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Lec - 4 Plant Sources of Nutraceuticals

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Lec – 4 Plant sources of Nutraceuticals

Nutraceuticals are considered as a components of traditional and non traditional foods that have the
benefits of human health.

The substances may

(1) be part of an intact food source, such as the lycopene - in a tomato

(2) be part of a processed food, such as lycopene from tomatoes in the recipe of ketchup and sauce.

(3) be a fortified or enriched substance in a food, such as lycopene added to a other fruit juice

(4) Be provided in supplemental form.

Sources of Nutraceuticals:

Nutraceuticals : components of plants, animals, yeast, and fungi as well as bacteria. These are termed as
: Phytochmicals (flavanoids), Zoochemicals (conjugated linoleicacid), Fungochemicals (cyclosporin) and
Bacteriochemicals (epothilone-D)

Examples of Nutraceuticals Substances grouped by food sources

Plants Sources
β-Glucan Nordihydrocapsaicin
• Ascorbicacid • Zeaxanthin
• Tocotrienol • Allicin
• Quercetin • d-Limonene
• Luteolin • Genestein
• Cellulose • Lycopene
• Lutein • Hemicellulose
• Gallicacid • Lignin
• Perillylalcohol • Capsaicin
• Indole-3 • Geraniol
• Carbonol • β–Ionone
• Pectin • α-Tocopherol
• Daidzein • β–Carotene
• Glutathione • Selenium
Examples of foods that have higher content of specific nutraceutical substances

Nutraceuticals substances Foods of remarkably high content


Carnosol Rosemary
Catechins Teas , berries
Adenosine Garlic, onion
Indoles Cabbage, broccoli, cauliflower, kale, Brussel
sprouts
Curcumin Turmeric
Ellagic acid Grapes, strawberries, raspberries, walnuts
Anthocyanates Red wine
3-n-Butylphthalide Celery
Cellulose Most plants(component of cell walls)
Pectins Most plants(in fruits)

List of some common chemical compounds isolated from plants used as Nutraceuticals.

Chemical compounds Source Properties


Allicin from Allium sativum l. It is a powerful antifungal antibacterial.
It has been shown to be an antioxidant and has been used to
treat arteriosclerosis and serum cholesterol
Betaine (Trimethyl Glycine) Reduces toxic buildup of homocysteine.(Associated with
from green leafy vegetables arteriosclerosis and clots)
and germinated grains Elevated level is due to impairment of methionine to cysteine.
Bromelain from Ananas sp. It is pineapple protease enzyme used to prevent heart
disease, reduce the effects of aging, improve the immune
system, and to reduce arthritis and inflammation
Camphor from Cinnamomum Used as an inhalant to treat cold and flu.
Capsaicin or trans-8-methylN- Used for pain relief topically and as a digestive aid when taken
vanillyl-5 nonenamide from internally. It is also seen as a possible antioxidant for the body.
Capsicum annum
Carnitine ( amino acids) or Responsible for the transportation of long-chain fatty acids
L-Carnitine from Asparagus groups into the mitochondria. To be oxidized to produce
energy(Deficiency reduces energy production)
Ellagic Acid from strawberries this phytochemical fights cancer in humans.
and raspberries
Ricinoleic acid from Castor OilCastor oil is used both externally (multiple skin problems) and
or Ricinus communis internally for constipation, upper respiratory problems, and
liver and kidney issues.
Chocolate ( a mixture of cocoa Have positive effects on the heart and blood pressure due to
obtained from Theobroma the flavonoids in chocolate. Chocolate also contains a
cacao and vanilla from orchid) neurotransmitter, serotonin, that acts as an antidepressant,
and other substances, such as theobromine and
phenylethylamine. These have a stimulating effect.
Curcumin, desmethoxy Antimicrobial activity
curcumin, bisdesmethoxy The colorant in turmeric a fraction of which has been shown by
curcumin from Curcuma studies done at the University of California in Los Angeles to
longa clear brain plaque caused by Alzheimer's disease.
Plant Glucosamine Chondroitin and glucosamine are part of normal cartilage and
acts as a cushion between the joints.
Glutathione (GSH) from A tripeptide, which provides antioxidant properties thereby
cruciferous vegetables protecting the cells against damage by free radicals.
Hesperidin (flavanoids) from Hesperitin is a GRAS ingredient that shows interest as a
citrus-lemon grapes oranges potential antioxidant and antimicrobial properties.
before they ripen
Hydroxy Citric Acid (HCA) from It inhibits Adenosine triphosphate citrate lyase ( enzyme
Garcinia Cambogia & responsible fatty acid synthesis)and has been used in the
Hibiscus sabdariffa treatment of obesity.
Isoquercitin from mangoes Increases blood flow for varicose veins, and possible use for
arterial flow as well.
Recent studies have shown possibilities in increased brain
functions and it might be useful in the treatment of
progressive Alzheimer's disease.
Licorice or Glycirrhizic acid Licorice has been used as early as Roman and Greek times as a
from the root of Glycyrrhiza decongestant, antiinflammatory, to treat stomach ulcers..
glabra ( Adhimathuram)
Lignan from rye , soybean and Lignans are one of the two major classes of phytoestrogens.
brocooli Phytoestrogens are antioxidants and have been viewed as
reducing ill effects in the body as cellular destruction, aging,
etc.
Lutein and Lutein Esters from it is a carotenoid which shows healthful eye benefits.
marigold , seeds, and also
found in spinach, rosemary
and kale,
Zeaxanthin- is the coloring A carotenoid used as an antioxidant.
agent in marigolds and is It is used for eye health and some claim will retard the effect
extracted from them of 'aging eyesight' or Age-Related Macular Degeneration
(AMD).

Phenolic constituents as nutraceuticals from different fruit residues

Fruit Phenolic Waste Residue Constituent


Apple Peel and pomace  Epicatechin,
 catechins,
 hydroxycinnamates,
 phloretin glycosides,
 quercitin glycosides, procyanidins,
 chlorogenic acid, anthocyanins
 Cinnamic acid,
 coumaric acid,
 caffeic acid,
 ferulic acid,
 chlorogenic acid,
 neochlorogenic acid, 
Grapes Seed and skin  p-hydroxybenzoic acid,
 protocatechuic acid,
 vanillic acid,
 gallic acid,
 proanthocyanidins,
 quercetin 3-O-gluuronide,
 quercetin, resvaratrol, pullulan
Citrus Peel Hesperidin, naringin, eriocitrin, narirutin
Gallocatechin, anthocyanins, delphindin,
Banana Peel
cyaniding, catecholamine
Cyanidin-3-glucosides, cyanidin-3-
Litchi Pericarp, seeds rutonoside, malvidin-3-glucoside, gallic
acid, epicatechin-3-gallate
Gallic acid, ellagic acid, gallates,
Mango Kernel
gallotannins, condensed tannins

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