small weight
sample. Since 2017 , Chemistry Departement in Cenderawasih University had done
producPon of fuel from plasPc waste in pilot plan with reactor of 50 kgs capacity.
Pilot plan was operated in catalityc cracking method with temperature of processes
300-450 oC and powder natural zeolite as a catalyst. This pilot plan have four oulet
product calculated from outlet nearest reactor. This succesfullness program arrived
a new hopeness that prosses developed and implemented in industry and comer-
cially scale. So in the long Pme goals both be2er plasPc waste management and
alternaPve energy source finding.
Research result that 40 kgs of plasPc waste successfully converted to about 34 L of
mix liquid fuel. Mostly of the product was brown-yellowis liquid, easy fluid and easy
burned. The liquid product consisted many fracPon of fuel i.e gasoline, kerosene,
diesel, etc. With fracPonaPon disPllaPon process gasoline fracPon can isolated from
mixture. Gasoline product have characterisPc: very clear, yellowis and very easy
burned. GC-MS of gasoline fracPon showed that more than 90 % as gasoline frac-
Pon like comercial fuel and li2le impuriPes. Octane number parameter was yielded
120 (disPllate product),compared with 88 (premium fuel). ComparaPon of machine
performance test between disPlate product with premium fuel were carried. The
fact showed that respecPvely disPllate product/premium : electricity generator
( 129/128 minutes ), motorcycle ( 44/42 km), minibus car (11/10 km) for every liter.
Based on research result recomanded that plasPc waste prospecPvely and compeP-
Pvely conversed to fuel.
Key words : plas=c waste, alterna=ve fuel, pilot plan
74
OP26
Surface modificaAon and characterizaAon of Fe3O4@SiO2 for recovery of Gold
Roto Roto1 and Vinanda Hayuning Sukma

Dept of Chemistry Universitas Gadjah Mada
Sekip Utara Yogyakarta 55281
1
Corresponding author: roto05@ugm.ac.id
MagnePc nanoparPcles such as magnePte have been studied intensively for their
unique properPes that are suscepPble to a magnePc field, ready to coat with silica
and able to modify with a variety of funcPonal groups. Moreover, the magnePte-
silica core-shell system offers flexibility for extensive modificaPon. In this work, the
magnePc core is coated with tetraethyl orthosilicate (TEOS). Aminopropyl tri-
methoxy silane was used to give an amine funcPonalized surface. Glutaraldehyde
was further used to link the surface with chitosan to give Fe3O4@SiO2 @chitosan.
The produced material has an affinity to absorb Au3+ with a capacity of over 80
mg/g material. This versaPle material is of future absorbents since, a|er adsorp-
Pon, the material together with the ions can be recovered by use of a magnePc
field before further separaPon and purificaPon.
OP27
Study The Influence of DisAllaAonTime on Component Profile of Sweet Fennel
Seeds (Foeniculum vulgare Mill. var. dulce) EssenAal Oils and Its AnAbacterial
AcAvity against Staphylococcus aureus
Rurini RetnowaA*, Suratmo, Risa Maya Romlah
Brawiaya University, and LCAMIA-Research Group, Brawijaya University,
Malang, Indonesia.
Email: rretnowaP@ub.ac.id
Sweet fennel seed (Foeniculum vulgare Mill. var dulce) oils has not become a major
commodity although it has potenPal producPon. IsolaPon of sweet fennel oil can be
done by using steam disPllaPon. One of the factor affecPng disPllaPon process is
Pme disPllaPon. Time disPllaPon influence quality and component profile of
essenPal oils. Components of essenPal oils influence its anPbacterial acPvity. This
study aims to know the Pme disPllaPon influence on yield, physical properPes and
component profile of sweet fennel seeds oils also its anPbacterial acPvity against
Staphylococcus aureus. The isolaPon was done by using steam disPllaPon for 5, 7,
and 9 hours. Physical properPes of sweet fennel seeds oils were determined by its
state and appearance, color, odor, refracPve index and specific gravity. Profile
component was idenPfied using Gas Chromatography-Mass Spectrometer (GC-MS).
AnPbacterial test of sweet fennel seeds oils was done using disk diffusion on S.
aureus. The results showed that yield of sweet fennel seeds oils obtained by steam
disPllaPon respecPvely were 1.1 %, 1.1 % and 1.19 %. The idenPfied components
using GC-MS analysis are 7, 6 and 11 compounds, respecPvely. The five main
components of sweet fennel oil is anethole, fenchone, estragole, limonene and α-
pinene. The highest concentraPon of anethole (77.57 %) was obtained by steam
disPllaPon for 7 hours. Sweet fennel seeds oils obtained in this research is clear
yellow liquid, has disPncPve fennel spicy odor, with mass gravity of 0.967–0.970 g/
mL and refracPve index of 1.53–1.54. The anPbacterial acPvity of sweet fennel seed
oils against S. aureus is classified as resistance category (8-11 mm). Time disPllaPon
influence the yield, component profile and anPbacterial acPvity of sweet fennel
seeds oils against S. aureus, but it does not influence the physical properPes of
sweet fennel seeds oils.
Keywords: sweet fennel oils, steam disPllaPon, Pme disPllaPon, GC-MS,
anPbacterial acPvity test.
76
OP28
The effect of loading zinc oxide to the surface supported

by magnesium fluoride
Diana M. Abulais1, Irmina Kris Murwani1*

1
Department of Chemistry, Mathema=cs and Science Faculty, University of
Cenderawasih
Email: dianabulais@gmail.com
1*
Department of Chemistry, Mathema=cs and Science Faculty, ITS
Email: rmina@chem.its.ac.id
* Corresponding author. Email: irmina@chem.its.ac.id
Synthesis of magnesium fluoride as a catalyst support and zinc oxide sup-

ported on magnesium fluoride was carried out in this study. Magnesium fluoride
support were synthesized by sol gel method, whereas zinc oxide supported on
magnesium fluoride were synthesized by the impregnaPon method. Solid obtained
then measured their surface area by nitrogen adsorpPon-desorpPon method. It
shows that solids have a small surface area value. Based on the observaPon, im-
pregnaPon of zinc oxide on magnesium fluoride with loading variaPon of zinc
oxide 5; 10 and 15% b / b show that the surface area decreases due to zinc oxide
loaded the magnesium fluoride pore.
Key word : magnesium flouride, zinc oxide, impregna=on, surface area

OP29
FTIR and UV-Vis spectrum combined with chemometrics for idenAficaAon and
authenAcaAon method of some medicinal plants
Mohamad Rafi1,2,*, Utami Dyah Syafitri2,3, Irmanida Batubara1,2, Zuhelmi Aziz4

1
Department of Chemistry, Faculty of MathemaPcs and Natural Sciences, Bogor
Agricultural University, Bogor, Indonesia
2
Tropical Biopharmaca Research Center, Bogor Agricultural University, Bogor, Indo-
nesia
3
Department of StaPsPcs, Faculty of MathemaPcs and Natural Sciences, Bogor Ag-
ricultural University, Bogor, Indonesia
4
Faculty of Pharmacy, Pancasila University, Jakarta, Indonesia
*Corresponding author email: mra@apps.ipb.ac.id
IdenPficaPon and authenPcaPon of a medicinal plant before its converted to an

herbal medicinal product is a crucial task to ensure the quality and to prevent adul-
teraPon of a medicinal plant from its related species. An accurate and precise ana-
lyPcal method is necessary to be developed for idenPficaPon and authenPcaPon of
medicinal plant raw material. FingerprinPng approach by using FTIR or UV-Vis spec-
troscopy becomes popular for these purposes. We will have a large amount of data
from FTIR or UV-Vis spectrum, so we need help from chemometrics for data han-
dling and modeling for an idenPficaPon and authenPcaPon methods. In this work,
we described our developed method using FTIR based fingerprinPng for idenPfica-
Pon and authenPcaPon method of Caesalpinia sappan, Curcuma xanthorrhiza, and
Vernonia amygdalina.
Keywords: medicinal plant, idenPficaPon, authenPcaPon, fingerprinPng, FTIR, UV-

Vis, chemometrics.
78
OP30
ADSORPTION OF PHENOL AND 2-CHLOROPHENOL FROM AQUEOUS SOLUTION BY

ACTIVATED CARBON DERIVED FROM BANANA EMPTY FRUIT BUNCH BY HYDRO-
THERMAL-ASSISTED KOH ACTIVATION
Allwar Allwar*, WaAk Mardiah
Department of Chemistry, Faculty MathemaPcs and Natural Sciences, Islamic

University of Indonesia, Yogyakarta, 55584, Indonesia
*Corresponding Author: allwar@uii.ac.id
Telp: +628112551896
Banana empty fruit bunch as a solid waste was successfully converted into acPvated
carbon using KOH acPvaPon under hydrothermal carbonizaPon. AcPvated carbon
was used as adsorbent for the adsorpPon of phenol and 2-chlorophenol from aque-
ous soluPon. Pore structure was intensively studied involving surface area and pore
size distribuPon. BET surface area shows a result of 624 m2/g. BJH method adsorp-
Pon indicates the mesopores with pore radius of 27.2 A. The surface funcPonal
group are O-H, C=O, C-O, C=C analyzed by FTIR. Morphology structure of acPvated
carbon unsmooth surface with varied pore size. AdsorpPon capacity process was
conducted with different pH soluPon, concentraPon, weight of adsorbent and con-
tact Pme. Equilibrium adsorpPon was examined by the Langmuir and Freundlich
models. The results of phenol and 2-chlorophenol adsorpPon is the mostly in the
range of mesopores and macropores relaPng to the Freundlich method with corre-
laPon coefficient (R2) >0.98.
Keywords: Banana empty fruit bunch, Ac=vated carbon, KOH ac=va=on, Hydrother-
mal, Adsorp=on
OP31
An invesAgaAon into the use of sand media planted with Thypa la(folia in
constructed wetland ecotechnology in removing organic maker, suspended solids
and nutrients from domesAc wastewater
P de Rozari and S. M. F Ledoh
Department of Chemistry Faculty of Science and Engineering Nusa Cendana Univer-

sity, Kupang, Indonesia
E-mail: phderozari@yahoo.com or p_derozari@staf.undana.ac.id
DeterioraPon of water quality conPnues to be a major concern in West Timor.

Establishment of wastewater treatment is a crucial for eliminaPng this problem.
Constructed wetland ecotechnologies (CWEs) are an alternaPve low cost
wastewater treatment to solve wastewater problems in West Timor. This research
aims to compare the effecPveness of Thypa la=folia in CWEs for the removal of
BOD, COD, suspended solids, NH4-N, NO3-N and PO4-P. The experimental design
consisted of 6 (20 L) verPcal flow mesocosms; 3 mesocosms planted with Thypa
la=folia and 3 mesocosms as a control. The mesocosms were irrigated with
synthePc wastewater for 6 months. The inflow had a 2-day hydraulic retenPon Pme.
The inflow and oumlow samples were monitored for BOD, COD, suspended solids,
NH4-N, NO3-N and PO4-P. The trend showed that the CWEs planted with Thypa la=-
folia reduced signifcantly the BOD, COD suspended solids, NH4-N, NO3-N and PO4-P.
This indicated that the CWEs planted with Thypa la=folia had a be2er performance in
comparison with the control.
Keywords: Constructed wetlands, Thypa la=folia, nitrogen, phosphorus, mesocosms,

80
OP32
CharacterizaAon of The Dominant Carotenoids in Red Fruit Oil
by Chromatography and Spectroscopy Techniques
Indra Ajie Gunawan1, Heriyanto1,2, Yuzo Shioi2, Leenawaty Limantara2,3, and Tatas H.P.
Brotosudarmo1,2*
1
Department of Chemistry, Faculty of Science and Technology, Universitas Ma Chung, Jl. Villa
Puncak Tidar N-01, Malang 65151, East Java, Indonesia
2
Ma Chung Research Center for Photosynthe=c Pigments (MRCPP), Universitas Ma Chung, Jl.
3
Center for Urban Studies, Universitas Pembangunan Jaya, Jl. Cendrawasih Rata B7/P, South
Tangerang 15413, Banten, Indonesia
*Corresponding author: tatas.brotosudarmo@machung.ac.id
Red fruit (Pandanus conoideus) is an indigenous plant in Papua Island and is well
known to have many funcPons for health, such as lowering blood sugar, prevenPng cancer
[1, 2]. In addiPon, Papua residence uses red fruit as food source, edible oil source, natural
colorant, etc. The red color appearance of red fruit oil is strongly influenced by the presence
of carotenoids. Previously several studies have been idenPfied some minor carotenoids, such
as α- and β-carotenes and α- and β-cryptoxanthins, in the red fruit oil, although the other
dominant carotenoids have not been characterized [3, 4]. The aim of this study is to charac-
terize the dominant carotenoids in red fruit oil by chromatography and spectroscopy tech-
niques. The separaPon and purificaPon of the dominant carotenoids were carried out by
reversed-phase high-performance liquid chromatography (RP-HPLC) using a gradient eluPon
of methanol, methyl ter-buthyl ether and water. The isolated carotenoids were then idenP-
fied based on the spectrophotometric, chromatographic and mass spectrometric properPes
compared to those in the references [5, 6]. Carotenoids from red fruit oil were well separat-
ed within 30 min by HPLC analysis. A trace amount of b-Cryptoxanthin, α- and b-carotenes
were detected, while the dominant carotenoids were eluted in front of those three pro-
vitamin A carotenoids. Five dominant carotenoids had the maximum absorpPon wavelength
(λmax) in the range of 470–480 nm. The mass spectra of the 2nd and 5th dominant carotenoids
showed [M + H]+ at m/z 601.4 and at m/z 569.6, respecPvely. These carotenoids were tenta-
Pvely idenPfied as b-carotenone and semi-b-carotenone from the analysis of molecular ion
and λmax according to Bri2on et al. [6]. Moreover, the absorpPon spectra of these keto-
carotenoids dissolved in several solvents showed different fine structures, indicaPng the
presence of keto group in their molecular structure. The test of funcPonal group and advance
characterizaPon of these carotenoids will be carried out by FT-IR and NMR, respecPvely. b-
Carotenone and semi-b-carotenone were first keto-carotenoids found in red fruit oil and the
other three dominant carotenoids are sPll under the study.
Keywords: carotenoid, characteriza=on, chromatography, red fruit oil, spectroscopy

OP33
Chemical Profiling of Two Medicinal Plants, Kaempferia rotunda and Garcinia cam-
bogia, using UPLC/QTOF-MS
Dyah IswanAni Pradono1,2, Rudi Heryanto1,2, Dewi Anggraini Septaningsih1, Anggia

Murni1
1
Tropical Biopharmaca Research Center, Bogor Agricultural University, Indonesia
2
Department of Chemistry, Faculty of Mathema=cs and Natural Sciences, Bogor Agri-
cultural University, Indonesia
Kaempferia rotunda and Garcinia cambogia is a plant that has been widely
used as a tradiPonal medicine because it has potenPal as an anPcancer, anPbacteri-
al, anP-inflammatory, anPoxidant and anPfungal. This research used ultra-
performance liquid chromatography coupled with quadrupole Pme of flight mass
spectrometry (UPLC/QTOF-MS) to profile the phytochemical of K. rotunda and G.
cambogia. The possible chemical compounds were idenPfied from mass spectra da-
taset using MZmine. The predicPon of the compound is determined by comparing
the m/z with the database of compounds present in the genus kaempferia or
garcinia. EvaluaPon of the MS data showed fourteen compounds were idenPfied on
K. Rotunda. The main consPtuent were had m/z 363. Sesquiterpene dimer, Parviflor-
ene A is contained therein in large quanPPes. Thirty-one compounds were idenPfied
on G. cambogia. Compounds idenPfied belongs to a class of phenolic acids and bifla-
vonoid. Hydrocytric acid (HCA), which is a marker compound of G.cambogia, was
idenPfied at 6.33 min with m/z 209.
Keywords: G. cambogia, K. Rotunda, profiling, UPLC.

82
OP34
Drying Influence of extract on chemical content and xanthine oxidase InhibiAon of

Avicennia marina
Khairul Anam1,2, Rakhman Rosianto1, PurbowaAningrum Ria Sardjono1, Dewi

Kusrini1
1
Department of Chemistry, Faculty of Science and MathemaPcs, Diponegoro Uni-
versity
2
Departement Pharmacy, Faculty of Medicine, Diponegoro University
Corresponding author: k.anam@live.undip.ac.id
Avicennia marina is one of the mangrove species have various properPes in tradi-
Ponal medicine such as for rheumaPsm, skin diseases, inflammatory, contracepPves
and gout medicine. Previous research showed that the aqueous extract of this man-
grove exudate has anPhiperurisemia acPvity. This study was aimed at studying the
drying influence of the extract on the content, chemical composiPon and xanthine
oxidase (XO) inhibiPon of Avicennia marina exudate. Drying the extract is done by
freeze drying and spray dryer. ComposiPon and chemical content were analyzed by
LC-MS. XO inhibitory acPvity performed in vitro. The study results showed that the
method of drying effect on the content and composiPon of the extract. Extracts
were dried by freeze drying method has a be2er XO inhibitory acPvity than spray
drying method
Key Words: xanthine oxidase, Avicennia marina, chemical content, freeze drying,
spray drying
OP35
ExtracAon and characterizaAon of fish oil from various parts of snakehead fish
(Channa striata).
Julius Pontoh
Department of Chemistry
Sam Ratulangi University
Snake head fish (gabus fish) is rich in omega three fa2y acids, therefore it is inter-
sted to study the potenPal for the producPon of omega three suplement. This
study is focused on the extracPon metode for omega three extracPon. Snake head
fish was purchased from lokal fishermen in Lake Tondano, North Sulawesi. The fish
was cuted into three main parts including head, body and viscera. The fish parts
were boiled with water to extract the oil and the fa2y acid composiPon were deter-
mined by gas chromatographic method. The total oil content for whole fresh fish
was 0,41 percent. The highest oil content in the mussles of snakehead fish were in
the head (63.8 %) followed by viscera (19.9 %) and abdomen (16.3 %). The fa2y
acid composiPon of head, viscera and abdomen is consisPng of lauric, palmiPc, pal-
mitoleic, stearic, oleic, linoleic, eicosapentaenoic and docosahexaenoic acids. The
eicosapentaenoic and docosahexaenoic acids are relaPvely lower than those previ-
ously observed.
84
OP36
FabricaAon and Modeling Solar Cell using Gowok Fruit (Syzygium polycephalum)
as SensiAzing and deposiAon TiO2 exert Spin CoaAng Technique
Hubertus Ngaderman1, Ego SrivajawaA2, Sudharmono3
The Focus of this research is DSSC gowok fruit (Syzygium polycephalum), dye has
been comporPng like chlorophyl which absorpPon the light and then producted a
carrier. The purpose of this researches are making DSSC and modeling it’s in order
to finding magnitude of the charge carrier. Modeling with using one of numerical
method i.e least square method for determine several internal parameters
microscopic. The Least Square Method was the method of fiPng curve where the
curve is a funcPon i.e current I as the funcPon of voltage V. DeposiPon TiO2 applying
for technical of Spin CoaPng, characterisPcs of the curent voltage be2er by use of
the method than that of using previously method, automaPcally increasing efficien-
cy. From the analysing of the curve characterisPcs then writer obtain a formulas to
solar cell specifically gowok fruit. The current influenced by the process of harvest
light, electron injecPon, charge collecPon and the maximum voltage under
iluminaPon had been around of difference between quasi Fermi level
semiconductor oxides and redox pairs within electrolyte. The voltage which
retained comes from differences between the level conducPon energy electrode
TiO2 with potenPal of the electrochemical electrolyte of pair redox whereas the
current retained concerned straightly from the number of photon which involved in
the process conversion and dependence at the intensiPes of radiaPon and so the
acPvity of dye which are using. IlluminaPon current IL be equal to ISC that have
value 9,8.10-5 A. A quanPty q related to diffusiPvies and mobiliPes of the carrier.
DiffusiPvies and mobiliPes of the carrier have values that variably while occur
process photocurrent. Since γ of the equaPon solar cell gowok fruit is a funcPon
that change so γ relaPon deeping from voltage (voltage is the variable which can be
changes). It was made too the equaPon of DSSC gowok fruit which presented to the
last equaPon of this research. Writer also finding the charge carrier i.e 0,0044kT.
The LocaPon of the research taken place in the Laboratory of InsPtut Pertanian
Bogor.
Keyword: dye gowok fruit, charge carrier.

OP37
Vapors Induced Phosphorescent Changes in Molecular Self-Assembly of Copper
Pyrazolate Complexes for Chemical Sensors of Methanol to Hexanol
Hendrik O. Lintang1,2,3*, Nur FaPha Ghazalli3, Leny YuliaP1,2,3

1
Ma Chung Research Center for PhotosynthePc Pigments, Universitas Ma Chung, Indonesia
2
Department of Chemistry, Faculty of Science and Technology, Universitas Ma Chung, Indo-
nesia
3
Centre for Sustainable Nanomaterials, UniversiP Teknologi Malaysia, Malaysia
* Email Address: hendrik.lintang@machung.ac.id

Address: Ma Chung Research Center for PhotosynthePc Pigments, Universitas Ma Chung,
Phone Number: +62-341-550171
Azolate complexes with phosphorescent properPes of molecular assemblies via

metal-metal interacPons have received great interest for the chemical sensors of
volaPle organic compounds. However, chemical sensors with high sensing capabil-
ity have not yet been reported using designed complex molecules from various lig-
ands and metal ions. Here, we report molecular self-assembly of copper pyrazolate
complexes, as-synthesized from pyrazole ligands having non-side chain (1A), 3,5-
dimethyl (1B), 3,5-bis(trifluoromethyl) (1C), 3,5-diphenyl) (1D)and 4-(3,5-
dimethoxybenzyl)-3,5-dimethyl (1E) and Group 11 metal ions, for chemical sensors
of alcohol derivaPves such as methanol to hexanol. Among all complexes with phos-
phorescent properPes (emission center at 553-644 nm, large Stoke shi| > 200 nm,
green to red emission and microsecond lifePme), 2E(Cu) showed the best perfor-
mance for sensing through vapor induced phosphorescent changes. Moreover, the
emission and color changes can be recovered without external sPmuli. Such sensing
capability indicates interacPons of the vapors with the molecular assemblies via a
weak intermolecular hydrogen bonding interacPons.
Keywords; Chemical Sensor, Complex, Luminescence, Molecular Assembly, Vapor

86
OP38
Study on the InteracAons between Nitrites, Nitrates,

and Graphene Oxide as a Fluorescence Sensor
Leny YuliaP1-3,*, Tang Ing Hua4, Hasmerya Maarof4, Hendrik O. Lintang1-3

1
Ma Chung Research Center for PhotosynthePc Pigments, Universitas Ma Chung,
2
Department of Chemistry, Faculty of Science and Engineering, Universitas Ma Chung,
3
Centre for Sustainable Nanomaterials, Ibnu Sina InsPtute for ScienPfic and Industrial Re-
search, UniversiP Teknologi Malaysia, 81310 UTM Johor Bahru, Johor, Malaysia
4
Department of Chemistry, Faculty of Science, UniversiP Teknologi Malaysia,
81310 UTM Johor Bahru, Johor, Malaysia
*Corresponding Author. Email address: leny.yuliaP@machung.ac.id
The existence of nitrite and nitrate ions in water could lead to negaPve effects to
both human and environments. Graphene oxide has been reported as a potenPal
fluorescence sensor for detecPon of these ions. In this study, we further revealed
the use of the graphene oxide for detecPon of nitrate and nitrite ions up to 100
mM. The reproducibility and the sensiPvity in the presence of other interference
ions were also evaluated. The computaPonal study showed that among the possible
sensing sites in graphene oxide, the hydroxyl and carboxyl sites were confirmed to
show superior binding energy for nitrites and nitrates. The interatomic distances
between these sensing sites and nitrites were closer than those between the sens-
ing sites and nitrates. It was suggested that the interacPons came from the hydro-
gen bonding. The stronger interacPons between the graphene oxide and nitrites led
to be2er detecPon towards the nitrites than the nitrates.
OP39
STANDARDIZATION OF EXTRACTION METHODS OF GELATIN FROM Lutjanus sp.

SCALES
Meliana Wahyuningtyas1, Nurul Jadid1, Perry Burhan1, Lukman Atmaja1,*

1
Departemen Kimia, Fakultas Ilmu Alam, Ins=tut Teknologi Sepuluh Nopember,
Sukolilo, Surabaya 60111, Indonesia
*Corresponding author : lukman_at@chem.its.ac.id, phone : 00-62-31-5943353
The extent of applicaPons in various fields makes the need for gelaPn conPnue to
increase in the global market. Fish gelaPn is an alternaPve to mammalian gelaPn
and its use is more universal because it can be consumed by all religious followers.
Fish gelaPn has never been mass produced in Indonesia. Although the laboratory
scale of fish gelaPn has been successfully carried out, the standardizaPon process to
achieve commercial standards has also never reported. In this study, gelaPn
extracPon from Red Snapper scales was conducted chemically using acid as a curing
soluPon, i.e., HCl, H3PO4 and CH3COOH. The opPmum condiPons in the extracPon
standardizaPon obtained were using 1% curing H3PO4 soluPon for 24 hours with an
extracPon temperature of 80 °C for 4 hours, i.e., using parameters of swelling
degree of 95.96 ± 0.54%, yield of 20.37 ± 0.23%, melPng point of 60 °C and water
content of 4,395 ± 0.025%. The existance of gelaPn was confirmed by FT-IR spectra.
Key words : GelaPn, Red Snapper scales, StandardizaPon

88
OP40
The Influence of CalcinaAon Temperature to Mineral ComposiAon in the Man-

grove Crab Shells (Scylla serrata) from Merauke
E HaryaP*1), K Dahlan1), O Togibasa1), K Dahlan2)

1)
Department of Physics - Cenderawasih University, Indonesia
2)
Department of Physics - Bogor Agricultural InsPtute, Indonesia
*) corresponding author: endanghfis@gmail.com
The analyses over mineral content of mangrove crab shells from Merauke have
been studied. The shells of the mangrove crab that have been cleansed and dried
under the sun for 24 hours, were mashed and then divide into two parts. The first
secPon was used for the analyses of mineral composiPon, while the second part
was previously calcined at three different temperature, 1173 K, 1273 K and 1373 K
for 5 hours before analysed. The results showed that the raw powder of mangrove
crab shell was contained 90,46% of calcium and 9,64% of other mineral content.
The calcined process has succeeded to decrease the carbon content. It can be con-
cluded that the mangrove crab shells from Merauke possess basic materials as bioc-
eramic.
OP41
FISH DIVERSITY OF MANGROVE ECOSYSTEM

IN DEMTA GULF JAYAPURA PAPUA
John D. Kalor1, Ervina Indrayani2, Baigo Hamuna3, Alfred Matekohi

1
Program Marine Sciences, 2Program Fisheries Sciences, and 3Program EducaPon of
Biology. Faculty MathemaPcs and Sciences Universitas Cenderawasih, Jayapura,
Papua, Indonesia. Corresponding author: John Dominggus Kalor,
john_pela@yahoo.com
Abstract
The Morphology, ecologycal, and biological condiPon on Demta Gulf is forming an
ecosystem zone consisPng of coral reefs ecosystem, seagrass, and mangrove.
Mangrove ecosystem is very usefull as habitat, nursery ground, feeding ground, and
spawning ground for various species of fish. This study was conducted from April to
June 2018 in the mangrove ecosystem of Demta Gulf, Demta District, Jayapura
regency, Papua. There were 3 research staPons with 3 transects per staPon so that
9 transects and 28 fish capture effords. Data analysis were provided by Shannon-
Wiener Diversity Index (H), Equivalence Analysis (E), Abundance Analysis. The result
showed that Mangrove ecosystem of Demta Gulf had high fisheries resources was
consisted of 21 families and 30 species. The level of diversity in St. Ambora is high
2.4 and abundance was 2241 individual/ ha, St. Yougapsa is high 2.8 and abundance
was 1808 individual/ ha, Ambora-Tarfia is high 2.8 and abundance was 2550
individual/ ha. Fish resources and producPvity will be highest and increase where
mangrove producPvity is hight, the total area of mangrove is an increase, and
mangroves have greater physical complexity.
Key words: Fish, Mangrove, Demta, Jayapura, Papua

90
OP42
PreparaAon and Physico-Chemical ProperAes of Gracilaria/PVA/GA/CNT-Based

Hydrogel for Slow/Controlled Release Material
Hendrawan Hendrawan1), Fitri Khoerunnisa2) , Ferina Ihsani EkawaP3) , Yaya

Sonjaya4)
1,2,3,4)
Department of Chemistry, Universitas Pendidikan Indonesia
E-mail: hendrawan@upi.edu, phone: +62-8122487570
Abstract
Due to its applicaPon prospect, especially for slow/controlled release ferPlizer, drug
delivery, ion exchanger, and absorbent materials, hydrogel has been becoming an
a2racPve material and being great interest of many scienPsts. However, the use of
biodiversity-based hydrogels is sPll limited. In this study, we have synthesized a hy-
drogel from composites of gracillaria (GR), poly-vinyl alcohol (PVA), glutaraldehyde
(GA), and carbon nanotube (CNT) later then denoted as GR/PVA/GA and GR/PVA/
GA/CNT for sample without and with CNT addiPon, respecPvely. In parPcular, two
kinds of PVA (technical and pro analysis grades) were used in this study. The charac-
terizaPon of hydrogels was conducted by means of FTIR and SEM. Meanwhile, the
performance parameters of hydrogels i.e. swelling raPo, water retenPon, and re-
lease behavior of potassium from hydrogel into aqueous media were evaluated.
FTIR spectra showed that the interacPon of hydrogel components involved some
funcPonal groups. Meanwhile, the SEM images confirmed that the hydrogels were
porous like material. The swelling raPo of technical PVA-based hydrogel was higher
than that of pro-analysis one. Similarly, the hydrogel dried in incubator exhibited
higher swelling raPo than that of dried without incubator. AddiPonally, the hydro-
gel demonstrated larger water retenPon. InserPon of CNT and K ions into hydrogel
remarkably increased water retenPon. The hydrogel showed a typical slow release
behavior for potassium ion. It can be inferred that the synthesized hydrogel is
promising to be applied as slow-controlled release material (S-CRM).
Keywords: hydrogel, gracilaria, poly-vynil alcohol, CNT, S-CRM.

OP43
AnAbacterial AcAvity of Three Dendrobium species from Papua Against Eschericia

coli and Staphylococcus aureus
VERENA AGUSTINI*1, SUPENI SUFAATI*1, AGNES ERI MARYUNI*2, EVA SUSANTI

SIMAREMARE*3
1
Department of Biology, MathemaPc and Science Faculty, University of
Cenderawasih
2
Department of Chemistry, MathemaPc and Science Faculty, University of
Cenderawasih
3
Department of Pharmacy, MathemaPc and Science Faculty of Cenderawasih
University
Email: verena.agusPni@gmail.com
Orchid found as one of medicinal plant in some areas, especially Dendrobium. Some
species were invesPgated its anPbacterial acPvity, but the informaPon about
anPbacterial acPvity of Papuan Dendrobium species is sPll limited. The aim of this
research was to determine the anPbacterial acPvity of Dendrobium species from
Papua against Escherichia coli and Staphylococcus aureus. There are three species
of Dendrobium; Dendrobium spectabile (leaves and stem), Dendrobium
violaceoflaveus (leaves and stem), and Dendrobium antenatum (stem). Dried
simplisia was maserated using ethanol, then tested for the phytochemical content.
Total ethanolic extract was fracPonated into three fracPons (ethanol, ethyl acetate
and hexane fracPons). Disc diffusion assay was used to examine the anPbacterial
acPvity of the total extract and the fracPons.Total extract are posiPve for flavonoid,
alkaloid and tanin, except Dendrobium spectabile stem extract. Saponin was not
found in all of the total extract. The highest acPvity resulted from ethyl acetat
extract of Dendrobium spectabile leaves in inhibiPng S. aureus with diameter zone
20,5443 ± 1,4741 mm. It is indicated that the ethyl acetat of Dendrobium spectabile
leaves is potenPal to be developed in anPbacterial drug design research.
Keywords: an=bacterial ac=vity, Papua, Dendrobium, Escherichia coli,

Staphylococcus aureus
92
OP44
PRECLINICAL TRIALS OF ANTI-ATHEROSCLEROTIC EXTRACT OF INOCARPUS

FAGIFERUS FOSB SEEDS IN BALI
I Made Sukadana1* and Sri Rahayu SanP2

1,2
Departement of Chemistry-Faculty of Science and Maths Udayana University
*Corresponding author: im_sukadana@unud.ac.id
Seed of Inocarpus fagiferus Fosb is empirically having an ability to reduce

oxidaPve stress diseases. In this paper to describing the result of preclinical trials of
ethanol extract from Inocarpus fagiferus Fosb seed in Bali to reduce oxidaPve stress
especially to prevent atherosclerosis through some variables such as SOD acPvity,
lipid profile, MDA, SOD-3, SOD-2, and ICAM-1 expression. The anP-atheroscleroPc
of ethanol extracts from Inocarpus fagiferus Fosb seed was proved on wistar rat
with high cholesterol diet for 16 weeks with randomized pos2est only control group
design. The samples were 25 wistar rat, randomized into 2 control and 3 treatment
groups, i.e. P0 (negaPve control), P1 (posiPve control, feed high cholesterol diet), P2
(high cholesterol diet and ethanol extract in dose of 50 mg/kg bw), P3 (high
cholesterol diet and ethanol extract in dose of 100 mg/kg bw), and P4 (high
cholesterol diet and ethanol extract in dose of 150 mg/kg bw). A|er 16 weeks
treatment, blood of the rats were driven for SOD acPvity, lipid profile, MDA and
aorta for immunohistochemistry analyzed to give expression of SOD-3, SOD-2 and
ICAM-1 datas. The results showed that doses of 50 mg/kg bw increases in
percentage of rate inhibiPon (SOD acPvity) (p<0.05), decrease to total cholesterol
and triglyceride level (p<0.05) but tends to uncahanged of HDL and LDL cholesterol
levels (p>0.05), increase the expression of posiPve SOD-3 and SOD-2 aorta
endhotel cell but decrease of posiPve ICAM-1 and decrease the concentraPon of
MDA significantly (p <0.05) compared to P1.
Keywords: Inocarpus fagiferus Fosb, an=-atherosclerosis, oxida=ve stress and

preclinical trial
OP45
AnAoxidant AcAvity Test of Extract Infusion from Stem of Yellow Rope

(Archangelsia.Flava.(L)Merr)
Alowisya.Futwembun (1).Elizabeth.Holle,(1) Yuliana.R.Yabansabra

(1)
.Eva.S.Simaremare (2), Fransisika..Toteng(2)
Chemistry Department of Math And Science Faculty Cenderawasih University
Pharmacy Department of Math And Science Faculty Cenderawasih University
Email : yyabansabra@yahoo.com
Yellow rope (Archangelisia flava) is known as a vine plant mostly found in the
forests of Papua, West Papua and Kalimantan. TradiPonally, this plant used by the
indigenous people of Papua for health recovery, cleaning postpartum (puerperal
women), and fever (caused by malaria). This study was aimed to determine the
content of secondary metabolites and to test the anPoxidant acPvity of bark extract
infusion from yellow rope. ExtracPon method was applied in this research followed
by evaporaPon to produce condensed extract product/dry product which further
used for phytochemicals and anPoxidant tests. Screening of phytochemical test was
done using chemical reagents while the anPoxidant test applied free radical meth-
od DPPH. The results showed that the water extract of the bark of yellow string
contains as much as 8.36% of a group of secondary metabolites called terpenoids,
alkaloids and flavonoids. Furthermore, anPoxidant test obtained IC50 correspond-
ing to a value of 49.04 mg / mL in which categorized as very strong.
Keywords : Yellow rope, infusion, anPoxidant
94
OP46
An(coagulan Ac(vity of Ethanolic Extract S(ngging NeUle (Laportea aestuans (L)

Chew) from Biak Numfor
Eva Susanty Simaremare1, Elizabeth Holle2, Yuliana Yabansabra2, Elsye Gunawan1,

Rizqa Fauziyah Fadhilah1
1
Program Studi Farmasi Jurusan Farmasi Fakultas MIPA Universitas Cenderawasih,
Jayapura
2
Program Studi Kimia Jurusan Kimia Fakultas MIPA Universitas Cenderawasih,
Jayapura
(email: eva_smare@yahoo.com)
SPnging ne2le (Laportea aestuans (Linn) Chew) have been used empirically as re-
lieving pain such as sPffness, headache, abdominal pain, muscle aches, joints and
bruises. The aims of this study was to determine the effect of ethanol extract of
sPnging ne2le leaf as an anPcoagulant that used human blood (A, B, O and AB)
using Lee-white method and blood smear. The sPnging ne2le leaf samples were
taken from Biak Numfor, made simplicia, and macerated by 96% ethanol. The anP-
coagulant acPvity of ethanol extract was tested with preliminary of 50, 100, 150,
200, and 250 ppm. Then test was followed by anPcoagulant acPvity by Lee White
method and eustek method (blood smear). The results showed that in the prelimi-
nary test the minimum concentraPon of extracts of 45 ppm was observed for 120
minutes. Extracts Laportea aestuans have anPcoagulant acPvity against various
human blood groups as well as posiPve controls of EDTA. Both of them can binding
calcium that the blood clojng factors so blood did not freeze. Blood clojng acPvi-
ty by eustek method showed that the extract of Laportea aestuans seen in the mi-
croscopic blood cells did not freeze because the unrelated blood cells were intact
and separated from each other.
OP47
VICTORIA GROUND PIGEON (Goura victoria) and THEIR FOOD PLANTS

IN THE NIMBOKRANG FOREST AREA of JAYAPURA- PAPUA
Henderina J. Keiluhu1*, Margaretha Z. Pangau1), Hendra K. Maury1)
.
1. Biology Department of FMIPA Cenderawasih University, Jayapura Papua
Indonesia
*Corresponding author: henderinaj.keiluhu@gmail.com
An ecological study to find out the species of food plants of Victoria ground pigeon
(Goura vicoria) was taken in the Yenggu Village in the Nimbokrang forest area of
District Jayapura, Papua. Specific purposes of the research was to obtain the
informaPon about plants species including fruits and other parts which were used
as natural food of Goura victoria as their natural feed. Data collecPon was carried
out during June-July 2018, used survey method with interview technique. The
research showed that only 16 species of plants from 12 families were naturally
documented as Goura victoria food. Goura victoria preferred mostly fruits and
usually le| other plant’s part such as shoot, leaves and twigs. The size of edible
fruits ranged from 2.10 mm to 55.40 mm on diameter while fruit colors recorded as
red, orange, green and red-purple black.
Key word: Victoria ground pigeon, food plants, Yenggu Village, Papua
96
OP48
POPULATION ANALYSIS OF D-loop mtDNA BUFFALO (Bubalus bubalis &

Syncerus caffer) SEQUENCES FROM GENBANK DDBJ
Susilo, T. B. *#, Masturini, Y.,*.and Soesanto **

*#Program Study of Chemistry, Faculty of MathemaPcs and Natural Sciences,
Lambung Mangkurat University, Jl. A. Yani Km 35,5 Banjarbaru, Kal Sel; **Program
Study of MathemaPcs, Faculty of MathemaPcs and Natural Sciences, Lambung
Mangkurat University, Jl. A. Yani Km 35,5 Banjarbaru, Kal Sel *#Corresponding au-
thor: tbi.susilo@yahoo.co.id
D-loop Mitochondrial DNA (mtDNA) of buffalo’s sequences had been used as a de-
terminant of genePc distance and spread of migraPon that useful for study of hu-
man prehistory migraPon. The study of Bubalus bubalis had been conducted in
Egypt, China, India, Indonesia, Ireland, Pakistan, Philippines, and Thailand; for Buba-
lus bubalis carabanensis in India; and for Syncerus caffer in South Africa, Belgium,
Netherland, Denmark, and Norway, however overall it had not been summarized.
This is study by collecPng 400 D-loop Mitochondrial DNA (mtDNA) of buffalo’s se-
quences from GenBank DDBJ. Furthermore, it was analyzed by Spreadsheet, PHYLIP,
ANN methods and visualizaPon by using TreeView and MatLab. The result is showed
that genePc distance was 0 between DQ364163 (China), KR872756 (Indonesia), and
KR872764 (Indonesia) by Spreadsheet method and the spread centered was India
by ANN (MatLab) method. GenePc distance was 100% between DQ364163 (China),
KR872756 (Indonesia), and KR872764 (Indonesia) by PHYLIP method and the spread
centered was China by TreeView. GenePc distance was 0,2040 between the China
and Indonesia populaPons and spread centered was Norway by Spreadsheet meth-
od. GenePc distance was 0,1460 between the China and Indonesia populaPons and
the spread centered was Norway by ANN (MatLab) method.
Keywords: D-loop mtDNA of Buffalo, DDBJ, ANN

OP49
AnAbacterial AcAvity of Daun Afrika Extract (Vernonia amygdalina) Papua to
Staphylococcus aureus and Escherichia coli Bacterial
Rani Dewi PraPwi, Elsye Gunawan

Departement of Pharmacy, Cenderawasih University Papua 99351 Indonesia
ranidp2987@gmail.com
Daun Afrika from Papua widely uPlized by local people, one of them to treat acne.
Some research of Vernonia amygdalina contained flavonoids, tannins, saponins
andterpenoids. The aim of this study was to invesPgate the AnPbacterial AcPvity of
Vernonia amygdalina Extract from Papua to Staphylococcus aureus and Escherichia
coli bacterial byusing Diffusion Assay. Research result show that the extract inhibit-
ed the growth of Staphylococcus aureus and Escherichia coli. InhibiPon zone was
observed in leaf ofVernonia amygdalina agains Staphylococcus aureus 100 µg/ml
(6,69 mm) and Escherichiacoli 100 µg/ml (6,52 mm) respecPvely. The extract of
Vernonia amygdalina leaves fromPapua has a anPbacterial acPvity at minimum
concentraPon extract, can be taken as good evidence for a possible aplicaPon of
those compounds as anPbagterial agents.
Keywords : An=bacterial, Vernonia amygdalina, Staphylococcus aureus, Escherichia

coli
98
OP50
Test AcAvity AnAcoagulant Ethanol extract daun jilat (Villebrunea rubescens)

Against Human Blood.
Elsye Gunawan1, Rovildo V. Labery1, Septriyanto Dirgantara1

1
Pharmacy Study Program, Department of Pharmacy, Faculty of Mathema=cs and
Natural Sciences, Cenderawasih University
Daun jilat (Villebrunea rubescens) is one of the tradiPonal remedies in the Yapen
Islands District that is empirically used to treat bruises or bruises. The samples of
daun jilat used were taken from the Yapen Islands Regency and macerated with
96% ethanol. This study aims to determine the acPvity of anPcoagulant extract eta-
nol daun jilat (Villebrunea rubescens) against various types of human blood group.
The method used is Lee-white and Eustek (blood smear) with a concentraPon of 250
ppm. The results obtained from ethanol extract of daun jilat on Lee-white and
Eustek methods indicate the existence of anPcoagulant acPvity against various
types of human blood group.
OP51
Mitochondrial genome mutaAon analysis: Papuan mtG comparaAon with several
GenBank sequence data on gene control and encoding regions
Yohanis Ngili,1 Johnson Siallagan, 1 Rosye H. R. Tanjung,2

and Epiphani I. Y. Palit, 3
1
University of Cenderawasih, Jayapura, Indonesia
2
Department of Biology, Faculty of MathemaPcs and Natural Sciences,
University of Cenderawasih, Jayapura, Indonesia
3
BiostaPsPcs Division, Department of MathemaPcs and Natural Sciences, Universi-
ty of Cenderawasih, Jayapura, Indonesia
ComparaPve study of DNA mutaPons occurring in human mitochondrial genomes

in Papuan humans and its comparison with some ethnic worlds has been studied.
The aims of this study was to analyze mutant variants in all the complete human
genome mitochondrial areas by using repli-G techniques for mitochondrial
genomic amplificaPon, the result of Papuan human nucleoPde sequencing was
then compared against some individuals represenPng some ethniciPes in the
world. DNA samples were isolated from human Pssue and then sequenced using
10 pairs of primers to amplify human mtG. The mtG sequence is aligned and
compared with rCRS using the DNAstar program. The result of mutaPon analysis
shows the presence of point mutaPon in some mtG region fragments with
different mutaPon proporPons. Most mutaPons outside the HVS1 and HVS2 D-
loops are in the ATP6 region. The encoding region of ATP6 is the gene coding
region of human mtG and shows a high mutaPon rate of CRS. This opens a new
paradigm for mutaPon analysis on ATP6 areas other than the mtG D-loop. The
ATP6 gene segment located at 8553-8902 can be selected for studies in populaPon
genePcs, forensic medicine and bioethnoanthropology studies, in addiPon to the
HVS1/HVS2 D-loop areas that have been used.
Keywords: mtG genome, variant, mtDNA, muta=on, Indonesian, ethnic groups

100
OP52
NutriAon and anAoxidant properAes of Pleurotus sajor-caju
from Jayapura, Papua
Supeni SufaaA*1), Rosye H.R.Tanjung1), Septriyanto Dirgantara2), Verena AgusAni1),

SepAani Mangiwa3) and Suharno1)
1)
Department of Biology, Faculty of MathemaPcs and Natural Science,
Cenderawasih University, Jayapura, Papua
2)
Department of Pharmacy, Faculty of MathemaPcs and Natural Science,
3)
Department of Chemistry, Faculty of MathemaPcs and Natural Science,
*) penisufaaP@gmail.com
Pleurotus sajor-caju is one of the wild edible mushrooms consumed by people in

Jayapura, Papua and is known by the local name as Tambir. Tambir consumed as a
vegetable because it is believed to contain nutrients. This study aims to determine
the composiPon of nutrient content and anPoxidant properPes of Tambir. Samples
were collected from tradiPonal market in Perumnas 3 Waena, Jayapura. The com-
posiPon of nutrient content was performed by proximate analysis (water, ash, fat,
crude protein and carbohydrate content). The Gravimetric method was used to
analysis the water and ash content, Soxhlet for fat content, Kjeldahl for crude pro-
tein content and Luff Schoorl for carbohydrate. Phytochemical screening of alka-
loids, flavonoids, terpenoids, steroids, tannins and saponins was carried out using
standard methods. The anPoxidant properPes was determined by scavenging acPvi-
ty on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals against the methanolic extracts
of Tambir and measured by spectrophotometry Uv-Vis at 517 nm wavelength. The
results showed that Tambir has 12. 1 % water content, 5.53 % ash content, 1.16 %
fat content, 28.5 % crude protein and 23.5 % carbohydrate. The methanolic extracts
of wet and dried mushroom showed that both extract contained alkaloids and sap-
onins. While, the radical scavenging acPvity was 68.20 % and 39.40 %, respecPvely
at 25 mg/ml concentraPon. Therefore Tambir can be used as a source of nutriPon,
especially protein but has no potenPal as an anPoxidant.
Keywords : Pleurotus sajor-caju, Tambir, wild edible mushroom, nutri=on, an=oxi-

dant proper=es.
OP53
CharaterizaAon of Microalgae from Freshwater Pond of Buper Jayapura and from
Seawater of Harlen Beach Jayapura Based on Their Lipids, Chlorophylls, Protein,
and Carbohydrate Contents
Yohanis Ngili, Frans Agus=nus Asmuruf, Budi P. Waromi, Yohanis Irenius Mandik*
Department of Chemistry, Faculty of MathemaPcs and Natural Sciences, University

of Cenderawasih, Jalan Kamp Walker, Jayapura 99358, Indonesia.
Email address: yimandik@gmail.com
Microalgae were known as photosynthePc microorganism which has great potenPal

to be developed as biodiesel feedstock. This research was conducted to isolate, to
culPvate and to characterize potenPal species of marine and freshwater microalgae
from Jayapura, as Jayapura located close to equator therefore mostly exposes to
sun light along year. The chlorophylls content, lipid content, protein content, and
carbohydrate content of selected microalgae were characterized a|er culPvaPng in
urea and NPK ferPlizer liquid growth medium which is a low cost medium. Several
species of microalgae were isolated and idenPfied as marine Chlorella sp. and ma-
rine Zoochlorella sp. from Harlen beach area of Jayapura while Freshwater Chlorella
sp. were from Buper Freshwater pond of Jayapura. Furthermore, both marine Chlo-
rella sp. and freshwater Chlorella sp. which grew well were subsequently selected to
culPvate for larger scale. Chlorophylls content of freshwater Chlorella sp., harvest-
ed at the peak of growth rate were 2.837 0.149 mg/L while the lipids content
was 13-37%, Protein content was 48.22%, and Carbohydrate content was 12.29%.
Meanwhile, Chlorophylls content of marine Chlorella sp., harvested at the peak of
growth rate were 2.046 0.343 mg/L while the lipids content was 6-28%, Protein
content was 36.48%, and Carbohydrate content was 16.50%. Both of Jayapura iso-
lates of freshwater Chlorella sp. and marine Chlorella sp., exhibit great ability to
grow in a cheap ferPlizer containing medium. The lipids could be uPlized as bio-
diesel feedstock, the chlorophylls are applicable as healthy food supplement and
anPoxidant products, the carbohydrate could be uPlized for fermentable sugar pro-
ducPon, while protein could be applied in animal feed producPon.
Keywords: biodiesel, chlorophylls, freshwater Chlorella sp., marine Chlorella sp.,

Jayapura Isolate Microalgae
102
OP 54
Coconut Oil ProducAon via Coconut Cream FermentaAon by
Lactobacillus bulgaricus
Pandu SiagawaAningtyas1, Agnes Eri Maryuni1, Yohanis Irenius Mandik1, Maria

Bintang2
1
Department of Chemistry, Faculty of Mathema=cs and Natural Sciences, University
of Cenderawasih, Jalan Kamp Walker, Jayapura 99358, Indonesia
2
Department of Biochemistry, Faculty of Mathema=cs and Natural Sciences,Bogor
Agricultural University
Corresponding author: Yohanis Irenius Mandik; s202aniz@yahoo.com; Department

of Chemistry, Faculty of MathemaPcs and Natural Sciences, University of
Cenderawasih, Jalan Kamp Walker, Jayapura 99358, Indonesia
Coconut cream fermentaPon was performed by Lactobacillus bulgaricus

to produce coconut oil. This research aimed to find a low temperature process of
coconut oil producPon as well as to improve the quality of the oil. The emulsion
equilibrium of the protein, oil and water in coconut cream was broken down by the
bacterial proteolyPc acPvity. Then the coconut oil was released from the emulsion
to the fermentaPon mixtures. The highest volume of oil produced was 28.15 mL
which was obtained from the inoculum concentraPon of 7% (v/v) in 100 mL of sub-
strate (coconut cream) and fermentaPon Pme of 36 hour, at incubaPon tempera-
ture of 30 oC. Furthermore, the product exhibited great characterisPcs as follow-
ing, water content was 0.14%, iodine number was 8.819, saponificaPon number
was 238.819, peroxide number was 2.811 and the free fa2y acid was 0.106%. This
method shows promising potenPals in the field of coconut oil producPon, consid-
ering its high quality product, low energy consumpPon, and low environmental
cost.
Keywords: coconut cream, coconut oil, emulsion, fermenta=on, Lactobacillus bul-

garicus
ABSTRACTS OF POSTER PRESENTATIONS

104
PP01
PreparaAon of chitosan with variaAons of molecular weight and its effect on de-
polymerizaAon of chitosan with hydrogen peroxide using microwave technique
Matheis F.J.D.P. Tanasale*, Catherina M. Bijang, AfriyanP Ohorella

Department of Chemistry, Faculty of MathemaPcs and Natural Sciences, Pajmura
University
*
email: mtanasale@fmipa.unpaj.ac.id, taste724@yahoo.com
Abstract
Chitosan depolymerized with hydrogen peroxide (H2O2) using microwave technique
has been done by varying molecular weight of chitosan. This study aims to deter-
mine opPmum condiPons of chitosan depolymerizaPon and influence of molecular
weight for preparaPon of chitosan depolymerized. Chitosan was produced with
different molecular weight by variaPon of chitosan heaPng Pme in 5% acePc acid
for 2, 12, 24, and 24 hours and molecular weight of chitosan was determined by the
viscometric method. Chitosan produced from technical chiPn has molecular weight
7.90 x 103 (TC-2), 6.70 x 103 (TC-12), 6.50 x 103 (TC-24) and 5.60 x 103 g/mol (TC-
120) for 2, 12, 24, and 120 hours of heaPng Pme, respecPvely. These results sug-
gest that the resulPng chitosan was affected by the heaPng Pme. The longer heaPng
Pme, the lower molecular weight of chitosan are produced. Next, the chitosan has
depolymerized by varying concentraPon of H2O2 and depolymerizaPon irradiaPon
Pme using microwave technique. The process of depolymerizing chitosan with H2O2
was influenced by H2O2 concentraPon and irradiaPon Pme which the opPmum con-
diPons were 6% H2O2 and irradiaPon Pme for 75 seconds for TC-2 which produced
oligochitosan with molecular weight of 3.5 x 103 g/mol and rendemen 25.65%.
Keywords: chitosan, depolymeriza=on, hidrogen peroxide, oligochitosan, , micro-

wave technique
PP02
Synthesis of magneAte/TiO2-Cu as recoverable and sensiAve photocatalyst under
visible light radiaAon
M. Miqdam Musawwa1), Eko Sri KunarP2), Sutarno2)
1)
Department of Chemistry, Faculty of Mathema=c and Natural Sciences,
Universitas Islam Indonesia
2)
Department of Chemistry, Faculty of Mathema=c and Natural Sciences, Gadjah
Mada University
Corresponding author: muhmiqdam@gmail.com (085641761731)
Synthesis of magnePte/TiO2-Cu as alternaPve photocatalyst to overcome the pure

Ptania deficiencies has been done in this study. The aim of magnePzaPon was to
give magnePc properPes so that the photocatalyst being recoverable a|er its
using. Cu doping aims to make photocatalysts sensiPve to visible light radiaPon.
MagnePte (Fe3O4) was synthesized through precipitaPon process. The doping
process was carried out by sol gel method. The results of X-Ray DiffracPon (XRD)
showed characterisPc peaks of magnePte were at 2θ (o) 30; 35; 43; 53.9; 57; 62,
73.9 and Ptania peaks were at 25.38; 38.7; 48.54, 54.06; 55.2, 62.88. Transmission
Electron Microscopy (TEM) has confirmed the spherical form of material
synthesized with the size around were 25 nm. MagnePc ability was confirmed
quanPtaPvely by VibraPng-sample magnetometer (VSM) as 6.98 emu g-1 and
qualitaPvely was confirmed by its interacPon with external magnets. Based on the
characterizaPon datas, the magnePte /TiO2-Cu confirmed to be successfully
synthesized.
Key words: photocatalyst, magnePte, TiO2-Cu
106
PP03
Study and FormulaAon of Anionic Surfactang For Enhanced Oil Recovery
Nurcahyo Iman Prakoso1,a), Agung Prayudia Maulana1,b), YulianA1,c), Harianto1,d),
Tufia Nurfitriani Febri1,e), Hafidha Tri KurniaA1,f)
1
Chemistry Department, Universitas Islam Indonesia.
a)Corresponding author: nurcahyo.ip@uii.ac.id
Sodium Ligno Sulphonate (SLS) is one of the types of anionic surfactants that can be
made from oil palm empty fruit bunches’s lignin. Therefore, these surfactants have
the opportunity to applied as cheap EOR agent because of the presence of highly
abundant raw materials. In this study, we invesPgated the ability of lone SLS and
mixed SLS with some support materials as EOR agent. In the iniPal screening, we
conducted IFT test for selecPng viable EOR agent where surfactant's IFT value must
be in range 10-3 mN/M. This test was very important for a preliminary test like core
flooding and another advanced test. The results demonstrated that SLS can’t stand
alone as EOR agent and must be blended with another supporPng materials like Na-
fa2y acid and cosolvent. There are 4 surfactant formulas that potenPally as EOR
agent, BRP14, CRP14, B3RP14, F1RP14 and HRP14.
Keywords : SLS, EOR, Surfactant

PP04
THE INFLUENCE OF FERMENTATION TIME AND CELLULASE ENZYME VOLUME OF

OYSTER MUSHROOM STEM AT BIOETHANOL PRODUCTION FROM RICE STRAW
USING SIMULTANEOUS SACCHARIFICATION AND FERMENTATION (SSF) METHOD
Tatang Shabur Julianto, Arsyik Kurniawan, dan Ikhwan Arifin

Department of Chemistry, Faculty of Mathema=cs and Natural Sciences
Universitas Islam Indonesia, Yogyakarta
Email: tatang_shabur@uii.ac.id
A study in producPon of bioethanol from rice straw using SSF method has
been done. Rice straw is an agricultular waste containing lignocellulose that can be
uPlized for manufacturing alternaPve energy such as bioethanol. This study aimed
to determine the opPmum both fermentaPon Pme and volume of cellulose enzyme
on the concentraPon of ethanol produced, also to know the effect of base
pretreatment on straw sample on the concentraPon of ethanol produced. The
method used is SSF (Simultaneous Saccharifica=on and Fermenta=on) where the
process of hydrolysis and fermentaPon was done simultaneusly. The advantages of
this process are the short period of SaccharificaPon and FermentaPon, occuring in
one reactor and saving the producPon cost. The hydrolysis process was carried out
by cellulase enzyme extracted from oyster mushroom stem, while the fermentaPon
process was done by yeast S. cerevisiae. The rice straw samples were smoothed and
dried to remove the moisture content. The samples were mixed into an SSF
medium containing aquadest, cellulase enzymes and yeast S. Cerevisiae and then
fermented for several days. Cellulose content in straw would be hydrolyzed into
glucose by cellulase enzymes, and then would be directly converted to ethanol by
yeast S. Cerevisiae. PurificaPon of ethanol was done by simple disPllaPon. Variables
used were cellulase enzyme volume and fermentaPon Pme. VariaPons in cellulase
enzyme volume ranged from 0, 10, 15, 20 and 25 mL. While the fermentaPon Pme
starts from 2, 4, 6, 8 and 10 days. Based on the results of the research, it was found
that the highest bioethanol concentraPon was 14.52% with the variaPon of 10 days
fermentaPon Pme and 25 mL enzyme volume, while the bioethanol concentraPon
in the control sample (base pretreatment) was 9.75%.
Keywords : Bioethanol, Oyster Mushroom, Rice Straw, Simultaneous

Saccharifica=on and Fermenta=on (SSF).
108
PP05
Green Synthesis of Gold-Palladium Core-Shell NanoparAcles (Au@Pd CSNPs) Us-
ing Citrus Peel Extract
Wiyogo P. Wicaksono*, Della Amalia, and LaPfatul Uyun
Department of Chemisty, Faculty of MathemaPcs and Natural Sciences, Universi-
tas Islam Indonesia, Yogyakarta, 55584, Indonesia
*Corresponding author: wiyogo.prio@uii.ac.id
Gold-palladium core-shell nanoparPcles (Au@Pd CSNPs) has been successfully

synthesized through a two-step facile and green method using HAuCl4 precursor
and citrus peel extract (CPE) both as reducing and stabilizing agent. Firstly, a series
of CPE was used to synthesize the core gold nanoparPcle (AuNPs). A|erwards, 100
µL of H2PdCl4 10 mM was employed to produce the Pd shell. The synthesized NPs
was characterized by UV-Vis and Infra-Red (IR) spectroscopy, as well as Transmis-
sion Electron Microscopy (TEM). UV-Vis spectra showed a strong absorbance at
541 nm which indicated the opPmal formaPon of AuNPs using 6 g of CPE, whereas
there was no peak of CPE observed. Furthermore, the formaPon of Au@Pd CSNP
was indicated by the disappearance of the peak at 541 nm. The result from IR
spectroscopy showed OH group from the CPE has a main role in the NPs for-
maPon. TEM image showed a core-shell structure of the Au@Pd CNPs with an 8
nm and 2 nm core diameter and the shell thickness, respecPvely. In conclusion,
this method used the no-cost material, such as citrus peel waste that is very sim-
ple and powerful to synthesize the Au@Pd CNPs.
Keywords: green synthesis, gold-palladium core-shell nanopar=cles, citrus peel

extract
PP06
AnAmicrobial of bacterial cellulose/ZnO/Ag Nanocomposite Membrane
Henry Fonda Aritonang and Olivia Kamea
Physical Chemistry Division, Faculty of MathemaPcs and Natural Sciences, Sam

Ratulangi University, Jalan Kampus Unsrat Kleak, Manado 95115, Indonesia
Email: henryaritonang@yahoo.com
This study is a preliminary study to analyze the anPmicrobial acPvity of the bacteri-
al cellulose/ZnO/Ag nanocomposite membrane. Therefore, various microscopic
and spectroscopic techniques not done. The bacterial cellulose/ZnO/Ag nanocom-
posite membrane has been synthesized by co-precipitaPon method. These were
obtained by immersing bacterial cellulose into Zn(NO3)2.4H2O and AgNO3 soluPon
under basic condiPons. Furthermore, dry nanocomposite membranes were tested
for their anPbacterial acPvity using Gram-negaPve Escherichia coli (E. coli) and
Gram-posiPve Staphylococcus aureus (S. aureus). The nanocomposite membranes
exhibited strong anPmicrobial acPvity against Gram-negaPve and Gram-posiPve
bacteria.
Keywords: Co-precipita=on; Bacterial cellulose/ZnO/Ag; naocomposite membrane;

An=microbial
110
PP07
Extract of Zingiberaceae Leaves Steam DisAllated Residue as AnA-bacterials and
Biofilm Degradator Against Streptococcus mutans
Irmanida Batubara1,2, Dian Yunita1, Irma HerawaA Suparto1,3
1. Department of Chemistry, Bogor Agricultural University, Indonesia

2. Tropical Biopharmaca Research Center, Bogor Agricultural University, Bogor,
Indonesia
Primate Research Center, Bogor Agricultural University, Bogor, Indonesia
Corresponding authors: ime@apps.ipb.ac.id
Zingiberaceae is a family that used to treat various diseases and as spice in

cooking. This research aimed to determine the potency of the extract of
Zingiberaceae leaves steam disPllaPon residue as anP-bacterial and biofilm
degradator against Streptococcus mutans. The disPllaPon residue of Zingiberaceae
leaves (Curcuma longa, Curcuma zeodoaria, Curcuma aeruginosa, Zingiber
officinale, Zingiber cassumunar) was extracted by soxhletaPon method using 3
different solvent namely n-hexane, ethyl acetate, and methanol. AnPbacterial and
biofilm degradaPon assay were performed using microdiluPon technique.
Methanol extract of C. zeodoaria leaves gave the best anPbacterial potency with
minimum inhibitory concentraPon and minimum bactericidal concentraPon value
of 15,63 ppm and good biofilm degradaPon acPvity with inhibitory concentraPon
50% (IC50) of 15,33 ppm. There are 4 spots at thin layer chromatography
bioautogram with spot with Rf 0.90 as the most acPve spot. Terpenoid was
suggested as anPbacterial and biofilm degradaPon group compound.
Keywords: an=bacterial, biofilm degradator, Streptococcus mutans, Zingiberaceae

leaves
PP08
THE EXTRACTION OF ANTHOCYANIN PIGMENT FROM EGGPLANT PEELS (Solanum
melongena L.) AND ITS APPLICATION AS NATURAL ACID INDICATOR
Noor Fitri, Nialita Fitri, Dina Fitriastusi

1
Chemistry Department, Universitas Islam Indonesia, Jl. Kaliurang KM 14.5, Besi,
Sleman, Yogyakarta, Indonesia.
E-mail: noor.fitri@uii.ac.id.
The purpose of this research is to extract the anthocyanin pigment from eggplant
peels which can be used as natural acid indicator. This extracPon was performed by
using two techniques i.e. maceraPon and microwave techniques. The research
steps include sample preparaPon; maceraPon and microwave extracPon using eth-
anol : HCl 1% (2: 1); phenolic compound test; anthocyanin compound test; pH
soluPon test, idenPficaPon using UV-Vis Spectrometer, FTIR and LC-MS / MS as well
as applicaPon of extract eggplant peels as natural acid indicator. The results
showed the yield obtained from eggplant peels extract in maceraPon technique for
48 hours was 3.18% while in microwave technique with Pme variaPon of 3, 5 and 7
minutes were 3.14%, 2.85% and 2.97%. Eggplant peels extract was further idenP-
fied by FTIR and LC-MS / MS. The results of idenPficaPon using FTIR showed the
presence of aliphaPc C-H groups, C = C aromaPcs, and O-H, the group was also pre-
sent in the anthocyanin group. The result of idenPficaPon using LC-MS / MS
showed the presence of two components of anthocyanin group compound with
Delphinidin 3 Glucoside type at retenPon Pme of 3.02 with m/z = 465 and Peonidin
3 Glucoside at retenPon Pme 3.07 with m/z = 463. The qualitaPve test result of
eggplant peels extract showed the existence of phenolic compound marked by col-
or changing into blackish green. The posiPve pH test on the eggplant peels extract
using 1-12 pH soluPon was at pH 3-4. The research showed that eggplant peels ex-
tract can be applied as natural acid indicator at pH 3-4.
Keywords: Anthocyanin, Eggplant peels, Indicator, Macera=on, Microwave, FTIR, LC

-MS/MS
112
PP09
Quality Test of Natural Bath-Soap with Clove Oil and
Its AnAbacterial AcAvity Against Staphylococcus Epidermidis
Sri Handayania, Susila KrisAaningruma, Anna RakhmawaAb, Khulafaurrasidina

a
Department of Chemistry EducaPon, Universitas Negeri Yogyakarta, Indonesia
E-mail address: handayani@uny.ac.id
b
Department of Biology EducaPon, Universitas Negeri Yogyakarta, Indonesia
E-mail address: anna_rakhmawaP@uny.ac.id
Main object of the present work was to use clove oil as an addiPve to make
natural bath-soap as a new approach of herbal cosmePcs and medicine. Product of
natural bath-soap with clove oil was expected to have a good quality based on In-
donesian NaPonal Standart 2016 and effecPve as potenPal anPbacterial agent.
Natural bath-soap was made by saponificaPon reacPon of olive oil, palm oil, vco
and castor oil with aqueus NaOH via cold process methods. SPrring was done unPl
a trace-soap formed at room temperature, then clove oil was added. The mixture
was poured in mold and wait for 2 days unPl solid-soap ready to unmolding. Curing
process was done for 3-4 weeks. AnPbacterial acPvity tests was performed by Kirby
-Bauer diffusion method against Staphylococcus epidermidis. The soap quality as
water content, total fat, insoluble material in ethanol, total free alkali, total chlo-
ride and unsaponificable fat are 1.524%,. 92.052%, 0.8%, 0.0053%, 1.17%, and
0.0038%, respecPvely. The highest inhibitory zone diameter is 22,28 mm on 10%
(m/v) concentraPon at 12 hours incubaPon. Thus, the addiPon of clove oil in natu-
ral bath-soap proved to be effecPvely used as an anPbacterial soap.
Keywords : bath-soap, clove oil, an=bacterial agent

PP10
Waste Management of Integrated Laboratory of Universitas Islam Indonesia (UII)
using AdsorpPon Technique with AcPvated Carbon and CoagulaPon with Poly Alu-
minum Chloride (PAC)
1
Riyanto, 1*Cecep Sa’bana RahmaAllah
1
Islamic University of Indonesia, Yogyakarta
*Email: cecep@uii.ac.id
Study on UII Integrated Laboratory waste treatment by adsorpPon using acPvated

charcoal which is included in PVC pipes or known as system flow has been
conducted. In this method, the waste is returned to the reservoir, then processed
using PAC with a batch system. Waste and PAC are sPrred unPl homogeneous, then
deposited. clear waste is analyzed in accordance with the parameters of
wastewater quality. The results showed that the adsorpPon process using acPvated
carbon with a variaPon of sPrring Pme and weight of PAC was very effecPve. From
the study, it was found that the longer the sPrring Pme and the more acPvated
carbon added, the more effecPve it was to reduce the COD levels in waste, which
was 79.394% with sPrring for 30 minutes and 90.197% by weight of 7 grams of acP-
vated carbon. In the coagulaPon process with Poly Aluminum Chloride (PAC),
wastewater samples are analyzed first for several chemical parameters, especially
heavy metals, before being flowed through the reactor tube. The results of the
analysis show that the integrated laboratory waste samples of UII contain chromi-
um (Cr), lead (Pb) and cadmium (Cd) which are below the criPcal limits set by the
Government of the Republic of Indonesia, so that it can be concluded that the ob-
servaPons in the storage ponds are actually feasible. to the aquaPc environment.
Keywords: laboratory waste, adsorp=on, ac=vated carbon, coagula=on, Poly

Alumunium Chloride
114
PP11
EffecAveness of AcAvated Charcoal from Cassava Skin as Adsorbent of Cu Ion on
Wastewater Integrated Laboratory of the Universitas Islam Indonesia (UII)
Tohari
1
Islamic University of Indonesia, Yogyakarta
*Email: tohari@uii.ac.id
Study of the reducPon of the levels of Cu in the UII Integrated Laboratory

wastewater by adsorpPon method using acPvated charcoal cassava peel has been
conducted. This research was conducted to determine the most opPmum acPva-
tor and concentraPon, the character of funcPonal groups in acPvated charcoal
before and a|er the adsorpPon process, and to find out the amount of Cu ions
which can be adsorbed from laboratory wastewater using acPvated charcoal of
cassava peel. Dry cassava peel is carbonized using a muffle furnace at 400o C for 3
hours. AcPvaPon was carried out chemically using HCl, NaOH and Na2CO3 at 0.2
concentraPons respecPvely; 0.5 and 1 M as much as 50 ml for 24 hours. The most
opPmum acPvator for adsorpPon of Cu ions in laboratory wastewater is HCl at a
concentraPon of 0.5 M with adsorpPon capacity of 90.62%. The funcPonal group
in the acPvated charcoal of cassava skin is –OH, aromaPc C = C, Si-H, Si-O, and the
presence of C = O group from aromaPc acid esters. AcPvated charcoal a|er use for
adsorpPon of Cu ions in laboratory wastewater has a higher% of transmission
compared to acPvated charcoal before adsorpPon
Keywords: charcoal, adsorbent, wastewater

PP12
OpAmizaAon of Zingiber officinale DisAllaAon with Boiled and Modified Methods
Norra Gus Priambodo
Center of EsenPal Oil Study, Universitas Islam Indonesia
One method to get ginger (Zingiber officinale) essenPal oil is disPllaPon. This study
aims to determine the effect of preparaPon and differences disPllaPon methods on
the yield of ginger oil. The disPllaPon methods used are boiled disPllaPon and
modified boiled disPllaPon. Samples of ginger were ground and sliced for 3 kg to
each methods. The disPllaPon process is carried out for 2 hours using maximum
fire from the gas stove. The opPmum results obtained from modified disPllaPon
with milled ginger samples yielded 0.4% yield, oil has a disPncPve ginger smell,
clear yellowish color.
Keywords: boiled dis=lla=on, Zingiber officinale, rendement

116
PP13
Physicochemical EvoluAon of Silica from Salacca Leaves for AdsorpAon
Is FaAmah1*,
1
Chemistry Department, Universitas Islam Indonesia, Kampus Terpadu UII, Jl.
Kaliurang Km 14, Sleman, Yogyakarta, Indonesia 55584
*e-mail: isfaPmah@uii.ac.id
PreparaPon of silica material from Salacca leaves ash has been invesPgated. Silica
was causPc extracted and the physic-chemical characterizaPon was performed by
using x-ray diffracPon (XRD), scanning electron microscope energy dispersive x-ray
(SEM-EDX), and Brunair-Emmet-Teller (BET) gas sorpPon analysis. The result was
applied for salycilic acid adsorpPon. The result showed that silica was obtained with
the specific surface area of about 14.2 m2/g and dominated with silica. It is found
that it is a potenPal performance of silica preparaPon and adsorpPon capability of
the derived material.
PP14
Analysis Of Ferrous Ion Species In Cinnamomum burmanii Leaves As BiosensiAzer
In Iron PhotoreducAon Process Using Fluorocent Light
Johnly Alfreds Rorong 1)* and Adithya YudisAra 2)*

1
)*Professor of Environtmental Chemistry Analysis of MathemaPcs and Natural Sciences
Faculty of Sam Ratulangi University
2
)*Lecturer of Pharmacy of MathemaPcs and Natural Sciences Faculty of Sam Ratulangi
University
rorongjohnly@yahoo.co.id
Analysis of ferrous ion species in agriculture waste extracts of Cinnamomum burmanii

leaves have been conducted using UV-Vis spectrophotometry. Samples were extracted of
cinnamon leaves powder (Cinnamomun burmani) with methanol, ethanol, and ethyl acetate
solvents in 25, 50, and 75%. SoluPon without extract was used as reference sensiPzer and
soluPon without illuminaPon was used as the control. Research has been carried out:
laboratory analysis for maceraPon extracPon, evaporated and dried in the oven.
DeterminaPon of total phenolic, flavonoid and tannin content on cinnamon leaves, with
reagents: Folin Ciocalteu 50%; 2% aluminum chloride in ethanol and vanillin 4% in methanol
and divortex, followed by UV-Vis spectrophotometric analysis at wavelengths; 750; 520 and
415 nm. PhotoreducPon analysis uses a 65 wa2 Fluorosenst light source. The effect of the
extract on Fe3+ photoreducPon can be seen from the formaPon of Fe2+ as a result of the
reducPon of Fe3+ extract a|er being lit for 5 hours, reacted with 2.2 bipyridine 0.07% to
form orange-pink colored complex soluPon, followed by UV-Vis spectrophotometer with
520 nm wavelength.
Cinnamon (Cinnamomun Burmani) leaves extract contains organic material,
phytochemical compounds: Phenolic, Flavonoid and Tanin are rich in electrons so they can
donate one electron to produce biosensiPzer. BiosensiPzers (natural sensiPzers) are
produced because of the Fluorosenst rays from the sun that occur in soil/farmland in the
iron photoreducPon process causing ferric ions to turn into ferrous ions in the iron
photoreducPon process. Plants needed Ferro ions to increase soil ferPlity so that the growth
and development of plants become ferPle.
The results of photoreducPon analysis using 65 wa2 Fluorescent light source for 0,
1, 2, 3, and 5 hours, showed that the concentraPon of iron was reduced as follows for meth-
anol solvent 25%: 1.055; 1.777; 3,888; 9,833; and 9.944 mg / L. Methanol 50% is 1,166; 2;
3.222; 9,055; and 9.277 mg / L. 75% methanol is 1.111; 1,277; 2,388; 8,277; and 8.722 mg /
L. 25% ethanol solvent is 1,111; 1,333; 2,333; 8,833; and 9.055 mg / L. 50% ethanol is 1.611;
1.888; 2,833; 8,333; and 8.5 mg / L. Ethanol 75% is 4,388; 5; 7; 10,888; and 11.722 mg / L.
Acetate ethyl solvent 25%, ie 1,277; 1.777; 3,555; 3,888; and 10.944 mg / L. Ethyl Acetate
50% is 2,555; 3,166; 3,833; 5,388; and 13.388 mg / L. Ethyl Acetate 75% ie 7,222; 7,666; 8.5;
15,556; and 19,888 mg / L. SL is 1.5; 1.444; 1,111; 1.444; and 5,055 mg / L. SWL is 1.5; 1,222;
1,222; 1.944; and 5.888 mg / L.
118
PP15
EmulsificaAon for FormulaAon of Natural Folic Acid Supplements prepared from
Soybean Tempe (Glycine soya L.) and Fermented Spinach (Amarantus sp) for the
Needs of Pregnant Women
YaA MaryaAa), AgusAne SusilowaA, and Aspiyanto

Research Centre for Chemistry, Indonesian InsPtute of Sciences,
452 Building, Kawasan PUSPIPTEK, Serpong - 15314, South Tangerang, BANTEN,
INDONESIA
Corresponding author : maryaP97@yahoo.com
Folic acid naturally can be obtained from vegetables and fruits. RouPne
consumpPon of folic acid for pregnant women before and during pregnancy lowers
neural tube defects (NTDs) risk for infants, spina bifida (anomalies in the spine) and
anencephaly. Folic acid supplements are recommended for the pregnant women,
since it has acPve therapeuPc funcPons prevenPng neural tube defects. The role of
food supplements are to balance nutriPonal food needs of pregnant women. This
study was purposed to invesPgate emulsificaPon process for the formula of natural
folic acid supplementaPon from the mixture of fermented soybean tempe (glycine
soya L.) and spinach (Amarantus sp). RaPo of fermented soybean tempe by Rhizopus
oligosporus C1 and fermented spinach vegetables by kombucha culture was 1:2.5% ;
1:5% ; 1:7,5%, with the addiPon of emulsifier raPo of carboxy methyl celullose and
gelaPn, with concentraPon variaPons (0.2:4) and (0.4:8). The results showed that
the highest levels of folic acid were found in mixed paste preparaPons (1:2.5%) with
0.4% CMC (w/w) with gelaPn at concentraPon of 769.67 g/mL).
Keywords: supplement, folic acid, emulsifier, fermenta=on
PP16
IdenAficaAon of Chemical Content and AcAvity of EssenAal Oil of Citronella
Wangi (Cymbopogon nardus) Against Staphylococcus aureus and Escherichia coli
Bacteria
Dede Sukandar1*, Mirna Tiarani Putri1, Anna Muawanah1, Tarso Rudiana1

1
Program Studi Kimia FST UIN Syarif Hidayatullah Jakarta
Jalan Ir. H. Juanda No 95 Ciputat 15412 Indonesia Telp. (62-21) 7493606
*E-mail: sukandarkimia@uinjkt.ac.id
EssenPal oil of citronella (Cymbopogon nardus) is one of the many essenPal oils
produced in Indonesia that are used as anPbacterial. The purpose of this study was
to determine the essenPal oil content of citronella (Cymbopogan nardus) and to
see anPbacterial acPvity against the growth of Staphylococcus aureus and Esche-
richia coli bacteria. This anPbacterial acPvity test was performed by disc diffusion
method. EssenPal oils (Cymbopogon nardus) have anPbacterial acPvity against
Escherichia coli and Staphylococcus aureus. From the results of the discovery of
components using GC-MS showed that the largest content was 33.86% sitronelal,
geraniol 18.29%, sitronellol 14.97%. EssenPal oils (Cymbopogon nardus) have anP-
bacterial acPvity against Escherichia coli and Staphylococcus aureus. In the diffu-
sion method the concentraPons can inhibit Escherichia coli and Staphylococcus
aureus bacteria at a concentraPon of 700 ppm with moderate inhibitory power. The
citronella essenPal oil has a smaller anPbacterial ability than the chloramphenicol
anPbioPcs.
Keywords : AnPbacterial, Cymbopogan nardus, Escherichia coli, essenPal oil,

Staphylococcus aureus
120
PP17
EfecAvity and CharacterisAc Citronella (Cymbopogon nardus L.)
Oil LoAon as Mosquito Repellent
Iwan Aminudin1, Dede Sukandar1*, Andika Abdika1, SiA NurbayA1, Tarso

Rudiana1,
1
Program Studi Kimia FST UIN Syarif Hidayatullah Jakarta
Jalan Ir. H. Juanda No 95 Ciputat 15412 Indonesia Telp. (62-21) 7493606
*E-mail: sukandarkimia@uinjkt.ac.id
Repellent is a material that has the ability to protect humans from mosquito
bites when applied to the surfaces of the skin. One of the natural ingredients
that has the potenPal as a repellent is the citronella (Cymbopogon nardus L) with
sitronellol and geraniol as the main compounds. Lemon grass oil is formulated
into a loPon preparaPon with concentraPon variaPons of 0.5%, 1%, 1.5%. the
purpose of this research is to make citronella oil loPon and test the characteris-
Pcs, stability, and protecPon against mosquito bites. LoPon formula is then test-
ed by measuring the stability of pH, color, texture, aroma, and consistency. Effec-
Pveness test is done through protecPon power test by using alive mosquito di-
rectly. The result of this study shows that all of the three formulas of citronella
oil loPon have sensory characters with good color, aroma, texture, and con-
sistency. The stability of resulPng loPon is homogeneous and has a pH in the
range of 7-8 and has an acceptance level above 60% in the organolepPc test. The
loPon formula with a concentraPon of 1.5% has 50% mosquito bite protecPon
for 6 hours of tesPng Pme. The formula also does not have an irritaPng effect.
Kata kunci : Repellent, Citronella Oil, Mosquito, Lo=on.

PP18
AnAbacterial AcAvity Test of Klebsiella pneumonia from Tomato Fruit Extract
(Solanum lycopersicum L.) as a prevenAon of Pneumonia
Habibi Hidayat1,a) Rostyanesia1) Yashinta Suci K1) Vania Amanda2)
1
Department of Chemistry, Faculty of Mathema=cs and Natural Sciences, Universi-
tas Islam Indonesia
Jl. Kaliurang KM 14.5, Sleman, Yogyakarta, Indonesia, 55584
2
Universitas Ahmad Dahlan Hospital
Jl. Cendelaras Raya, Karangsari,Wedomartani, Ngemplak, Sleman, Yogyakarta, In-
donesia, 55584
a)
Corresponding author:habibihidayat13@uii.ac.id
Tomato is a fruit that a lot of spread in almost every region in the archipelago and
has a high nutriPonal value. The process of isolaPon and idenPficaPon of tomato
extracts has been done. FermentaPon process from tomato fruit for each fermenta-
Pon Pme and obtained pH range as many as 5.0 and 4.0. The idenPficaPon mor-
phology of bacteria for each T36 and T48 samples were shaped bacil and posiPve
Gram, don’t have spores and colonize and then, the samples is done to acid re-
sistance test at pH 2.0 unPl pH 6.0 and obtained for each T36 and T48 samples having
resistance at pH 4.0 and 3.0. So that, the samples sPll able to survive in an acid con-
diPon. A|er that, all of the samples is done to anPbacterial acPvity test with using
Mueller Hinton and Agar nutrient medium into petridish. The process of acPvity
test that carried out for 3 days using anPbioPc as control like an ampicillin and
erythromycin when using Klebsiella pneumonia as test bacterial obtained clear zone
value from T36 sample respecPvely as many as 7 mm, 10 mm and 11 mm while T48
sample as many as 17 mm, 17 mm and 18 mm. So, the conclude that tomato fruit
extract having ability as anPbacterial against Klebsiella pneumonia bacteria in an
effort to prevenPon of pneumonia.
Keyword : An=bakteri, Klebsiella Pneumonia, Tomat, Pneumonia

122
PP19
ANTIBACTERIAL ACTIVITY OF SOME Extracts
COCOR BEBEK LEAF (Kalanchoe millo(i)
Lilis Si( Aisyah1, Yenny Febriani Yun1, Fariha1, Issana Pramordha Wardhani1,
Nurhabibah Alawiyah1, Dewi Melia( Agus(ni1,Sari Purbaya1, Unang Suprat-
man2 , Yoshihito Shiono3
1
Department of Chemistry, Faculty of Sciences and InformaPcs, Jenderal Achmad
Yani University, Cimahi 40528
2
Natural Product Chemistry Group, Department of Chemistry, Faculty of Mathe-
maPcs and Natural Sciences, Padjadjaran University, Bandung-Sumedang Km 21,
JaPnangor, Sumedang 45363
3
Department of Food, Life, and Environmental Science, Faculty of Agriculture,
Yamagata University, Tsuruoka, Yamagata 997-8555, Japan
*Correspondent author : lies.syarifudin@lecture.unjani.ac.id
Cocor bebek (Kalanchoe millo=i), is one species of Kalanchoe that is tradi=onally

used to treat several diseases, one of which is an=bacterial. This study aims to ex-
amine the an=bacterial ac=vity of n-hexane extract, methylene chloride, ethyl ace-
tate, and K. millo=i leaf ethanol against Staphylococcus aureus, Bacillus sub=lis,
Escherichia coli and Salmonella typhimurium, using liquid microdilu=on method.
The results showed that the an=bacterial ac=vity of n-hexane extract was ac=ve
against S. thypimurium bacteria by giving MIC and KBM values of 7.8 μg / mL and
15.7 μg / mL; methylene chloride extract, ac=ve against B. sub=lis by giving MIC
and KBM values of 7.8 μg / mL and 62.5 μg / mL; ethyl acetate extract, ac=ve
against S. aureus, E. coli and S. typhimurium by giving MIC and KBM values of 3.9
μg / mL and 15.7 μg / mL, and ethanol extract, ac=ve against S. aureus bacteria
and E. coli gave MIC and KBM values of 7.8 μg / mL and 62.5 μg / mL. The results
showed that K. millo= leaves could poten=ally be used as an an=bacterial.
Keywords: K.millo=i, extract, an=bacterial ac=vity, MIC, MBC
PP20
Phytochemical and BioacAvity of Ethanol Extract of Cauliflower
(Brassica Oleracea Var. BotryAs)
Fri RahmawaA1, Antonio August Indra Tjiarwana2, Maria Bintang1,3

1
Departement of Biochemistry, Faculty of Medicine, Universitas Kristen Indonesia,
Indonesia
2
Student of Faculty of Medicine, Universitas Kristen Indonesia, Indonesia
3
Departement of Biochemistry, Faculty of MathemaPcs and Natural Sciences, Bogor
Agricultural University, Indonesia
*Corresponding Author: fri_rahmawaP@yahoo.co.id
AnPoxidants are compounds that can inhibit the reacPon of free radicals in the
body. This study aims to determine the phytochemical content of cauliflower by the
Harbone method, the anPoxidant acPvity with DPPH (2,2-diphenyl-1-pikril hidrazil)
method and toxicity test by the BSLT (Brine Shrimp Lethality Test) method of
cauliflower extract (Brassica oleracea var. BotryPs). Cauliflower extract was made
using maceraPon extracPon method with ethanol solvent p.a. The results showed
that the phytochemical test of cauliflower containing alkaloids, glycosides, steroid,
triterpenoids, flavonoids, and saponins. The IC50 value of cauliflower ethanol extract
was 292.26 ppm and LC50 677.95 ppm. While the IC50 value of vitamin C is 6.733
ppm. This value shows cauliflower has weak anPoxidant acPvity, but at IC50
concentraPon is not toxic to shrimp larvae.
Keywords: An=oxidants, BSLT, Cauliflower, DPPH, phytochemical

124
of PhylogeneAc MSP 1 Papua and Sumba,

N
Euniche R.P.F. 1, Y.P. and Evie L. i
123Biology Faculty of Math and Sciences, U ive si y of

e e w si , Kampus UNCEN Waena, Kamp Papua,
esi
is an endemic disease in almost all egi s of NTT and Papua.

l i is caused by the that lives
and develops in human l . of and
has made this disease o e difficult to
against caused by P. in Sumba
(NTT) is quite high, handling can be done with a cci i
GenePc change can due to fusion of gametes
and also ce GenePc
in genePc ive si y of . specifically to
the highly anPgenic e ozoi e o ei ( e ozoi e /
MSP1). that in the gene that encode this ei si
e e es si le for invasion and abiliPes of P.
se on 10 blood samples of paPents in Public Hospital,
the MSP1 allele g found at 1049 bp. The allele of MSP 1
at the same 1 locus. e with a sample
data of MSP 1 Sumba Bes , NTT e of alleles at 3 loci.
Key Plasmodium falciparum, MSP1 Jayapura, Malaria Tropica

PP22
DeterminaAon EncapsulaAon Efficiency Beta Carotene and Vitamin C In Liposomes
of Coconut Phospholipids (Cocos Nucifera L.) Choline Species
Dwi HudiyanP1, a), Marliana JayanP2, and Khairul Anam1
1
Chemistry Department, Diponegoro University, Semarang, Indonesia
2
Undergraduate Program, Chemistry Department, Diponegoro University, Sema-
rang, Indonesia
a)
Corresponding author: dwi.hudiyanP@live.undip.ac.id
Abstract. In this research, coconut phospholipid (Cocos nucifera L.) choline

species or phosphaPdylcholine (PC) were used as liposomes making materials.
Coconut PC liposomes are used to encapsulate beta carotene and vitamin C.
The stability of liposomes can be increased by adding 10% cholesterol in lipo-
somes. The efficiency of beta carotene and vitamin C encapsulaPon in lipo-
somes of coconut phospholipid (Cocos nucifera L.) choline species was 58.79%
and 63.15%. The addiPon of 10% cholesterol increased encapsulaPon efficiency
vitamin C in liposome of coconut phospholipid (Cocos nucifera L.) choline spe-
cies by 75.61%, while the beta carotene encapsulaPon efficiency in liposomes
of cocos phospholipid (Cocos nucifera L.) choline species decreased to amount-
ed to 55.99%.
Keyword : Beta carotene, Vitamin C, Encapsula=on Efficiency
126
PP23
InhibiAng of InteracAon between E-Cadherin E-Cadherin Protein by Cyclic PepAde ADTC4

(Ac-CDDTPC-NH2) Inhibitor Simulated on 120 ns
Parsaoran Siahaan1*, Rikno Budiyanto1, Vivitri Dewi Prasasty2, Dwi HudiyanA1,

1
Departement of Chemistry, Faculty of Science and MathemaPcs, Diponegoro University
2
Faculty of Biotechnology, Atma Jaya Catholic University of Indonesia
*Corresponding author, tel/fax: 0813-1055-3498,
email : siahaan.parsaoran@live.undip.ac.id; siahaan_parsaoran@yahoo.com
ModulaPng on molecular level of molecular and binding conformaPon between protein

molecules was able to change the acPvity of protein on the cell. This principle was applied
for developing the pepPde for diagnosPc and therapeuPc purposes. On the molecular level,
molecular docking computaPonal methods have been widely used for understanding the
mechanism of modulaPng of those conformaPon changes. The treatment of diseases on the
central nervous system cell which is blocked by E-Cadherin of Pght juncPons can be
overcame by modulaPng approach. By modulaPng, the molecules that have a BM more
than 500 D and more than 11 Å in diameter are predicted able to pass. Experimentally, the
ADTC4 pepPde which is a E-cadherin-derived pepPde was able to modulate the E-
cadherin...E-cadherin interacPon of Pght juncPons. The ADTC4 pepPde can induce and
increasing the porosity of Pght juncPon in BBB. On molecular level, the increased porosity
predicted because of the inhibiPng of interacPon between E-cadherin...E-cadherin pepPdes
by modulator or blocker of ADTC4 pepPde. However, the mechanism of ADTC4 pepPde to
inhibite the E-cadherin...E-cadherin interacPons have not been widely understand and
studied. In order to explain the experimental results molecularly, the molecular docking
methods have been applied. In this study molecular docking modeling have been carried
out to determine the binding energy and binding site between ADTC4 cyclic pepPde with E-
cadherin. At the first of stage was the opPmaPon of the linear and cyclic ADTC4 pepPde by
molecular dynamics using GROMACS so|ware. At the second stage, the molecular docking
was carried out to determine the lowest binding energy between one linear and 20
structure of cyclic ADTC4 and E-cadherin EC1-EC2 domain using Autodock so|ware. The
A18 conformaPon which have the binding energy -28.24 kJmol-1 was the greatest inhibitor.
The binding sites was at the residues Trp2, Val3, Ile4, Gln23, Ile24, Lys25, Ser26, Asn27 and
Met92 in the adhesion-arm acceptor pocket region of Pght juncPon.
PP24
ANTIOXIDANT ACTIVITY FROM METABOLITE OF Carica papaya ENDOPHYTIC
BACTERIA
PurbowaAningrum R Sarjono, Nies S Mulyani, Dewi Kusrini, Ngadiwiyana,
Ismiyarto, Qisthy HanifaA Hazrina
Chemistry Departement of Diponegoro University,

Jl. Prof. Soedarto, Tembalang, Semarang 50275
email: purbowaPning@live.undip.ac.id
One source of anPoxidant compounds are secondary metabolites which can be

obtained from the leave of papaya (Carica papaya). The secondary metabolites
can be isolated from plants and endophyPc bacteria that is symbioPc with papaya
plants. The endophyPc microbacteria have many advantages in produce bioacPve
compound. This study aims to isolate the endophyPc microbes that is symbioPc
with papaya, obtaining data of anPoxidant acPvity with DPPH method and
obtaining phytochemical screening qualitaPve data of secondary metabolites
producPon of the endophyPc bacteria.The results from this study is one isolate
endophyPc bacteria that is symbioPc with papaya leave. Obtained bacterial isolate
has staphylococcus shape and is a type of gram-negaPve bacteria. The anPoxidant
acPvity of secondary metabolites of endophyPc bacteria isolate using DPPH
method has IC50 of 22.472 ppm. Phytochemical screening shows that the
producPon of secondary metabolites of endophyPc bacteria which were isolated
from papaya leave contains alkaloids, flavonoids, tannins and saponins.
Keyword : papaya leave, DPPH, an=oxidant ac=vity, endophy=c bacteria

128
PP25
AdsorpAon of Eosin Y Dyes Using Modified Silica Gel Composites
3-aminopropyltriethoxysilane (APTES) - AcAve Carbon from Natural Resources
Yusmaniar1Ahmad Nubail1 , Arif Rahman1

1
Universitas Negeri Jakarta,
Jl. Rawamangun Muka 13220, Jakarta, Indonesia
Corresponding Author: yusmaniarl@unj.ac.id.com
Eosin Y dye have been successfully tested on adsorpPon using silica gel, acPvated
carbon, and composite adsorbent. IniPal effect on pH and contact Pme showed
that the adsorbents are on pH 4 and 30 minute, respecPvely. The isotherm
adsorpPon model of eosin Y toward silica gel composite modified by APTES –
acPvated carbon following the Langmuir isotherm with maximum adsorpPon
capacity and Langmuir constant value are 21,28 mg g-1 and 0,165, respecPvely.
Keywords: Adsorp=on, Eosin Y, Rice Husk Ash, Coconut Shell, Ac=vated Carbon,
Silica Gel, APTES, Composite
PP26
ANALYSIS OF STUDENTS AUTHENTIC ASSESSMENT IN CHEMISTRY
THROUGH FLIPPED CLASSROOM MODEL
Maria ParisAowaA1*, TriAyatma H1., SeAa Budi1, Tamia AgusAna1

1
Department of Chemistry EducaPon, Universitas Negeri Jakarta
*
e-mail: maria.parisPowaP@unj.ac.id
This study aims to determine the results of authenPc assessment of students that
include cogniPve, affecPve and psychomotor aspects during acid-base learning
process using flipped classroom model. The qualitaPve method was used in this
study with data collecPon techniques through learning outcome tests for cogniPve
aspects, observaPon for assessment of affecPve and psychomotor aspects, and
quesPonnaires. Flipped classroom model is done by combining 50% of acPviPes in
the classroom and 50% of acPviPes outside the classroom. The learning process
uses four learning videos consist of two videos about the concept of acid-base and
two video experiments on acid-base. The results showed that student learning
outcomes increased on cogniPve aspects. It is supported by changes in affecPve
and psychomotor aspects during the learning process. The average score of stu-
dents in each indicator of affecPve and psychomotor aspects has increased. It can
be concluded that flipped classroom model can be used to improve student learn-
ing outcomes on cogniPve, affecPve and psychomotor aspects.
Keywords: flipped classroom, authen=c assessment, cogni=ve, affec=ve, psycho-

motor
130
PP27
THE SYNTHESIS OF 2'-HYDROXY-4-METHOXYCHALCONE, 4'-METHOXYLAVONE, 2'-HYDROXY

-4-CHLOROCHALCONE AND 4'-CLOROFLAVANONOL AND THEIR IN VITRO ACTIVITY TEST
Winarto Haryadi1 , Sabirin Matsjeh1, EA Nurwening Sholehah2, SrinofianA Sihura1

1
Department of Chemistry, Faculty of MathemaPcs and Natural Sciences, Universitas Gadjah
Mada, Yogyakarta, Indonesia
2
Department of Pharmacology and Therapy, Faculty of Medicine, Universitas Gadjah Mada,
Yogyakarta, Indonesia
Coresponding author: Email wnrt_haryadi@ugm.ac.id
The synthesis of 2'-hydroxy-4-methoxychalcone, 4'-methoxyflavone, 2'-hydroxy -4-

chlorochalcone and 4'-chloroflavanonol and cytotoxicity acPvity test to HeLa, WiDr, T47D,
MCF7 and Vero cells were performed. Chalcone is synthesized by reacPon between 2-
hydroxyacetophenone and 4-methoxybenzaldehyde and 4-chlorobenzaldehyde with NaOH
catalyst in ethanol solvent. The reacPon product is separated and refined. Then 2'-hydroxy-4-
chlorokhalkon is reacted with acePc acid anhydride in the ethylacetate solvent and the Na-
HCO3 catalyst to produce 2'-acetyl chalcone. The resulPng 2'-acetylchloride was oxidized
through Algar-Flynn-Oyamada reacPon and undergoing β-cyclizaPon process to form 4'-
chloroflavanonol.
The results of the analysis using the UV-Vis spectrometer, FT-IR, GC-MS, 1H-, 13C-
NMR showed the resulPng compounds according to 2'-hydroxy-4-methoxycha, 4'-
methoxiflavone, 2'-hydroxy-4-chlorochalkone and 4'-chloroflavanonol. The cytotoxic acPvity
test of 2'-hydroxy-4-methoxyrous, 4'-methoxiflavone, 2'-hydroxy-4-chlorochlaine and 4'-
chloroflavanonol in vitro against HeLa, T47D, WiDr and Vero cells denotes chalcone ie 2'-
hydroxy -4-methoxyethylene and 2'-hydroxy-4-chlorochalcone provide IC50 values
successively 9, 10, 12, 76 gmL-1 and 20, 33, 21, 149 gmL-1. While 4'-methoxylavone and
4'-chloroflavanonol gave IC50 values respecPvely 468, 318, 400 g/mL and 353, 55, 4. 10 +
4 ,, 4. 10 + 4 g/mL. The IC50 value data above shows that the 2'-hydroxy-4-methoxylate
compound exhibits highly acPve cancer cell growth (HeLa), breast cells (T47D) and colon
(WiDr), while 2'-hydroxy-4- chloroquin show very acPve cell-cell growth against uterine
(HeLa) and colon (WiDr) cells but is quite acPve against breast cells. 4'-methoxiflavone com-
pounds are inacPvated to the growth of cancer cells HeLa, T47D and WiDr while 4'-
chloroflavanonol is only acPve enough against T47D cells.
PP28
Phytochemical and anAoxidant ACTIVITIES IN EXTRACT n-hexan, Ethyl Acetat and

Methanol SKIN BTANG Chisoceton sp.(Meliaceae)
Dewa Gede Katja
Chemistry Department, Universitas Sam Ratulangi Manado
Email : dewakatja@yahoo.com
Abstract
This study aims to determine the class of secondary metabolites, compounds and
anPoxidant acPvity of each extract of the bark of Chisocheton sp. (Meliaceae). The
extracPon of 40 g of powdered bark Chisocheton sp (Meliaceae) with n-hexan,
ethyl acetate and methanol each with 2000ml (3x2000mL) successively produced 8
g of n-hexan ekstrat concentrated, 5.2 g of concentrated ethyl acetate extract and
6.7 g of concentrated methanol extract. Phytochemical test results indicate the
presence of compounds of flavonoids, terpenoids, steroids and phenols. The test
results of anPoxidant acPvity with DPPH method showed that the ethyl acetate
extract gives IC50 value of 22 ppm less than the IC50 vitamin C at 22 ppm, which
means ethyl acetate extract had the greatest ability to capture free radicals.
Keywords: Chisocheton. sp, terpenoids, flavonoids, steroids, phenols, DPPH and

phytochemicals.
132
PP29
Mechanical and Chemical CharacterisAc of Edible Film From Carrageenan Based

Red Seaweed (Euchema sp.) From Biak with Sorbitol as PlasAsizer
Wahyuni K. Dewi1, Agnes E. Maryuni2, SepAani Mangiwa3

1,2
Program Studi Kimia Jurusan Kimia, Fakultas MIPA Universitas Cenderawasih, Ja-
yapura,
Kampus UNCEN Waena, Jl. Perumnas III Waena- Jayapura 99358
Korespondensi: Wahyuni K. Dewi
Email: wahyuniadewi22@gmail.com
The aim of this research was to characterize the mechanical and chemical proper-
Pes of the carrageenan based edible film. Edible film made by blending method.
Carrageenan was mixed with sorbitol with carrageenan concentraPon 0.6;0.8;1;1.2
and 2%. Variable analyzed were tensile strength , elongaPon at break and FTIR.
Research showed that the best mechanical characterisPcs was resulted from edible
film made from 2% carrageenan, with tensile strength 39,168 Mpa and elongaPon
at break 41,533%. FTRI analysis showed thar the addiPon of sorbitol caused the
decreasing of internal hydrogen bonding between polimer in the matrix.

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Interna(onal Conference of The Indonesian Chemical Society

Interna(onal Conference of The Indonesian Chemical Society

On behalf of the conference organizing commi2ee, we are happy to pre-

The aim of the ICICS 2018 is to promote interdisciplinary researches in

Finally, we would like to express our graPtude to Rector of University of

Jayapura, September 26, 2018

Organizing Committee Members

Dr. Frans A. Asmuruf SepAani Mangiwa, M.Si

Organizing Committee Members

Jayapura City Sentani Lake

THE GRAND ABE HOTEL

LOVE LAKE HOLTEKAM BEACH

BORDER HAMADI TRADITIONAL ART MARKET

Good morning and May Good be with us

Hereby, on behalf of the Organizing Commi2ee, I acknowledge Prof. Nishi-

OPENING REMARKS FROM RECTOR

DisPnguished guests, ladies and gentlemen,

Thank you and have a nice conference

THE 7th INTERNATIONAL CONFERENCE OF THE INDONESIAN CHEMICAL SOCIETY

09.15-09.20 Speech by Chair of the Indonesian Chemical Society

09.20-09.25 Papua TradiPonal Dance Performance

09.45-10.15 PLENARY SESSION 1.

Prof. Dr. Supa Honnangbua

Moderator: Yohanis Irenius Mandik, Ph.D

Tatas H.P. Brotosudharmo, Dipl. Chem., Ph.D

Moderator: Yane O Ansanay, Ph.D

10.45-10.50 Papua TradiPonal Dance Performance

10.50-11.20 PLENARY SESSION 3.

Prof. Dr. Piyarat Boonsawang

Moderator: Yohanis Irenius Mandik, Ph.D

Dr. Frans Asmuruf

Moderator: Octolia Togibasa, Ph.D

Nishigaki M. Toshiaki, Ph.D

Moderator: Maria Simonapendi, M.Si.

13.20-14.50 PARALLEL SESION 1

15.00-17.00 PARALLEL SESION 2

17.00-17.15 The best Oral Presenter announcement

18.30-ﬁnish Closing ceremony and Gala Dinner Hosted by Mayor of Jayapura

Closing ceremony and Gala Dinner Schedule

ORAL PRESENTATION SCHEDULE

ORGANIC CHEMISTRY & EDUCATION OF CHEMISTRY

No. Time Code Presenter Title

6. 14.00- OP04 Meiske Sangi DeterminaPon of Total Phenolic Content

No. Time Code Presenter Title

8. 14.30- OP07 Eﬀendi Development of Basic Chemical Module of

9. 14.45- OP08 Florida Do- ReconstrucPon of Basic Chemistry Modul

10. 15.00- OP09 Daniel Synthesis of 0-Carboxymethyl N-Palmitoil

14. 15.50- OP14 Supriatno Cytotoxic Limonoids from The Stembark of

INORGANIC CHEMISTRY & PHYSICAL CHEMISTRY

No. Time Code Presenter Title

3. 14.00- OP15 Ilham Salim TransesteriﬁcaPon of Used Cooking Oil

6. 14.30- OP18 Lukman Atmaja Pva/Chitosan-Montmorillonite Compo-

No. Time Code Presenter Title

9 15.20- OP22 Gesyth MuPara PreparaPon of Metal (ni,co)mo on sup-

11. 15.40- OP24 IrdhawaP Anodic Stripping Voltametri for Determi-

14. 16.10- OP27 Rurini Study The Inﬂuence of DisPllaPonTime

ANALYTIC AND ENVIROMENTAL CHEMISTRY

No. Time Code Presenter Title

13.30- IS05 Yusthinus Mercury ContaminaPon from ArPsanal Gold

4. 14.20- OP31 P de Rozari An InvesPgaPon Into The Use of Sand Media