Cidofovir is an antiviral drug used to treat CMV retinitis in AIDS patients. It works by interfering with the DNA synthesis of CMV, inhibiting viral replication. It has serious potential adverse effects including kidney damage, low white blood cell count, fever, nausea, vomiting, and vision changes. Nurses must closely monitor patients for these adverse effects and educate patients about reporting any side effects or changes in vision immediately.
Cidofovir is an antiviral drug used to treat CMV retinitis in AIDS patients. It works by interfering with the DNA synthesis of CMV, inhibiting viral replication. It has serious potential adverse effects including kidney damage, low white blood cell count, fever, nausea, vomiting, and vision changes. Nurses must closely monitor patients for these adverse effects and educate patients about reporting any side effects or changes in vision immediately.
Cidofovir is an antiviral drug used to treat CMV retinitis in AIDS patients. It works by interfering with the DNA synthesis of CMV, inhibiting viral replication. It has serious potential adverse effects including kidney damage, low white blood cell count, fever, nausea, vomiting, and vision changes. Nurses must closely monitor patients for these adverse effects and educate patients about reporting any side effects or changes in vision immediately.
Cidofovir is an antiviral drug used to treat CMV retinitis in AIDS patients. It works by interfering with the DNA synthesis of CMV, inhibiting viral replication. It has serious potential adverse effects including kidney damage, low white blood cell count, fever, nausea, vomiting, and vision changes. Nurses must closely monitor patients for these adverse effects and educate patients about reporting any side effects or changes in vision immediately.
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DRUG STUDY: NCM 106 PHARMACOLOGY Instructor: _______________________________________ Date: ________________________
NAME: ____________________________________________________________ BLOCK and Year:___________________________Group: ______________________________
DRUG NAME MECHANISM OF INDICATION CONTRAINDICATION ADVERSE EFFECTS NURSING INTERVENTIONS
ACTION Generic Name: Exerts antiviral effect CMV retinitis in AIDS Hypersensitivity to drug, CNS: headache, seizures, Patient monitoring: cidofovir by interfering with patients probenecid, or other sulfa- coma Assess white blood cell DNA synthesis of containing agents EENT: decreased count and creatinine and CMV, thereby Creatininelevelabove1.5mg/ intraocular pressure urine protein levels inhibiting viral dl, calculated creatinine GI: nausea, vomiting, within 48 hours of each replication diarrhea, anorexia, oral dose. clearance of 55 ml/ minute candidiasis Drug Classification: or less, or urine protein Closely monitor GU: proteinuria, Antiviral level of 100 mg/dl or higher nephrotoxicity intraocular pressure and Concurrent use of Hematologic: neutropenia visual acuity. nephrotoxic drugs Hepatic: hepatomegaly Monitor hepatic enzyme Metabolic: metabolic levels in patients with acidosis hepatic disease. Musculoskeletal: muscle contractions Patient teaching: Available Dosage: Respiratory: dyspnea, Tell patient to CMV retinitis in increased cough immediately report AIDS patients Skin: rash, alopecia fever, vision Adults: 5 mg/kg I.V. Other: pain, fever, chills, changes, nausea, infused over 1 hour infection, pain at I.V. site vomiting, rash, or q week for 2 urinary output continuous weeks; changes. then 5 mg/kg I.V. Instruct patient to once q 2 weeks as a take probenecid, as maintenance dose prescribed, before each dose and to have regular eye examinations. Urge female patient of childbearing age to use effective contraception during and for 1 month after therapy. Instruct male patients to use barrier contraception during and for 3 months after therapy. As appropriate, review all other significant and life- threatening adverse reactions and interactions, especially those related to the drugs and tests mentioned above.