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Gujarat Technological University

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Seat No.: ________ Enrolment No.

_________
GUJARAT TECHNOLOGICAL UNIVERSITY
BPHARM – SEMESTER II • EXAMINATION – SUMMER • 2014
Subject code: 220003 Date: 30-05-2014
Subject Name: Pharm Chemistry II
Time: 02:30 pm to 05:30 pm Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Explain following terms: (Any Six) 4. Phosphorescence 06


1. Adsorption 5. Dipole moment
2. Parachore 6. Optical rotation
3. Radioactivity 7. Conductance
(b) State and explain Henry’s law. 05
(c) Differentiate following: 1. Homogeneous and Heterogeneous catalysis 05
2. First order reaction and second order reaction

Q.2 (a) Explain Langmuir and Gibb’s adsorption isotherm. 06


(b) Discuss pharmaceutical applications of adsorption. 05
(c) Write a note on Geiger-Muller Counter and Scintillation Counter. 05

Q.3 (a) Explain Phase diagram of 1 component and 3 phase system. 06


(b) Write a note on Carnot cycle. 05
(c) The heat of combustion of carbon monoxide at constant volume and at 170C is 05
-283.3 kJ. Calculate its heat of combustion at constant pressure. (R=8.314 J
degree-1mole-1)
CO (g) + ½ O2 (g) CO2 (g)

Q.4 (a) Explain following terms giving 3. Adiabatic process 06


suitable examples. (Any three) 4. Joule Thomson effect
1. Enthalpy
2. Entropy
(b) Write pharmaceutical applications of photochemistry. 05
(c) Differentiate: Ideal solution and real solution. 05

Q.5 (a) Define refractive index. How it is determined? Discuss pharmaceutical 06


applications of refractive index.
(b) 50% of a first order reaction is complete in 23 minutes. Calculate the time 05
required to complete 90% of the reaction.
(c) Define “Viscosity coefficient”. Explain principle of ostwald’s viscometer. 05

Q. 6 (a) Draw Jablonski diagram. State Beer’s law of photometry. Calculate absorbance 06
corresponding to 0, 10 & 100% transmission.
(b) Explain : Partition coefficient and freezing point depression with suitable 05
example.
(c) Write about various methods for the estimation of surface tension. 05

Q.7 (a) Enlist various methods for determination of order of kinetics. Discuss any two 06
methods.
(b) Write about Debye-Huckle theory. 05
(c) Explain characteristics of Enzyme catalysis. 05
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